3TW8

gef domain of dennd 1b in complex with rab gtpase rab35

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 130
  • Norm. En. per Res.: -3.4841
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-57.5515	10.664	-406.052	-452.9395	130	8	9	16361	2	29	34
A-C	-38.2349	-2.9267	-134.428	-175.5896	83	8	1	5862	0	14	15
C-D	-44.0417	14.1462	-430.876	-460.7714	134	19	9	17302	2	28	36

Interface residues

• A-B: ALA240A, ALA356A, ALA371A, ALA65B, ARG101B, ARG194A, ARG195A, ARG5A, ARG69B, ARG71B, ARG79B, ARG82A, ASN109B, ASN358A, ASP236A, ASP263A, ASP280A, ASP367A, ASP3A, ASP42A, ASP44B, ASP63B, ASP76A, CYS238A, CYS239A, CYS4A, GLN108B, GLN223A, GLN360A, GLN364A, GLN47A, GLN60B, GLN67B, GLN81A, GLU105B, GLU193A, GLU262A, GLU338A, GLU354A, GLU44A, GLU68B, GLU78A, GLY18B, GLY42B, GLY66B, GLY80B, GLY83B, HIS192A, HIS224A, HIS233A, HIS82B, ILE13B, ILE225A, ILE227A, ILE246A, ILE357A, ILE38B, ILE41B, ILE45A, ILE47B, ILE61B, ILE73B, ILE77A, LEU11B, LEU12B, LEU191A, LEU230A, LEU234A, LEU235A, LEU25B, LEU261A, LEU359A, LEU361A, LEU370A, LEU74A, LEU8B, LYS10B, LYS21B, LYS259A, LYS363A, LYS46B, LYS51A, LYS58B, LYS80A, MET190A, MET242A, MET2A, PHE278A, PHE362A, PHE45B, PHE52A, PHE70B, PHE72A, PRO228A, PRO231A, PRO241A, PRO243A, SER17B, SER189A, SER22B, SER260A, SER36B, SER48A, SER75B, SER79A, THR335A, THR355A, THR39B, THR40B, THR64B, THR72B, THR74B, THR75A, THR76B, THR81B, TRP102B, TRP222A, TRP62B, TYR221A, TYR226A, TYR237A, TYR244A, TYR37B, TYR5B, TYR77B, TYR78B, VAL229A, VAL43B, VAL49A, VAL73A
• A-C: ALA120C, ALA177A, ALA24C, ARG60A, ARG60C, ARG87C, ASN182A, ASN268A, ASN272A, ASN64A, ASN64C, ASP117C, ASP179A, ASP270A, ASP57A, CYS209A, CYS22C, GLN299A, GLN63A, GLN63C, GLN65A, GLN65C, GLN68A, GLN68C, GLU122C, GLU173A, GLU254A, GLU59A, GLU59C, GLY67A, GLY67C, GLY91A, GLY91C, GLY92A, GLY92C, HIS23C, HIS249A, ILE199A, ILE253A, ILE94C, LEU119C, LEU203A, LEU267A, LEU33C, LEU88C, LEU96C, LYS121C, LYS19C, LYS202A, LYS202C, LYS21C, MET183A, PHE175A, SER200A, SER201A, SER204A, SER250A, SER251A, SER62A, SER62C, SER90A, SER90C, THR172A, THR205A, THR271A, THR271C, THR273A, THR89A, THR89C, THR93A, THR93C, TRP34C, TYR174A, VAL176A, VAL178A, VAL180A, VAL269A, VAL31C, VAL58C, VAL61A, VAL61C, VAL66A, VAL66C
• C-D: ALA240C, ALA356C, ALA371C, ALA65D, ARG101D, ARG194C, ARG195C, ARG5C, ARG69D, ARG71D, ARG79D, ARG82C, ASN109D, ASN283C, ASN358C, ASP236C, ASP263C, ASP280C, ASP367C, ASP3C, ASP42C, ASP44D, ASP63D, ASP76C, CYS110D, CYS238C, CYS239C, CYS4C, GLN108D, GLN223C, GLN360C, GLN364C, GLN47C, GLN60D, GLN67D, GLU105D, GLU193C, GLU262C, GLU338C, GLU339C, GLU354C, GLU44C, GLU68D, GLU78C, GLY18D, GLY35D, GLY368C, GLY42D, GLY66D, GLY80D, GLY83D, HIS192C, HIS224C, HIS233C, HIS82D, ILE13D, ILE225C, ILE227C, ILE246C, ILE357C, ILE366C, ILE38D, ILE41D, ILE45C, ILE47D, ILE61D, ILE73D, ILE77C, LEU11D, LEU12D, LEU191C, LEU230C, LEU234C, LEU235C, LEU261C, LEU359C, LEU361C, LEU370C, LEU74C, LEU8D, LYS10D, LYS21D, LYS259C, LYS363C, LYS46D, LYS51C, LYS58D, LYS80C, MET190C, MET242C, MET2C, PHE278C, PHE362C, PHE45D, PHE52C, PHE70D, PHE72C, PRO228C, PRO231C, PRO241C, PRO243C, SER17D, SER189C, SER1C, SER22D, SER260C, SER36D, SER48C, SER75D, SER79C, THR355C, THR39D, THR40D, THR64D, THR72D, THR74D, THR75C, THR76D, THR81D, TRP102D, TRP222C, TRP62D, TYR221C, TYR226C, TYR237C, TYR244C, TYR37D, TYR5D, TYR77D, TYR78D, VAL229C, VAL43D, VAL49C, VAL73C