3SOM

crystal structure of human mmachc

• Total interactions analyzed: 120
• Total true interactions: 32
• Strongest Interaction:
  • Chains: D-F
  • Int. Res.: 83
  • Norm. En. per Res.: -3.1327
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-11.5542	-17.9185	-134.182	-163.6547	93	1	3	7076	0	30	28
A-C	-17.8102	3.0628	-162.785	-177.5324	68	7	0	5279	0	5	12
A-D	-3.3948	13.7467	-112.683	-102.3311	53	3	0	4139	0	7	6
B-C	0.0	11.9009	-116.765	-104.8641	53	3	0	4149	0	6	5
B-D	-14.7255	3.5231	-150.916	-162.1184	66	6	0	5172	0	5	12
C-D	-5.4143	-6.102	-129.627	-141.1432	83	3	3	6650	2	33	26
C-E	0.0	2.1418	-13.1329	-10.9911	18	0	0	700	0	16	10
D-F	-50.0715	38.7483	-248.689	-260.0122	83	14	0	9472	0	46	39
E-F	-13.7536	-12.524	-150.685	-176.9626	90	4	3	7368	4	33	28
E-G	-19.8412	3.5785	-148.59	-164.8527	68	5	0	5062	0	4	12
E-H	-7.3183	14.2811	-115.006	-108.0432	54	2	0	4087	0	6	6
F-G	-3.6597	13.1786	-122.015	-112.4961	52	3	0	4206	0	6	8
F-H	-12.9007	3.4794	-151.719	-161.1403	67	5	0	5098	0	4	12
G-H	0.0	-6.2906	-117.019	-123.3096	88	3	3	6529	0	30	28
G-I	-8.8644	5.2565	-160.357	-163.965	72	4	0	6950	0	42	31
G-J	0.0	0.0	-1.2649	-1.2649	2	0	0	36	0	0	1
H-I	0.0	0.0	-0.4133	-0.4133	2	0	0	36	0	0	1
H-J	-10.9813	35.19	-162.44	-138.2313	74	2	0	6915	0	42	31
I-J	-2.5182	-19.1031	-138.122	-159.7433	91	1	2	7089	0	30	28
I-K	-13.076	3.3745	-146.208	-155.9095	67	4	0	4962	0	4	12
I-L	-8.593	15.7199	-125.45	-118.3231	54	2	0	4288	0	6	7
J-K	-4.5105	18.2764	-117.8	-104.0341	51	4	0	4182	0	6	7
J-L	-17.6691	3.8268	-147.855	-161.6973	67	5	0	4991	0	4	12
K-L	-8.0752	-0.8055	-131.061	-139.9417	85	3	3	6588	1	33	28
K-N	0.0	0.0	-10.7439	-10.7439	18	0	0	611	0	16	10
L-M	-38.8784	43.5914	-234.23	-229.517	85	11	0	9328	0	45	37
M-N	-13.5056	-10.6434	-138.279	-162.428	89	1	3	6890	2	33	28
M-O	-20.8737	3.0037	-159.848	-177.7181	68	9	0	5305	0	4	12
M-P	-3.5031	13.97	-110.028	-99.5612	54	2	0	4062	0	6	6
N-O	-7.5627	13.4302	-109.609	-103.7415	53	2	0	4054	0	6	5
N-P	-19.782	3.134	-159.265	-175.9131	68	6	0	5297	0	4	12
O-P	-8.007	-1.0948	-122.37	-131.4718	88	0	3	6341	0	31	28

Interface residues

• A-B: ALA103A, ALA103B, ALA228A, ALA228B, ALA38A, ALA38B, ALA84A, ALA84B, ARG111A, ARG111B, ARG112A, ARG112B, ARG230A, ARG230B, ARG73A, ARG73B, ARG91A, ARG91B, ASN110A, ASN110B, ASP104A, ASP104B, ASP77A, ASP77B, ASP80A, ASP80B, CYS70A, CYS70B, GLN229B, GLN81A, GLN81B, GLN98A, GLN98B, GLU100A, GLU100B, GLU106A, GLU106B, GLY88B, HIS108A, HIS108B, HIS40A, HIS40B, HIS71A, HIS71B, ILE101