3SLL

crystal structure of a probable enoyl-coa hydratase/isomerase from mycobacterium abscessus

• Total interactions analyzed: 15
• Total true interactions: 15
• Strongest Interaction:
  • Chains: D-E
  • Int. Res.: 168
  • Norm. En. per Res.: -4.3879
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-110.1659	-27.2107	-565.863	-703.2395	172	29	13	22538	6	45	36
A-C	-122.5797	-33.8559	-557.411	-713.8466	167	24	15	22046	3	42	36
A-D	-59.0466	-105.1247	-285.144	-449.3153	127	12	1	11662	12	54	39
A-E	-14.6721	-45.9197	-208.213	-268.8048	71	2	11	8375	6	22	27
A-F	0.0	13.9725	-8.8154	5.1571	16	0	1	444	0	4	1
B-C	-114.9822	-32.7532	-564.59	-712.3253	173	26	14	22400	5	44	36
B-D	-8.5632	-39.9518	-209.317	-257.8319	72	3	9	8462	5	22	27
B-E	0.0	12.9878	12.3021	25.2899	16	3	1	471	0	4	1
B-F	-64.255	-94.3279	-273.067	-431.6499	122	12	1	10821	12	52	41
C-D	0.0	12.722	-7.0715	5.6505	16	0	1	414	0	4	1
C-E	-62.9303	-98.9763	-267.906	-429.8126	126	7	1	11089	12	58	42
C-F	-9.0809	7.7176	-207.441	-208.8043	73	5	9	8343	6	22	29
D-E	-145.4954	-30.3156	-561.362	-737.173	168	22	14	22075	5	44	36
D-F	-141.6369	-23.2654	-553.643	-718.5453	171	23	14	22334	2	44	36
E-F	-126.3203	-29.7613	-555.323	-711.4045	169	27	15	22158	6	47	37

Interface residues

• A-B: ALA121B, ALA123A, ALA137A, ALA138A, ALA146A, ALA158B, ALA164A, ALA179B, ALA200B, ALA206B, ALA226A, ALA226B, ALA227A, ALA227B, ALA253B, ALA256B, ALA263B, ALA26A, ALA50B, ALA84A, ARG100A, ARG127B, ARG136A, ARG157A, ARG157B, ARG163A, ARG163B, ARG172A, ARG181A, ARG181B, ARG187B, ARG204B, ARG210B, ARG218B, ARG244B, ARG257B, ARG266B, ARG269B, ARG49B, ARG86A, ARG99A, ASN141A, ASN142A, ASN249B, ASP125B, ASP166A, ASP173A, ASP177B, ASP225A, ASP225B, ASP248B, ASP267B, ASP92A, CYS119A, CYS124B, GLN103B, GLN235B, GLN240B, GLN80A, GLU148A, GLU178A, GLU178B, GLU180B, GLU197B, GLU203B, GLU214B, GLU230B, GLU236B, GLU251B, GLU252B, GLU89A, GLU93A, GLY115A, GLY116A, GLY139A, GLY143A, GLY150A, GLY160A, GLY160B, GLY171A, GLY183B, GLY202B, GLY207B, GLY212B, GLY223B, GLY237B, GLY239B, GLY63A, HIS232B, HIS234B, ILE106B, ILE140A, ILE159A, ILE159B, ILE167A, ILE182A, ILE182B, ILE201B, ILE205B, ILE213B, ILE220B, ILE83A, ILE95A, LEU122A, LEU122B, LEU144A, LEU149A, LEU151A, LEU154A, LEU154B, LEU155A, LEU155B, LEU169A, LEU184B, LEU215B, LEU224A, LEU224B, LEU229B, LEU238B, LEU241B, LEU245B, LEU246B, LEU85A, LEU91A, LEU96A, LYS188B, LYS217B, MET168A, MET233B, MET88A, PHE208B, PHE250B, PHE265B, PHE29A, PRO104B, PRO156A, PRO156B, PRO211B, PRO81A, SER147A, SER152A, SER162A, SER165A, SER186B, SER209B, SER222A, SER222B, SER228B, SER231B, SER87A, THR145A, THR161A, THR170A, THR216B, THR219B, THR247B, THR254B, THR79A, THR82A, THR97A, TRP221A, TRP221B, TYR153A, TYR153B, TYR242B, VAL105B, VAL126B, VAL128B, VAL174A, VAL185B, VAL243B, VAL94A
