3UO9

crystal structure of human gac in complex with glutamate and bptes

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 56
  • Norm. En. per Res.: -3.2487
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-8.3845	-7.2841	-161.773	-177.4416	57	1	8	6084	2	23	27
A-C	-48.8186	-62.437	-457.981	-569.2366	200	19	2	17350	7	46	54
A-D	0.0	5.0768	-7.5251	-2.4483	7	1	0	276	0	0	4
B-D	-51.6938	-56.9213	-444.042	-552.6571	193	20	2	16882	10	46	53
C-D	-7.6799	-16.1712	-158.074	-181.9251	56	0	8	5895	2	23	28

Interface residues

• A-B: ALA390A, ALA390B, ARG317A, ARG382A, ARG382B, ARG387A, ARG387B, ASN324A, ASN324B, ASN388A, ASN388B, ASP327A, ASP327B, ASP386A, ASP386B, GLU325A, GLU325B, GLU383A, GLU383B, GLU397A, GLU397B, GLY385A, GLY385B, GLY392A, GLY392B, HIS330A, ILE391A, ILE391B, LEU321A, LEU321B, LEU323A, LEU323B, LEU395A, LEU395B, LYS320A, LYS320B, LYS396A, LYS396B, LYS398A, LYS398B, LYS399A, LYS399B, MET407A, MET407B, PHE318A, PHE322A, PHE322B, PHE389A, PHE389B, SER384A, SER384B, TYR393A, TYR393B, TYR394A, TYR394B, VAL408A, VAL408B
• A-C: ALA432A, ALA432C, ALA435A, ALA435C, ALA452A, ALA452C, ALA473A, ALA473C, ALA480A, ALA480C, ALA537A, ALA537C, ARG174A, ARG174C, ARG317A, ARG446A, ARG446C, ARG454A, ARG454C, ARG534A, ARG534C, ARG543A, ARG543C, ASN319A, ASN319C, ASN324A, ASN324C, ASN331A, ASN331C, ASN436A, ASN436C, ASN455A, ASN455C, ASN494A, ASN494C, ASN526A, ASN526C, ASN529A, ASN529C, ASN532A, ASN532C, ASP269A, ASP269C, ASP326A, ASP326C, ASP327C, ASP467A, ASP467C, ASP531A, ASP531C, CYS440A, CYS440C, CYS525A, GLN213A, GLN213C, GLN271A, GLN471A, GLN471C, GLU303A, GLU303C, GLU312A, GLU312C, GLU325A, GLU325C, GLU451A, GLU451C, GLY270A, GLY270C, GLY310A, GLY310C, GLY315A, GLY437A, GLY437C, GLY438A, GLY438C, GLY444A, GLY444C, GLY470A, GLY470C, GLY477A, GLY477C, HIS306A, HIS306C, HIS330A, HIS330C, HIS461A, HIS461C, HIS475A, HIS475C, HIS519A, HIS519C, HIS528A, HIS528C, HIS535A, HIS535C, ILE221A, ILE221C, LEU210C, LEU316A, LEU321C, LEU323C, LEU434A, LEU434C, LEU457A, LEU457C, LEU459A, LEU459C, LEU478A, LEU478C, LEU533A, LEU533C, LYS218A, LYS218C, LYS311A, LYS311C, LYS320C, LYS328A, LYS328C, LYS538A, LYS538C, LYS539A, LYS539C, MET333A, MET333C, MET460A, MET460C, MET508A, MET508C, PHE219A, PHE219C, PHE318A, PHE318C, PHE439A, PHE439C, PHE468A, PHE468C, PHE472A, PHE472C, PHE474A, PHE474C, PHE527A, PHE527C, PHE536A, PHE536C, PRO313A, PRO313C, PRO332A, PRO332C, PRO441A, PRO441C, PRO450A, PRO450C, PRO479A, PRO479C, PRO493A, PRO493C, SER314A, SER314C, SER449A, SER449C, SER458A, SER458C, SER462A, SER462C, SER469A, SER469C, SER523A, SER523C, THR267A, THR267C, THR302A, THR302C, THR433A, THR433C, THR456A, THR456C, TYR293A, TYR293C, TYR530A, TYR530C, VAL220A, VAL220C, VAL268A, VAL268C, VAL297A, VAL297C, VAL305A, VAL305C, VAL453A, VAL453C, VAL476A, VAL476C, VAL491A, VAL491C, VAL492A, VAL492C, VAL495A, VAL495C, VAL522A, VAL522C
