3U5E

the structure of the eukaryotic ribosome at 3.0 a resolution. this entry contains proteins of the 60s subunit, ribosome a

• Total interactions analyzed: 820
• Total true interactions: 90
• Strongest Interaction:
  • Chains: L-N
  • Int. Res.: 36
  • Norm. En. per Res.: -5.9326
• Hub Node: C(13)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-G	-14.407	0.0	-66.2949	-80.7019	35	3	4	2992	0	4	2
A-N	0.0	0.0	-2.0568	-2.0568	7	0	0	177	0	0	2
A-Z	0.0	0.0	-0.1464	-0.1464	2	0	0	21	0	0	0
A-g	0.0	0.0	-0.0837	-0.0837	9	0	0	51	0	1	0
A-p	-83.9829	-13.7419			24
B-O	-10.5097	2.2602	288.256	280.0065	72	38	1	4516	0	9	15
B-P	0.0	0.0	-0.0047	-0.0047	2	0	0	5	0	0	1
B-V	-4.6069	-16.1013	-101.481	-122.1891	56	5	2	4686	1	23	30
B-W	-12.7159	-29.7406	-110.801	-153.2574	66	2	1	5304	2	15	18
C-E	0.0	0.0	-0.4847	-0.4847	10	0	0	181	0	0	7
C-F	-18.5789	-22.6105	-269.092	-310.2814	105	10	6	11705	1	22	34
C-L	0.0	0.0	-47.8332	-47.8332	24	1	1	1718	0	7	11
C-N	-20.7887	3.4157	-66.7148	-84.0878	25	2	0	2614	0	0	14
C-Q	-54.043	23.0277	-270.178	-301.1933	91	13	15	13023	0	15	15
C-S	-19.3107	-16.5806	-47.6043	-83.4956	29	10	1	2571	1	11	12
C-T	0.0	0.0	-18.3928	-18.3928	19	3	1	991	0	0	1
C-Y	-3.2314	35.5526	-28.4315	3.8897	22	1	0	1253	0	4	19
C-a	0.0	0.0	-0.1054	-0.1054	8	0	0	53	0	0	0
C-e	0.0	0.0	-0.0056	-0.0056	2	0	0	4	0	0	2
C-j	-15.551	0.0	-6.4621	-22.0131	13	4	0	581	0	0	6
D-I	0.0	-3.3001	-36.1161	-39.4162	29	5	5	2129	0	2	7
D-J	-6.5268	14.6443	-47.4231	-39.3056	37	2	0	2469	0	10	22
D-T	-26.4048	5.5615	-205.131	-225.9742	77	7	6	8578	0	7	38
D-b	0.0	0.0	-0.6284	-0.6284	7	0	0	149	0	3	3
E-M	-39.2898	-43.6557	-116.96	-199.9055	48	11	3	5397	2	15	13
E-O	0.0	0.0	-0.0761	-0.0761	5	0	0	24	0	0	0
E-P	0.0	0.0	-0.905	-0.905	15	0	0	214	0	3	9
E-S	0.0	0.0	-0.0814	-0.0814	2	0	0	33	0	0	1
E-e	-10.8568	-10.9075	-123.25	-145.0143	46	4	4	4657	0	12	5
E-f	-39.8871	-23.5325	-254.207	-317.6265	72	8	11	10225	2	11	24
F-Q	-10.2278	-40.5095	-65.0254	-115.7627	25	4	1	2405	3	9	7
F-S	-6.5383	-6.9856	-84.4295	-97.9534	60	4	7	3902	2	13	17
F-T	-77.7233	-4.1596	-159.529	-241.4118	46	13	4	6004	0	6	11
F-b	0.0	0.0	-0.0027	-0.0027	6	0	0	8	0	0	7
G-N	-33.8549	-13.5653	-233.126	-280.5462	92	7	11	10431	6	32	26
G-X	-25.7263	0.0	-95.611	-121.3373	27	4	4	3740	0	1	8
G-Z	0.0	0.0	-33.286	-33.286	30	1	1	1757	0	0	9
G-g	0.0	0.0	-0.0064	-0.0064	3	0	0	4	0	0	0
G-i	-13.0226	-52.1762	-30.2235	-95.4223	37	4	6	2885	2	7	7
H-M	-21.6723	-3.4227	-131.722	-156.817	58	14	3	5208	0	7	11
H-O	0.0	0.5345	-2.7334	-2.1989	15	0	0	227	0	7	14
H-S	-13.2237	-4.5672	-59.8891	-77.68	31	8	1	2517	0	4	11
H-m	-7.4784	1.7053	-144.395	-150.1681	58	5	7	6473	0	14	27
I-S	-11.387	0.0	-10.1341	-21.5211	10	0	0	413	0	2	2
I-T	-7.8228	-7.4746	-40.3296	-55.627	27	5	1	2148	0	2	1
I-b	0.0	0.0	-0.1562	-0.1562	4	0	0	64	0	0	1
J-o	-7.3139	0.0	0.0	-7.3139	2	0	0	0	0	0	0
L-N	-66.8676	-0.2642	-146.441	-213.5728	36	10	3	5455	0	4	24
L-Q	0.0	0.0	-49.7041	-49.7041	23	1	0	2019	0	1	4
L-Y	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	0
L-a	-42.2724	-29.5436	-399.558	-471.3741	126	18	13	15228	5	23	44
L-h	-34.3769	9.2684	-268.637	-293.7455	63	21	14	10503	0	5	12
L-i	-11.7197	7.5045	-153.091	-157.3062	64	11	5	6213	0	8	21
M-O	-27.5876	0.0	-183.043	-210.6306	61	4	12	8730	0	5	7
M-S	-48.879	-7.4446	-243.667	-299.9906	83	9	11	10317	2	27	33
M-f	0.0	0.0	-0.0318	-0.0318	2	0	0	11	0	2	0
N-a	0.0	2.6413	-0.1725	2.4688	3	0	0	36	0	0	3
N-h	-16.2321	-38.8707	-83.2477	-138.3505	39	5	1	3938	1	14	21
N-i	0.0	3.6697	-106.292	-102.6223	43	4	5	5197	1	18	18
N-j	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	0	1
N-o	0.0	0.0	-41.5115	-41.5115	21	0	0	1331	0	0	0
O-S	-39.039	-15.9208	-133.532	-188.4918	66	7	5	7062	1	6	20
