3SGJ

unique carbohydrate-carbohydrate interactions are required for high affinity binding between fcgiii and antibodies lacking core fucose

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 57
  • Norm. En. per Res.: -3.6627
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-36.9693	-77.1685	372.838	258.7002	127	15	2	14057	7	22	25
A-C	-32.0855	-29.7832	-146.907	-208.7757	57	3	0	5427	1	23	10
B-C	-29.2796	-2.2312	-125.54	-157.0508	46	2	3	4444	0	10	4

Interface residues

• A-B: ALA231A, ALA231B, ARG355A, ARG355B, ASN361A, ASN361B, ASN389A, ASN389B, ASN390A, ASN390B, ASP356A, ASP356B, ASP399A, ASP399B, ASP401A, ASP401B, CYS226A, CYS229A, CYS229B, CYS367A, CYS367B, GLN347A, GLN347B, GLN362A, GLN362B, GLU233B, GLU345A, GLU345B, GLU357A, GLU357B, GLY371A, GLY371B, GLY402A, GLY402B, LEU234A, LEU234B, LEU235A, LEU235B, LEU351A, LEU351B, LEU358A, LEU358B, LEU365A, LEU365B, LEU368A, LEU368B, LEU398A, LEU398B, LEU406A, LEU406B, LEU410A, LEU410B, LEU441A, LEU441B, LYS360A, LYS360B, LYS370A, LYS370B, LYS392A, LYS392B, LYS409A, LYS409B, LYS439A, LYS439B, PHE404A, PHE404B, PHE405A, PHE405B, PRO227A, PRO227B, PRO228A, PRO228B, PRO230A, PRO230B, PRO232A, PRO232B, PRO346A, PRO352A, PRO352B, PRO353A, PRO353B, PRO395A, PRO395B, PRO396A, PRO396B, SER354A, SER354B, SER364A, SER364B, SER400A, SER400B, SER403A, SER403B, SER408A, SER408B, SER440A, SER440B, THR350A, THR350B, THR359A, THR359B, THR366A, THR366B, THR393A, THR393B, THR394A, THR394B, THR411A, THR411B, TRP381A, TRP381B, TYR349A, TYR349B, TYR391A, TYR391B, TYR407A, TYR407B, VAL348A, VAL348B, VAL363A, VAL363B, VAL369A, VAL369B, VAL397A, VAL397B, VAL412A, VAL412B
• A-C: ALA117C, ALA327A, ARG130C, ARG155C, ASN126C, ASN136C, ASN297A, ASN325A, ASP265A, ASP270A, GLN125C, GLN295A, GLU233A, GLU269A, GLU294A, GLY127C, GLY129C, GLY159C, GLY236A, GLY237A, HIS119C, HIS134C, HIS135C, HIS268A, ILE332A, LEU118C, LEU124C, LEU157C, LEU234A, LEU235A, LEU328A, LYS120C, LYS128C, LYS131C, LYS326A, PHE133C, PHE241A, PRO232A, PRO238A, PRO271A, PRO329A, SER160C, SER239A, SER267A, SER298A, THR122C, THR299A, TYR123C, TYR132C, TYR296A, TYR300A, VAL121C, VAL158C, VAL240A, VAL263A, VAL264A, VAL266A
• B-C: ALA117C, ALA231B, ALA327B, ALA330B, ASN115C, ASN325B, ASP265B, ASP270B, GLU21C, GLU233B, GLY159C, GLY236B, GLY237B, GLY89C, HIS119C, HIS87C, ILE332B, ILE88C, LEU118C, LEU157C, LEU20C, LEU234B, LEU235B, LEU328B, LEU91C, LYS114C, LYS161C, LYS22C, LYS326B, LYS334B, PHE241B, PRO232B, PRO238B, PRO329B, PRO331B, SER160C, SER239B, SER267B, THR116C, TRP113C, TRP90C, VAL158C, VAL163C, VAL240B, VAL263B, VAL264B