3TEN

holo form of carbon disulfide hydrolase

• Total interactions analyzed: 28
• Total true interactions: 16
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 265
  • Norm. En. per Res.: -5.3734
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-204.7543	-41.0177	-1103.22	-1348.992	266	54	20	42741	14	128	117
A-D	-18.895	14.1285	-158.506	-163.2725	78	5	7	7118	0	26	24
A-E	-22.533	3.6267	-176.166	-195.0723	79	7	8	7557	0	26	25
A-F	-94.4053	-33.4066	-350.528	-478.3399	100	18	6	12435	4	50	36
B-C	-22.6284	-18.5326	-168.962	-210.123	78	5	7	7314	0	26	23
B-D	-95.2486	-54.0534	-383.682	-532.9841	102	20	7	13080	5	50	38
B-F	-39.7775	-12.5339	-177.188	-229.4995	75	11	9	7361	2	28	25
C-D	-234.7949	-50.4021	-1138.76	-1423.9569	265	48	21	43090	17	130	119
C-G	-102.5582	-31.0923	-341.31	-474.9605	102	14	5	12208	3	49	35
C-H	-18.629	0.0275	-186.205	-204.8064	79	6	9	7779	1	28	25
D-G	-25.1601	-6.3166	-176.395	-207.8717	78	9	8	7398	1	28	25
E-F	-202.6766	-37.4854	-1129.18	-1369.342	265	52	21	42960	15	130	115
E-G	-7.9877	-7.7925	-156.559	-172.3392	76	8	8	7179	1	27	26
E-H	-83.52	-28.54	-341.263	-453.3231	101	13	5	11858	1	49	34
F-H	-17.8901	-3.1671	-165.665	-186.7223	76	4	6	7233	1	26	25
G-H	-209.6669	-34.0241	-1116.62	-1360.311	266	49	21	42999	16	127	116

Interface residues

• A-B: ALA102A, ALA102B, ALA123A, ALA123B, ALA17A, ALA17B, ALA53A, ALA53B, ALA59A, ALA59B, ALA67A, ALA67B, ALA71A, ALA71B, ARG125A, ARG125B, ARG19A, ARG19B, ARG20A, ARG20B, ARG28A, ARG28B, ARG29A, ARG29B, ARG39A, ARG39B, ARG57A, ARG57B, ARG69A, ARG69B, ARG95A, ARG95B, ASN160A, ASN160B, ASN26A, ASN26B, ASN27A, ASN27B, ASN58A, ASN58B, ASN76A, ASN76B, ASP118A, ASP118B, ASP131A, ASP131B, ASP15A, ASP15B, ASP37A, ASP37B, ASP51A, ASP51B, ASP52A, ASP52B, ASP65A, ASP65B, ASP66A, ASP66B, ASP90A, ASP90B, CYS35A, CYS35B, CYS91A, CYS91B, GLN116A, GLN116B, GLN44A, GLN44B, GLN49A, GLN49B, GLU100A, GLU100B, GLU114A, GLU114B, GLU130A, GLU130B, GLU14A, GLU14B, GLU156A, GLU156B, GLU176A, GLU176B, GLU178A, GLU178B, GLU38A, GLU38B, GLU43A, GLU43B, GLU99B, GLY109A, GLY109B, GLY154A, GLY154B, GLY23A, GLY23B, GLY60A, GLY60B, GLY61A, GLY61B, GLY79A, GLY92A, GLY92B, GLY98A, GLY98B, HIS161A, HIS161B, HIS180A, HIS180B, HIS41A, HIS41B, HIS54A, HIS54B, HIS88A, HIS88B, ILE110A, ILE110B, ILE126A, ILE126B, ILE133A, ILE133B, ILE157A, ILE157B, ILE164A, ILE164B, ILE24A, ILE24B, ILE42A, ILE42B, ILE48A, ILE48B, ILE55A, ILE55B, ILE62A, ILE62B, ILE68A, ILE68B, LEU117A, LEU117B, LEU120A, LEU120B, LEU121A, LEU121B, LEU13A, LEU13B, LEU142A, LEU142B, LEU158A, LEU158B, LEU163A, LEU163B, LEU18A, LEU18B, LEU30A, LEU30B, LEU33A, LEU33B, LEU73A, LEU73B, LEU94A, LEU94B, LYS103A, LYS103B, LYS108A, LYS108B, LYS111A, LYS111B, LYS134A, LYS134B, LYS137A, LYS137B, LYS153A, LYS153B, LYS166A, LYS166B, LYS22A, LYS22B, MET150A, MET150B, MET36A, MET36B, MET93A, MET93B, PHE105A, PHE105B, PHE124A, PHE124B, PHE132A, PHE132B, PHE136A, PHE136B, PHE138A, PHE138B, PHE77A, PHE77B, PHE78A, PHE78B, PHE96A, PHE96B, PRO112A, PRO112B, PRO119A, PRO119B, PRO122A, PRO122B, PRO162A, PRO162B, PRO165A, PRO165B, PRO25A, PRO25B, PRO50A, PRO50B, SER127A, SER127B, SER128A, SER128B, SER70A, SER70B, SER72A, SER72B, THR179A, THR179B, THR34A, THR34B, THR64A, THR64B, THR74A, THR74B, THR75A, THR75B, THR80A, THR80B, THR89A, THR89B, THR97A, THR97B, TRP135A, TRP135B, TRP31A, TRP31B, TYR104A, TYR104B, TYR139A, TYR139B, TYR16A, TYR16B, TYR175A, TYR175B, TYR56A, TYR56B, VAL101A, VAL101B, VAL115A, VAL115B, VAL144A, VAL144B, VAL177A, VAL177B, VAL21A, VAL21B, VAL32A, VAL32B, VAL40A, VAL40B, VAL63A, VAL63B
• A-D: ALA17A, ARG169D, ARG181D, ARG183D, ARG19A, ARG20A, ARG28D, ARG29A, ASN191D, ASN26A, ASN76A, ASP15A, ASP7A, GLN187D, GLN44D, GLU14A, GLU176D, GLU192D, GLU197D, GLU43D, GLU4A, GLU82D, GLU9A, GLY172D, GLY199D, GLY23A, GLY47D, GLY79A, HIS198D, HIS54A, ILE170D, ILE188D, ILE189D, ILE201D, ILE24A, ILE42D, ILE48D, ILE6A, ILE83D, ILE84D, LEU10A, LEU13A, LEU182D, LEU18A, LEU30D, LEU46D, LEU73A, LYS11A, LYS184D, LYS195D, LYS203D, LYS22A, LYS81A, PHE196D, PHE77A, PHE78A, PRO185D, PRO25A, SER194D, SER3A, SER45D, SER8A, THR171D, THR179D, THR193D, THR200D, THR74A, THR75A, THR80A, TYR16A, TYR173D, TYR190D, TYR5A, VAL174D, VAL202D, VAL21A, VAL32D, VAL86D
• A-E: ALA17E, ARG169A, ARG181A, ARG183A, ARG19E, ARG20E, ARG28A, ARG29E, ASN191A, ASN26E, ASN76E, ASP15E, ASP7E, GLN187A, GLN44A, GLU14E, GLU176A, GLU192A, GLU197A, GLU43A, GLU4E, GLU82A, GLU9E, GLY172A, GLY199A, GLY23E, GLY47A, GLY79E, HIS198A, HIS54E, ILE170A, ILE188A, ILE189A, ILE201A, ILE24E, ILE42A, ILE48A, ILE6E, ILE83A, ILE84A, LEU10E, LEU13E, LEU182A, LEU18E, LEU30A, LEU46A, LEU73E, LYS11E, LYS184A, LYS195A, LYS203A, LYS22E, LYS81E, PHE196A, PHE77E, PHE78E, PRO185A, PRO25E, SER194A, SER3E, SER45A, SER8E, THR171A, THR179A, THR193A, THR200A, THR74E, THR75E, THR80E, TYR16E, TYR173A, TYR175A, TYR190A, TYR5E, VAL174A, VAL202A, VAL21E, VAL32A, VAL86A