A, ILE101B, ILE102A, ILE102B, ILE115A, ILE115B, ILE99A, ILE99B, LEU116B, LEU165A, LEU165B, LEU41A, LEU41B, LEU43A, LEU43B, LEU72A, LEU72B, LEU75A, LEU75B, LEU87A, LEU87B, LYS114A, LYS114B, PHE39A, PHE39B, PRO109A, PRO109B, PRO113A, PRO113B, PRO226A, PRO226B, PRO227A, PRO227B, PRO42A, PRO42B, PRO78A, PRO78B, THR76A, THR76B, TYR105A, TYR105B, TYR31A, TYR31B, VAL107A, VAL107B, VAL163A, VAL163B, VAL79A, VAL79B
• A-C: ALA137A, ALA137C, ALA38A, ALA38C, ARG111A, ARG111C, ARG112A, ARG112C, ARG132A, ARG132C, ARG144A, ARG144C, ASN110A, ASN110C, ASN142A, ASN142C, ASP138A, ASP138C, GLN133A, GLN133C, GLN143A, GLN143C, GLU106A, GLU106C, GLU136A, GLU136C, GLY141A, GLY141C, HIS108A, HIS108C, HIS40A, HIS40C, ILE115A, ILE115C, ILE145A, ILE145C, LEU116A, LEU116C, LEU35A, LEU35C, LEU41A, LEU41C, LYS114A, LYS114C, PHE39A, PHE39C, PRO109A, PRO109C, PRO113A, PRO113C, PRO139A, PRO139C, PRO36A, PRO36C, PRO37A, PRO37C, PRO42A, PRO42C, SER146A, SER146C, TRP140A, TRP140C, TYR31A, TYR31C, VAL107A, VAL107C, VAL135A, VAL135C
• A-D: ALA228A, ALA228D, ARG132A, ARG132D, ARG144A, ARG144D, ARG186A, ARG201A, ARG201D, ARG230A, ARG230D, ASN142A, ASN142D, ASN197A, ASN197D, ASP138A, ASP138D, ASP202A, ASP202D, GLN143A, GLN143D, GLN229A, GLN229D, GLU194A, GLU194D, GLY141A, GLY141D, HIS199A, HIS199D, ILE145A, ILE145D, ILE190A, ILE190D, LEU75A, LEU75D, PHE196A, PHE196D, PHE198A, PHE198D, PRO139A, PRO139D, PRO226A, PRO226D, PRO227A, PRO227D, SER224A, SER224D, THR225A, THR225D, TRP140A, TRP140D, TRP200A, TRP200D
• B-C: ALA228B, ALA228C, ARG132B, ARG132C, ARG144B, ARG144C, ARG186B, ARG201B, ARG201C, ARG230B, ARG230C, ASN142B, ASN142C, ASN197B, ASN197C, ASP138B, ASP138C, ASP202B, ASP202C, GLN143B, GLN143C, GLN229B, GLN229C, GLU194B, GLU194C, GLY141B, GLY141C, HIS199B, HIS199C, ILE145B, ILE145C, ILE190B, ILE190C, LEU231C, LEU75B, LEU75C, PHE196B, PHE198B, PHE198C, PRO139B, PRO139C, PRO226B, PRO226C, PRO227B, PRO227C, SER224B, SER224C, THR225B, THR225C, TRP140B, TRP140C, TRP200B, TRP200C
• B-D: ALA137B, ALA137D, ALA38B, ALA38D, ARG111B, ARG112B, ARG112D, ARG132B, ARG132D, ARG144B, ARG144D, ASN110B, ASN110D, ASN142B, ASN142D, ASP138B, ASP138D, GLN133B, GLN133D, GLN143B, GLN143D, GLU106B, GLU136B, GLU136D, GLY141B, GLY141D, HIS108B, HIS108D, HIS40B, HIS40D, ILE115B, ILE115D, ILE145B, ILE145D, LEU116B, LEU116D, LEU35B, LEU35D, LEU41B, LEU41D, LYS114B, LYS114D, PHE39B, PHE39D, PRO109B, PRO109D, PRO113B, PRO113D, PRO139B, PRO139D, PRO36B, PRO36D, PRO37B, PRO37D, PRO42B, PRO42D, SER146B, SER146D, TRP140B, TRP140D, TYR31B, TYR31D, VAL107B, VAL107D, VAL135B, VAL135D
