3RIS

crystal structure of the catalytic domain of uchl5, a proteasome- associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 82
  • Norm. En. per Res.: -3.6016
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-28.5795	55.1324	-218.597	-192.044	77	7	4	8448	0	32	28
A-D	0.0	0.0	-0.0121	-0.0121	2	0	0	2	0	1	1
B-C	0.0	0.0	-0.0687	-0.0687	5	0	0	8	0	1	1
B-D	-28.2376	62.5941	-227.54	-193.1835	77	9	4	8483	0	29	26
C-D	-75.7085	17.4052	-237.028	-295.3313	82	30	0	8296	0	27	25

Interface residues

• A-C: ALA144A, ALA144C, ARG137A, ARG137C, ARG145A, ARG145C, ARG28A, ARG28C, ASN141A, ASN141C, ASP134A, ASP134C, ASP152C, CYS27A, CYS27C, CYS9A, CYS9C, GLN138A, GLN138C, GLN146A, GLN146C, GLN147A, GLN147C, GLU109A, GLU109C, GLU113A, GLU113C, GLU116A, GLU116C, GLU150A, GLU150C, GLU20A, GLU20C, GLU7A, GLU7C, GLY108A, GLY108C, GLY24A, GLY24C, GLY26A, GLY26C, HIS140A, HIS140C, ILE136A, ILE136C, ILE22A, ILE22C, LEU111A, LEU111C, LEU21A, LEU21C, LYS23A, LYS23C, MET148A, MET148C, PHE114A, PHE114C, PHE117A, PHE117C, PHE143A, PHE143C, PHE149A, PHE149C, PHE25A, PHE25C, SER112A, SER112C, SER133A, SER133C, SER142A, SER142C, THR110A, THR110C, VAL135A, VAL135C, VAL139A, VAL139C
• A-D: GLN239A, GLU237D
• B-C: GLN239B, GLN239C, GLU237B, GLU237C, LEU238B
• B-D: ALA144B, ALA144D, ARG137B, ARG137D, ARG145B, ARG145D, ARG28B, ARG28D, ASN141B, ASN141D, ASP134B, ASP134D, CYS27B, CYS27D, CYS9B, CYS9D, GLN138B, GLN138D, GLN146B, GLN146D, GLN147B, GLN147D, GLU109B, GLU109D, GLU113B, GLU113D, GLU116B, GLU116D, GLU150B, GLU150D, GLU20B, GLU20D, GLU7B, GLU7D, GLY108B, GLY108D, GLY24B, GLY24D, GLY26B, GLY26D, HIS140B, HIS140D, ILE136B, ILE136D, ILE22B, ILE22D, LEU111B, LEU111D, LEU21B, LEU21D, LYS23B, LYS23D, MET148B, MET148D, PHE114B, PHE114D, PHE117B, PHE117D, PHE143B, PHE143D, PHE149B, PHE149D, PHE151D, PHE25B, PHE25D, SER112B, SER112D, SER133B, SER133D, SER142B, SER142D, THR110B, THR110D, VAL135B, VAL135D, VAL139B, VAL139D
• C-D: ALA190C, ALA190D, ARG174C, ARG174D, ARG73C, ARG73D, ASN172C, ASN172D, ASN192C, ASN192D, ASN99C, ASN99D, ASP187C, ASP187D, ASP194C, ASP194D, ASP195C, ASP195D, ASP71C, ASP71D, ASP75C, ASP75D, CYS100C, CYS100D, CYS191C, CYS191D, GLN103C, GLN103D, GLN119C, GLN119D, GLN193C, GLN193D, GLN70C, GLN70D, GLU116C, GLU116D, GLY173C, GLY173D, GLY189C, GLY189D, HIS102C, HIS102D, ILE77C, ILE77D, LEU107D, LEU175C, LEU175D, LEU74C, LEU74D, LEU98C, LEU98D, LYS115C, LYS115D, PHE78C, PHE78D, PRO170C, PRO170D, PRO185C, PRO185D, SER112C, SER112D, SER120C, SER120D, SER67C, SER67D, SER72C, SER72D, THR101C, THR101D, THR76C, THR76D, TRP196C, TRP196D, TYR176C, TYR176D, VAL169C, VAL169D, VAL171C, VAL171D, VAL68D, VAL69C, VAL69D