3UVN

crystal structure of wdr5 in complex with the wdr5-interacting motif of set1a

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 72
  • Norm. En. per Res.: -3.855
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-49.1743	-19.0212	-209.366	-277.5616	72	7	5	7234	1	11	18
A-C	-37.0948	-18.7786	-137.925	-193.7984	69	6	0	4935	6	62	36
A-D	0.0	0.0	-0.0023	-0.0023	2	0	0	2	0	0	0
C-D	-36.7337	-18.1075	-199.049	-253.8902	66	11	5	6953	0	12	17

Interface residues

• A-B: ALA105A, ALA1494B, ALA176A, ALA264A, ALA320A, ALA47A, ALA65A, ARG1495B, ASN130A, ASN136A, ASN214A, ASP107A, ASP108A, ASP172A, ASP192A, ASP66A, ASP92A, CYS134A, CYS135A, CYS261A, GLU1497B, GLU258A, GLU279A, GLU322A, GLY147A, GLY1492B, GLY1498B, GLY193A, GLY89A, ILE262A, ILE305A, ILE90A, LEU234A, LEU321A, LEU88A, LYS259A, LYS46A, LYS52A, LYS67A, PHE133A, PHE149A, PHE219A, PHE263A, PRO173A, PRO215A, PRO216A, SER106A, SER148A, SER1493B, SER1496B, SER175A, SER218A, SER306A, SER49A, SER50A, SER63A, SER64A, SER91A, TYR131A, TYR1499B, TYR1500B, TYR191A, TYR260A, VAL132A, VAL174A, VAL177A, VAL217A, VAL220A, VAL303A, VAL48A, VAL51A, VAL93A
• A-C: ASN214A, ASN214C, ASN236A, ASN236C, ASN257A, ASN257C, ASP211A, ASP211C, ASP212A, ASP212C, ASP213A, ASP213C, ASP235A, ASP235C, CYS248A, CYS248C, GLN289A, GLN289C, GLU258A, GLU258C, GLU292A, GLU292C, GLY246A, GLY246C, GLY254A, GLY254C, HIS255A, HIS255C, ILE210A, ILE293A, ILE293C, LEU234A, LEU234C, LEU238A, LEU240A, LEU240C, LEU249A, LEU249C, LYS239A, LYS239C, LYS247A, LYS247C, LYS250A, LYS250C, LYS256A, LYS256C, LYS291A, LYS291C, LYS296A, LYS296C, PRO215A, PRO215C, PRO216A, PRO216C, THR233A, THR233C, THR237A, THR237C, THR251A, THR251C, THR253A, THR253C, TRP241A, TRP241C, TRP286A, TRP286C, TYR252A, TYR252C, TYR284A
• A-D: GLU292A, TYR1499D
• C-D: ALA105C, ALA1494D, ALA176C, ALA264C, ALA320C, ALA47C, ALA65C, ARG1495D, ASN130C, ASN136C, ASP107C, ASP108C, ASP172C, ASP66C, ASP92C, CYS134C, CYS135C, CYS261C, GLU1497D, GLU258C, GLU279C, GLU322C, GLY147C, GLY1492D, GLY1498D, GLY89C, ILE262C, ILE305C, ILE90C, LEU234C, LEU321C, LEU88C, LYS259C, LYS46C, LYS52C, LYS67C, PHE133C, PHE149C, PHE219C, PHE263C, PRO173C, PRO216C, SER106C, SER148C, SER1493D, SER1496D, SER175C, SER218C, SER306C, SER49C, SER50C, SER63C, SER64C, SER91C, TYR131C, TYR1499D, TYR191C, TYR260C, VAL132C, VAL174C, VAL177C, VAL220C, VAL303C, VAL48C, VAL51C, VAL93C