• C-D: ALA228C, ALA228D, ALA38C, ALA38D, ARG111C, ARG111D, ARG112C, ARG112D, ARG230C, ARG230D, ARG73C, ARG73D, ARG91C, ARG91D, ASN110C, ASN110D, ASP104C, ASP104D, ASP77C, ASP77D, ASP80C, ASP80D, GLN81C, GLN81D, GLN98C, GLN98D, GLU100C, GLU100D, GLU106C, GLU106D, HIS108C, HIS108D, HIS40C, HIS40D, HIS71C, HIS71D, ILE101C, ILE101D, ILE102C, ILE102D, ILE115C, ILE115D, ILE99C, ILE99D, LEU165C, LEU165D, LEU41C, LEU41D, LEU43C, LEU43D, LEU72C, LEU72D, LEU75C, LEU75D, LYS114C, LYS114D, PHE39C, PHE39D, PRO109C, PRO109D, PRO113C, PRO113D, PRO167C, PRO167D, PRO226C, PRO226D, PRO227C, PRO227D, PRO42C, PRO42D, PRO78C, PRO78D, THR76C, THR76D, TYR105C, TYR105D, TYR31C, TYR31D, VAL107C, VAL107D, VAL163C, VAL163D, VAL79D
• C-E: ARG89C, ARG89E, ARG91C, ARG91E, GLU92C, GLU92E, GLU96C, GLU96E, LEU94C, LEU94E, LYS11E, PRO95C, PRO95E, SER93C, SER93E, THR15C, THR15E, TYR85E
• D-F: ALA57D, ALA57F, ALA62D, ALA62F, ALA6D, ALA6F, ARG61D, ARG61F, ARG89D, ARG89F, ARG91D, ARG91F, ASP14D, ASP14F, ASP60D, ASP60F, CYS17D, CYS17F, CYS70D, CYS70F, GLN10D, GLN10F, GLN68D, GLN68F, GLU13D, GLU13F, GLU7D, GLU7F, GLU92D, GLU92F, GLU96D, GLU96F, GLY20D, GLY20F, GLY88D, GLY88F, HIS86D, HIS86F, ILE12D, ILE12F, LEU16D, LEU16F, LEU63D, LEU63F, LEU67D, LEU67F, LEU8D, LEU8F, LEU94D, LEU94F, LEU97D, LEU97F, LYS11D, LYS11F, LYS4D, LYS4F, LYS64D, LYS64F, LYS9D, LYS9F, PHE19D, PHE19F, PHE21F, PHE66D, PHE66F, PRO18D, PRO18F, PRO3D, PRO3F, PRO65D, PRO65F, PRO95D, PRO95F, SER69D, SER69F, SER93D, SER93F, THR15D, THR15F, TYR85D, TYR85F, VAL90D, VAL90F
• E-F: ALA103E, ALA103F, ALA228E, ALA228F, ALA38E, ALA38F, ALA84F, ARG111E, ARG111F, ARG112E, ARG112F, ARG230E, ARG230F, ARG73E, ARG73F, ARG91E, ARG91F, ASN110E, ASN110F, ASP104E, ASP104F, ASP77E, ASP77F, ASP80E, ASP80F, GLN81E, GLN81F, GLN98E, GLN98F, GLU100E, GLU100F, GLU106E, GLU106F, HIS108E, HIS108F, HIS40E, HIS40F, HIS71E, HIS71F, ILE101E, ILE101F, ILE102E, ILE102F, ILE115E, ILE115F, ILE99E, ILE99F, LEU116F, LEU165E, LEU165F, LEU231E, LEU41E, LEU41F, LEU43E, LEU43F, LEU72E, LEU72F, LEU75E, LEU75F, LEU87F, LYS114E, LYS114F, PHE39E, PHE39F, PRO109E, PRO109F, PRO113E, PRO113F, PRO167E, PRO167F, PRO226E, PRO226F, PRO227E, PRO227F, PRO42E, PRO42F, PRO78E, PRO78F, THR76E, THR76F, TYR105E, TYR105F, TYR31E, TYR31F, VAL107E, VAL107F, VAL163E, VAL163F, VAL79E, VAL79F