O-V	0.0	0.0	-1.625	-1.625	4	0	0	50	0	0	0
O-f	0.0	0.0	-31.2879	-31.2879	34	0	0	1904	0	1	11
O-m	0.0	0.0	-0.0283	-0.0283	2	0	0	11	0	0	1
P-d	0.0	0.0	-0.0334	-0.0334	4	0	0	11	0	4	5
P-f	-16.6145	0.0	-27.8453	-44.4598	19	7	0	1466	0	4	9
P-j	0.0	0.0	-0.0009	-0.0009	3	0	0	3	0	0	1
Q-a	-49.0643	-74.4679	-211.088	-334.6202	86	15	2	9046	6	33	52
Q-b	0.0	0.0	-0.6172	-0.6172	3	0	0	103	0	2	7
R-X	0.0	0.0	-0.001	-0.001	3	0	0	3	0	1	1
S-T	-76.7829	-37.147	-226.916	-340.8459	76	14	4	9341	3	11	8
S-f	0.0	0.0	-0.0623	-0.0623	6	0	0	23	0	2	1
T-b	-14.4226	1.8755	-109.608	-122.155	53	5	1	4514	0	7	16
V-W	-36.8251	0.0141	-118.531	-155.3419	50	6	6	4864	0	13	11
X-h	0.0	-16.053	-178.16	-194.213	81	7	7	7804	1	14	19
X-l	-14.1748	0.0	-42.6084	-56.7832	19	3	0	1995	0	0	8
Y-j	0.0	0.0	-1.292	-1.292	6	0	1	120	0	0	0
Y-l	0.0	0.0	-10.4274	-10.4274	11	0	0	536	0	0	1
Z-c	-9.9131	-2.9062	-137.265	-150.0842	50	11	1	5471	0	10	18
Z-g	-20.3792	4.7516	-151.86	-167.4875	54	13	12	7106	0	12	22
a-e	0.0	4.4599	-24.7123	-20.2524	16	1	0	1046	0	1	15
a-i	0.0	0.0	-40.8497	-40.8497	24	0	4	1821	0	3	8
a-o	0.0	0.0	-11.3396	-11.3396	7	1	0	438	0	0	3
c-g	-9.4839	0.0	-60.6142	-70.0981	30	4	2	2624	0	9	10
c-p	-5.1431	4.7699			4
e-f	0.0	7.7307	-6.069	1.6617	5	0	0	328	0	0	3
g-l	0.0	0.0	-7.9324	-7.9324	6	1	0	327	0	0	1
h-j	0.0	5.8552	-27.8471	-21.9919	22	0	1	1493	0	0	13
j-l	0.0	0.0	-44.666	-44.666	21	4	1	2022	0	0	15

Interface residues

• A-G: ALA35A, ALA39G, ALA90A, ARG30A, ARG37A, ARG42A, ARG44G, ARG64A, ARG70A, ASN33G, ASP33A, ASP65A, GLN38G, GLN41G, GLU36A, GLY35G, GLY37G, GLY39A, GLY91A, HIS38A, ILE36G, ILE41A, LEU46G, LYS43G, LYS68A, LYS93A, PHE34G, PRO42G, PRO66A, TYR34A, TYR40A, TYR49G, TYR67A, TYR69A, VAL40G
• A-N: ARG3A, ARG9A, GLN8A, ILE5A, LYS77N, SER231A, VAL4A
• A-Z: ARG135Z, TYR69A
• A-g: ARG42A, ARG80g, ARG88g, ARG91g, ASP46g, GLY45g, ILE95g, LYS46A, PHE87A
• A-p: ALA65p, ALA68p, ARG174A, ARG17p, ARG184A, ARG80p, ASP176A, GLU30p, GLU80A, GLY171A, GLY172A, GLY66p, GLY81A, HIS83A, LYS177A, LYS181A, LYS28p, LYS62p, THR63p, THR73p, THR84A, TYR14p, TYR69p, VAL82A
• B-O: ALA154O, ALA23B, ALA258B, ALA63O, ALA75O, ARG163O, ARG28B, ARG348B, ARG58B, ARG62B, ARG68O, ARG70B, ARG97B, ASN65O, ASP151O, ASP59B, ASP61B, GLU106O, GLU150O, GLU157O, GLU352B, GLU71B, GLU94B, GLY107O, GLY64B, GLY98B, HIS259B, HIS68B, HIS9O, ILE108O, LEU14B, LEU156O, LEU351B, LEU60B, LEU99B, LYS148O, LYS155O, LYS159O, LYS66B, LYS66O, LYS69B, MET261B, PHE105O, PHE64O, PHE67B, PRO109O, PRO110O, PRO257B, PRO63B, PRO76O, PRO96B, SER156B, SER263B, SER65B, SER77O, THR62O, THR67O, THR95B, TRP147O, TRP1O, TRP262B, TYR149O, TYR154B, TYR8O, VAL152O, VAL153O, VAL260B, VAL264B, VAL3O, VAL72B, VAL8O, VAL93B
• B-P: ARG21B, ARG69P
• B-V: ALA123V, ALA75B, ALA8B, ARG10B, ARG45V, ARG48V, ARG4B, ARG58B, ARG62B, ARG70B, ARG86V, ARG87V, ARG88V, ASN47V, ASP124V, ASP89V, CYS122V, GLU121V, GLU71B, GLU74B, GLU7B, GLY119V, GLY12B, GLY234B, GLY64B, GLY8V, GLY90V, HIS11B, HIS68B, ILE13V, ILE56B, LEU125V, LEU46V, LEU60B, LYS10V, LYS120V, LYS236B, LYS349B, LYS5B, LYS66B, PHE11V, PHE67B, PHE92V, PRO9B, SER44V, SER65B, THR235B, THR55B, THR9V, TRP233B, TYR6B, VAL137V, VAL57B, VAL72B, VAL73B, VAL91V
• B-W: ALA11W, ALA362B, ALA378B, ARG17W, ARG369B, ARG56W, ARG58B, ASN33W, ASP299B, ASP360B, ASP59B, ASP6W, GLN32W, GLN371B, GLU375B, GLU71B, GLU74B, GLY10W, GLY16W, GLY18W, GLY366B, GLY368B, GLY381B, GLY62W, ILE13W, ILE359B, ILE56B, ILE5W, ILE63W, LEU383B, LYS12W, LYS2W, LYS303B, LYS357B, LYS35W, LYS364B, LYS367B, LYS376B, LYS61W, MET1W, MET380B, PHE298B, PHE370B, PHE379B, PRO15W, SER34W, SER363B, SER36W, SER9W, THR19W, THR301B, THR361B, THR372B, THR382B, THR52W, THR54B, THR55B, THR64W, TRP358B, TRP51W, TYR14W, VAL3W, VAL53W, VAL57B, VAL72B, VAL73B