• A-F: ARG181A, ARG181F, ARG183A, ARG183F, ARG39A, ARG39F, ARG95A, ARG95F, ASN186A, ASN186F, ASN191A, ASN191F, ASP141A, ASP141F, ASP148A, ASP148F, ASP90A, ASP90F, CYS91A, CYS91F, GLU100A, GLU100F, GLU140A, GLU140F, GLU149A, GLU149F, GLU176A, GLU176F, GLU178A, GLU178F, GLU192A, GLU192F, GLU197A, GLU197F, GLY199A, GLY199F, GLY92A, GLY92F, GLY98A, GLY98F, HIS180A, HIS180F, HIS198A, HIS198F, HIS88A, HIS88F, ILE188A, ILE188F, ILE189A, ILE189F, ILE201A, ILE201F, LEU94A, LEU94F, LYS145A, LYS145F, LYS195A, LYS195F, MET93A, MET93F, PHE138A, PHE138F, PHE196A, PHE196F, PHE96A, PHE96F, PRO147A, PRO147F, SER146A, SER146F, SER194A, SER194F, THR179A, THR179F, THR193A, THR193F, THR200A, THR200F, THR89A, THR89F, THR97A, THR97F, TYR104A, TYR104F, TYR139A, TYR139F, TYR175A, TYR175F, TYR190A, TYR190F, VAL101A, VAL101F, VAL144A, VAL144F, VAL174A, VAL174F, VAL177A, VAL177F, VAL202A, VAL202F
• B-C: ALA17C, ARG169B, ARG181B, ARG183B, ARG19C, ARG20C, ARG28B, ARG29C, ASN191B, ASN26C, ASN76C, ASP15C, ASP7C, GLN187B, GLN44B, GLU14C, GLU176B, GLU192B, GLU197B, GLU43B, GLU4C, GLU82B, GLU9C, GLY172B, GLY199B, GLY23C, GLY47B, GLY79C, HIS198B, HIS54C, ILE170B, ILE188B, ILE189B, ILE201B, ILE24C, ILE42B, ILE48B, ILE6C, ILE83B, ILE84B, LEU10C, LEU13C, LEU182B, LEU18C, LEU30B, LEU46B, LEU73C, LYS11C, LYS184B, LYS195B, LYS203B, LYS22C, LYS81C, PHE196B, PHE77C, PHE78C, PRO185B, PRO25C, SER194B, SER3C, SER45B, SER8C, THR171B, THR179B, THR193B, THR200B, THR74C, THR75C, THR80C, TYR16C, TYR173B, TYR190B, TYR5C, VAL174B, VAL202B, VAL21C, VAL32B, VAL86B
• B-D: ARG181B, ARG181D, ARG183B, ARG183D, ARG39B, ARG39D, ARG95B, ARG95D, ASN186B, ASN186D, ASN191B, ASN191D, ASP141B, ASP141D, ASP148B, ASP148D, ASP90B, ASP90D, CYS91B, CYS91D, GLU100B, GLU100D, GLU140B, GLU140D, GLU149B, GLU149D, GLU176B, GLU176D, GLU178B, GLU178D, GLU192B, GLU192D, GLU197B, GLU197D, GLY199B, GLY199D, GLY92B, GLY92D, GLY98B, GLY98D, HIS180B, HIS180D, HIS198B, HIS198D, HIS88B, HIS88D, ILE188B, ILE188D, ILE189B, ILE189D, ILE201B, ILE201D, LEU94B, LEU94D, LYS108B, LYS145B, LYS145D, LYS195B, LYS195D, LYS203D, MET93B, MET93D, PHE138B, PHE138D, PHE196B, PHE196D, PHE96B, PHE96D, PRO147B, PRO147D, SER146B, SER146D, SER194B, SER194D, THR179B, THR179D, THR193B, THR193D, THR200B, THR200D, THR89B, THR89D, THR97B, THR97D, TYR104B, TYR104D, TYR139B, TYR139D, TYR175B, TYR175D, TYR190B, TYR190D, VAL101B, VAL101D, VAL144B, VAL144D, VAL174B, VAL174D, VAL177B, VAL177D, VAL202B, VAL202D