• E-G: ALA137E, ALA137G, ALA38E, ALA38G, ARG111E, ARG111G, ARG112E, ARG112G, ARG132E, ARG132G, ARG144E, ARG144G, ASN110E, ASN110G, ASN142E, ASN142G, ASP138E, ASP138G, GLN133E, GLN133G, GLN143E, GLN143G, GLU106E, GLU106G, GLU136E, GLU136G, GLY141E, GLY141G, HIS108E, HIS108G, HIS40E, HIS40G, ILE115E, ILE115G, ILE145E, ILE145G, LEU116E, LEU116G, LEU35E, LEU35G, LEU41E, LEU41G, LYS114E, LYS114G, PHE39E, PHE39G, PRO109E, PRO109G, PRO113E, PRO113G, PRO139E, PRO139G, PRO36E, PRO36G, PRO37E, PRO37G, PRO42E, PRO42G, SER146E, SER146G, TRP140E, TRP140G, TYR31E, TYR31G, VAL107E, VAL107G, VAL135E, VAL135G
• E-H: ALA228E, ALA228H, ALA232E, ARG132E, ARG132H, ARG144E, ARG144H, ARG186H, ARG201E, ARG201H, ARG230E, ARG230H, ASN142E, ASN142H, ASN197E, ASN197H, ASP138E, ASP138H, ASP202E, ASP202H, GLN143E, GLN143H, GLN229E, GLN229H, GLU194E, GLU194H, GLY141E, GLY141H, HIS199E, HIS199H, ILE145E, ILE145H, ILE190E, ILE190H, LEU75E, LEU75H, PHE196E, PHE196H, PHE198E, PHE198H, PRO139E, PRO139H, PRO226E, PRO226H, PRO227E, PRO227H, SER224E, SER224H, THR225E, THR225H, TRP140E, TRP140H, TRP200E, TRP200H
• F-G: ALA228F, ALA228G, ARG132F, ARG132G, ARG144F, ARG144G, ARG186G, ARG201F, ARG201G, ARG230F, ARG230G, ASN142F, ASN142G, ASN197F, ASN197G, ASP138F, ASP138G, ASP202F, ASP202G, GLN143F, GLN143G, GLN229F, GLN229G, GLU194F, GLU194G, GLY141F, GLY141G, HIS199F, HIS199G, ILE145F, ILE145G, ILE190F, ILE190G, LEU75F, LEU75G, PHE196F, PHE198F, PHE198G, PRO139F, PRO139G, PRO226F, PRO226G, PRO227F, PRO227G, SER224F, SER224G, THR225F, THR225G, TRP140F, TRP140G, TRP200F, TRP200G
• F-H: ALA137F, ALA137H, ALA38F, ALA38H, ARG111F, ARG111H, ARG112F, ARG112H, ARG132F, ARG132H, ARG144F, ARG144H, ASN110F, ASN110H, ASN142F, ASN142H, ASP138F, ASP138H, GLN133F, GLN133H, GLN143F, GLN143H, GLU106H, GLU136F, GLU136H, GLY141F, GLY141H, HIS108F, HIS108H, HIS40F, HIS40H, ILE115F, ILE115H, ILE145F, ILE145H, LEU116F, LEU116H, LEU35F, LEU35H, LEU41F, LEU41H, LYS114F, LYS114H, PHE39F, PHE39H, PRO109F, PRO109H, PRO113F, PRO113H, PRO139F, PRO139H, PRO36F, PRO36H, PRO37F, PRO37H, PRO42F, PRO42H, SER146F, SER146H, TRP140F, TRP140H, TYR31F, TYR31H, VAL107F, VAL107H, VAL135F, VAL135H