• C-E: ARG22E, ARG309C, ARG326C, GLN322C, LEU313C, LYS19E, LYS23E, LYS308C, LYS315C, VAL312C
• C-F: ALA167F, ALA331C, ALA344C, ALA352C, ALA353C, ALA42F, ALA49F, ALA50F, ALA69F, ALA71F, ALA72F, ARG145F, ARG151F, ARG160F, ARG326C, ARG33F, ARG41F, ARG47F, ARG60F, ARG67F, ASN166F, ASN244F, ASN316C, ASN328C, ASN48F, ASP165F, ASP182F, ASP183F, ASP68F, GLN146F, GLN322C, GLN52F, GLN64F, GLU345C, GLU46F, GLU56F, GLY152F, GLY340C, GLY348C, GLY73F, HIS311C, ILE168F, ILE169F, ILE181F, ILE185F, ILE43F, ILE44F, ILE63F, LEU147F, LEU163F, LEU313C, LEU318C, LEU324C, LEU325C, LEU327C, LEU339C, LEU359C, LEU45F, LYS150F, LYS308C, LYS314C, LYS315C, LYS319C, LYS332C, LYS338C, LYS342C, LYS343C, LYS346C, LYS350C, LYS40F, LYS53F, LYS66F, LYS70F, PHE153F, PHE334C, PHE355C, PRO162F, PRO317C, PRO329C, PRO351C, SER142F, SER164F, SER180F, SER341C, SER74F, THR143F, THR310C, THR347C, THR349C, THR356C, THR358C, THR57F, TYR141F, TYR149F, TYR330C, TYR51F, TYR55F, TYR75F, TYR76F, VAL148F, VAL161F, VAL312C, VAL323C, VAL333C, VAL354C
• C-L: ALA29L, ALA49C, ALA51C, ARG107C, ARG21L, ARG47C, ASN110C, GLN19L, GLN28L, GLN48C, GLU20L, GLU54C, LYS104C, LYS108C, LYS23L, PHE26L, PRO102C, THR105C, TRP106C, TRP109C, TRP18L, TYR50C, VAL22L, VAL24L
• C-N: ALA49C, ARG107C, ARG201N, ARG203N, ARG47C, ASN110C, ASN45C, LEU197N, LEU199N, LYS104C, LYS108C, LYS112C, LYS118C, LYS204N, LYS44C, LYS46C, SER41C, THR105C, TRP106C, TRP109C, TRP200N, TYR202N, VAL111C, VAL113C, VAL42C
• C-Q: ALA103Q, ALA108Q, ALA127C, ALA128Q, ALA131Q, ALA28C, ALA298C, ALA302C, ALA305C, ALA37Q, ALA42Q, ARG105Q, ARG111Q, ARG130Q, ARG288C, ARG300C, ARG31C, ARG38Q, ARG39Q, ASN23Q, ASN291C, ASN45Q, ASP125Q, ASP22Q, ASP285C, ASP33C, ASP41Q, GLN126Q, GLN135Q, GLN296C, GLU294C, GLY134Q, GLY303C, GLY85Q, HIS279C, HIS36C, ILE122Q, ILE280C, ILE281C, ILE289C, ILE290C, ILE295C, ILE299C, ILE30C, ILE34C, LEU104Q, LEU124Q, LEU127Q, LEU244C, LEU26Q, LEU28Q, LEU29Q, LEU32Q, LEU36Q, LEU52Q, LYS133Q, LYS27Q, LYS31Q, LYS46Q, PHE106Q, PHE35Q, PRO132Q, PRO277C, PRO29C, PRO301C, PRO32C, SER124C, SER21Q, SER278C, SER27C, SER282C, SER284C, SER292C, SER293C, SER297C, THR107Q, THR123Q, THR275C, THR283C, THR287C, THR34Q, THR37C, THR40Q, THR86Q, TYR120C, TYR25Q, TYR33Q, VAL129Q, VAL24Q, VAL286C, VAL30Q
• C-S: ALA127S, ALA67S, ARG26S, ARG28S, ARG99S, ASN62S, ASN65S, ASP362C, GLN63S, GLN8S, GLU357C, GLU6S, HIS361C, HIS68S, ILE10S, ILE61S, ILE64S, LEU24S, LEU359C, LYS125S, LYS360C, MET27S, PHE355C, SER60S, THR356C, THR358C, TYR7S, VAL126S, VAL354C
• C-T: ALA152T, ALA352C, ALA353C, ASN146T, ASP362C, GLN149T, GLU144T, GLU357C, GLY145T, HIS361C, LEU151T, LEU359C, PHE355C, PRO148T, THR143T, THR150T, THR358C, VAL147T, VAL354C
• C-Y: ALA2Y, ARG12Y, ARG13Y, ARG16Y, ARG195C, ARG197C, ARG198C, ARG220C, ASN196C, ASN221C, ASP11Y, GLN4Y, GLY192C, LEU187C, LYS14Y, LYS193C, LYS217C, LYS3Y, SER10Y, SER9Y, TRP199C, TYR194C
• C-a: ARG12a, ARG4a, HIS36C, LYS44C, PHE100C, PHE5a, PRO2a, THR40C
• C-e: ARG141C, LYS80e
• C-j: ALA51j, ALA56C, ALA62C, ARG55j, ARG56j, ARG84C, GLN59C, HIS58C, LYS52j, LYS55C, SER61C, THR60C, VAL77C
• D-I: ALA218I, ALA219I, ALA283D, ALA287D, ALA288D, ALA291D, ALA292D, ALA294D, ARG211I, ARG282D, ARG285D, ASN208I, ASN209I, GLN296D, GLU207I, GLY204I, GLY295D, ILE210I, ILE290D, LEU200I, LEU206I, LEU293D, LYS202I, LYS289D, PHE217I, PRO214I, SER205I, TYR216I, VAL286D
• D-J: ALA2D, ALA98J, ARG137J, ARG141J, ARG143J, ARG152D, ARG22D, ARG23D, ARG24D, ARG54D, ASN150J, ASN57D, ASP29D, CYS144J, GLN151D, GLN4D, GLU25D, GLY100J, GLY146J, GLY149D, GLY26D, ILE148D, ILE61D, LEU150D, LYS142J, LYS145J, LYS153J, LYS156J, LYS27D, PHE3D, PHE55D, SER97J, THR154J, THR155J, THR28D, THR56D, THR99J
