3SJA

crystal structure of s. cerevisiae get3 in the open state in complex with get1 cytosolic domain

• Total interactions analyzed: 45
• Total true interactions: 19
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 45
  • Norm. En. per Res.: -5.0285
• Hub Node: B(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-25.0155	-30.3647	-204.007	-259.3872	115	5	3	9625	6	55	31
A-C	0.0	-4.3751	-59.1192	-63.4943	63	0	0	2909	0	19	22
A-D	-37.026	-45.1417	-144.117	-226.2847	45	4	4	5292	2	21	8
A-I	0.0	1.1941	-0.5433	0.6508	6	0	0	118	0	5	5
A-J	0.0	0.0	-0.1889	-0.1889	11	0	0	71	0	6	5
B-C	-33.7294	-47.0995	-143.271	-224.0999	45	3	4	5308	3	21	8
B-D	0.0	-10.5505	-55.1078	-65.6583	62	0	0	2752	0	19	22
B-E	0.0	2.4862	-6.5562	-4.07	8	1	0	253	0	5	5
B-F	-2.7253	-61.0051	-46.4871	-110.2174	41	11	0	2248	3	34	37
B-I	0.0	-45.5166	-41.5435	-87.0601	41	7	0	2342	1	36	40
B-J	0.0	0.0	-0.0011	-0.0011	2	0	0	3	0	0	0
D-E	0.0	0.0	-0.1304	-0.1304	6	0	0	49	0	5	3
D-F	0.0	0.0	-0.0453	-0.0453	2	0	0	15	0	0	0
E-F	-22.1754	-30.6828	-236.147	-289.0052	119	10	3	10640	6	55	32
E-G	0.0	-10.791	-53.8383	-64.6293	62	0	0	2704	0	19	22
E-H	-32.2684	-46.9948	-141.064	-220.3272	44	3	4	5229	3	21	8
F-G	-35.0012	-49.134	-134.792	-218.9272	45	3	4	5068	3	21	8
F-H	-4.7669	-7.3468	-56.0243	-68.1379	62	0	0	2747	0	19	23
I-J	0.0	-8.0421	-54.4506	-62.4927	62	0	0	2760	0	19	23

Interface residues

• A-B: ALA277A, ALA277B, ALA290A, ALA290B, ALA318A, ALA318B, ARG254A, ARG254B, ARG287A, ARG287B, ARG291A, ARG291B, ASN284A, ASN284B, ASP280A, ASP280B, ASP352A, ASP352B, CYS242A, CYS242B, CYS285A, CYS285B, CYS288A, CYS288B, CYS317A, CYS317B, GLN273A, GLN273B, GLN281A, GLN281B, GLN289A, GLN289B, GLN295A, GLN295B, GLU245A, GLU245B, GLU251A, GLU251B, GLU282A, GLU282B, GLU320A, GLU320B, GLU349A, GLU351A, GLU351B, GLU354A, GLU354B, GLY171A, GLY171B, GLY25A, GLY25B, GLY27A, GLY27B, GLY28A, GLY28B, GLY30A, GLY30B, GLY319A, GLY319B, GLY344A, HIS172A, HIS283A, HIS283B, ILE243A, ILE243B, ILE347A, ILE347B, LEU247A, LEU247B, LEU249A, LEU249B, LEU274A, LEU274B, LEU275A, LEU275B, LEU316A, LEU316B, LEU350A, LYS26A, LYS26B, LYS286A, LYS286B, LYS293B, LYS297A, LYS297B, LYS353A, MET294A, MET294B, PHE246A, PHE246B, PHE276A, PHE276B, PRO169A, PRO169B, PRO315A, PRO315B, SER244A, SER248A, SER248B, THR170A, THR170B, THR252A, THR252B, TRP292A, TRP292B, TYR250A, TYR250B, TYR298A, TYR298B, TYR338A, TYR338B, TYR348A, TYR348B, VAL29A, VAL29B
• A-C: ALA127A, ALA168A, ALA59A, ALA61C, ALA92A, ARG175A, ARG49C, ASN56C, ASN57C, ASN61A, ASN64C, ASN72C, ASN98A, ASP128A, ASP137A, ASP57A, ASP63C, ASP89A, ASP96A, ASP99A, GLN62C, GLN90C, GLU138A, GLU51C, GLU54C, GLY124A, GLY131A, GLY171A, GLY25A, GLY27A, GLY28A, GLY30A, HIS172A, HIS50C, HIS60A, ILE59C, LEU120A, LEU140A, LEU43C, LEU94A, LYS189A, LYS26A, LYS31A, LYS53C, LYS86C, LYS95A, MET35C, PHE55C, PRO169A, PRO58A, PRO90A, SER132A, SER141A, SER58C, SER60C, SER91A, THR170A, THR56A, TRP68C, TYR42C, TYR65C, VAL29A, VAL46C