• A-C: ALA121A, ALA123C, ALA137C, ALA138C, ALA146C, ALA158A, ALA164C, ALA179A, ALA200A, ALA206A, ALA226A, ALA226C, ALA227A, ALA227C, ALA253A, ALA256A, ALA263A, ALA50A, ALA84C, ARG100C, ARG127A, ARG136C, ARG157A, ARG157C, ARG163A, ARG163C, ARG172C, ARG181A, ARG181C, ARG187A, ARG204A, ARG210A, ARG218A, ARG244A, ARG269A, ARG49A, ARG86C, ARG99C, ASN141C, ASN142C, ASN249A, ASP125A, ASP166C, ASP173C, ASP177A, ASP225A, ASP225C, ASP248A, ASP267A, ASP92C, CYS119C, CYS124A, GLN103A, GLN235A, GLN240A, GLN80C, GLU148C, GLU178A, GLU178C, GLU180A, GLU197A, GLU214A, GLU230A, GLU236A, GLU251A, GLU252A, GLU89C, GLU93C, GLY115C, GLY116C, GLY139C, GLY143C, GLY150C, GLY160A, GLY160C, GLY171C, GLY183A, GLY202A, GLY207A, GLY212A, GLY223A, GLY237A, GLY239A, HIS102A, HIS232A, HIS234A, ILE106A, ILE140C, ILE159A, ILE159C, ILE167C, ILE182A, ILE182C, ILE201A, ILE205A, ILE213A, ILE220A, ILE83C, ILE95C, LEU122A, LEU122C, LEU144C, LEU149C, LEU151C, LEU154A, LEU154C, LEU155A, LEU155C, LEU169C, LEU184A, LEU215A, LEU224A, LEU224C, LEU229A, LEU238A, LEU241A, LEU245A, LEU246A, LEU85C, LEU91C, LEU96C, LYS188A, LYS217A, MET168C, MET233A, MET88C, PHE208A, PHE250A, PHE265A, PHE29C, PRO104A, PRO156A, PRO156C, PRO211A, PRO81C, SER147C, SER152C, SER162C, SER165C, SER186A, SER209A, SER222A, SER222C, SER228A, SER231A, SER87C, THR145C, THR161C, THR170C, THR216A, THR219A, THR247A, THR254A, THR79C, THR82C, THR97C, TRP221A, TRP221C, TYR153A, TYR153C, TYR242A, VAL105A, VAL126A, VAL128A, VAL185A, VAL243A, VAL94C
• A-D: ALA227A, ALA227D, ALA84A, ALA84D, ARG100A, ARG100D, ARG210A, ARG210D, ARG218A, ARG218D, ARG266A, ARG266D, ARG269A, ARG269D, ARG49A, ARG49D, ARG86A, ARG86D, ARG99A, ARG99D, ASN249A, ASN249D, ASN46A, ASN46D, ASP225A, ASP225D, ASP248A, ASP248D, ASP267A, ASP267D, ASP41A, ASP41D, ASP45A, ASP45D, ASP47A, ASP47D, ASP92A, ASP92D, GLN103A, GLN103D, GLN37A, GLN37D, GLN80A, GLN80D, GLU214A, GLU214D, GLU89A, GLU89D, GLU93A, GLU93D, GLY212A, GLY212D, GLY239A, GLY239D, GLY76A, GLY76D, GLY77A, GLY77D, HIS102A, HIS102D, HIS44A, HIS44D, HIS74A, HIS74D, ILE213A, ILE42A, ILE72D, ILE75A, ILE75D, ILE83A, ILE83D, LEU215A, LEU215D, LEU238A, LEU238D, LEU245A, LEU245D, LEU246A, LEU246D, LEU33D, LEU78A, LEU78D, LEU85A, LEU85D, LEU90A, LEU90D, LEU96A, LEU96D, LYS268A, LYS268D, LYS36A, LYS36D, MET101A, MET101D, MET88A, MET88D, PHE265A, PHE265D, PRO211A, PRO211D, PRO73A, PRO73D, PRO81A, PRO81D, SER209A, SER209D, SER43A, SER43D, SER87A, THR145A, THR145D, THR247A, THR247D, THR79A, THR79D, THR82A, THR82D, THR97A, THR97D, TYR242A, TYR242D, VAL243A, VAL243D, VAL40A, VAL40D, VAL48A, VAL48D
