3U8Z

human merlin ferm domain

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 247
  • Norm. En. per Res.: -3.7932
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-45.892	-31.6228	-193.42	-270.9348	108	8	0	7637	6	50	46
A-C	-130.045	21.7642	-828.632	-936.9128	247	31	5	30739	5	112	108
A-D	0.0	0.0	-0.011	-0.011	2	0	0	9	0	1	0
B-C	0.0	0.0	-0.0225	-0.0225	4	0	0	18	0	1	1
B-D	-58.211	24.5732	-457.572	-491.2097	158	20	4	17863	2	70	68

Interface residues

• A-B: ALA142A, ALA142B, ALA223A, ALA223B, ARG225A, ARG225B, ARG249A, ARG249B, ARG291A, ARG291B, ASN226A, ASN226B, ASN248A, ASN248B, ASN286A, ASN286B, ASP128A, ASP128B, ASP245A, ASP245B, ASP70A, ASP70B, CYS133A, CYS133B, GLN125A, GLN125B, GLN65A, GLN65B, GLU129A, GLU129B, GLU215A, GLU215B, GLU231A, GLU231B, GLU247A, GLU247B, GLU32B, GLY229A, GLY229B, HIS95A, HIS95B, ILE126A, ILE126B, ILE131A, ILE131B, ILE224A, ILE224B, LEU127A, LEU127B, LEU141A, LEU141B, LEU214A, LEU214B, LEU232A, LEU232B, LEU233A, LEU233B, LEU250A, LEU250B, LEU97A, LYS123A, LYS123B, LYS124A, LYS124B, LYS130A, LYS130B, LYS228A, LYS228B, LYS269A, LYS269B, LYS289A, LYS289B, LYS69A, LYS69B, MET216A, MET216B, PHE222A, PHE222B, PRO134A, PRO134B, PRO135A, PRO135B, PRO246A, PRO246B, SER138A, SER138B, SER287A, SER287B, SER288A, SER288B, THR230A, THR230B, THR251A, THR251B, THR67A, THR67B, THR71B, TYR132A, TYR132B, TYR221A, TYR221B, TYR244B, VAL139A, VAL139B, VAL27A, VAL27B, VAL292A, VAL292B
• A-C: ALA145C, ALA148A, ALA148C, ALA190A, ALA190C, ALA193A, ALA193C, ALA199A, ALA199C, ALA203C, ALA31A, ALA31C, ARG187A, ARG187C, ARG196A, ARG196C, ARG198A, ARG198C, ARG200A, ARG200C, ARG25A, ARG25C, ARG262A, ARG262C, ARG309A, ARG309C, ARG310A, ARG310C, ARG311A, ARG52A, ARG52C, ARG57A, ARG57C, ASN263A, ASN263C, ASN293A, ASN293C, ASN303A, ASN303C, ASN36A, ASN36C, ASP152A, ASP152C, ASP154C, ASP201A, ASP201C, ASP268A, ASP268C, ASP305A, ASP305C, ASP30A, ASP30C, ASP45A, ASP45C, ASP48A, ASP48C, ASP78A, ASP78C, CYS300A, CYS300C, CYS51A, CYS51C, GLN111A, GLN111C, GLN115A, GLN115C, GLN147A, GLN147C, GLN178A, GLN178C, GLN298A, GLN298C, GLU112A, GLU112C, GLU182A, GLU182C, GLU185A, GLU185C, GLU186A, GLU186C, GLU194A, GLU194C, GLU204A, GLU204C, GLU270A, GLU270C, GLU32A, GLU32C, GLU34A, GLU34C, GLU38A, GLU38C, GLU58A, GLU58C, GLY151A, GLY151C, GLY197A, GLY197C, GLY302A, GLY302C, GLY43A, GLY55A, GLY55C, GLY63A, GLY63C, HIS116A, HIS116C, HIS158C, HIS195A, HIS195C, HIS304A, HIS304C, ILE113A, ILE113C, ILE188A, ILE188C, ILE261A, ILE261C, ILE264A, ILE264C, ILE26A, ILE26C, ILE273A, ILE296A, ILE296C, ILE301A, ILE301C, LEU117A, LEU117C, LEU120A, LEU120C, LEU241A, LEU241C, LEU290A, LEU290C, LEU295A, LEU295C, LEU297A, LEU297C, LEU299A, LEU299C, LEU306A, LEU306C, LEU46A, LEU49A, LEU49C, LEU54A, LEU54C, LEU56A, LEU56C, LEU75C, LYS149A, LYS149C, LYS20A, LYS269A, LYS269C, LYS274A, LYS274C, LYS294A, LYS294C, LYS312A, LYS312C, LYS40A, LYS42A, LYS44A, LYS44C, LYS76A, LYS76C, LYS80A, LYS99A, LYS99C, MET179A, MET179C, MET183A, MET183C, MET29A, MET29C, MET308A, MET308C, MET33A, MET33C, MET77A, MET77C, PHE100A, PHE100C, PHE119A, PHE119C, PHE271A, PHE271C, PHE307A, PHE307C, PHE35A, PHE35C, PHE47A, PHE47C, PHE61A, PHE61C, PHE62A, PHE62C, PRO181A, PRO181C, SER265A, SER265C, SER267A, SER267C, THR114A, THR114C, THR180A, THR180C, THR189A, THR189C, THR21A, THR23A, THR23C, THR272A, THR272C, THR28A, THR28C, THR53A, THR53C, THR59A, THR59C, TRP184A, TRP184C, TRP191A, TRP191C, TRP258A, TRP258C, TRP41A, TRP41C, TRP60A, TRP60C, TYR150A, TYR150C, TYR153C, TYR192A, TYR192C, TYR266A, TYR266C, VAL110A, VAL110C, VAL146C, VAL236A, VAL24A, VAL27C, VAL50A, VAL50C
• A-D: ASN36D, LYS69A
• B-C: ASN36C, LEU290B, LYS20C, LYS69B
• B-D: ALA148B, ALA148D, ALA190B, ALA193B, ALA199B, ALA199D, ALA31B, ALA31D, ARG187B, ARG196B, ARG198B, ARG200B, ARG200D, ARG25B, ARG25D, ARG262D, ARG309D, ARG310D, ARG52B, ARG52D, ARG57B, ARG57D, ASN259D, ASN263D, ASN293D, ASN303D, ASN36B, ASN36D, ASP152B, ASP201B, ASP201D, ASP268D, ASP305D, ASP30B, ASP30D, ASP45B, ASP48B, ASP48D, ASP78D, CYS300D, CYS51B, CYS51D, GLN111B, GLN111D, GLN115B, GLN115D, GLN178B, GLN298D, GLU112B, GLU112D, GLU182B, GLU185B, GLU186B, GLU194B, GLU204B, GLU204D, GLU32B, GLU32D, GLU34B, GLU34D, GLU38B, GLU38D, GLU58D, GLY151B, GLY197B, GLY302D, GLY55B, GLY55D, GLY63D, HIS116B, HIS116D, HIS195B, HIS304D, ILE113B, ILE113D, ILE188B, ILE261D, ILE264D, ILE26B, ILE26D, ILE296D, ILE301D, LEU117B, LEU117D, LEU120B, LEU120D, LEU241D, LEU276D, LEU295D, LEU297D, LEU299D, LEU306D, LEU49B, LEU49D, LEU54B, LEU54D, LEU56B, LEU56D, LYS149B, LYS149D, LYS274D, LYS294D, LYS312D, LYS44B, LYS44D, LYS76D, LYS99D, MET179B, MET183B, MET29B, MET29D, MET308D, MET33B, MET33D, MET77D, PHE100D, PHE119B, PHE119D, PHE271D, PHE307D, PHE35B, PHE35D, PHE47B, PHE47D, PHE61D, PHE62D, PRO181B, SER265D, SER267D, THR114B, THR114D, THR180B, THR189B, THR23B, THR23D, THR272D, THR28B, THR28D, THR53B, THR53D, THR59B, THR59D, TRP184B, TRP191B, TRP258D, TRP41B, TRP41D, TRP60D, TYR150B, TYR150D, TYR192B, TYR266D, VAL110B, VAL110D, VAL24B, VAL24D, VAL50B, VAL50D