• D-T: ALA11D, ALA24T, ALA42D, ARG15D, ARG17T, ARG20T, ARG23D, ARG33D, ARG35D, ARG50D, ARG92T, ASN45D, ASN45T, ASN66T, ASP18T, ASP29D, ASP38T, ASP72D, GLN17D, GLN32D, GLN39D, GLU94T, GLY23T, GLY71D, HIS22T, HIS26T, HIS40D, HIS98T, ILE48T, ILE69D, ILE96T, LEU27T, LEU31T, LEU36D, LYS21T, LYS32T, LYS34D, LYS35T, LYS41D, LYS43D, LYS48D, LYS69T, PHE16D, PHE19T, PHE20D, PRO19D, PRO47D, SER13D, SER14D, SER28T, SER47T, SER66D, SER67D, SER70T, SER71T, THR18D, THR28D, THR29T, THR38D, THR46D, THR68D, THR68T, THR70D, TYR12D, TYR30D, TYR30T, TYR31D, TYR34T, TYR44D, VAL25T, VAL33T, VAL36T, VAL37D, VAL64T, VAL67T, VAL72T, VAL93T
• D-b: ALA42D, ASP36b, HIS40D, LYS38b, LYS43D, PHE39b, TYR44D
• E-M: ALA110M, ALA111M, ALA161E, ARG108M, ARG109M, ARG117M, ARG51E, ASP114M, ASP169E, GLN119M, GLN126M, GLN157E, GLU107M, GLU116M, ILE41E, ILE85E, LEU112M, LEU123M, LEU154E, LEU155E, LEU159E, LEU165E, LEU174E, LYS156E, LYS166E, LYS170E, LYS175E, LYS90E, MET121M, MET173E, PHE115M, PHE118M, PHE163E, PHE176E, PRO153E, PRO171E, SER160E, SER162E, SER164E, SER88E, THR113M, THR152E, THR87E, THR89E, TYR158E, VAL120M, VAL122M, VAL39E
• E-O: ASN167E, GLN193O, LEU154E, PHE197O, VAL3O
• E-P: ALA178P, ARG171P, ARG173P, ARG175P, ARG181P, ARG46E, ARG48E, ARG77E, GLU129E, GLY174P, GLY45E, ILE130E, ILE182P, LYS108E, SER170P
• E-S: LYS161S, LYS170E
• E-e: ALA16E, ALA3E, ALA6E, ALA77e, ALA97e, ASN78e, ASN99e, ASP14E, ASP81e, GLN4E, GLU13E, GLU83e, GLU95e, HIS71e, HIS88e, HIS98e, ILE100e, ILE96e, LEU18E, LEU4e, LEU66e, LEU75e, LEU85e, LYS5E, LYS72e, LYS80e, LYS8E, LYS90e, MET87e, PHE74e, PRO11E, PRO5e, PRO7E, SER12E, SER2E, SER3e, THR73e, THR84e, THR86e, THR89e, THR91e, TRP9E, TYR10E, TYR92e, VAL15E, VAL76e
• E-f: ALA161E, ALA2f, ALA32E, ALA36f, ALA41f, ALA44E, ALA81E, ALA86E, ARG31E, ARG48E, ARG48f, ARG6f, ARG82E, ASN106f, ASN167E, ASN80E, ASP169E, ASP40f, GLN39f, GLN42f, GLU33f, GLU3f, GLY168E, GLY34f, GLY45E, GLY46f, GLY49E, HIS172E, HIS5f, ILE100f, ILE107f, ILE32f, ILE41E, ILE85E, LEU102f, LEU165E, LEU174E, LEU34E, LEU40E, LEU42E, LEU43E, LEU7f, LYS10f, LYS166E, LYS170E, LYS175E, LYS47f, LYS50E, MET173E, PHE101f, PHE163E, PHE176E, PHE43f, PHE47E, PRO104f, PRO171E, SER105f, SER162E, SER164E, SER33E, SER4f, SER88E, THR37f, THR87E, TRP68f, TYR103f, TYR44f, TYR83E, TYR8f, VAL35f, VAL84E, VAL9f
• F-Q: ARG100F, ARG107F, ARG110F, ARG88F, ASN93F, ASP4Q, GLN104F, GLN9Q, GLY2Q, GLY91F, HIS5Q, ILE111F, ILE3Q, ILE92F, ILE95F, LEU103F, LEU105F, LEU108F, LYS101F, LYS206F, PRO97F, SER113F, SER7Q, THR109F, THR6Q
• F-S: ALA2S, ALA31S, ALA37S, ALA54S, ARG119S, ARG12S, ARG232F, ARG26S, ARG40S, ASN231F, ASN33S, ASN62S, GLN225F, GLN80F, GLN8S, GLU233F, GLU234F, GLU34S, GLU57S, GLU78F, GLY11S, GLY226F, GLY227F, GLY230F, GLY56S, GLY73F, HIS222F, HIS81F, ILE10S, ILE224F, ILE236F, ILE36S, ILE58S, ILE61S, LEU124F, LEU14S, LEU24S, LYS121F, LYS128F, LYS221F, LYS38S, LYS53S, LYS5S, LYS66F, LYS70F, MET1S, PHE118S, PHE223F, PHE235F, SER32S, SER39S, SER60S, SER74F, TYR138F, TYR75F, TYR76F, TYR7S, VAL35S, VAL59S, VAL77F
• F-T: ALA122F, ALA133T, ALA65F, ALA69F, ALA72F, ALA79F, ARG136T, ARG139T, ASN146T, ASP68F, GLN131T, GLN134T, GLN197F, GLN80F, GLU137T, GLU144T, GLU78F, GLY73F, HIS81F, ILE140T, ILE62F, LEU124F, LEU83F, LYS118F, LYS121F, LYS129T, LYS196F, LYS66F, LYS70F, LYS82F, PRO132T, PRO135T, PRO148T, SER138T, SER142T, SER74F, THR120F, THR123F, THR143T, TYR75F, TYR76F, VAL119F, VAL141T, VAL147T, VAL191F, VAL77F
• F-b: ARG100F, ARG14b, HIS17b, LYS101F, PRO97F, THR13b