• G-H: ALA103H, ALA228G, ALA228H, ALA38G, ALA38H, ALA84H, ARG111G, ARG111H, ARG112G, ARG112H, ARG230G, ARG230H, ARG73G, ARG73H, ARG91G, ARG91H, ASN110G, ASN110H, ASP104G, ASP104H, ASP77G, ASP77H, ASP80G, ASP80H, CYS70G, CYS70H, GLN229G, GLN229H, GLN81G, GLN81H, GLN98G, GLN98H, GLU100G, GLU100H, GLU106G, GLU106H, HIS108G, HIS108H, HIS40G, HIS40H, HIS71G, HIS71H, ILE101G, ILE101H, ILE102G, ILE102H, ILE115G, ILE115H, ILE99G, ILE99H, LEU165G, LEU165H, LEU41G, LEU41H, LEU43G, LEU43H, LEU72G, LEU72H, LEU75G, LEU75H, LYS114G, LYS114H, PHE39G, PHE39H, PRO109G, PRO109H, PRO113G, PRO113H, PRO226G, PRO226H, PRO227G, PRO227H, PRO42G, PRO42H, PRO78G, PRO78H, THR76G, THR76H, TYR105G, TYR105H, TYR31G, TYR31H, VAL107G, VAL107H, VAL163G, VAL163H, VAL79G, VAL79H
• G-I: ALA62G, ALA62I, ARG61G, ARG61I, ARG89G, ARG89I, ARG91G, ARG91I, ASP14G, ASP14I, ASP60G, ASP60I, CYS17G, CYS17I, CYS70G, CYS70I, CYS82G, CYS82I, GLN10G, GLN10I, GLN68G, GLN68I, GLN98G, GLN98I, GLU13G, GLU13I, GLU7G, GLU7I, GLU92G, GLU92I, GLU96G, GLU96I, GLY88G, GLY88I, HIS71G, HIS71I, HIS86G, HIS86I, LEU16G, LEU16I, LEU63G, LEU63I, LEU67G, LEU67I, LEU94G, LEU94I, LEU97G, LEU97I, LYS11G, LYS11I, LYS64G, LYS64I, PHE19G, PHE19I, PHE66G, PHE66I, PRO18G, PRO18I, PRO65G, PRO65I, PRO95G, PRO95I, SER69G, SER69I, SER93G, SER93I, THR15G, THR15I, TYR85G, TYR85I, VAL90G, VAL90I
• G-J: CYS70G, CYS70J
• H-I: CYS70H, CYS70I
• H-J: ALA62H, ALA62J, ARG61H, ARG61J, ARG89H, ARG89J, ARG91H, ARG91J, ASP14H, ASP14J, ASP60H, ASP60J, CYS17H, CYS17J, CYS70H, CYS70J, CYS82H, CYS82J, GLN10H, GLN10J, GLN68H, GLN68J, GLN98H, GLN98J, GLU13H, GLU13J, GLU7H, GLU7J, GLU92H, GLU92J, GLU96H, GLU96J, GLY20J, GLY88H, GLY88J, HIS71H, HIS71J, HIS86H, HIS86J, LEU16H, LEU16J, LEU63H, LEU63J, LEU67H, LEU67J, LEU94H, LEU94J, LEU97H, LEU97J, LYS11H, LYS11J, LYS4J, LYS64H, LYS64J, PHE19H, PHE19J, PHE66H, PHE66J, PRO18H, PRO18J, PRO65H, PRO65J, PRO95H, PRO95J, SER69H, SER69J, SER93H, SER93J, THR15H, THR15J, TYR85H, TYR85J, VAL90H, VAL90J
• I-J: ALA103I, ALA228I, ALA228J, ALA38I, ALA38J, ALA84I, ARG111I, ARG111J, ARG112I, ARG112J, ARG230I, ARG230J, ARG73I, ARG73J, ARG91I, ARG91J, ASN110I, ASN110J, ASP104I, ASP104J, ASP77I, ASP77J, ASP80I, ASP80J, CYS70I, CYS70J, GLN229I, GLN229J, GLN81I, GLN81J, GLN98I, GLN98J, GLU100I, GLU100J, GLU106I, GLU106J, GLY88I, GLY88J, HIS108I, HIS108J, HIS40I, HIS40J, HIS71I, HIS71J, ILE101I, ILE101J, ILE102I, ILE102J, ILE115I, ILE115J, ILE99I, ILE99J, LEU165I, LEU165J, LEU41I, LEU41J, LEU43I, LEU43J, LEU72I, LEU72J, LEU75I, LEU75J, LEU87I, LYS114I, LYS114J, PHE39I, PHE39J, PRO109I, PRO109J, PRO113I, PRO113J, PRO226I, PRO226J, PRO227I, PRO227J, PRO42I, PRO42J, PRO78I, PRO78J, THR76I, THR76J, TYR105I, TYR105J, TYR31I, TYR31J, VAL107I, VAL107J, VAL163I, VAL163J, VAL79I, VAL79J
