3SW2

x-ray crystal structure of human fxa in complex with 6-chloro-n-((3s)- 2-oxo-1-(2-oxo-2-((5s)-8-oxo-5,6-dihydro-1h-1,5-methanopyrido[1,2- a][1,5]diazocin-3(2h,4h,8h)-yl)ethyl)piperidin-3-yl)naphthalene-2- sulfonamide

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 78
  • Norm. En. per Res.: 4.1067
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-46.7216	-22.2832	389.326	320.3211	78	16	3	9020	1	14	17

Interface residues

• A-B: ALA119B, ALA121B, ALA128B, ALA152A, ALA163A, ARG115B, ARG125B, ARG153A, ARG202B, ASN117B, ASN133A, ASP126B, ASP132A, ASP135A, ASP137A, ASP205B, ASP239B, ASP24B, CYS122B, CYS129A, CYS136A, CYS140A, CYS149A, CYS151A, CYS164A, CYS172A, CYS22B, CYS27B, GLN133B, GLN138A, GLN175A, GLU124B, GLU26B, GLY134A, GLY154A, GLY173A, GLY25B, HIS141A, ILE137B, ILE46B, LEU123B, LEU131A, LEU131B, LEU177A, LEU235B, LEU47B, LYS162A, LYS174A, LYS204B, LYS23B, MET116B, MET157B, MET242B, PHE114B, PHE139A, PHE203B, PHE208B, PRO120B, PRO124B, PRO169A, PRO171A, PRO28B, SER130A, SER130B, SER150A, SER48B, THR113B, THR131B, THR176A, THR206B, TRP127B, TRP29B, TYR155A, TYR170A, TYR207B, VAL118B, VAL200B, VAL209B