• G-N: ALA141G, ALA168G, ALA3N, ALA40N, ALA76G, ARG20N, ARG24N, ARG26N, ARG31N, ARG41N, ARG44N, ARG49N, ARG57G, ARG60G, ARG63N, ARG68G, ASN137G, ASN34N, ASP158G, ASP17N, ASP46N, GLN11N, GLN23N, GLN32N, GLN59G, GLN61G, GLU144G, GLU161G, GLU29N, GLU54G, GLU8N, GLY135G, GLY234G, GLY235G, GLY236G, GLY2N, HIS138G, ILE143G, ILE160G, ILE64G, ILE67G, ILE75G, LEU10N, LEU136G, LEU142G, LEU162G, LEU166G, LEU169G, LEU19N, LEU22N, LEU65G, LEU69G, LEU7N, LYS172G, LYS183G, LYS193G, LYS230G, LYS33N, LYS5N, LYS62G, LYS63G, LYS70G, MET173G, PHE165G, PHE21N, PRO159G, PRO42N, PRO45N, PRO72G, PRO73G, SER16N, SER66G, THR194G, THR43N, THR74G, TRP233G, TRP28N, TYR30N, TYR4N, TYR55G, TYR6N, VAL139G, VAL140G, VAL157G, VAL163G, VAL164G, VAL18N, VAL197G, VAL25N, VAL27N, VAL58G, VAL71G
• G-X: ALA30X, ARG27X, ARG33X, ARG44G, ARG48G, ARG60G, ASN45G, LEU24X, LEU34X, LEU46G, LYS25X, LYS43G, LYS51G, PHE32X, PRO35X, PRO42G, PRO53G, SER29X, SER47G, THR28X, THR31X, TRP52G, TYR49G, TYR55G, VAL26X, VAL50G, VAL56G
• G-Z: ALA124Z, ALA63Z, ARG121Z, ARG65Z, ASN24G, GLN123Z, GLN128Z, GLU119Z, GLU120Z, GLY125Z, HIS122Z, HIS28G, HIS57Z, LEU26G, LEU51Z, LYS52Z, LYS55Z, LYS56Z, PHE131Z, PRO25G, PRO50Z, SER132Z, SER29G, THR27G, THR30G, THR54Z, THR66Z, TRP129Z, VAL53Z, VAL62Z
• G-g: GLN38G, LYS103g, LYS99g
• G-i: ALA141G, ALA168G, ALA48i, ARG36i, ARG55i, ASN137G, ASN145G, CYS170G, GLN77G, GLU144G, GLU46i, GLY49i, ILE143G, ILE47i, ILE75G, LEU166G, LEU169G, LEU43i, LYS146G, LYS171G, LYS172G, LYS230G, MET173G, PHE165G, PHE39i, PRO167G, PRO72G, PRO73G, SER42i, THR74G, TRP233G, TYR226G, VAL140G, VAL163G, VAL164G, VAL40i, VAL44i
• H-M: ALA56H, ALA9M, ARG23H, ASN11M, ASN49H, ASN50H, ASN59H, ASP40M, ASP42H, ASP4M, GLN41M, GLN51H, GLN5H, GLY15H, GLY60H, HIS58H, ILE10H, ILE20H, ILE24H, ILE38M, ILE4H, ILE53H, ILE6M, ILE79H, LEU14M, LEU52H, LYS21H, LYS26H, LYS2H, LYS42M, LYS47H, LYS54H, LYS8M, MET1H, PHE45H, PRO13H, SER10M, SER19H, SER22H, SER5M, THR17H, THR3M, THR44H, THR46H, TRP12M, TYR3H, VAL12H, VAL15M, VAL16H, VAL18H, VAL25H, VAL27H, VAL28H, VAL43H, VAL48H, VAL55H, VAL57H, VAL7M
• H-O: ARG133O, ARG23H, ASN59H, ASP42H, GLY132O, GLY60H, GLY61H, HIS40H, HIS64H, ILE41H, LYS130O, LYS134O, LYS2H, PRO131O, TYR135O
• H-S: ALA56H, ARG113S, ARG137S, ASN59H, ASP42H, GLN138S, GLN142S, GLN5H, GLY60H, HIS154S, HIS58H, HIS64H, ILE4H, LEU144S, LEU148S, LEU152S, LYS141S, LYS149S, LYS2H, MET1H, PHE143S, PHE150S, PRO151S, PRO153S, THR145S, THR44H, THR6H, TYR139S, TYR3H, VAL140S, VAL57H
• H-m: ALA159H, ALA84m, ALA86m, ALA95H, ARG102m, ARG122m, ARG166H, ARG173H, ARG91H, ASN90m, ASP142H, ASP171H, ASP177H, ASP92m, CYS165H, CYS91m, GLN162H, GLN163H, GLU143H, GLU79m, GLY178H, HIS183H, HIS96H, ILE172H, ILE179H, ILE77m, ILE78m, LEU127m, LEU176H, LEU82m, LEU85m, LYS124m, LYS125m, LYS126m, LYS128m, LYS141H, LYS170H, LYS174H, LYS184H, LYS83m, LYS88m, LYS89H, LYS93m, MET90H, PHE117H, PHE175H, SER182H, SER81m, SER87m, TYR180H, TYR88H, TYR89m, TYR92H, TYR94H, VAL140H, VAL167H, VAL181H, VAL93H
• I-S: ARG84S, ASN55I, GLN162I, GLY86S, HIS88S, ILE131I, LYS164I, SER83S, SER85S, THR87S
• I-T: ARG12T, ARG21I, ARG90I, ASN175I, ASP177I, CYS49I, GLN133I, GLU157T, GLY132I, GLY172I, HIS51I, ILE134I, ILE160T, ILE165I, ILE166I, LEU167I, LYS164I, LYS169I, LYS170I, PHE159T, SER168I, THR158T, THR174I, TYR156T, TYR22I, VAL50I, VAL53I
• I-b: ARG116I, GLY117I, LYS3b, MET115I
• J-o: GLY101o, LYS49J
• L-N: ALA29L, ARG100L, ARG193N, ARG201N, ARG203N, ARG21L, ARG35L, ASN195N, ASP27L, GLN194N, GLN19L, GLN28L, GLU20L, GLY30L, HIS13L, HIS17L, HIS25L, LEU197N, LEU199N, LYS16L, LYS176N, LYS192N, LYS204N, LYS23L, LYS31L, LYS32L, PHE14L, PHE26L, SER198N, THR196N, TRP18L, TRP191N, TRP200N, TYR202N, VAL22L, VAL24L
• L-Q: ALA162Q, ARG164Q, ASN12L, ASN6L, GLU173Q, GLY154Q, GLY156Q, HIS152Q, ILE165Q, ILE9L, LEU10L, LEU166Q, LEU7L, LYS11L, LYS161Q, LYS171Q, LYS5L, MET155Q, PHE153Q, PHE172Q, PRO163Q, PRO8L, SER167Q