• A-D: ARG317A, ARG317D, LEU321A, LEU321D, LYS320A, LYS320D, PHE318D
• B-D: ALA432D, ALA435B, ALA435D, ALA452B, ALA452D, ALA473B, ALA473D, ALA480B, ALA480D, ALA537B, ALA537D, ARG174B, ARG174D, ARG317D, ARG446B, ARG446D, ARG454B, ARG454D, ARG534B, ARG534D, ARG543B, ARG543D, ARG544B, ARG544D, ASN319D, ASN324B, ASN324D, ASN331B, ASN331D, ASN436B, ASN436D, ASN455B, ASN455D, ASN494B, ASN494D, ASN526B, ASN526D, ASN529B, ASN529D, ASN532B, ASN532D, ASP269B, ASP269D, ASP326B, ASP327B, ASP467B, ASP467D, ASP531B, ASP531D, CYS525B, CYS525D, GLN213B, GLN213D, GLN471B, GLN471D, GLU303B, GLU303D, GLU312B, GLU312D, GLU325B, GLU451B, GLU451D, GLY270B, GLY270D, GLY310B, GLY310D, GLY315D, GLY437B, GLY437D, GLY438B, GLY438D, GLY444B, GLY444D, GLY470B, GLY470D, GLY477B, GLY477D, HIS306B, HIS306D, HIS330B, HIS461B, HIS461D, HIS475B, HIS475D, HIS519B, HIS519D, HIS528B, HIS528D, HIS535B, HIS535D, ILE221B, ILE221D, LEU316D, LEU321B, LEU323B, LEU434B, LEU434D, LEU457B, LEU457D, LEU459B, LEU459D, LEU478B, LEU478D, LEU533B, LEU533D, LYS218B, LYS218D, LYS311B, LYS311D, LYS320D, LYS328D, LYS538B, LYS538D, LYS539B, LYS539D, MET333B, MET333D, MET460B, MET460D, MET508B, MET508D, PHE219B, PHE219D, PHE318D, PHE439B, PHE439D, PHE468B, PHE468D, PHE472B, PHE472D, PHE474B, PHE474D, PHE527B, PHE527D, PHE536B, PHE536D, PRO313B, PRO313D, PRO332B, PRO332D, PRO441B, PRO441D, PRO450B, PRO450D, PRO479B, PRO479D, PRO493B, PRO493D, SER314B, SER314D, SER449B, SER449D, SER458B, SER458D, SER462B, SER462D, SER469B, SER469D, SER523B, SER523D, THR267B, THR267D, THR302B, THR302D, THR433B, THR433D, THR456B, THR456D, TYR293B, TYR293D, TYR530B, TYR530D, VAL220B, VAL220D, VAL268B, VAL268D, VAL297B, VAL297D, VAL305B, VAL305D, VAL309B, VAL453B, VAL453D, VAL476B, VAL476D, VAL491B, VAL491D, VAL492B, VAL492D, VAL495B, VAL495D, VAL522B, VAL522D
• C-D: ALA390C, ALA390D, ARG317D, ARG382C, ARG387C, ARG387D, ASN319C, ASN324C, ASN324D, ASN388C, ASN388D, ASP327D, ASP386C, ASP386D, GLU325C, GLU325D, GLU383C, GLU383D, GLU397C, GLU397D, GLY385C, GLY385D, GLY392C, GLY392D, ILE391C, ILE391D, LEU321C, LEU321D, LEU323C, LEU323D, LEU395C, LEU395D, LYS320C, LYS320D, LYS396C, LYS396D, LYS398C, LYS398D, LYS399C, LYS399D, MET407C, MET407D, PHE318D, PHE322C, PHE322D, PHE389C, PHE389D, SER384C, SER384D, TYR249D, TYR393C, TYR393D, TYR394C, TYR394D, VAL408C, VAL408D