• A-E: ALA226A, ALA226E, ALA227A, ALA227E, ARG100A, ARG100E, ARG218A, ARG218E, ARG244A, ARG244E, ARG269A, ARG269E, ARG99A, ARG99E, ASP225A, ASP225E, GLN235A, GLN235E, GLN240A, GLN240E, GLU230A, GLU230E, GLU236A, GLU236E, GLY223A, GLY223E, GLY237A, GLY237E, GLY239A, GLY239E, HIS232A, HIS232E, HIS234A, HIS234E, LEU215A, LEU215E, LEU224A, LEU224E, LEU229A, LEU229E, LEU238A, LEU238E, LEU241A, LEU241E, LEU245A, LEU245E, LEU246A, LEU246E, LEU96A, LEU96E, MET233A, MET233E, PRO211A, SER222A, SER222E, SER228A, SER228E, SER231A, SER231E, THR219A, THR219E, THR247A, THR247E, TRP221A, TRP221E, TYR153A, TYR153E, TYR242A, TYR242E, VAL243A, VAL243E
• A-F: ALA226A, ALA226F, ALA227A, ALA227F, GLU230A, GLU230F, LEU229A, LEU229F, LEU85A, LEU85F, SER228A, SER228F, SER231A, SER231F, THR145A, THR145F
• B-C: ALA121C, ALA123B, ALA137B, ALA138B, ALA146B, ALA158C, ALA164B, ALA179C, ALA200C, ALA206C, ALA226B, ALA226C, ALA227B, ALA227C, ALA253C, ALA256C, ALA263C, ALA26B, ALA50C, ALA69B, ALA84B, ARG100B, ARG127C, ARG136B, ARG157B, ARG157C, ARG163B, ARG163C, ARG172B, ARG181B, ARG181C, ARG187C, ARG204C, ARG210C, ARG218C, ARG244C, ARG257C, ARG266C, ARG269C, ARG49C, ARG86B, ARG99B, ASN141B, ASN142B, ASN249C, ASP125C, ASP166B, ASP173B, ASP177C, ASP225B, ASP225C, ASP248C, ASP267C, ASP92B, CYS119B, CYS124C, GLN103C, GLN235C, GLN240C, GLN80B, GLU148B, GLU178B, GLU178C, GLU180C, GLU214C, GLU230C, GLU236C, GLU251C, GLU252C, GLU89B, GLU93B, GLY115B, GLY116B, GLY139B, GLY143B, GLY150B, GLY160B, GLY160C, GLY171B, GLY183C, GLY202C, GLY207C, GLY212C, GLY223B, GLY223C, GLY237C, GLY239C, HIS232C, HIS234C, ILE106C, ILE114B, ILE140B, ILE159B, ILE159C, ILE167B, ILE182B, ILE182C, ILE201C, ILE205C, ILE213C, ILE220C, ILE83B, ILE95B, LEU122B, LEU122C, LEU144B, LEU149B, LEU151B, LEU154B, LEU154C, LEU155B, LEU155C, LEU169B, LEU184C, LEU215C, LEU224B, LEU224C, LEU229C, LEU238C, LEU241C, LEU245C, LEU246C, LEU85B, LEU91B, LEU96B, LYS188C, LYS217C, MET168B, MET233C, MET88B, PHE208C, PHE250C, PHE265C, PHE29B, PRO104C, PRO156B, PRO156C, PRO211C, PRO81B, SER147B, SER152B, SER162B, SER165B, SER186C, SER209C, SER222B, SER222C, SER228B, SER228C, SER231C, SER87B, THR145B, THR161B, THR170B, THR216C, THR219C, THR247C, THR254C, THR79B, THR82B, THR97B, TRP221B, TRP221C, TYR153B, TYR153C, TYR242C, VAL105C, VAL126C, VAL128C, VAL174B, VAL185C, VAL243C, VAL94B