• I-K: ALA137I, ALA137K, ALA38I, ALA38K, ARG111I, ARG111K, ARG112I, ARG112K, ARG132I, ARG132K, ARG144I, ARG144K, ASN110I, ASN110K, ASN142I, ASN142K, ASP138I, ASP138K, GLN133I, GLN133K, GLN143I, GLN143K, GLU106I, GLU136I, GLU136K, GLY141I, GLY141K, HIS108I, HIS108K, HIS40I, HIS40K, ILE115I, ILE115K, ILE145I, ILE145K, LEU116I, LEU116K, LEU35I, LEU35K, LEU41I, LEU41K, LYS114I, LYS114K, PHE39I, PHE39K, PRO109I, PRO109K, PRO113I, PRO113K, PRO139I, PRO139K, PRO36I, PRO36K, PRO37I, PRO37K, PRO42I, PRO42K, SER146I, SER146K, TRP140I, TRP140K, TYR31I, TYR31K, VAL107I, VAL107K, VAL135I, VAL135K
• I-L: ALA228I, ALA228L, ALA232L, ARG132I, ARG132L, ARG144I, ARG144L, ARG186I, ARG201I, ARG201L, ARG230I, ARG230L, ASN142I, ASN142L, ASN197I, ASN197L, ASP138I, ASP138L, ASP202I, ASP202L, GLN143I, GLN143L, GLN229I, GLN229L, GLU194I, GLU194L, GLY141I, GLY141L, HIS199I, HIS199L, ILE145I, ILE145L, ILE190I, ILE190L, LEU75I, LEU75L, PHE196I, PHE196L, PHE198I, PHE198L, PRO139I, PRO139L, PRO226I, PRO226L, PRO227I, PRO227L, SER224I, SER224L, THR225I, THR225L, TRP140I, TRP140L, TRP200I, TRP200L
• J-K: ALA228J, ALA228K, ARG132J, ARG132K, ARG144J, ARG144K, ARG201J, ARG201K, ARG230J, ARG230K, ASN142J, ASN142K, ASN197J, ASN197K, ASP138J, ASP138K, ASP202J, ASP202K, GLN143J, GLN143K, GLN229J, GLN229K, GLU194J, GLU194K, GLY141J, GLY141K, HIS199J, HIS199K, ILE145J, ILE145K, ILE190J, ILE190K, LEU75J, LEU75K, PHE196K, PHE198J, PHE198K, PRO139J, PRO139K, PRO226J, PRO226K, PRO227J, PRO227K, SER224J, SER224K, THR225J, THR225K, TRP140J, TRP140K, TRP200J, TRP200K
• J-L: ALA137J, ALA137L, ALA38J, ALA38L, ARG111J, ARG111L, ARG112J, ARG112L, ARG132J, ARG132L, ARG144J, ARG144L, ASN110J, ASN110L, ASN142J, ASN142L, ASP138J, ASP138L, GLN133J, GLN133L, GLN143J, GLN143L, GLU106J, GLU136J, GLU136L, GLY141J, GLY141L, HIS108J, HIS108L, HIS40J, HIS40L, ILE115J, ILE115L, ILE145J, ILE145L, LEU116J, LEU116L, LEU35J, LEU35L, LEU41J, LEU41L, LYS114J, LYS114L, PHE39J, PHE39L, PRO109J, PRO109L, PRO113J, PRO113L, PRO139J, PRO139L, PRO36J, PRO36L, PRO37J, PRO37L, PRO42J, PRO42L, SER146J, SER146L, TRP140J, TRP140L, TYR31J, TYR31L, VAL107J, VAL107L, VAL135J, VAL135L
