3THT

crystal structure and rna binding properties of the rrm/alkb domains in human abh8, an enzyme catalyzing trna hypermodification, northeast structural genomics consortium target hr5601b

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 93
  • Norm. En. per Res.: -4.0045
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-84.3314	8.6133	-291.025	-366.7431	98	18	6	11163	0	44	36
A-C	0.0	0.0	-0.0084	-0.0084	2	0	0	8	0	1	1
A-D	-7.1787	-7.4493	-11.5662	-26.1942	24	2	0	634	2	7	10
B-D	0.0	7.9749	-0.2426	7.7323	5	0	0	43	0	1	3
C-D	-88.8612	7.7642	-291.317	-372.4141	93	11	5	10889	0	40	36

Interface residues

• A-B: ALA132A, ALA132B, ALA73A, ALA73B, ALA85A, ALA85B, ARG129A, ARG129B, ARG58A, ARG58B, ARG86A, ARG86B, ARG88A, ARG88B, ASP266A, ASP266B, ASP316A, ASP316B, ASP319A, ASP319B, ASP72A, ASP72B, GLN124A, GLN124B, GLN131A, GLN131B, GLN303A, GLN43A, GLN43B, GLU121A, GLU121B, GLU127A, GLU127B, GLU306A, GLU33A, GLU33B, GLU36A, GLU36B, GLY318A, GLY318B, GLY34A, GLY34B, HIS32A, HIS32B, ILE268A, ILE268B, ILE312A, ILE312B, ILE35A, LEU128A, LEU128B, LEU133A, LEU133B, LEU45A, LEU45B, LEU52A, LEU52B, LEU74A, LEU74B, LEU75A, LEU75B, LYS122A, LYS122B, LYS126A, LYS126B, LYS309A, LYS309B, LYS80A, LYS80B, MET76A, MET76B, PHE84A, PHE84B, PRO130A, PRO130B, PRO77A, PRO77B, PRO78A, PRO78B, SER315A, SER315B, SER44A, SER44B, SER83A, SER83B, THR314A, THR314B, TRP125A, TRP125B, TYR82A, TYR82B, VAL120A, VAL120B, VAL123A, VAL123B, VAL317A, VAL317B, VAL71A
• A-C: LEU70C, LYS324A
• A-D: ARG276D, ARG277D, ARG58A, ASN59A, ASP108A, GLN60A, GLU142D, GLU147D, GLU149D, GLU154D, GLU306D, GLU66A, LEU308D, LEU62A, LEU70A, LYS150D, LYS298A, PRO63A, SER145D, SER146D, SER305D, SER57A, VAL106A, VAL71A
• B-D: ALA304B, ASP319B, GLU147D, GLY318B, SER145D
• C-D: ALA132C, ALA132D, ALA73C, ALA73D, ALA85C, ALA85D, ARG129C, ARG129D, ARG58C, ARG58D, ARG86C, ARG86D, ARG88C, ASP266D, ASP316C, ASP316D, ASP319C, ASP319D, ASP72C, ASP72D, GLN124C, GLN124D, GLN131C, GLN131D, GLN303D, GLN43C, GLN43D, GLU121C, GLU121D, GLU127C, GLU127D, GLU33C, GLU33D, GLU36C, GLU36D, GLY318C, GLY318D, GLY34C, GLY34D, HIS32C, HIS32D, ILE268C, ILE268D, ILE312C, ILE312D, LEU128C, LEU128D, LEU133C, LEU133D, LEU45C, LEU45D, LEU52C, LEU52D, LEU74C, LEU74D, LEU75C, LEU75D, LYS122C, LYS122D, LYS126C, LYS126D, LYS309D, LYS80C, LYS80D, MET76C, MET76D, PHE84C, PHE84D, PRO130C, PRO130D, PRO77C, PRO77D, PRO78C, PRO78D, SER315C, SER315D, SER44C, SER44D, SER83C, SER83D, THR314C, THR314D, TRP125C, TRP125D, TYR82C, TYR82D, VAL120C, VAL120D, VAL123C, VAL123D, VAL317C, VAL317D, VAL71D