• A-D: ALA61D, ALA66D, ARG254A, ARG73D, ASN64D, ASN71D, ASN72D, ASP300A, ASP303A, ASP308A, ASP63D, ASP76D, GLN257A, GLN301A, GLN62D, GLU245A, GLU251A, GLU253A, GLU304A, GLU307A, ILE256A, ILE260A, ILE269A, ILE302A, LEU247A, LEU249A, LEU305A, LYS297A, LYS67D, LYS70D, LYS74D, LYS80D, MET294A, PHE246A, PHE309A, SER248A, SER261A, SER60D, THR252A, THR69D, TRP68D, TYR250A, TYR298A, TYR306A, TYR65D
• A-I: ASN284A, ASP64I, CYS285A, HIS60I, LYS286A, LYS69I
• A-J: ASN284A, ASN64J, ASP352A, GLN281A, GLU282A, LYS345A, LYS67J, LYS70J, PHE55J, SER58J, TYR348A
• B-C: ALA61C, ALA66C, ARG254B, ARG73C, ASN64C, ASN71C, ASN72C, ASP300B, ASP303B, ASP308B, ASP63C, ASP76C, GLN257B, GLN301B, GLN62C, GLU245B, GLU251B, GLU253B, GLU304B, GLU307B, ILE256B, ILE260B, ILE269B, ILE302B, LEU247B, LEU249B, LEU305B, LYS297B, LYS67C, LYS70C, LYS74C, LYS80C, MET294B, PHE246B, PHE309B, SER248B, SER261B, SER60C, THR252B, THR69C, TRP68C, TYR250B, TYR298B, TYR306B, TYR65C
• B-D: ALA127B, ALA168B, ALA59B, ALA61D, ALA92B, ARG175B, ARG49D, ASN56D, ASN57D, ASN61B, ASN64D, ASN72D, ASN98B, ASP128B, ASP137B, ASP57B, ASP63D, ASP89B, ASP96B, ASP99B, GLN62D, GLN90D, GLU138B, GLU51D, GLU54D, GLY124B, GLY131B, GLY171B, GLY25B, GLY27B, GLY28B, GLY30B, HIS172B, HIS50D, HIS60B, ILE59D, LEU120B, LEU140B, LEU43D, LEU94B, LYS26B, LYS31B, LYS53D, LYS86D, LYS95B, MET35D, PHE55D, PRO169B, PRO58B, PRO90B, SER132B, SER141B, SER58D, SER60D, SER91B, THR170B, THR56B, TRP68D, TYR42D, TYR65D, VAL29B, VAL46D
• B-E: ARG75B, ASN284E, GLU68B, HIS283E, LYS286E, LYS69B, PHE70B, SER63B
• B-F: ALA74B, ALA92B, ARG151B, ARG75B, ASN279F, ASN284F, ASP280F, ASP352F, ASP73B, ASP89B, ASP96B, GLN152B, GLN281F, GLU156B, GLU282F, GLU349F, GLU351F, GLU354F, GLU68B, GLU87B, GLY155B, GLY344F, GLY67B, GLY71B, HIS283F, HIS60B, ILE341F, ILE347F, ILE88B, LEU350F, LYS345F, LYS353F, LYS69B, LYS72B, LYS76B, LYS95B, PHE70B, SER63B, THR78B, TYR348F, VAL346F
• B-I: ALA74I, ALA92I, ALA93I, ARG151I, ARG75I, ASP280B, ASP352B, ASP73I, ASP89I, ASP96I, GLN152I, GLN281B, GLU156I, GLU282B, GLU349B, GLU351B, GLU354B, GLU68I, GLU87I, GLY155I, GLY344B, GLY67I, GLY71I, HIS283B, HIS60I, ILE341B, ILE347B, ILE88I, LEU350B, LYS345B, LYS353B, LYS69I, LYS72I, LYS76I, LYS95I, PHE70I, SER63I, THR342B, THR78I, TYR348B, VAL346B
• B-J: LYS286B, PHE55J
• D-E: ASN64D, ASP352E, GLN281E, GLU282E, LYS67D, PHE55D
• D-F: LYS286F, PHE55D
• E-F: ALA277E, ALA277F, ALA290E, ALA290F, ALA318E, ALA318F, ARG254E, ARG254F, ARG287E, ARG287F, ARG291E, ARG291F, ASN279E, ASN279F, ASN284E, ASN284F, ASP280E, ASP280F, ASP352E, ASP352F, CYS242E, CYS242F, CYS285E, CYS285F, CYS288E, CYS288F, CYS317E, CYS317F, GLN273E, GLN273F, GLN289E, GLN289F, GLN295E, GLN295F, GLU245E, GLU245F, GLU251E, GLU251F, GLU278E, GLU278F, GLU282E, GLU282F, GLU320E, GLU320F, GLU349F, GLU351E, GLU351F, GLU354F, GLY171E, GLY171F, GLY25E, GLY25F, GLY27E, GLY27F, GLY28E, GLY28F, GLY30E