• K-L: ALA228K, ALA228L, ALA38K, ALA38L, ARG111K, ARG111L, ARG112K, ARG112L, ARG230K, ARG230L, ARG73K, ARG73L, ARG91K, ARG91L, ASN110K, ASN110L, ASP104K, ASP104L, ASP77K, ASP77L, ASP80K, ASP80L, GLN81K, GLN81L, GLN98K, GLN98L, GLU100K, GLU100L, GLU106K, GLU106L, HIS108K, HIS108L, HIS40K, HIS40L, HIS71K, HIS71L, ILE101K, ILE101L, ILE102K, ILE102L, ILE115K, ILE115L, ILE99K, ILE99L, LEU165K, LEU165L, LEU231L, LEU41K, LEU41L, LEU43K, LEU43L, LEU72K, LEU72L, LEU75K, LEU75L, LYS114K, LYS114L, PHE39K, PHE39L, PRO109K, PRO109L, PRO113K, PRO113L, PRO167K, PRO167L, PRO226K, PRO226L, PRO227K, PRO227L, PRO42K, PRO42L, PRO78K, PRO78L, THR76K, THR76L, TYR105K, TYR105L, TYR31K, TYR31L, VAL107K, VAL107L, VAL163K, VAL163L, VAL79K, VAL79L
• K-N: ARG89K, ARG89N, ARG91K, ARG91N, GLU92K, GLU92N, GLU96K, GLU96N, LEU94K, LEU94N, PRO95K, PRO95N, SER93K, SER93N, THR15K, THR15N, TYR85K, TYR85N
• L-M: ALA57L, ALA57M, ALA62L, ALA62M, ALA6L, ALA6M, ARG61L, ARG61M, ARG89L, ARG89M, ARG91L, ARG91M, ASP14L, ASP14M, ASP60L, ASP60M, CYS17L, CYS17M, CYS70L, CYS70M, GLN10L, GLN10M, GLN68L, GLN68M, GLU13L, GLU13M, GLU7L, GLU7M, GLU92L, GLU92M, GLU96L, GLU96M, GLY20L, GLY20M, GLY88L, GLY88M, HIS71L, HIS86L, HIS86M, ILE12L, ILE12M, LEU16L, LEU16M, LEU63L, LEU63M, LEU67L, LEU67M, LEU8L, LEU8M, LEU94L, LEU94M, LEU97L, LEU97M, LYS11L, LYS11M, LYS4L, LYS4M, LYS64L, LYS64M, LYS9L, LYS9M, PHE19L, PHE19M, PHE21M, PHE66L, PHE66M, PRO18L, PRO18M, PRO3L, PRO3M, PRO65L, PRO65M, PRO95L, PRO95M, SER69L, SER69M, SER93L, SER93M, THR15L, THR15M, TYR85L, TYR85M, VAL5L, VAL90L, VAL90M
• M-N: ALA103M, ALA228M, ALA228N, ALA38M, ALA38N, ALA84M, ARG111M, ARG111N, ARG112M, ARG112N, ARG230M, ARG230N, ARG73M, ARG73N, ARG91M, ARG91N, ASN110M, ASN110N, ASP104M, ASP104N, ASP77M, ASP77N, ASP80M, ASP80N, GLN81M, GLN81N, GLN98M, GLN98N, GLU100M, GLU100N, GLU106M, GLU106N, HIS108M, HIS108N, HIS40M, HIS40N, HIS71M, HIS71N, ILE101M, ILE101N, ILE102M, ILE102N, ILE115M, ILE115N, ILE99M, ILE99N, LEU116M, LEU165M, LEU165N, LEU231M, LEU231N, LEU41M, LEU41N, LEU43M, LEU43N, LEU72M, LEU72N, LEU75M, LEU75N, LEU87M, LYS114M, LYS114N, PHE39M, PHE39N, PRO109M, PRO109N, PRO113M, PRO113N, PRO167M, PRO167N, PRO226M, PRO226N, PRO227M, PRO227N, PRO42M, PRO42N, PRO78M, THR76M, THR76N, TYR105M, TYR105N, TYR31M, TYR31N, VAL107M, VAL107N, VAL163M, VAL163N, VAL79M, VAL79N
• M-O: ALA137M, ALA137O, ALA38M, ALA38O, ARG111M, ARG111O, ARG112M, ARG112O, ARG132M, ARG132O, ARG144M, ARG144O, ASN110M, ASN110O, ASN142M, ASN142O, ASP138M, ASP138O, GLN133M, GLN133O, GLN143M, GLN143O, GLU106M, GLU106O, GLU136M, GLU136O, GLY141M, GLY141O, HIS108M, HIS108O, HIS40M, HIS40O, ILE115M, ILE115O, ILE145M, ILE145O, LEU116M, LEU116O, LEU35M, LEU35O, LEU41M, LEU41O, LYS114M, LYS114O, PHE39M, PHE39O, PRO109M, PRO109O, PRO113M, PRO113O, PRO139M, PRO139O, PRO36M, PRO36O, PRO37M, PRO37O, PRO42M, PRO42O, SER146M, SER146O, TRP140M, TRP140O, TYR31M, TYR31O, VAL107M, VAL107O, VAL135M, VAL135O
