3V3B

structure of the stapled p53 peptide bound to mdm2

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 48
  • Norm. En. per Res.: -3.4087
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	-2.2864	-57.4978	-59.7842	38	4	1	3401	0	13	15
A-D	-18.9696	0.0	-144.648	-163.6176	48	2	6	5531	0	1	4
B-C	-14.1861	0.0	-124.659	-138.8451	42	4	4	4824	0	1	4

Interface residues

• A-B: ARG105A, ARG105B, ASN106A, ASN106B, ASP46B, ASP80A, ASP80B, ASP84A, ASP84B, GLY83A, GLY87A, LEU33A, LEU33B, LEU34A, LEU34B, LEU35A, LEU35B, LEU37A, LEU37B, LEU81A, LEU81B, LEU82A, LEU85A, LEU85B, LYS31A, LYS31B, LYS36A, LYS36B, LYS39A, LYS39B, MET102A, MET102B, PHE86A, PRO32A, PRO32B, SER40B, VAL108A, VAL108B
• A-D: ARG24D, ARG65A, ARG97A, ASN21D, ASN29D, ASP68A, GLN17D, GLN28D, GLN59A, GLN71A, GLN72A, GLU69A, GLU95A, GLY58A, HIS73A, HIS96A, ILE103A, ILE61A, ILE74A, ILE99A, LEU22D, LEU25D, LEU26D, LEU54A, LEU57A, LEU66A, LEU82A, LYS51A, LYS70A, LYS94A, MET102A, MET50A, MET62A, PHE19D, PHE55A, PHE86A, PHE91A, SER92A, THR18D, THR63A, TRP23D, TYR100A, TYR56A, TYR60A, TYR67A, VAL53A, VAL75A, VAL93A
• B-C: ARG24C, ARG65B, ARG97B, ASN21C, ASP68B, GLN59B, GLN71B, GLN72B, GLU69B, GLU95B, GLY58B, HIS73B, HIS96B, ILE103B, ILE61B, ILE74B, ILE99B, LEU22C, LEU25C, LEU26C, LEU54B, LEU57B, LEU66B, LEU82B, LEU85B, LYS94B, MET62B, PHE19C, PHE55B, PHE86B, PHE91B, SER92B, THR18C, THR63B, TRP23C, TYR100B, TYR56B, TYR60B, TYR67B, VAL53B, VAL75B, VAL93B