• B-F: ALA17B, ARG169F, ARG181F, ARG183F, ARG19B, ARG20B, ARG28F, ARG29B, ASN191F, ASN26B, ASN76B, ASP15B, ASP7B, GLN187F, GLU14B, GLU192F, GLU197F, GLU4B, GLU82F, GLU9B, GLY172F, GLY199F, GLY23B, GLY47F, GLY79B, HIS198F, HIS54B, ILE170F, ILE188F, ILE189F, ILE201F, ILE24B, ILE42F, ILE48F, ILE6B, ILE83F, ILE84F, LEU10B, LEU13B, LEU182F, LEU18B, LEU30F, LEU46F, LEU73B, LYS11B, LYS184F, LYS195F, LYS203F, LYS22B, LYS81B, PHE196F, PHE77B, PHE78B, PRO185F, PRO25B, SER194F, SER3B, SER45F, SER8B, THR171F, THR179F, THR193F, THR200F, THR74B, THR75B, THR80B, TYR16B, TYR173F, TYR190F, TYR5B, VAL174F, VAL202F, VAL21B, VAL32F, VAL86F
• C-D: ALA102C, ALA102D, ALA123C, ALA123D, ALA17C, ALA17D, ALA53C, ALA53D, ALA59C, ALA59D, ALA67C, ALA67D, ALA71C, ALA71D, ARG125C, ARG125D, ARG19C, ARG19D, ARG20C, ARG20D, ARG28C, ARG28D, ARG29C, ARG29D, ARG39C, ARG39D, ARG57C, ARG57D, ARG69C, ARG69D, ARG95C, ARG95D, ASN160C, ASN160D, ASN26C, ASN26D, ASN27C, ASN27D, ASN58C, ASN58D, ASN76C, ASN76D, ASP118C, ASP118D, ASP131C, ASP131D, ASP15C, ASP15D, ASP167C, ASP167D, ASP37C, ASP37D, ASP51C, ASP51D, ASP52C, ASP52D, ASP65C, ASP65D, ASP66C, ASP66D, ASP90C, ASP90D, CYS35C, CYS35D, CYS91C, CYS91D, GLN116C, GLN116D, GLN44C, GLN44D, GLN49C, GLN49D, GLU100C, GLU100D, GLU114C, GLU114D, GLU130C, GLU130D, GLU14C, GLU14D, GLU156D, GLU176C, GLU176D, GLU178C, GLU178D, GLU38C, GLU38D, GLU43C, GLU43D, GLY109C, GLY109D, GLY154C, GLY154D, GLY23C, GLY23D, GLY60C, GLY60D, GLY61C, GLY61D, GLY92C, GLY92D, GLY98C, GLY98D, HIS161C, HIS161D, HIS180C, HIS180D, HIS41C, HIS41D, HIS54C, HIS54D, HIS88C, HIS88D, ILE110C, ILE110D, ILE126C, ILE126D, ILE133C, ILE133D, ILE157C, ILE157D, ILE164C, ILE164D, ILE24C, ILE24D, ILE42C, ILE42D, ILE48C, ILE48D, ILE55C, ILE55D, ILE62C, ILE62D, ILE68C, ILE68D, LEU117C, LEU117D, LEU120C, LEU120D, LEU121C, LEU121D, LEU13C, LEU13D, LEU142C, LEU142D, LEU158C, LEU158D, LEU163C, LEU163D, LEU18C, LEU18D, LEU30C, LEU30D, LEU33C, LEU33D, LEU73C, LEU73D, LEU94C, LEU94D, LYS103C, LYS103D, LYS108C, LYS108D, LYS111C, LYS111D, LYS134C, LYS134D, LYS137C, LYS137D, LYS153C, LYS153D, LYS166C, LYS166D, LYS22C, LYS22D, MET150C, MET150D, MET36C, MET36D, MET93C, MET93D, PHE105C, PHE105D, PHE124C, PHE124D, PHE132C, PHE132D, PHE136C, PHE136D, PHE138C, PHE138D, PHE77C, PHE77D, PHE78C, PHE78D, PHE96C, PHE96D, PRO112C, PRO112D, PRO119C, PRO119D, PRO122C, PRO122D, PRO162C, PRO162D, PRO165C, PRO165D, PRO25C, PRO25D, PRO50C, PRO50D, SER127C, SER127D, SER128C, SER128D, SER70C, SER70D, SER72C, SER72D, THR179C, THR179D, THR34C, THR34D, THR64C, THR64D, THR74C, THR74D, THR75C, THR75D, THR80C, THR80D, THR89C, THR89D, THR97C, THR97D, TRP135C, TRP135D, TRP31C, TRP31D, TYR104C, TYR104D, TYR139C, TYR139D, TYR16C, TYR16D, TYR175C, TYR175D, TYR56C, TYR56D, VAL101C, VAL101D, VAL115C, VAL115D, VAL144C, VAL144D, VAL177C, VAL177D, VAL21C, VAL21D, VAL32C, VAL32D, VAL40C, VAL40D, VAL63C, VAL63D
• C-G: ARG181C, ARG181G, ARG183C, ARG183G, ARG39C, ARG39G, ARG95C, ARG95G, ASN186C, ASN186G, ASN191C, ASN191G, ASP141C, ASP141G, ASP148C, ASP148G, ASP90C, ASP90G, CYS91C, CYS91G, GLU100C, GLU100G, GLU140C, GLU140G, GLU149C, GLU149G, GLU176C, GLU176G, GLU178C, GLU178G, GLU192C, GLU192G, GLU197C, GLU197G, GLY199C, GLY199G, GLY92C, GLY92G, GLY98C, GLY98G, HIS180C, HIS180G, HIS198C, HIS198G, HIS88C, HIS88G, ILE188C, ILE188G, ILE189C, ILE189G, ILE201C, ILE201G, LEU94C, LEU94G, LYS108G, LYS145C, LYS145G, LYS195C, LYS195G, LYS203C, LYS203G, MET93C, MET93G, PHE138C, PHE138G, PHE196C, PHE196G, PHE96C, PHE96G, PRO147C, PRO147G, SER146C, SER146G, SER194C, SER194G, THR179C, THR179G, THR193C, THR193G, THR200C, THR200G, THR89C, THR89G, THR97C, THR97G, TYR104C, TYR104G, TYR139C, TYR139G, TYR175G, TYR190C, TYR190G, VAL101C, VAL101G, VAL144C, VAL144G, VAL174C, VAL174G, VAL177C, VAL177G, VAL202C, VAL202G
• C-H: ALA17H, ARG12H, ARG169C, ARG181C, ARG183C, ARG19H, ARG20H, ARG28C, ARG29H, ASN191C, ASN26H, ASN76H, ASP15H, ASP7H, GLN187C, GLN44C, GLU14H, GLU176C, GLU192C, GLU197C, GLU4H, GLU82C, GLU9H, GLY172C, GLY199C, GLY23H, GLY47C, GLY79H, HIS198C, HIS54H, ILE170C, ILE188C, ILE189C, ILE201C, ILE24H, ILE42C, ILE48C, ILE6H, ILE83C, ILE84C, LEU10H, LEU13H, LEU182C, LEU18H, LEU30C, LEU46C, LEU73H, LYS11H, LYS184C, LYS195C, LYS203C, LYS22H, LYS81H, PHE196C, PHE77H, PHE78H, PRO185C, PRO25H, SER194C, SER3H, SER45C, SER8H, THR171C, THR179C, THR193C, THR200C, THR74H, THR75H, THR80H, TYR16H, TYR173C, TYR175C, TYR190C, TYR5H, VAL174C, VAL202C, VAL21H, VAL32C, VAL86C
