3TF2

crystal structure of the cap free human translation initiation factor eif4e

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 88
  • Norm. En. per Res.: -2.6741
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-12.2439	1.6884	-93.2643	-103.8199	46	5	4	3945	0	10	17
A-C	0.0	0.0	-0.0788	-0.0788	7	0	0	23	0	5	6
A-D	-26.3013	-64.0556	-139.454	-229.811	87	8	0	6367	5	39	39
B-C	-37.828	-68.3481	-129.148	-235.3241	88	12	0	6546	5	42	43
B-D	0.0	0.0	-0.064	-0.064	3	0	0	24	0	3	4
C-D	0.0	0.0	-0.0011	-0.0011	2	0	0	3	0	0	0

Interface residues

• A-B: ARG173A, ARG173B, ARG181A, ARG181B, ARG214A, ARG214B, ASN213A, ASN213B, GLU185A, GLU185B, GLY188B, GLY196A, GLY196B, HIS178A, ILE193A, ILE193B, ILE195A, ILE195B, LEU189A, LEU189B, LYS184A, LYS184B, LYS192A, LYS192B, LYS212A, LYS212B, PHE215A, PHE215B, PRO190A, PRO190B, PRO191A, PRO191B, THR177A, THR177B, TRP113A, TRP113B, TYR197A, TYR197B, VAL176A, VAL182A, VAL194A, VAL194B, VAL216A, VAL216B, VAL217A, VAL217B
• A-C: ALA74C, ARG173A, ARG181A, GLU174A, HIS33C, LYS36C, TYR145A
• A-D: ALA74A, ALA74D, ARG123A, ARG128A, ARG128D, ARG181D, ARG186A, ARG186D, ASN77A, ASN77D, ASN84D, ASP125A, ASP125D, ASP127A, ASP127D, ASP143A, ASP143D, ASP144A, ASP144D, ASP71A, ASP71D, CYS136A, CYS136D, GLN80D, GLU132A, GLU132D, GLU140A, GLU140D, GLU185A, GLU185D, GLU70A, GLU70D, GLY139A, GLY139D, GLY188A, GLY188D, HIS178A, HIS178D, HIS37A, HIS37D, HIS78A, HIS78D, ILE138A, ILE138D, ILE35A, ILE35D, ILE79A, ILE79D, LEU131A, LEU131D, LEU135A, LEU135D, LEU187A, LEU187D, LEU189A, LEU189D, LEU81A, LEU81D, LYS184A, LYS184D, LYS36A, LYS36D, PHE129A, PHE129D, PHE142A, PHE142D, PHE72A, PHE72D, PRO190A, PRO190D, PRO191D, SER124A, SER141A, SER141D, SER146D, THR68A, THR68D, TRP73A, TRP73D, TYR183A, TYR183D, TYR76A, TYR76D, VAL182A, VAL182D, VAL69A, VAL69D
• B-C: ALA74B, ALA74C, ARG123B, ARG123C, ARG128B, ARG128C, ARG181B, ARG181C, ARG186B, ARG186C, ASN77B, ASN77C, ASN84B, ASN84C, ASP125B, ASP125C, ASP127B, ASP127C, ASP143B, ASP143C, ASP144B, ASP144C, ASP71B, ASP71C, CYS136B, CYS136C, GLU132B, GLU132C, GLU140B, GLU140C, GLU185B, GLU185C, GLU70B, GLU70C, GLY139B, GLY139C, GLY188B, GLY188C, HIS178B, HIS178C, HIS37B, HIS37C, HIS78B, HIS78C, ILE138B, ILE138C, ILE35B, ILE35C, ILE79B, ILE79C, LEU131B, LEU131C, LEU135B, LEU135C, LEU187B, LEU187C, LEU189B, LEU189C, LEU81B, LEU81C, LYS184B, LYS184C, LYS36B, LYS36C, PHE129B, PHE129C, PHE142B, PHE142C, PHE72B, PHE72C, SER124B, SER124C, SER141B, SER141C, SER83B, SER83C, THR68B, TRP73B, TRP73C, TYR183B, TYR183C, TYR34C, TYR76B, TYR76C, VAL182B, VAL182C, VAL69B, VAL69C
• B-D: ARG173B, GLU174B, LYS36D
• C-D: HIS33C, ILE35D