3RIG

sirt5 is an nad-dependent protein lysine demalonylase and desuccinylase

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 29
  • Norm. En. per Res.: -4.8073
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-27.4751	-5.8312	-106.736	-140.0423	68	4	2	4504	2	29	36
A-C	-41.476	-4.5279	-91.6833	-137.6872	33	3	2	2977	0	2	1
B-D	-47.3574	-5.4307	-86.6225	-139.4106	29	7	2	2972	0	2	1

Interface residues

• A-B: ALA116A, ALA116B, ALA120A, ALA120B, ALA122A, ALA122B, ALA149A, ALA149B, ALA300A, ALA300B, ALA302A, ALA302B, ALA48A, ALA48B, ARG119A, ARG119B, ARG127A, ARG127B, ARG133A, ARG133B, ARG44A, ARG44B, ASN115A, ASN115B, CYS124A, CYS124B, GLN131A, GLN131B, GLU113A, GLU113B, GLU123A, GLU123B, GLU299A, GLU299B, GLY117A, GLY117B, GLY150A, GLY150B, GLY294A, GLY294B, HIS118A, HIS118B, LEU128A, LEU128B, LEU297A, LEU297B, LEU301A, LEU301B, LYS130A, LYS130B, LYS148A, LYS148B, LYS152A, LYS152B, PHE47A, PHE47B, PRO114A, PRO114B, PRO292A, PRO292B, PRO298A, PRO298B, THR126A, THR126B, THR295A, THR295B, THR296A, THR296B
• A-C: ALA257A, ALA258A, ALA7C, ARG8C, ASN226A, ASP228A, ASP84A, GLN140A, GLN263A, GLN81A, GLN83A, GLU225A, GLY224A, GLY74A, HIS158A, LEU227A, LEU232A, MET259A, PHE223A, PHE260A, PRO229A, PRO256A, PRO88A, SER10C, SER252A, THR11C, THR6C, THR87A, TRP222A, TYR255A, VAL221A, VAL253A, VAL254A
• B-D: ALA257B, ALA258B, ALA7D, ARG8D, ASN226B, ASP228B, GLN81B, GLN83B, GLU225B, GLY224B, HIS158B, LEU227B, LEU232B, MET259B, PHE223B, PHE260B, PRO229B, PRO256B, PRO88B, SER10D, SER252B, THR11D, THR6D, THR87B, TRP222B, TYR255B, VAL221B, VAL253B, VAL254B