• L-Y: LEU6Y, VAL33L
• L-a: ALA106a, ALA107a, ALA127a, ALA134a, ALA141a, ALA149a, ALA151L, ALA156L, ALA158L, ALA166L, ALA173L, ALA2L, ALA35a, ALA66a, ALA99a, ARG128a, ARG139a, ARG157L, ARG15L, ARG168L, ARG171L, ARG174L, ARG32a, ARG42a, ARG59L, ARG67L, ASN162L, ASN44a, ASN66L, ASN6L, ASP103a, ASP153L, ASP161L, GLN149L, GLN160L, GLN38a, GLN64a, GLN65a, GLN89a, GLU135a, GLU136a, GLU146a, GLU155L, GLU164L, GLU97a, GLY108a, GLY142a, GLY143a, GLY163L, GLY30a, GLY31a, GLY33a, GLY36a, GLY37a, HIS28a, HIS39a, HIS40a, HIS41a, HIS49a, HIS67a, ILE102a, ILE112a, ILE124a, ILE138a, ILE148a, ILE3L, ILE43a, ILE82a, ILE9L, LEU105a, LEU10L, LEU113a, LEU133a, LEU147a, LEU170L, LEU7L, LYS111a, LYS11L, LYS126a, LYS132a, LYS47a, LYS5L, LYS64L, LYS68L, LYS70a, LYS86a, LYS96a, MET34a, MET45a, PHE129a, PHE167L, PHE53a, PHE68a, PRO100a, PRO122a, PRO29a, PRO50a, PRO61L, PRO71a, PRO83a, PRO8L, SER131a, SER165L, SER4L, SER95a, THR104a, THR152L, THR169L, THR62L, THR98a, TRP69a, TYR109a, TYR48a, TYR52a, TYR65L, TYR90a, VAL101a, VAL121a, VAL123a, VAL125a, VAL130a, VAL144a, VAL145a, VAL154L, VAL159L, VAL63L
• L-h: ALA110h, ALA117h, ALA120h, ALA132L, ALA135L, ALA141L, ALA142L, ALA143L, ALA47L, ALA87L, ALA88L, ALA90L, ARG114h, ARG128L, ARG42L, ARG49L, ARG91L, ASN129L, ASP52L, GLN108h, GLN113h, GLN120L, GLN137L, GLU118L, GLU134L, GLU136L, GLY130L, GLY94L, ILE109h, ILE118h, ILE123L, ILE124L, ILE46L, ILE93L, ILE95L, LEU139L, LEU51L, LEU53L, LEU54L, LYS106h, LYS107h, LYS115h, LYS119h, LYS122L, LYS131L, PHE111h, PHE126L, PHE145L, PRO112h, PRO127L, PRO133L, PRO48L, PRO50L, SER121L, SER140L, THR144L, THR86L, THR92L, TYR116h, TYR119L, TYR89L, VAL125L, VAL138L
• L-i: ALA151L, ALA166L, ALA173L, ALA23i, ALA78L, ALA82L, ALA8i, ARG100L, ARG101L, ARG104L, ARG168L, ARG171L, ARG174L, ARG180L, ARG59L, ARG67L, ASN103L, ASN105L, ASN12i, ASN66L, ASP110L, GLN102L, GLN106L, GLU107L, GLU176L, GLU184L, GLU79L, GLY10i, GLY14i, GLY181L, HIS99L, ILE108L, ILE7i, ILE9i, LEU11i, LEU170L, LEU172L, LEU77L, LYS13i, LYS15i, LYS16i, LYS177L, LYS178L, LYS25i, LYS4i, LYS81L, MET20i, PHE109L, PHE167L, PHE179L, PRO22i, PRO24i, SER175L, SER19i, THR152L, THR169L, THR18i, THR21i, THR5i, THR76L, TYR28i, VAL113L, VAL17i, VAL63L
• M-O: ALA104M, ALA110M, ALA111M, ALA134M, ALA136M, ALA138M, ALA181O, ALA183O, ALA185O, ALA186O, ALA191O, ALA195O, ALA196O, ARG106M, ARG108M, ARG109M, ARG117M, ARG124M, ARG128M, ASN182O, ASP189O, GLN105M, GLN119M, GLN126M, GLN193O, GLU107M, GLU116M, GLU187O, GLY198O, LEU112M, LEU123M, LEU135M, LEU194O, LEU197O, LYS125M, LYS127M, LYS132M, LYS133M, LYS137M, LYS176O, LYS177O, LYS192O, MET121M, PHE115M, PHE118M, PHE174O, PHE197O, SER179O, SER180O, SER188O, THR113M, THR130M, THR175O, THR184O, TYR129M, TYR199O, VAL120M, VAL122M, VAL131M, VAL178O, VAL190O
• M-S: ALA101S, ALA102S, ALA57M, ARG13M, ARG155S, ARG19M, ARG55M, ARG74M, ARG77M, ARG95S, ASN11M, ASN74S, ASP147S, ASP40M, ASP47M, ASP96S, GLN142S, GLN157S, GLN41M, GLN56M, GLU104S, GLU16M, GLU37M, GLY61M, GLY75M, HIS154S, HIS68S, ILE35M, ILE38M, ILE39M, ILE46M, ILE58M, ILE94S, LEU144S, LEU148S, LEU14M, LEU152S, LEU22M, LEU45M, LEU60M, LEU65M, LYS146S, LYS149S, LYS158S, LYS24M, LYS25M, LYS42M, LYS43M, LYS71S, LYS73S, PHE143S, PHE150S, PHE171S, PRO151S, PRO153S, PRO54M, PRO67M, PRO69S, SER10M, SER98S, THR105S, THR132S, THR145S, THR170S, THR66M, THR69M, THR70S, THR78M, TRP12M, TRP99M, TYR139S, TYR172S, VAL140S, VAL156S, VAL15M, VAL17M, VAL21M, VAL36M, VAL44M, VAL63M, VAL64M, VAL72S, VAL97S
• M-f: ALA2f, MET121M
• N-a: ASN181N, HIS178N, HIS62a