, GLY30F, GLY319E, GLY319F, GLY344E, GLY344F, HIS172E, HIS172F, HIS283E, HIS283F, ILE243E, ILE243F, ILE347E, ILE347F, LEU247E, LEU247F, LEU249E, LEU249F, LEU274E, LEU274F, LEU275E, LEU275F, LEU316E, LEU316F, LEU350F, LYS26E, LYS26F, LYS286E, LYS286F, LYS293E, LYS297E, LYS297F, LYS353F, MET294E, MET294F, PHE246E, PHE246F, PHE276E, PHE276F, PRO169E, PRO169F, PRO315E, PRO315F, SER244E, SER244F, SER248E, SER248F, THR170E, THR170F, THR252E, THR252F, TRP292E, TRP292F, TYR250E, TYR250F, TYR298E, TYR298F, TYR338E, TYR338F, TYR348E, TYR348F, VAL29E, VAL29F
• E-G: ALA127E, ALA168E, ALA59E, ALA61G, ALA92E, ARG175E, ARG49G, ASN56G, ASN57G, ASN61E, ASN64G, ASN72G, ASN98E, ASP128E, ASP137E, ASP57E, ASP63G, ASP89E, ASP96E, ASP99E, GLN62G, GLN90G, GLU138E, GLU51G, GLU54G, GLY124E, GLY131E, GLY171E, GLY25E, GLY27E, GLY28E, GLY30E, HIS172E, HIS50G, HIS60E, ILE59G, LEU120E, LEU140E, LEU43G, LEU94E, LYS26E, LYS31E, LYS53G, LYS86G, LYS95E, MET35G, PHE55G, PRO169E, PRO58E, PRO90E, SER132E, SER141E, SER58G, SER60G, SER91E, THR170E, THR56E, TRP68G, TYR42G, TYR65G, VAL29E, VAL46G
• E-H: ALA61H, ALA66H, ARG254E, ARG73H, ASN64H, ASN71H, ASN72H, ASP300E, ASP303E, ASP308E, ASP63H, ASP76H, GLN257E, GLN301E, GLN62H, GLU245E, GLU251E, GLU253E, GLU304E, GLU307E, ILE256E, ILE260E, ILE269E, ILE302E, LEU247E, LEU249E, LEU305E, LYS297E, LYS67H, LYS70H, LYS80H, MET294E, PHE246E, PHE309E, SER248E, SER261E, SER60H, THR252E, THR69H, TRP68H, TYR250E, TYR298E, TYR306E, TYR65H
• F-G: ALA61G, ALA66G, ARG254F, ARG73G, ASN64G, ASN71G, ASN72G, ASP300F, ASP303F, ASP308F, ASP63G, ASP76G, GLN257F, GLN301F, GLN62G, GLU245F, GLU251F, GLU253F, GLU304F, GLU307F, ILE256F, ILE260F, ILE269F, ILE302F, LEU247F, LEU249F, LEU305F, LYS297F, LYS67G, LYS70G, LYS74G, LYS80G, MET294F, PHE246F, PHE309F, SER248F, SER261F, SER60G, THR252F, THR69G, TRP68G, TYR250F, TYR298F, TYR306F, TYR65G
• F-H: ALA127F, ALA168F, ALA59F, ALA61H, ALA92F, ARG175F, ARG49H, ASN56H, ASN57H, ASN61F, ASN64H, ASN72H, ASN98F, ASP128F, ASP137F, ASP57F, ASP63H, ASP89F, ASP96F, ASP99F, GLN62H, GLN90H, GLU138F, GLU51H, GLU54H, GLY124F, GLY131F, GLY171F, GLY25F, GLY27F, GLY28F, GLY30F, HIS172F, HIS50H, HIS60F, ILE59H, LEU120F, LEU140F, LEU43H, LEU94F, LYS26F, LYS31F, LYS53H, LYS86H, LYS95F, MET35H, PHE55H, PRO169F, PRO58F, PRO90F, SER132F, SER141F, SER58H, SER60H, SER91F, THR170F, THR56F, TRP68H, TYR42H, TYR65H, VAL29F, VAL46H
• I-J: ALA127I, ALA168I, ALA59I, ALA61J, ALA92I, ARG175I, ARG49J, ASN56J, ASN57J, ASN61I, ASN64J, ASN72J, ASN98I, ASP128I, ASP137I, ASP57I, ASP63J, ASP89I, ASP96I, ASP99I, GLN62J, GLN90J, GLU138I, GLU51J, GLU54J, GLY124I, GLY131I, GLY171I, GLY25I, GLY27I, GLY28I, GLY30I, HIS172I, HIS50J, HIS60I, ILE59J, LEU120I, LEU140I, LEU43J, LEU94I, LYS26I, LYS31I, LYS53J, LYS86J, LYS95I, MET35J, PHE55J, PRO169I, PRO58I, PRO90I, SER132I, SER141I, SER58J, SER60J, SER91I, THR170I, THR56I, TRP68J, TYR42J, TYR65J, VAL29I, VAL46J