3TYG

crystal structure of broad and potent hiv-1 neutralizing antibody pgt128 in complex with a glycosylated engineered gp120 outer domain with miniv3 (eodmv3)

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-H
  • Int. Res.: 37
  • Norm. En. per Res.: -3.1568
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-H	-16.3932	-0.7691	-99.6393	-116.8016	37	7	1	3635	0	7	7
L-H	-59.8043	-35.4481	-439.65	-534.9024	181	18	13	17514	3	19	19

Interface residues

• A-H: ALA31H, ALA52H, ARG100H, ARG101A, ARG107A, ARG116A, ASN103A, ASN104A, ASN121A, ASN33H, ASP100H, ASP114A, CYS32H, CYS52H, GLN117A, GLU110A, GLU98H, GLY113A, HIS119A, ILE111A, ILE112A, ILE115A, LEU100H, LYS100H, PRO100H, PRO102A, PRO13A, SER52H, THR100A, THR100H, THR106A, TRP100H, TRP52H, TRP56H, TYR100H, TYR52H, VAL99H
• L-H: ALA100H, ALA125H, ALA127L, ALA130L, ALA138H, ALA139H, ALA174L, ALA175L, ALA176H, ALA3L, ALA40L, ALA43L, ALA93H, ARG105H, ARG38H, ARG94H, ASN128L, ASN170L, ASN30L, ASN31L, ASN60H, ASN94L, ASP100H, ASP101H, ASP138L, ASP146H, ASP50L, ASP95L, CYS134L, CYS142H, CYS88L, CYS92H, GLN126L, GLN167L, GLN179H, GLN37L, GLN38L, GLN39H, GLU123L, GLU124L, GLU160L, GLU46H, GLU6H, GLU98H, GLY100L, GLY101L, GLY104H, GLY106H, GLY141H, GLY158L, GLY183H, GLY41L, GLY42H, GLY44H, GLY49H, GLY89L, GLY93L, GLY96H, GLY97H, GLY99L, HIS172H, HIS39L, HIS59H, ILE136L, ILE48L, ILE97L, LEU102H, LEU117L, LEU124H, LEU125L, LEU132L, LEU135L, LEU140H, LEU143H, LEU178H, LEU179L, LEU181L, LEU187H, LEU45H, LEU46L, LEU91L, LYS100H, LYS117H, LYS129L, LYS145H, LYS166L, LYS172L, LYS207L, LYS221H, LYS228H, LYS42L, LYS43H, LYS45L, LYS53L, PHE118L, PHE122H, PHE139L, PHE174H, PHE32L, PHE35H, PHE95H, PHE98L, PRO100H, PRO119L, PRO120L, PRO123H, PRO126H, PRO164L, PRO175H, PRO227H, PRO41H, PRO44L, PRO55L, PRO61H, SER114L, SER120H, SER121L, SER122L, SER127H, SER134H, SER137L, SER165L, SER168L, SER176L, SER177L, SER180H, SER180L, SER181H, SER186H, SER188H, SER189H, SER34L, SER50H, SER56L, SER62H, SER90L, THR116L, THR131L, THR161L, THR162L, THR163L, THR173H, THR192H, THR57H, THR89H, TRP100H, TRP103H, TRP35L, TRP36H, TRP47H, TRP52H, TRP56H, TRP95L, TYR147H, TYR173L, TYR178L, TYR36L, TYR49L, TYR58H, TYR86L, TYR87L, TYR91H, VAL100H, VAL115L, VAL121H, VAL133L, VAL144H, VAL159L, VAL177H, VAL190H, VAL191H, VAL219H, VAL225H, VAL33L, VAL37H, VAL48H, VAL51L, VAL85L, VAL92L, VAL96L, VAL99H