3SF4

crystal structure of the complex between the conserved cell polarity proteins inscuteable and lgn

• Total interactions analyzed: 15
• Total true interactions: 10
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 214
  • Norm. En. per Res.: -4.282
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-96.8404	44.9144	-213.449	-265.375	82	9	0	8093	8	23	40
A-C	-7.5789	-38.5249	-13.9651	-60.0689	19	0	0	813	2	10	12
A-D	-135.6629	-189.5353	-591.16	-916.3582	214	33	9	22882	14	53	43
A-E	0.0	0.0	-28.0154	-28.0154	23	2	0	1358	0	1	2
A-F	0.0	0.0	-0.5842	-0.5842	3	0	0	42	0	0	4
B-D	0.0	0.0	-0.2692	-0.2692	9	0	0	70	0	1	2
B-E	-117.616	-145.8668	-546.977	-810.4598	198	36	10	21475	10	40	32
C-D	0.0	0.0	-0.0082	-0.0082	4	0	0	4	0	0	4
C-F	-138.7535	-149.3039	-583.153	-871.2105	209	41	9	22863	12	50	45
D-E	0.0	0.0	1.2781	1.2781	15	5	0	392	0	0	0

Interface residues

• A-B: ALA214A, ALA214B, ALA217A, ALA217B, ALA254A, ALA254B, ARG168A, ARG168B, ARG212A, ARG212B, ASN210A, ASN210B, ASP169A, ASP169B, ASP213A, ASP213B, GLN172A, GLN172B, GLN220A, GLN220B, GLU162A, GLU162B, GLU165A, GLU165B, GLU219A, GLU219B, GLU250A, GLU250B, GLU252A, GLU252B, GLU256A, GLU256B, GLY161A, GLY161B, GLY209A, GLY209B, GLY249A, GLY249B, HIS205A, HIS205B, ILE216A, ILE216B, LEU171A, LEU171B, LEU207A, LEU207B, LEU208A, LEU208B, LEU241A, LEU241B, LEU248A, LEU248B, LEU288A, LEU288B, PHE163A, PHE163B, PHE211A, PHE211B, PHE247A, PHE247B, PHE251A, PHE251B, PRO164A, PRO164B, SER373A, THR204B, THR253A, THR253B, THR374B, TYR206A, TYR206B, TYR245A, TYR245B, TYR257A, TYR257B, VAL160B, VAL167A, VAL167B, VAL175A, VAL175B, VAL215A, VAL215B
• A-C: ALA35A, ALA35C, ARG26A, ARG26C, ASP32A, ASP32C, CYS28C, GLU19A, GLU23A, GLU23C, GLY31C, GLY36C, LEU22A, LEU27A, LEU27C, PHE39A, PHE39C, SER30A, SER30C
• A-D: ALA137A, ALA147A, ALA174A, ALA192A, ALA193A, ALA197A, ALA214A, ALA21A, ALA225A, ALA232A, ALA233A, ALA237A, ALA244A, ALA254A, ALA294A, ALA317A, ALA324A, ALA327A, ALA334A, ALA43A, ALA49D, ALA56A, ALA58D, ALA64A, ALA65D, ALA74A, ALA85A, ALA95A, ALA97A, ARG136A, ARG196A, ARG221A, ARG235A, ARG236A, ARG26A, ARG30D, ARG316A, ARG86A, ASN100A, ASN103A, ASN140A, ASN143A, ASN200A, ASN203A, ASN240A, ASN243A, ASN283A, ASN323A, ASN360A, ASN63A, ASP130A, ASP190A, ASP230A, ASP26D, ASP34D, ASP350A, ASP363A, ASP57D, ASP61D, ASP81A, ASP90A, CYS17A, CYS28A, CYS318A, CYS33A, CYS41D, CYS43D, CYS45D, GLN194A, GLN24D, GLN276A, GLN289A, GLN29D, GLN48D, GLN59D, GLN60A, GLN91A, GLU134A, GLU19A, GLU234A, GLU23A, GLU25A, GLU33D, GLU40D, GLU42D, GLU55D, GLU94A, GLY102A, GLY109A, GLY133A, GLY142A, GLY195A, GLY199A, GLY202A, GLY209A, GLY242A, GLY249A, GLY24A, GLY282A, GLY322A, GLY353A, GLY60D, GLY62A, GLY66D, GLY67D, GLY93A, GLY99A, HIS121A, HIS146A, HIS205A, HIS218A, HIS298A, HIS341A, HIS69A, HIS78A, HIS80A, ILE246A, ILE52D, ILE57A, ILE63D, ILE88A, LEU101A, LEU108A, LEU18A, LEU201A, LEU207A, LEU208A, LEU20A, LEU22A, LEU241A, LEU248A, LEU281A, LEU287A, LEU288A, LEU321A, LEU328A, LEU35D, LEU364A, LEU37D, LEU47D, LEU51A, LEU54A, LEU54D, LEU61A, LEU62D, LEU64D, LEU68A, LEU82A, LEU84A, LEU92A, LYS106A, LYS148A, LYS150A, LYS29A, LYS36D, LYS50D, LYS52A, LYS96A, MET32D, MET38D, MET44D, PHE163A, PHE198A, PHE211A, PHE247A, PHE251A, PHE40A, PHE66A, PRO51D, PRO68D, SER125A, SER239A, SER277A, SER27D, SER280A, SER320A, SER352A, SER53D, SER55A, SER59A, SER98A, THR104A, THR204A, THR261A, THR284A, THR286A, THR326A, THR356A, THR39D, THR53A, TRP319A, TRP31D, TYR139A, TYR145A, TYR178A, TYR206A, TYR238A, TYR245A, TYR258A, TYR279A, TYR285A, TYR291A, TYR325A, TYR58A, TYR65A, TYR67A, TYR71A, VAL107A, VAL132A, VAL144A, VAL25D, VAL273A, VAL28D, VAL46D
• A-E: ALA244A, ARG212A, ASN243A, GLN24E, GLN289A, GLN29E, GLU250A, GLY21E, GLY249A, ILE246A, LEU20E, LEU248A, LEU287A, LEU288A, LYS36E, MET23E, PHE211A, PHE247A, PHE251A, PRO19E, SER22E, THR286A, TYR245A
• A-F: ASP57F, GLU55F, MET13A
• B-D: ARG212B, GLN289B, GLN29D, GLU250B, GLY249B, LEU248B, LYS36D, PHE251B, VAL25D
• B-E: ALA137B, ALA147B, ALA174B, ALA192B, ALA193B, ALA197B, ALA21B, ALA225B, ALA232B, ALA233B, ALA237B, ALA244B, ALA254B, ALA294B, ALA317B, ALA324B, ALA327B, ALA357B, ALA43B, ALA49E, ALA56B, ALA64B, ALA65E, ALA74B, ALA85B, ALA95B, ALA97B, ARG136B, ARG196B, ARG221B, ARG235B, ARG236B, ARG26B, ARG30E, ARG316B, ARG86B, ASN100B, ASN103B, ASN140B, ASN143B, ASN200B, ASN203B, ASN240B, ASN243B, ASN283B, ASN323B, ASN360B, ASN63B, ASP130B, ASP230B, ASP26E, ASP34E, ASP350B, ASP81B, ASP90B, CYS318B, CYS41E, CYS43E, CYS45E, GLN194B, GLN24E, GLN276B, GLN289B, GLN29E, GLN48E, GLN60B, GLN91B, GLU134B, GLU19B, GLU23B, GLU25B, GLU33E, GLU40E, GLU42E, GLU94B, GLY102B, GLY133B, GLY142B, GLY153B, GLY195B, GLY199B, GLY202B, GLY209B, GLY21E, GLY242B, GLY249B, GLY24B, GLY282B, GLY322B, GLY353B, GLY62B, GLY66E, GLY67E, GLY93B, GLY99B, HIS121B, HIS146B, HIS218B, HIS298B, HIS341B, HIS69B, HIS78B, HIS80B, ILE246B, ILE52E, ILE57B, ILE63E, ILE88B, LEU101B, LEU171B, LEU201B, LEU207B, LEU208B, LEU20B, LEU20E, LEU22B, LEU241B, LEU248B, LEU281B, LEU287B, LEU288B, LEU321B, LEU359B, LEU35E, LEU37E, LEU47E, LEU51B, LEU54B, LEU61B, LEU62E, LEU64E