• D-G: ALA17D, ARG12D, ARG169G, ARG181G, ARG183G, ARG19D, ARG20D, ARG28G, ARG29D, ASN191G, ASN26D, ASN76D, ASP15D, ASP7D, GLN187G, GLN44G, GLU14D, GLU176G, GLU192G, GLU197G, GLU4D, GLU82G, GLU9D, GLY172G, GLY199G, GLY23D, GLY47G, GLY79D, HIS198G, HIS54D, ILE170G, ILE188G, ILE189G, ILE201G, ILE24D, ILE42G, ILE48G, ILE6D, ILE83G, ILE84G, LEU10D, LEU13D, LEU182G, LEU18D, LEU30G, LEU46G, LEU73D, LYS11D, LYS184G, LYS195G, LYS203G, LYS22D, LYS81D, PHE196G, PHE77D, PHE78D, PRO185G, PRO25D, SER194G, SER3D, SER45G, SER8D, THR171G, THR179G, THR193G, THR200G, THR74D, THR75D, THR80D, TYR16D, TYR173G, TYR190G, TYR5D, VAL174G, VAL202G, VAL21D, VAL32G, VAL86G
• E-F: ALA102E, ALA102F, ALA123E, ALA123F, ALA17E, ALA17F, ALA53E, ALA53F, ALA59E, ALA59F, ALA67E, ALA67F, ALA71E, ALA71F, ARG125E, ARG125F, ARG19E, ARG19F, ARG20E, ARG20F, ARG28E, ARG28F, ARG29E, ARG29F, ARG39E, ARG39F, ARG57E, ARG57F, ARG69E, ARG69F, ARG95E, ARG95F, ASN160E, ASN160F, ASN26E, ASN26F, ASN27E, ASN27F, ASN58E, ASN58F, ASN76E, ASN76F, ASP118E, ASP118F, ASP131E, ASP131F, ASP15E, ASP15F, ASP167E, ASP37E, ASP37F, ASP51E, ASP51F, ASP52E, ASP52F, ASP65E, ASP65F, ASP66E, ASP66F, ASP90E, ASP90F, CYS35E, CYS35F, CYS91E, CYS91F, GLN116E, GLN116F, GLN44E, GLN44F, GLN49E, GLN49F, GLU100E, GLU100F, GLU114E, GLU114F, GLU130E, GLU130F, GLU14E, GLU14F, GLU156F, GLU176E, GLU176F, GLU178E, GLU178F, GLU38E, GLU38F, GLU43E, GLU43F, GLU99F, GLY109E, GLY109F, GLY154E, GLY154F, GLY23E, GLY23F, GLY60E, GLY60F, GLY61E, GLY61F, GLY92E, GLY92F, GLY98E, GLY98F, HIS161E, HIS161F, HIS180E, HIS180F, HIS41E, HIS41F, HIS54E, HIS54F, HIS88E, HIS88F, ILE110E, ILE110F, ILE126E, ILE126F, ILE133E, ILE133F, ILE157E, ILE157F, ILE164E, ILE164F, ILE24E, ILE24F, ILE42E, ILE42F, ILE48E, ILE48F, ILE55E, ILE55F, ILE62E, ILE62F, ILE68E, ILE68F, LEU117E, LEU117F, LEU120E, LEU120F, LEU121E, LEU121F, LEU13E, LEU13F, LEU142E, LEU142F, LEU158E, LEU158F, LEU163E, LEU163F, LEU18E, LEU18F, LEU30E, LEU30F, LEU33E, LEU33F, LEU73E, LEU73F, LEU94E, LEU94F, LYS103E, LYS103F, LYS108E, LYS108F, LYS111E, LYS111F, LYS134E, LYS134F, LYS137E, LYS137F, LYS153E, LYS153F, LYS166E, LYS166F, LYS22E, LYS22F, MET150E, MET150F, MET36E, MET36F, MET93E, MET93F, PHE105E, PHE105F, PHE124E, PHE124F, PHE132E, PHE132F, PHE136E, PHE136F, PHE138E, PHE138F, PHE77E, PHE77F, PHE78E, PHE78F, PHE96E, PHE96F, PRO112E, PRO112F, PRO119E, PRO119F, PRO122E, PRO122F, PRO162E, PRO162F, PRO165E, PRO165F, PRO25E, PRO25F, PRO50E, PRO50F, SER127E, SER127F, SER128E, SER128F, SER70E, SER70F, SER72E, SER72F, THR179E, THR179F, THR34E, THR34F, THR64E, THR64F, THR74E, THR74F, THR75E, THR75F, THR80E, THR80F, THR89E, THR89F, THR97E, THR97F, TRP135E, TRP135F, TRP31E, TRP31F, TYR104E, TYR104F, TYR139E, TYR139F, TYR16E, TYR16F, TYR175E, TYR175F, TYR56E, TYR56F, VAL101E, VAL101F, VAL115E, VAL115F, VAL144E, VAL144F, VAL177E, VAL177F, VAL21E, VAL21F, VAL32E, VAL32F, VAL40E, VAL40F, VAL63E, VAL63F
