3U7X

crystal structure of the human eif4e-4ebp1 peptide complex without cap

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 47
  • Norm. En. per Res.: -4.1977
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	34.8484	-87.3309	-52.4826	58	14	3	4499	0	22	23
A-C	-27.6255	-12.6549	-152.735	-193.0154	48	5	4	6167	1	20	20
B-D	-31.5063	-8.0469	-157.74	-197.2932	47	6	4	6413	0	21	20

Interface residues

• A-B: ALA201A, ALA201B, ALA204A, ALA204B, ALA58A, ALA58B, ARG109A, ARG109B, ARG214A, ARG214B, ASN107A, ASN107B, ASN59A, ASN59B, ASP104A, ASP104B, ASP202A, ASP202B, GLN57A, GLN57B, GLU103A, GLU103B, GLU105A, GLU105B, GLU169A, GLU169B, GLU171A, GLU171B, GLY110A, GLY110B, GLY208A, GLY208B, HIS200A, HIS200B, LYS108A, LYS108B, LYS206A, LYS206B, LYS54A, LYS54B, MET101A, MET101B, SER199A, SER199B, SER207A, SER207B, SER209A, SER209B, THR203A, THR203B, THR205A, THR205B, THR55A, THR55B, TRP102A, TRP102B, TRP56A, TRP56B
• A-C: ALA74A, ARG128A, ARG186A, ARG51C, ARG56C, ARG63C, ASN41A, ASN77A, ASP143A, ASP144A, ASP147A, ASP55C, ASP67A, CYS136A, CYS62C, GLN40A, GLU132A, GLU140A, GLU32A, GLU61C, GLU70A, GLY139A, HIS37A, ILE138A, ILE35A, ILE52C, ILE53C, LEU131A, LEU134A, LEU135A, LEU137A, LEU39A, LEU59C, LYS36A, LYS57C, MET60C, PHE142A, PHE58C, PHE72A, PRO38A, SER141A, SER146A, THR50C, THR68A, TRP73A, TYR54C, TYR76A, VAL69A
• B-D: ALA74B, ARG128B, ARG186B, ARG51D, ARG56D, ARG63D, ASN41B, ASN77B, ASP143B, ASP144B, ASP147B, ASP55D, ASP67B, CYS136B, CYS62D, GLN40B, GLU132B, GLU140B, GLU32B, GLU61D, GLU70B, GLY139B, HIS37B, ILE138B, ILE52D, ILE53D, LEU131B, LEU134B, LEU135B, LEU137B, LEU39B, LEU59D, LYS36B, LYS57D, MET60D, PHE142B, PHE58D, PHE72B, PRO38B, SER141B, SER146B, THR50D, THR68B, TRP73B, TYR54D, TYR76B, VAL69B