3T1N

structure of human microcephalin (mcph1) tandem brct domains in complex with a cdc27 phosphopeptide

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 27
  • Norm. En. per Res.: -3.4395
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-10.9453	1.1011	-92.2453	-102.0896	73	5	2	4399	2	14	23
A-C	-20.6912	-8.6262	-63.548	-92.8655	27	3	2	2264	0	9	4
B-D	-17.5695	-9.5061	-55.3403	-82.4158	26	2	1	2072	0	9	4

Interface residues

• A-B: ALA748A, ALA748B, ALA757B, ALA773B, ARG648A, ARG703A, ARG703B, ARG741A, ARG752A, ARG752B, ARG785B, ARG791B, ASP758B, CYS680A, CYS744A, CYS776B, GLN759B, GLN788B, GLN792B, GLU681A, GLU681B, GLU725A, GLU726A, GLU777A, GLU777B, GLY672A, GLY720A, GLY749A, GLY749B, GLY753A, GLY783B, GLY784B, HIS685A, HIS721A, HIS745A, HIS780A, HIS780B, ILE723A, LEU719A, LEU746A, LEU781A, LEU781B, LYS644A, LYS645A, LYS774B, MET762B, PHE673A, PHE756B, PHE763B, PRO646A, PRO727A, PRO750A, PRO750B, PRO760B, PRO766B, SER674A, SER724A, SER747A, SER747B, SER787B, THR647A, THR682A, THR684A, THR754B, TRP706A, TRP712A, TRP722A, TYR751A, VAL761B, VAL764B, VAL772B, VAL786B, VAL789B
• A-C: ARG693A, ASN696A, ASP818A, ASP822C, GLU813A, GLU823C, LEU692A, LEU695A, LEU698A, LEU775A, LEU778A, LEU817A, LYS690A, LYS774A, LYS814A, PHE734A, PHE824C, PRO691A, PRO770A, PRO771A, SER654A, SER768A, SER769A, THR653A, THR694A, THR821A, VAL697A
• B-D: ARG693B, ASN696B, ASP818B, ASP822D, GLU813B, GLU823D, LEU692B, LEU695B, LEU698B, LEU775B, LEU778B, LEU817B, LYS690B, LYS814B, PHE734B, PHE824D, PRO691B, PRO770B, PRO771B, SER654B, SER768B, SER769B, THR653B, THR694B, THR821B, VAL697B