• E-G: ALA17G, ARG169E, ARG181E, ARG183E, ARG19G, ARG20G, ARG28E, ARG29G, ASN191E, ASN26G, ASN76G, ASP15G, ASP7G, GLN187E, GLN44E, GLU14G, GLU176E, GLU192E, GLU197E, GLU43E, GLU4G, GLU82E, GLU9G, GLY172E, GLY199E, GLY23G, GLY47E, GLY79G, HIS198E, HIS54G, ILE188E, ILE189E, ILE201E, ILE24G, ILE42E, ILE48E, ILE6G, ILE83E, ILE84E, LEU10G, LEU13G, LEU182E, LEU18G, LEU30E, LEU46E, LEU73G, LYS11G, LYS184E, LYS195E, LYS203E, LYS22G, LYS81G, PHE196E, PHE77G, PHE78G, PRO185E, PRO25G, SER194E, SER3G, SER45E, SER8G, THR171E, THR179E, THR193E, THR200E, THR74G, THR75G, THR80G, TYR16G, TYR173E, TYR190E, TYR5G, VAL174E, VAL202E, VAL21G, VAL86E
• E-H: ARG181E, ARG181H, ARG183E, ARG183H, ARG39E, ARG39H, ARG95E, ARG95H, ASN191E, ASN191H, ASP141E, ASP141H, ASP148E, ASP148H, ASP90E, ASP90H, CYS91E, CYS91H, GLU100E, GLU100H, GLU140E, GLU140H, GLU149E, GLU149H, GLU176E, GLU176H, GLU178E, GLU178H, GLU192E, GLU192H, GLU197E, GLU197H, GLY199E, GLY199H, GLY92E, GLY92H, GLY98E, GLY98H, HIS180E, HIS180H, HIS198E, HIS198H, HIS88E, HIS88H, ILE188E, ILE188H, ILE189E, ILE189H, ILE201E, ILE201H, LEU94E, LEU94H, LYS108H, LYS145E, LYS145H, LYS195E, LYS195H, LYS203E, LYS203H, MET93E, MET93H, PHE138E, PHE138H, PHE196E, PHE196H, PHE96E, PHE96H, PRO147E, PRO147H, SER146E, SER146H, SER194E, SER194H, THR179E, THR179H, THR193E, THR193H, THR200E, THR200H, THR89E, THR89H, THR97E, THR97H, TYR104E, TYR104H, TYR139E, TYR139H, TYR175E, TYR175H, TYR190E, TYR190H, VAL101E, VAL101H, VAL144E, VAL144H, VAL174E, VAL174H, VAL177E, VAL177H, VAL202E, VAL202H
• F-H: ALA17F, ARG169H, ARG181H, ARG183H, ARG19F, ARG20F, ARG28H, ARG29F, ASN191H, ASN26F, ASN76F, ASP15F, ASP7F, GLN187H, GLN44H, GLU14F, GLU176H, GLU192H, GLU197H, GLU43H, GLU4F, GLU82H, GLU9F, GLY172H, GLY199H, GLY23F, GLY47H, GLY79F, HIS198H, HIS54F, ILE188H, ILE189H, ILE201H, ILE24F, ILE42H, ILE48H, ILE6F, ILE83H, ILE84H, LEU10F, LEU13F, LEU182H, LEU18F, LEU30H, LEU46H, LEU73F, LYS11F, LYS184H, LYS195H, LYS203H, LYS22F, LYS81F, PHE196H, PHE77F, PHE78F, PRO185H, PRO25F, SER194H, SER3F, SER45H, SER8F, THR171H, THR179H, THR193H, THR200H, THR74F, THR75F, THR80F, TYR16F, TYR173H, TYR190H, TYR5F, VAL174H, VAL202H, VAL21F, VAL86H