• N-h: ALA146N, ALA87h, ALA91h, ALA97h, ARG114N, ARG143N, ARG144N, ARG147N, ARG86h, ARG89h, ARG90h, ASN149N, ASP145N, ASP153N, CYS152N, GLN104h, GLN138N, GLN99h, GLU102h, GLU96h, HIS139N, ILE142N, ILE151N, LEU88h, LEU92h, LYS103h, LYS140N, LYS157N, LYS74h, LYS94h, PHE95h, PRO137N, PRO154N, SER98h, THR101h, THR93h, TRP150N, TYR148N, VAL100h
• N-i: ALA3N, ALA48i, ARG12N, ARG20N, ARG36i, ARG41i, ARG45i, ARG55i, ARG56i, ARG76i, ASP17N, GLN11N, GLN15N, GLU54i, GLU89i, GLU8N, GLU9N, GLY2N, GLY49i, ILE47i, LEU10N, LEU19N, LEU43i, LEU50i, LEU7N, LYS13N, LYS14N, LYS38i, LYS5N, LYS86i, PHE39i, PRO52i, SER16N, SER34i, SER42i, SER51i, THR37i, TYR4N, TYR53i, TYR6N, VAL18N, VAL40i, VAL44i
• N-j: ARG108N, LYS43j
• N-o: ARG73N, ASN70N, ASN86N, ASN90N, GLN53o, GLN87N, GLU91N, GLY49o, GLY51o, GLY52o, GLY88N, LEU92N, LYS83N, LYS93N, PHE50o, PRO84N, SER48o, THR54o, THR80N, THR85N, VAL89N
• O-S: ALA11O, ALA123O, ARG117O, ARG125O, ARG128O, ARG155S, ARG167S, ARG37O, ASN42O, ASP10O, ASP13O, GLN122O, GLN157S, GLN26O, GLN31O, GLN4O, GLU40O, GLY11O, GLY13O, HIS14O, HIS154S, ILE108O, ILE23O, ILE33O, ILE9O, LEU124O, LEU127O, LEU129O, LEU15O, LEU19O, LEU27O, LEU41O, LYS116O, LYS12O, LYS130O, LYS158S, LYS161S, LYS166S, LYS25O, LYS32O, PHE163S, PHE171S, PRO121O, PRO131O, PRO153S, PRO168S, SER159S, SER164S, SER169S, THR160S, THR162S, THR170S, TYR165S, VAL118O, VAL119O, VAL120O, VAL126O, VAL156S, VAL22O, VAL23O, VAL35O, VAL36O, VAL3O, VAL6O, VAL7O, VAL8O
• O-V: GLY8V, PHE7O, THR9V, TYR8O
• O-f: ALA91f, ALA93O, ALA96f, ALA97O, ALA98O, ARG101O, ARG18f, ARG94O, ASN29O, GLN26O, GLN31O, GLN4O, GLU33f, GLY30O, GLY34f, GLY95f, HIS13f, LEU14f, LEU27O, LEU28O, LYS10f, LYS12f, LYS25O, LYS31f, LYS32O, LYS92f, PHE94f, PRO5O, SER15f, SER89O, SER97f, THR93f, VAL3O, VAL80f
• O-m: ARG113m, ARG49O
• P-d: ASP47d, ASP53P, GLU49P, LYS86d
• P-f: ARG167P, ARG171P, ARG173P, ARG175P, ARG60f, GLN172P, GLU58f, GLY61f, ILE176P, ILE64f, LEU168P, LYS164P, LYS63f, SER170P, SER62f, THR169P, VAL165P, VAL166P, VAL59f
• P-j: GLY134P, HIS133P, THR5j
• Q-a: ALA112Q, ALA162Q, ALA175Q, ALA91Q, ARG117a, ARG164Q, ARG170Q, ARG174Q, ARG176Q, ARG178Q, ARG179Q, ARG42a, ARG59a, ARG69Q, ARG87a, ARG92Q, ASN74a, ASP46a, ASP76a, ASP85a, ASP88a, ASP89Q, ASP90Q, GLN38a, GLN89a, GLU173Q, GLU84a, GLU95Q, GLY109Q, GLY116a, GLY154Q, GLY156Q, GLY160Q, GLY169Q, GLY177Q, GLY183Q, GLY37a, GLY51a, GLY54a, GLY57a, HIS152Q, HIS158Q, HIS49a, ILE118a, ILE165Q, ILE43a, ILE82a, ILE93Q, LEU166Q, LEU75a, LEU78a, LEU91a, LYS113Q, LYS115a, LYS116Q, LYS159Q, LYS161Q, LYS171Q, LYS182Q, LYS185Q, LYS47a, LYS55a, LYS63a, LYS77a, LYS92a, MET155Q, MET45a, MET58a, PHE172Q, PHE184Q, PHE53a, PHE61a, PHE94Q, PRO119a, PRO157Q, PRO163Q, PRO50a, SER181Q, THR80a, TRP79a, TYR48a, TYR52a, TYR60a, VAL121a, VAL186Q, VAL56a
• Q-b: ARG18b, ASN19b, LYS8Q
• R-X: ASN39R, LYS74X, SER37R
• S-T: ALA152T, ALA54S, ARG12S, ARG136T, ARG139T, ARG13S, ARG26S, ARG28S, ARG40S, ARG80S, ASN146T, ASN89S, ASP82S, GLN149T, GLN8S, GLU137T, GLU144T, GLU157T, GLU21S, GLU57S, GLY11S, GLY145T, GLY56S, GLY86S, HIS122S, HIS49S, HIS88S, ILE10S, ILE121S, ILE123S, ILE140T, ILE29S, ILE58S, LEU124S, LEU14S, LEU151T, LEU24S, LEU45S, LEU48S, LYS125S, LYS23S, LYS47S, LYS53S, MET27S, MET90S, PHE159T, PHE25S, PHE44S, PRO148T, PRO153T, PRO155T, PRO15S, PRO22S, SER138T, SER142T, SER55S, SER60S, SER85S, THR143T, THR150T, THR158T, THR87S, TRP42S, TRP78S, TYR156T, TYR41S, TYR43S, TYR81S, VAL126S, VAL141T, VAL147T, VAL154T, VAL51S, VAL59S, VAL79S, VAL9S
• S-f: ALA36f, GLY34f, LYS161S, LYS31f, THR160S, THR162S