, LEU82B, LEU84B, LEU92B, LYS106B, LYS148B, LYS150B, LYS29B, LYS36E, LYS50E, LYS52B, LYS96B, MET23E, MET32E, MET38E, MET44E, PHE163B, PHE198B, PHE211B, PHE247B, PHE251B, PHE40B, PHE66B, PRO19E, PRO51E, SER125B, SER239B, SER277B, SER27E, SER280B, SER320B, SER352B, SER53E, SER55B, SER59B, SER98B, THR104B, THR204B, THR261B, THR284B, THR286B, THR326B, THR356B, THR39E, THR53B, TRP319B, TRP31E, TYR139B, TYR145B, TYR178B, TYR206B, TYR238B, TYR258B, TYR279B, TYR285B, TYR291B, TYR58B, TYR65B, TYR67B, TYR71B, VAL107B, VAL132B, VAL144B, VAL167B, VAL25E, VAL273B, VAL28E, VAL46E
• C-D: ALA15C, ASP57D, GLU55D, PHE39C
• C-F: ALA137C, ALA147C, ALA174C, ALA192C, ALA193C, ALA197C, ALA214C, ALA21C, ALA225C, ALA232C, ALA233C, ALA237C, ALA244C, ALA254C, ALA294C, ALA317C, ALA324C, ALA327C, ALA357C, ALA43C, ALA49F, ALA56C, ALA58F, ALA64C, ALA65F, ALA74C, ALA85C, ALA95C, ALA97C, ARG136C, ARG196C, ARG221C, ARG235C, ARG236C, ARG26C, ARG30F, ARG316C, ARG86C, ASN100C, ASN103C, ASN140C, ASN143C, ASN200C, ASN203C, ASN240C, ASN243C, ASN283C, ASN323C, ASN360C, ASN63C, ASP130C, ASP190C, ASP230C, ASP26F, ASP34F, ASP350C, ASP57F, ASP61F, ASP81C, ASP90C, CYS17C, CYS28C, CYS318C, CYS33C, CYS41F, CYS43F, CYS45F, GLN194C, GLN24F, GLN276C, GLN289C, GLN29F, GLN48F, GLN59F, GLN60C, GLN91C, GLU134C, GLU19C, GLU23C, GLU25C, GLU33F, GLU40F, GLU42F, GLU55F, GLU56F, GLU94C, GLY102C, GLY109C, GLY133C, GLY142C, GLY195C, GLY199C, GLY202C, GLY209C, GLY242C, GLY249C, GLY24C, GLY282C, GLY322C, GLY60F, GLY62C, GLY66F, GLY67F, GLY93C, GLY99C, HIS121C, HIS146C, HIS218C, HIS298C, HIS341C, HIS69C, HIS78C, HIS80C, ILE246C, ILE312C, ILE52F, ILE57C, ILE63F, ILE88C, LEU101C, LEU108C, LEU18C, LEU201C, LEU207C, LEU20C, LEU22C, LEU241C, LEU248C, LEU281C, LEU287C, LEU288C, LEU321C, LEU35F, LEU37F, LEU47F, LEU51C, LEU54C, LEU54F, LEU61C, LEU62F, LEU64F, LEU68C, LEU82C, LEU84C, LEU92C, LYS106C, LYS148C, LYS150C, LYS29C, LYS36F, LYS50F, LYS52C, LYS96C, MET23F, MET32F, MET38F, MET44F, PHE163C, PHE198C, PHE211C, PHE247C, PHE251C, PHE40C, PHE66C, PRO51F, PRO68F, SER125C, SER239C, SER277C, SER27F, SER280C, SER320C, SER352C, SER53F, SER55C, SER59C, SER98C, THR104C, THR204C, THR261C, THR284C, THR286C, THR356C, THR39F, THR53C, TRP319C, TRP31F, TYR139C, TYR145C, TYR178C, TYR206C, TYR238C, TYR245C, TYR258C, TYR279C, TYR285C, TYR291C, TYR58C, TYR65C, TYR67C, TYR71C, VAL107C, VAL132C, VAL144C, VAL167C, VAL25F, VAL273C, VAL28F, VAL46F
• D-E: ASP26D, GLN24D, GLN24E, GLN29D, GLY21E, LEU20E, LEU35D, LYS36D, MET23E, MET32D, PRO19E, SER22E, TRP31D, VAL25D, VAL28D