• B-D: ALA226B, ALA226D, ALA227B, ALA227D, ARG100B, ARG100D, ARG218B, ARG218D, ARG244B, ARG244D, ARG269B, ARG269D, ARG99B, ARG99D, ASP225B, ASP225D, GLN235B, GLN235D, GLN240B, GLN240D, GLU230B, GLU230D, GLU236B, GLU236D, GLY223B, GLY223D, GLY237B, GLY237D, GLY239B, GLY239D, HIS232B, HIS232D, HIS234B, HIS234D, LEU215B, LEU215D, LEU224B, LEU224D, LEU229B, LEU229D, LEU238B, LEU238D, LEU241B, LEU241D, LEU245B, LEU245D, LEU246B, LEU246D, LEU96B, LEU96D, MET233B, MET233D, PRO211B, PRO211D, SER222B, SER222D, SER228B, SER228D, SER231B, SER231D, THR219B, THR219D, THR247B, THR247D, TRP221B, TRP221D, TYR153B, TYR153D, TYR242B, TYR242D, VAL243B, VAL243D
• B-E: ALA226B, ALA226E, ALA227B, ALA227E, GLU230B, GLU230E, LEU229B, LEU229E, LEU85B, LEU85E, SER228B, SER228E, SER231B, SER231E, THR145B, THR145E
• B-F: ALA227B, ALA227F, ALA84B, ALA84F, ARG100B, ARG100F, ARG210B, ARG210F, ARG218B, ARG218F, ARG266B, ARG266F, ARG269B, ARG269F, ARG49B, ARG49F, ARG86B, ARG86F, ARG99B, ARG99F, ASN249B, ASN249F, ASN46B, ASN46F, ASP225B, ASP225F, ASP248B, ASP248F, ASP267B, ASP267F, ASP41B, ASP41F, ASP45B, ASP45F, ASP47B, ASP47F, ASP92B, ASP92F, GLN103B, GLN103F, GLN80B, GLN80F, GLU214B, GLU214F, GLU89B, GLU89F, GLU93B, GLU93F, GLY212B, GLY212F, GLY239B, GLY239F, GLY76B, GLY76F, GLY77B, GLY77F, HIS102B, HIS102F, HIS44B, HIS44F, HIS74B, HIS74F, ILE42F, ILE75B, ILE75F, ILE83B, ILE83F, LEU215B, LEU215F, LEU238B, LEU238F, LEU245B, LEU245F, LEU246B, LEU246F, LEU33F, LEU78B, LEU78F, LEU85B, LEU85F, LEU90B, LEU90F, LEU96B, LEU96F, LYS268B, LYS268F, LYS36F, MET101B, MET101F, MET88B, MET88F, PHE265B, PHE265F, PRO211B, PRO211F, PRO73B, PRO73F, PRO81B, PRO81F, SER209B, SER209F, SER43B, SER43F, SER87B, THR145B, THR145F, THR247B, THR247F, THR79B, THR79F, THR82B, THR82F, THR97B, THR97F, TYR242B, TYR242F, VAL243B, VAL243F, VAL40B, VAL40F, VAL48B, VAL48F
• C-D: ALA226C, ALA226D, ALA227C, ALA227D, GLU230C, GLU230D, LEU229C, LEU229D, LEU85C, LEU85D, SER228C, SER228D, SER231C, SER231D, THR145C, THR145D
• C-E: ALA227C, ALA227E, ALA84C, ALA84E, ARG100C, ARG100E, ARG210C, ARG210E, ARG218C, ARG218E, ARG266C, ARG266E, ARG269C, ARG269E, ARG49C, ARG49E, ARG86C, ARG86E, ARG99C, ARG99E, ASN249C, ASN249E, ASN46C, ASN46E, ASP225C, ASP225E, ASP248C, ASP248E, ASP267C, ASP267E, ASP41C, ASP41E, ASP45C, ASP45E, ASP47C, ASP47E, ASP92C, ASP92E, GLN103C, GLN103E, GLN37C, GLN37E, GLN80C, GLN80E, GLU214C, GLU214E, GLU89C, GLU89E, GLU93C, GLU93E, GLY212C, GLY212E, GLY239C, GLY239E, GLY76C, GLY76E, GLY77C, GLY77E, HIS102C, HIS102E, HIS44C, HIS44E, HIS74C, HIS74E, ILE42E, ILE72E, ILE75C, ILE75E, ILE83C, ILE83E, LEU215C, LEU215E, LEU238C, LEU238E, LEU245C, LEU245E, LEU246C, LEU246E, LEU33E, LEU78C, LEU78E, LEU85C, LEU85E, LEU90C, LEU90E, LEU96C, LEU96E, LYS268C, LYS268E, LYS36C, LYS36E, MET101C, MET101E, MET88C, MET88E, PHE265C, PHE265E, PRO211C, PRO211E, PRO73C, PRO73E, PRO81C, PRO81E, SER209C, SER209E, SER43C, SER43E, SER87C, THR145C, THR145E, THR247C, THR247E, THR79C, THR79E, THR82C, THR82E, THR97C, THR97E, TYR242C, TYR242E, VAL243C, VAL243E, VAL40C, VAL40E, VAL48C, VAL48E
