3S3M

crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and dolutegravir (s/gsk1349572)

• Total interactions analyzed: 6
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 135
  • Norm. En. per Res.: -3.5455
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-76.8221	-19.8527	-381.964	-478.6388	135	13	4	16071	2	29	19

Interface residues

• A-B: ALA177A, ALA177B, ALA199B, ALA252A, ALA252B, ALA279A, ARG117B, ARG202A, ARG202B, ARG288A, ARG299A, ASN171A, ASN171B, ASN254A, ASN254B, ASN255A, ASN255B, ASN275A, ASN275B, ASN280A, ASP116B, ASP123A, ASP123B, ASP244B, ASP273A, ASP273B, ASP282A, ASP285A, GLN119A, GLN119B, GLN137B, GLN250A, GLN250B, GLN267A, GLN267B, GLN281A, GLN296A, GLU289A, GLU290A, GLU291A, GLY203A, GLY203B, GLY271A, GLY271B, HIS205B, HIS266A, HIS266B, ILE176A, ILE176B, ILE178A, ILE178B, ILE182B, ILE204A, ILE204B, ILE272A, ILE272B, LEU155A, LEU155B, LEU170A, LEU173A, LEU173B, LEU245B, LEU246A, LEU246B, LEU251A, LEU251B, LEU261B, LEU268A, LEU268B, LEU269A, LEU269B, LEU284A, LEU286A, LEU292A, LEU295A, LYS120A, LYS120B, LYS124A, LYS168A, LYS168B, LYS180A, LYS180B, LYS262B, MET149A, MET149B, PHE122A, PHE122B, PHE125B, PHE152A, PHE152B, PHE270A, PHE270B, PHE278B, PRO118B, PRO121A, PRO121B, PRO157B, PRO179A, PRO179B, PRO247A, PRO247B, PRO265B, PRO277A, PRO277B, SER175A, SER175B, SER274A, SER274B, SER293A, THR150A, THR150B, THR153A, THR153B, THR174A, THR174B, THR276A, THR276B, THR283A, THR287A, TRP154A, TRP154B, TRP198A, TYR156A, TYR156B, TYR243A, TYR243B, TYR263B, VAL172A, VAL172B, VAL181A, VAL181B, VAL248A, VAL248B, VAL249A, VAL249B