• M-P: ALA228M, ALA228P, ALA232M, ARG132M, ARG132P, ARG144M, ARG144P, ARG186P, ARG201M, ARG201P, ARG230M, ARG230P, ASN142M, ASN142P, ASN197M, ASN197P, ASP138M, ASP138P, ASP202M, ASP202P, GLN143M, GLN143P, GLN229M, GLN229P, GLU194M, GLU194P, GLY141M, GLY141P, HIS199M, HIS199P, ILE145M, ILE145P, ILE190M, ILE190P, LEU75M, LEU75P, PHE196M, PHE196P, PHE198M, PHE198P, PRO139M, PRO139P, PRO226M, PRO226P, PRO227M, PRO227P, SER224M, SER224P, THR225M, THR225P, TRP140M, TRP140P, TRP200M, TRP200P
• N-O: ALA228N, ALA228O, ALA232N, ARG132N, ARG132O, ARG144N, ARG144O, ARG201N, ARG201O, ARG230N, ARG230O, ASN142N, ASN142O, ASN197N, ASN197O, ASP138N, ASP138O, ASP202N, ASP202O, GLN143N, GLN143O, GLN229N, GLN229O, GLU194N, GLU194O, GLY141N, GLY141O, HIS199N, HIS199O, ILE145N, ILE145O, ILE190N, ILE190O, LEU75N, LEU75O, PHE196N, PHE196O, PHE198N, PHE198O, PRO139N, PRO139O, PRO226N, PRO226O, PRO227N, PRO227O, SER224N, SER224O, THR225N, THR225O, TRP140N, TRP140O, TRP200N, TRP200O
• N-P: ALA137N, ALA137P, ALA38N, ALA38P, ARG111N, ARG111P, ARG112N, ARG112P, ARG132N, ARG132P, ARG144N, ARG144P, ASN110N, ASN110P, ASN142N, ASN142P, ASP138N, ASP138P, GLN133N, GLN133P, GLN143N, GLN143P, GLU106N, GLU106P, GLU136N, GLU136P, GLY141N, GLY141P, HIS108N, HIS108P, HIS40N, HIS40P, ILE115N, ILE115P, ILE145N, ILE145P, LEU116N, LEU116P, LEU35N, LEU35P, LEU41N, LEU41P, LYS114N, LYS114P, PHE39N, PHE39P, PRO109N, PRO109P, PRO113N, PRO113P, PRO139N, PRO139P, PRO36N, PRO36P, PRO37N, PRO37P, PRO42N, PRO42P, SER146N, SER146P, TRP140N, TRP140P, TYR31N, TYR31P, VAL107N, VAL107P, VAL135N, VAL135P
• O-P: ALA228O, ALA228P, ALA38O, ALA38P, ARG111O, ARG111P, ARG112O, ARG112P, ARG230O, ARG230P, ARG73O, ARG73P, ARG91O, ARG91P, ASN110O, ASN110P, ASP104O, ASP104P, ASP77O, ASP77P, ASP80O, ASP80P, CYS70O, CYS70P, GLN229P, GLN81O, GLN81P, GLN98O, GLN98P, GLU100O, GLU100P, GLU106O, GLU106P, HIS108O, HIS108P, HIS40O, HIS40P, HIS71O, HIS71P, ILE101O, ILE101P, ILE102O, ILE102P, ILE115O, ILE115P, ILE99O, ILE99P, LEU116O, LEU165O, LEU165P, LEU231O, LEU231P, LEU41O, LEU41P, LEU43O, LEU43P, LEU72O, LEU72P, LEU75O, LEU75P, LYS114O, LYS114P, PHE39O, PHE39P, PRO109O, PRO109P, PRO113O, PRO113P, PRO226O, PRO226P, PRO227O, PRO227P, PRO42O, PRO42P, PRO78O, PRO78P, THR76O, THR76P, TYR105O, TYR105P, TYR31O, TYR31P, VAL107O, VAL107P, VAL163O, VAL163P, VAL79O, VAL79P