3U6R

three dimensional structure of broadly neutralizing anti - hepatitis c virus (hcv) glycoprotein e2 single chain fv fragment 1:7

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: H-L
  • Int. Res.: 89
  • Norm. En. per Res.: -4.2271
• Hub Node: H(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
H-L	-61.6597	0.0	-314.55	-376.2097	89	13	7	10548	0	7	8
H-A	0.0	0.0	-0.1542	-0.1542	13	0	0	98	0	0	0
H-B	-8.196	7.9737	-87.3935	-87.6158	41	4	0	3017	0	5	7
L-A	-6.3718	7.9785	-81.8929	-80.2862	40	3	0	2772	0	5	7
L-B	0.0	0.0	-18.1453	-18.1453	10	0	0	554	0	0	3
A-B	-26.8416	25.7292	-263.556	-264.6684	85	9	7	9295	0	8	7

Interface residues

• H-L: ALA100H, ALA107H, ALA182L, ALA191L, ALA199L, ALA203L, ALA43H, ALA64H, ARG101H, ARG109H, ARG193L, ARG239L, ARG41H, ASN106H, ASN178L, ASN201L, ASN53H, ASN62H, ASP117H, ASP198L, ASP241L, CYS236L, CYS99H, GLN121H, GLN154L, GLN175L, GLN186L, GLN190L, GLN237L, GLN238L, GLN38H, GLN42H, GLN46H, GLN9H, GLU49H, GLY113H, GLY120H, GLY122H, GLY189L, GLY246L, GLY247L, GLY248L, GLY45H, GLY47H, GLY52H, HIS110H, ILE104H, ILE108H, ILE196L, ILE55H, LEU181L, LEU194L, LEU195L, LEU40H, LYS179L, MET112H, MET51H, PHE116H, PHE245L, PHE98H, PRO105H, PRO192L, PRO48H, PRO56H, SER200L, SER240L, THR111H, THR204L, THR244L, TRP119H, TRP183L, TRP242L, TRP39H, TRP50H, TYR114H, TYR115H, TYR118H, TYR180L, TYR184L, TYR197L, TYR235L, TYR35H, VAL102H, VAL103H, VAL177L, VAL233L, VAL243L, VAL4H, VAL96H
• H-A: ALA12A, ALA12H, GLY45A, GLY45H, LEU124A, LEU124H, PRO44A, PRO44H, THR126A, THR126H, THR94A, VAL14A, VAL14H
• H-B: ALA12H, ALA232B, ASP230B, GLN121H, GLN190B, GLN26H, GLN5H, GLN9H, GLU227B, GLU229B, GLU252B, GLU8H, GLY11H, GLY120H, GLY122H, GLY189B, GLY29H, ILE253B, LEU124H, LEU161B, LEU6H, LEU7H, LYS187B, LYS250B, LYS254B, PHE231B, PHE28H, PRO163B, PRO188B, PRO228B, SER10H, SER160B, SER162B, SER80H, THR123H, THR79H, THR81H, TRP119H, VAL251B, VAL27H, VAL96H
• L-A: ALA12A, ALA232L, ASP230L, GLN121A, GLN190L, GLN26A, GLN5A, GLN9A, GLU227L, GLU229L, GLU252L, GLU8A, GLY11A, GLY120A, GLY122A, GLY189L, GLY29A, ILE253L, LEU124A, LEU161L, LEU6A, LEU7A, LYS187L, LYS250L, LYS254L, PHE231L, PHE28A, PRO163L, PRO188L, PRO228L, SER10A, SER160L, SER162L, THR123A, THR79A, THR81A, TRP119A, VAL251L, VAL27A, VAL96A
• L-B: ALA191B, ALA191L, GLN190B, GLN190L, GLY189B, GLY189L, LYS187B, LYS187L, PRO188B, PRO188L
• A-B: ALA100A, ALA182B, ALA191B, ALA199B, ALA203B, ALA43A, ALA64A, ARG101A, ARG109A, ARG193B, ARG239B, ARG41A, ASN106A, ASN201B, ASN53A, ASN62A, ASP117A, ASP198B, ASP241B, CYS236B, CYS99A, GLN121A, GLN154B, GLN186B, GLN190B, GLN237B, GLN238B, GLN38A, GLN42A, GLN46A, GLN65A, GLN9A, GLU49A, GLY113A, GLY120A, GLY122A, GLY189B, GLY246B, GLY247B, GLY248B, GLY45A, GLY47A, GLY52A, HIS110A, ILE196B, ILE55A, LEU181B, LEU194B, LEU195B, LEU40A, LYS179B, MET112A, MET2A, MET51A, PHE116A, PHE245B, PHE98A, PRO105A, PRO192B, PRO48A, SER200B, SER240B, THR111A, THR204B, THR244B, TRP119A, TRP183B, TRP242B, TRP39A, TRP50A, TYR114A, TYR115A, TYR118A, TYR180B, TYR184B, TYR197B, TYR235B, TYR63A, VAL102A, VAL103A, VAL177B, VAL233B, VAL243B, VAL4A, VAL96A