3SKU

herpes simplex virus glycoprotein d bound to the human receptor nectin-1

• Total interactions analyzed: 15
• Total true interactions: 4
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 109
  • Norm. En. per Res.: -2.2248
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-D	-21.0629	0.0	-136.959	-158.0219	97	49	1	8609	3	12	9
B-F	-35.7402	0.0	-141.528	-177.2682	91	33	1	7631	2	12	9
C-E	-10.966	0.0	-165.762	-176.728	97	17	0	7890	2	11	8
E-F	-19.3393	-20.0022	-203.162	-242.5036	109	23	4	9380	3	25	24

Interface residues

• A-D: ALA127D, ALA201A, ALA232A, ALA79D, ALA91D, ARG134A, ARG134D, ARG196A, ARG222A, ARG35A, ARG36A, ASN133D, ASN136A, ASN227A, ASN72D, ASN77D, ASN82D, ASP139A, ASP215A, ASP26A, CYS202A, GLN132A, GLN228A, GLN27A, GLN64D, GLN68D, GLN76D, GLU125D, GLU135D, GLY132D, GLY218A, GLY73D, GLY86D, HIS39A, ILE123D, ILE197A, ILE217A, ILE224A, ILE238A, ILE62D, ILE80D, LEU203A, LEU220A, LEU236A, LEU25A, LEU28A, LEU90D, LYS61D, LYS69D, LYS75D, MET219A, MET85D, PHE126D, PHE129D, PHE223A, PRO130D, PRO133A, PRO198A, PRO199A, PRO221A, PRO23A, PRO58D, PRO83D, PRO92D, SER140A, SER200A, SER216A, SER235A, SER59D, SER70D, SER74D, SER84D, SER88D, THR128D, THR131D, THR213A, THR230A, THR29A, THR63D, THR66D, THR71D, TRP135A, TRP67D, TYR137A, TYR234A, TYR38A, TYR81D, VAL214A, VAL231A, VAL233A, VAL24A, VAL37A, VAL60D, VAL65D, VAL78D, VAL87D, VAL89D
• B-F: ALA127F, ALA201B, ALA232B, ALA79F, ALA91F, ARG134B, ARG134F, ARG196B, ARG222B, ARG35B, ARG36B, ASN133F, ASN136B, ASN227B, ASN72F, ASN77F, ASN82F, ASP139B, ASP215B, ASP30B, CYS202B, GLN132B, GLN228B, GLN64F, GLN68F, GLN76F, GLU125F, GLU135F, GLY132F, GLY218B, GLY73F, GLY86F, HIS39B, ILE123F, ILE197B, ILE217B, ILE224B, ILE238B, ILE62F, ILE80F, LEU203B, LEU220B, LEU236B, LEU28B, LEU90F, LYS237B, LYS61F, LYS69F, LYS75F, MET219B, MET85F, PHE126F, PHE129F, PHE223B, PRO130F, PRO133B, PRO198B, PRO199B, PRO221B, PRO83F, PRO92F, SER140B, SER200B, SER216B, SER235B, SER74F, SER84F, SER88F, THR128F, THR131F, THR213B, THR230B, THR29B, THR63F, THR66F, THR71F, TRP135B, TRP67F, TYR137B, TYR234B, TYR38B, TYR81F, VAL214B, VAL231B, VAL233B, VAL34B, VAL37B, VAL65F, VAL78F, VAL87F, VAL89F
• C-E: ALA127E, ALA201C, ALA232C, ALA79E, ALA91E, ARG134C, ARG134E, ARG196C, ARG222C, ARG35C, ARG36C, ASN133E, ASN136C, ASN227C, ASN72E, ASN77E, ASN82E, ASP139C, ASP215C, ASP26C, ASP30C, GLN132C, GLN27C, GLN64E, GLN68E, GLN76E, GLU125E, GLU135E, GLY132E, GLY218C, GLY73E, GLY86E, HIS39C, ILE123E, ILE197C, ILE217C, ILE224C, ILE238C, ILE62E, ILE80E, LEU193C, LEU220C, LEU236C, LEU25C, LEU28C, LEU57E, LEU90E, LYS237C, LYS61E, LYS69E, LYS75E, MET219C, MET85E, PHE126E, PHE129E, PHE223C, PRO130E, PRO133C, PRO198C, PRO199C, PRO221C, PRO58E, PRO83E, PRO92E, SER140C, SER200C, SER216C, SER235C, SER59E, SER74E, SER84E, SER88E, THR128E, THR131E, THR213C, THR230C, THR29C, THR63E, THR66E, THR71E, TRP135C, TRP67E, TYR137C, TYR234C, TYR38C, TYR81E, VAL214C, VAL231C, VAL233C, VAL24C, VAL34C, VAL37C, VAL60E, VAL65E, VAL78E, VAL87E, VAL89E
• E-F: ALA54E, ALA54F, ARG101E, ARG101F, ARG110E, ARG110F, ARG234E, ARG234F, ASN229E, ASN229F, ASN36E, ASN36F, ASN55E, ASN55F, ASP106E, ASP106F, ASP233F, ASP37E, ASP37F, ASP46E, ASP46F, CYS51E, CYS51F, GLN34E, GLN34F, GLU197F, GLU98E, GLU98F, GLY107E, GLY107F, GLY41E, GLY41F, HIS231E, HIS231F, HIS50E, HIS50F, ILE109E, ILE109F, ILE227E, ILE227F, LEU100E, LEU100F, LEU138E, LEU138F, LEU49E, LEU49F, LYS178E, LYS178F, MET143E, MET143F, MET232E, MET232F, MET39E, MET39F, PHE104F, PHE126E, PHE126F, PHE42E, PHE42F, PHE53E, PHE53F, PHE99E, PRO179E, PRO179F, PRO180E, PRO180F, SER103E, SER103F, SER136F, SER181E, SER181F, SER184E, SER184F, SER38E, SER38F, SER52E, SER52F, THR105E, THR105F, THR108E, THR108F, THR141E, THR141F, THR45E, THR45F, TYR195F, TYR230E, TYR230F, TYR40E, TYR40F, VAL142E, VAL182E, VAL182F, VAL183E, VAL183F, VAL205E, VAL205F, VAL228E, VAL228F, VAL32E, VAL32F, VAL33E, VAL33F, VAL35E, VAL35F, VAL47E, VAL47F, VAL48E, VAL48F