• T-b: ALA16b, ARG18b, ARG40b, ARG83T, ARG88T, ASN19b, ASN66T, ASN6b, ASN77T, ASN82T, ASN90T, ASP36b, GLN12b, GLU86T, GLY20b, GLY34b, GLY73T, GLY81T, HIS17b, HIS7b, ILE21b, ILE75T, ILE76T, LEU32b, LEU85T, LYS15b, LYS22b, LYS23b, LYS25b, LYS33b, LYS38b, LYS3T, LYS69T, LYS78T, LYS87T, MET79T, PHE39b, PRO24b, PRO30b, PRO37b, SER31b, THR13b, THR26b, THR68T, TYR27b, TYR65T, TYR84T, VAL35b, VAL36T, VAL63T, VAL64T, VAL67T, VAL80T
• V-W: ALA37W, ALA82V, ARG17W, ARG23W, ARG30W, ARG80V, ARG86V, ARG87V, ASP25W, ASP89V, ASP97V, GLN81V, GLU4W, GLU96V, GLY116V, GLY119V, GLY134V, GLY16W, GLY18W, GLY24W, GLY90V, ILE13W, ILE28W, LEU20W, LEU93V, LYS120V, LYS27W, LYS41W, PHE21W, PHE29W, PHE31W, PHE40W, PHE92V, PHE95V, PRO117V, PRO15W, SER26W, SER34W, SER38W, SER84V, THR115V, THR19W, TRP85V, TYR94V, VAL118V, VAL135V, VAL136V, VAL137V, VAL22W, VAL91V
• X-h: ALA136X, ALA29h, ALA47X, ALA50X, ALA52h, ALA65h, ARG138X, ARG48h, ARG56X, ARG63h, ARG67h, ARG81h, ASN137X, ASN55X, ASN59h, ASP23h, ASP58X, ASP79h, GLN34h, GLN61h, GLN62h, GLN65X, GLN76h, GLN85X, GLU101X, GLU27h, GLU30h, GLU60h, GLU64X, GLU64h, GLY140X, HIS53X, ILE139X, ILE142X, ILE44h, ILE51h, ILE58h, ILE63X, ILE67X, LEU102X, LEU21h, LEU24h, LEU28h, LEU31h, LEU36h, LEU55h, LEU57X, LEU69h, LEU80h, LYS25h, LYS26h, LYS32h, LYS35h, LYS45X, LYS49X, LYS61X, LYS73h, LYS74h, LYS78h, PHE84X, PRO44X, PRO52X, PRO66X, PRO77h, SER37h, SER48X, SER59X, SER69X, THR56h, THR68X, TYR103X, TYR141X, TYR46X, TYR54X, TYR60X, TYR70h, TYR75h, VAL22h, VAL33h, VAL51X, VAL66h
• X-l: ALA14l, ALA16l, ARG115X, ASN117X, GLN11l, GLY118X, LEU113X, LYS10l, LYS120X, LYS15l, LYS17l, LYS18l, LYS5l, MET13l, MET88X, PHE7l, PRO116X, THR119X, VAL114X
• Y-j: ALA117Y, ALA88j, ARG121Y, ASP114Y, LEU118Y, LYS113Y
• Y-l: ARG27Y, ARG30l, ASN32l, ASN33l, ASN98Y, LEU76Y, LYS77Y, PHE20Y, PHE78Y, THR31l, TYR74Y
• Z-c: ALA11Z, ALA2Z, ALA60c, ARG15Z, ARG35c, ARG84Z, ASN76Z, ASN78Z, ASP30Z, GLN36c, GLU31Z, GLU55c, GLY37c, GLY39Z, HIS40Z, HIS79Z, ILE25Z, LEU34c, LEU51c, LEU56c, LEU5Z, LEU62c, LEU80Z, LEU81Z, LYS28c, LYS32c, LYS38c, LYS3Z, LYS64c, LYS9Z, MET61c, PHE38Z, PHE4Z, PRO82Z, SER33c, SER39c, SER54c, SER63c, THR65c, THR83Z, TRP129Z, TYR27c, TYR58c, TYR59c, TYR77Z, TYR85Z, VAL10Z, VAL12Z, VAL14Z, VAL31c
• Z-g: ALA11Z, ALA19Z, ALA75g, ALA82g, ALA92g, ARG135Z, ARG15Z, ARG17Z, ARG74g, ARG80g, ARG84Z, ARG88g, ARG91g, ASN78Z, ASN83g, CYS81g, CYS84g, GLN52g, GLN98g, GLU87g, GLU96g, GLU97g, GLY16Z, GLY20Z, HIS79Z, ILE100g, ILE89g, ILE90g, ILE95g, LEU134Z, LEU80Z, LEU81Z, LEU94g, LYS133Z, LYS21Z, LYS22Z, LYS86g, PHE136Z, PHE93g, PRO82Z, SER73g, THR83Z, TRP129Z, TYR18Z, TYR76g, TYR85Z, VAL101g, VAL104g, VAL10Z, VAL12Z, VAL13Z, VAL14Z, VAL72g, VAL85g
• a-e: ARG12a, ARG19e, ARG21a, ARG33e, ARG43e, ASP39e, GLN35e, GLY13a, GLY37e, HIS11a, HIS14a, ILE38e, LYS34e, LYS36e, SER16a, VAL15a
• a-i: ALA127a, ALA149a, ALA8i, ARG128a, ASP103a, GLU146a, GLY10i, GLY110a, GLY14i, GLY6i, HIS67a, ILE148a, ILE7i, ILE9i, LEU105a, LEU147a, LYS126a, LYS13i, LYS15i, LYS16i, LYS4i, LYS70a, PHE129a, THR5i
• a-o: ARG41o, ARG42o, ARG59a, GLN38o, GLY39o, LYS55a, PHE61a
• c-g: ALA92g, ARG52c, ARG88g, ARG91g, GLN98g, GLU55c, GLU57c, GLU87g, GLU97g, ILE100g, ILE89g, ILE90g, ILE95g, LEU51c, LEU56c, LEU62c, LEU94g, LYS28c, LYS53c, LYS86g, MET61c, PHE93g, PRO49c, SER54c, TYR27c, TYR58c, TYR59c, TYR69c, VAL101g, VAL50c
• c-p: ARG86c, ASN75c, GLY43p, LYS44p
• e-f: ARG21f, ARG47e, LYS20f, SER19f, VAL22f
• g-l: ALA2l, ALA3l, ARG10g, ASN11g, GLN4l, LYS5l
• h-j: ALA82h, ARG10h, ARG67h, ARG73j, ARG81h, ARG86h, ARG89h, GLN79j, GLY77j, GLY81j, LEU80h, LEU88h, LYS83h, LYS84h, LYS85j, PHE74j, PHE78j, THR80j, THR85h, TYR66j, TYR7h, VAL70j
• j-l: ALA2l, ARG11j, ARG21j, ARG24j, ARG25j, ARG8l, ASN20j, ASN50l, CYS19j, GLY23j, HIS16j, ILE51l, ILE9l, LEU18j, LYS12l, LYS14j, LYS48l, MET49l, SER6l, THR17j, TYR39j