• C-F: ALA226C, ALA226F, ALA227C, ALA227F, ARG100C, ARG100F, ARG218C, ARG218F, ARG244C, ARG244F, ARG269C, ARG269F, ARG99C, ARG99F, ASP225C, ASP225F, GLN235C, GLN235F, GLN240C, GLN240F, GLU230C, GLU230F, GLU236C, GLU236F, GLY223C, GLY223F, GLY237C, GLY237F, GLY239C, GLY239F, HIS232C, HIS232F, HIS234C, HIS234F, LEU215C, LEU215F, LEU224C, LEU224F, LEU229C, LEU229F, LEU238C, LEU238F, LEU241C, LEU241F, LEU245C, LEU245F, LEU246C, LEU246F, LEU96C, LEU96F, LYS217C, MET233C, MET233F, PRO211C, PRO211F, SER222C, SER222F, SER228C, SER228F, SER231C, SER231F, THR219C, THR219F, THR247C, THR247F, TRP221C, TRP221F, TYR153C, TYR153F, TYR242C, TYR242F, VAL243C, VAL243F
• D-E: ALA123D, ALA137D, ALA138D, ALA146D, ALA158E, ALA164D, ALA179E, ALA200E, ALA206E, ALA226D, ALA226E, ALA227D, ALA227E, ALA253E, ALA256E, ALA263E, ALA50E, ALA84D, ARG100D, ARG127E, ARG136D, ARG157D, ARG157E, ARG163D, ARG163E, ARG172D, ARG181D, ARG181E, ARG187E, ARG204E, ARG210E, ARG218E, ARG244E, ARG257E, ARG266E, ARG269E, ARG49E, ARG86D, ARG99D, ASN141D, ASN142D, ASN249E, ASP125E, ASP166D, ASP173D, ASP177E, ASP225D, ASP225E, ASP248E, ASP267E, ASP92D, CYS119D, CYS124E, GLN103E, GLN235E, GLN240E, GLN80D, GLU148D, GLU178D, GLU178E, GLU180E, GLU197E, GLU203E, GLU214E, GLU230E, GLU236E, GLU251E, GLU252E, GLU89D, GLU93D, GLY115D, GLY116D, GLY139D, GLY143D, GLY150D, GLY160D, GLY160E, GLY171D, GLY183E, GLY202E, GLY207E, GLY212E, GLY223E, GLY237E, GLY239E, HIS232E, HIS234E, ILE106E, ILE140D, ILE159D, ILE159E, ILE167D, ILE182D, ILE182E, ILE201E, ILE205E, ILE213E, ILE220E, ILE83D, ILE95D, LEU122D, LEU122E, LEU144D, LEU149D, LEU151D, LEU154D, LEU154E, LEU155D, LEU155E, LEU169D, LEU184E, LEU215E, LEU224D, LEU224E, LEU229E, LEU238E, LEU241E, LEU245E, LEU246E, LEU85D, LEU91D, LEU96D, LYS217E, MET168D, MET233E, MET27D, MET88D, PHE208E, PHE250E, PHE265E, PHE29D, PRO104E, PRO156D, PRO156E, PRO211E, PRO81D, SER147D, SER152D, SER162D, SER165D, SER186E, SER209E, SER222D, SER222E, SER228E, SER231E, SER87D, THR145D, THR161D, THR170D, THR216E, THR219E, THR247E, THR254E, THR79D, THR82D, THR97D, TRP221D, TRP221E, TYR153D, TYR153E, TYR242E, VAL105E, VAL126E, VAL128E, VAL185E, VAL243E, VAL94D