• G-H: ALA102G, ALA102H, ALA123G, ALA123H, ALA17G, ALA17H, ALA53G, ALA53H, ALA59G, ALA59H, ALA67G, ALA67H, ALA71G, ALA71H, ARG125G, ARG125H, ARG19G, ARG19H, ARG20G, ARG20H, ARG28G, ARG28H, ARG29G, ARG29H, ARG39G, ARG39H, ARG57G, ARG57H, ARG69G, ARG69H, ARG95G, ARG95H, ASN160G, ASN160H, ASN26G, ASN26H, ASN27G, ASN27H, ASN58G, ASN58H, ASN76G, ASN76H, ASP118G, ASP118H, ASP131G, ASP131H, ASP15G, ASP15H, ASP37G, ASP37H, ASP51G, ASP51H, ASP52G, ASP52H, ASP65G, ASP65H, ASP66G, ASP66H, ASP90G, ASP90H, CYS35G, CYS35H, CYS91G, CYS91H, GLN116G, GLN116H, GLN44G, GLN44H, GLN49G, GLN49H, GLU100G, GLU100H, GLU114G, GLU114H, GLU130G, GLU130H, GLU14G, GLU14H, GLU156G, GLU156H, GLU176G, GLU176H, GLU178G, GLU178H, GLU38G, GLU38H, GLU43G, GLU43H, GLU99G, GLU99H, GLY109G, GLY109H, GLY154G, GLY154H, GLY23G, GLY23H, GLY60G, GLY60H, GLY61G, GLY61H, GLY92G, GLY92H, GLY98G, GLY98H, HIS161G, HIS161H, HIS180G, HIS180H, HIS41G, HIS41H, HIS54G, HIS54H, HIS88G, HIS88H, ILE110G, ILE110H, ILE126G, ILE126H, ILE133G, ILE133H, ILE157G, ILE157H, ILE164G, ILE164H, ILE24G, ILE24H, ILE42G, ILE42H, ILE48G, ILE48H, ILE55G, ILE55H, ILE62G, ILE62H, ILE68G, ILE68H, LEU117G, LEU117H, LEU120G, LEU120H, LEU121G, LEU121H, LEU13G, LEU13H, LEU142G, LEU142H, LEU158G, LEU158H, LEU163G, LEU163H, LEU18G, LEU18H, LEU30G, LEU30H, LEU33G, LEU33H, LEU73G, LEU73H, LEU94G, LEU94H, LYS103G, LYS103H, LYS108G, LYS108H, LYS111G, LYS111H, LYS134G, LYS134H, LYS137G, LYS137H, LYS153G, LYS153H, LYS166G, LYS166H, LYS22G, LYS22H, MET150G, MET150H, MET36G, MET36H, MET93G, MET93H, PHE105G, PHE105H, PHE124G, PHE124H, PHE132G, PHE132H, PHE136G, PHE136H, PHE138G, PHE138H, PHE77G, PHE77H, PHE78G, PHE78H, PHE96G, PHE96H, PRO112G, PRO112H, PRO119G, PRO119H, PRO122G, PRO122H, PRO162G, PRO162H, PRO165G, PRO165H, PRO25G, PRO25H, PRO50G, PRO50H, SER127G, SER127H, SER128G, SER128H, SER70G, SER70H, SER72G, SER72H, THR179G, THR179H, THR34G, THR34H, THR64G, THR64H, THR74G, THR74H, THR75G, THR75H, THR80G, THR80H, THR89G, THR89H, THR97G, THR97H, TRP135G, TRP135H, TRP31G, TRP31H, TYR104G, TYR104H, TYR139G, TYR139H, TYR16G, TYR16H, TYR175G, TYR175H, TYR56G, TYR56H, VAL101G, VAL101H, VAL115G, VAL115H, VAL144G, VAL144H, VAL177G, VAL177H, VAL21G, VAL21H, VAL32G, VAL32H, VAL40G, VAL40H, VAL63G, VAL63H