3SY2

crystal structure of the salmonella e3 ubiquitin ligase sopa in complex with the human e2 ubch7

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 67
  • Norm. En. per Res.: -2.8442
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	0.0	-0.7979	-0.7979	10	0	0	150	0	0	2
A-C	0.0	-11.7871	-78.7359	-90.523	39	2	4	3052	0	21	23
A-D	-9.3015	-32.3463	-148.912	-190.5598	67	15	4	6216	0	18	15
B-C	-5.0109	-31.8711	-146.881	-183.7629	69	6	4	5857	1	16	14
B-D	-8.0512	0.0	-50.9698	-59.021	41	0	4	2437	0	19	21

Interface residues

• A-B: ARG586B, GLN578A, GLN578B, GLU583A, GLU583B, HIS587A, HIS587B, SER580A, SER580B, VAL582B
• A-C: ALA123C, ALA126C, ALA729A, ARG122C, ARG586A, ARG763A, ASP124C, ASP80C, GLN680A, GLN736A, GLU118C, GLU127C, GLU128C, GLU684A, GLU81C, GLU93C, HIS119C, HIS764A, ILE730A, LEU121C, LEU125C, LYS131C, LYS767A, PHE731A, PHE769A, PRO117C, PRO120C, PRO728A, PRO732A, PRO770A, PRO77C, SER130C, SER727A, SER733A, SER734A, THR678A, TRP724A, TYR129C, TYR768A
• A-D: ALA2D, ALA3D, ALA527A, ALA528A, ALA561A, ALA577A, ALA59D, ALA92D, ALA98D, ARG526A, ARG5D, ARG6D, ASN511A, ASN516A, ASN530A, ASN564A, ASN573A, ASN94D, ASP518A, ASP522A, ASP529A, ASP548A, ASP563A, GLN578A, GLU10D, GLU12D, GLU13D, GLU572A, GLU60D, GLU93D, GLY512A, GLY515A, HIS510A, ILE579A, LEU513A, LEU545A, LEU567A, LEU568A, LYS100D, LYS64D, LYS96D, LYS9D, MET1D, MET544A, MET8D, PHE514A, PHE565A, PHE63D, PRO521A, PRO62D, PRO65D, PRO97D, SER4D, SER520A, SER546A, SER575A, SER91D, THR524A, THR525A, THR549A, THR576A, THR99D, TRP95D, TYR517A, TYR566A, TYR61D, VAL574A
• B-C: ALA2C, ALA3C, ALA527B, ALA528B, ALA561B, ALA577B, ALA59C, ALA92C, ALA98C, ARG526B, ARG5C, ARG6C, ASN511B, ASN516B, ASN530B, ASN564B, ASN573B, ASN94C, ASP518B, ASP522B, ASP529B, ASP548B, ASP563B, GLN578B, GLU10C, GLU12C, GLU13C, GLU572B, GLU60C, GLU93C, GLY512B, GLY515B, HIS510B, ILE579B, LEU513B, LEU545B, LEU567B, LEU568B, LYS100C, LYS64C, LYS96C, LYS9C, MET1C, MET544B, MET8C, PHE514B, PHE565B, PHE63C, PRO521B, PRO62C, PRO65C, PRO97C, SER4C, SER520B, SER546B, SER575B, SER91C, THR524B, THR525B, THR547B, THR549B, THR576B, THR99C, TRP523B, TRP95C, TYR517B, TYR566B, TYR61C, VAL574B
• B-D: ALA123D, ALA126D, ALA390B, ALA729B, ALA765B, ARG122D, ARG393B, ARG586B, ARG763B, ASP124D, ASP80D, GLN680B, GLU118D, GLU127D, GLU128D, GLU684B, GLU81D, GLU93D, HIS119D, HIS764B, ILE730B, LEU121D, LEU125D, LYS131D, LYS767B, PHE731B, PHE769B, PRO117D, PRO120D, PRO728B, PRO732B, PRO770B, PRO77D, SER130D, SER727B, SER733B, SER734B, THR678B, TRP724B, TYR129D, TYR768B