• D-F: ALA123F, ALA137F, ALA138F, ALA146F, ALA158D, ALA164F, ALA179D, ALA200D, ALA206D, ALA226D, ALA226F, ALA227D, ALA227F, ALA253D, ALA256D, ALA263D, ALA26F, ALA84F, ARG100F, ARG127D, ARG136F, ARG157D, ARG157F, ARG163D, ARG163F, ARG172F, ARG181D, ARG181F, ARG187D, ARG204D, ARG210D, ARG218D, ARG244D, ARG257D, ARG266D, ARG269D, ARG49D, ARG86F, ARG99F, ASN141F, ASN142F, ASN249D, ASP125D, ASP166F, ASP173F, ASP177D, ASP225D, ASP225F, ASP248D, ASP267D, ASP92F, CYS119F, CYS124D, GLN103D, GLN235D, GLN240D, GLN80F, GLU148F, GLU178D, GLU178F, GLU180D, GLU197D, GLU203D, GLU214D, GLU230D, GLU236D, GLU251D, GLU252D, GLU89F, GLU93F, GLY115F, GLY116F, GLY139F, GLY143F, GLY150F, GLY160D, GLY160F, GLY171F, GLY183D, GLY202D, GLY207D, GLY212D, GLY223D, GLY237D, GLY239D, GLY63F, HIS102D, HIS232D, HIS234D, ILE106D, ILE114F, ILE140F, ILE159D, ILE159F, ILE167F, ILE182D, ILE182F, ILE201D, ILE205D, ILE213D, ILE220D, ILE83F, ILE95F, LEU122D, LEU122F, LEU144F, LEU149F, LEU151F, LEU154D, LEU154F, LEU155D, LEU155F, LEU169F, LEU184D, LEU215D, LEU224D, LEU224F, LEU229D, LEU238D, LEU241D, LEU245D, LEU246D, LEU85F, LEU91F, LEU96F, LYS217D, MET168F, MET233D, MET88F, PHE208D, PHE250D, PHE265D, PHE29F, PRO104D, PRO156D, PRO156F, PRO211D, PRO81F, SER147F, SER152F, SER162F, SER165F, SER186D, SER209D, SER222D, SER222F, SER228D, SER228F, SER231D, SER87F, THR145F, THR161F, THR170F, THR216D, THR219D, THR247D, THR254D, THR82F, THR97F, TRP221D, TRP221F, TYR153D, TYR153F, TYR242D, VAL105D, VAL126D, VAL128D, VAL174F, VAL185D, VAL243D, VAL94F
• E-F: ALA123E, ALA137E, ALA138E, ALA146E, ALA158F, ALA164E, ALA179F, ALA200F, ALA206F, ALA226E, ALA226F, ALA227E, ALA227F, ALA253F, ALA256F, ALA263F, ALA64E, ALA84E, ARG100E, ARG127F, ARG136E, ARG157E, ARG157F, ARG163E, ARG163F, ARG172E, ARG181E, ARG181F, ARG187F, ARG204F, ARG210F, ARG218F, ARG244F, ARG257F, ARG266F, ARG49F, ARG86E, ARG99E, ASN141E, ASN142E, ASN249F, ASP125F, ASP166E, ASP173E, ASP177F, ASP225E, ASP225F, ASP248F, ASP267F, ASP65E, ASP92E, CYS119E, CYS124F, GLN103F, GLN235F, GLN240F, GLN80E, GLU148E, GLU178E, GLU178F, GLU180F, GLU203F, GLU214F, GLU230F, GLU236F, GLU251F, GLU252F, GLU89E, GLU93E, GLY115E, GLY116E, GLY139E, GLY143E, GLY150E, GLY160E, GLY160F, GLY171E, GLY183F, GLY202F, GLY207F, GLY212F, GLY223E, GLY223F, GLY237F, GLY239F, HIS232F, HIS234F, ILE106F, ILE140E, ILE159E, ILE159F, ILE167E, ILE182E, ILE182F, ILE201F, ILE205F, ILE213F, ILE220F, ILE83E, ILE95E, LEU122E, LEU122F, LEU144E, LEU149E, LEU151E, LEU154E, LEU154F, LEU155E, LEU155F, LEU169E, LEU184F, LEU215F, LEU224E, LEU224F, LEU229F, LEU238F, LEU241F, LEU245F, LEU246F, LEU85E, LEU91E, LEU96E, LYS188F, LYS217F, MET168E, MET233F, MET88E, PHE208F, PHE250F, PHE265F, PHE29E, PRO104F, PRO156E, PRO156F, PRO211F, PRO81E, SER147E, SER152E, SER162E, SER165E, SER186F, SER209F, SER222E, SER222F, SER228E, SER228F, SER231F, SER87E, THR145E, THR161E, THR170E, THR216F, THR219F, THR247F, THR254F, THR79E, THR82E, THR97E, TRP221E, TRP221F, TYR153E, TYR153F, TYR242F, VAL105F, VAL126F, VAL128F, VAL185F, VAL243F, VAL94E