3RG1

crystal structure of the rp105/md-1 complex

• Total interactions analyzed: 120
• Total true interactions: 30
• Strongest Interaction:
  • Chains: E-H
  • Int. Res.: 64
  • Norm. En. per Res.: -3.3871
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	5.5558	-22.4491	-16.8933	55	0	1	1650	0	16	20
A-N	0.0	0.0	-5.6882	-5.6882	32	1	0	618	0	8	9
A-C	-60.5087	-32.6428	-215.411	-308.5625	102	13	3	9101	3	37	36
A-D	-35.9724	-22.5571	-126.225	-184.7545	64	6	2	4890	1	12	9
A-L	0.0	10.536	-38.5007	-27.9647	36	4	0	1531	0	15	10
E-B	0.0	0.0	-15.8421	-15.8421	42	2	0	912	0	15	25
E-F	0.0	6.431	-20.2395	-13.8085	50	0	1	1610	0	15	19
E-G	-65.8338	-34.869	-237.82	-338.5227	106	13	3	9635	4	36	35
E-H	-45.4428	-37.7426	-133.588	-216.7734	64	7	2	5102	2	12	9
I-F	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	4	2
I-J	0.0	5.2987	-19.762	-14.4633	50	0	1	1401	0	15	19
I-N	0.0	2.7328	-12.4588	-9.726	41	3	0	1077	0	12	22
I-K	-45.3316	-15.2243	-204.177	-264.7329	99	10	3	8738	2	36	35
I-L	-44.1673	-26.3787	-134.988	-205.534	63	7	2	5126	2	13	9
M-B	0.0	10.3011	-4.3129	5.9881	33	0	0	575	0	6	7
M-N	0.0	5.115	-22.4787	-17.3637	52	1	1	1643	0	17	20
M-H	0.0	9.6662	-48.3422	-38.676	39	5	0	1701	0	15	11
M-O	-56.6382	-34.5846	-208.48	-299.7028	104	11	3	8915	4	37	36
M-P	-49.2041	-27.2572	-130.33	-206.7913	63	11	2	5040	2	12	9
B-C	-36.1424	-25.8023	-132.1	-194.0447	62	8	2	4943	2	14	10
B-D	-54.6151	-31.9637	-207.03	-293.6088	97	11	3	8821	3	36	34
F-J	0.0	0.0	-0.0386	-0.0386	8	0	0	21	0	8	6
F-G	-32.9108	-24.2086	-118.714	-175.8334	61	6	2	4842	1	14	10
F-H	-46.2498	-30.7246	-200.846	-277.8204	100	6	3	8693	3	36	35
F-O	0.0	-24.9336	-17.9421	-42.8757	25	1	0	819	2	15	11
J-C	0.0	0.0	-1.7389	-1.7389	21	0	0	265	0	11	9
J-K	-18.2252	-23.1472	-105.666	-147.0384	58	3	2	4431	1	14	9
J-L	-46.9066	-32.0888	-201.092	-280.0874	100	6	3	8688	3	34	35
N-O	-30.1715	-25.0005	-125.008	-180.18	61	8	2	4929	2	14	10
N-P	-51.4751	-30.085	-197.41	-278.9701	101	3	3	8591	3	35	34

Interface residues

• A-B: ALA184A, ALA184B, ARG45A, ARG45B, ARG86A, ARG86B, ASN159A, ASN159B, ASN182A, ASN182B, ASN183A, ASN183B, ASN209A, ASN209B, ASN90A, ASN90B, ASP192A, ASP192B, ASP210A, ASP210B, GLN134A, GLN134B, GLN88A, GLN88B, GLY136A, GLY136B, HIS160A, HIS160B, HIS186A, HIS186B, ILE114A, ILE114B, ILE161A, ILE161B, ILE185A, ILE185B, ILE188A, ILE188B, LYS212A, LYS212B, PHE64A, PHE64B, PRO112A, PRO112B, SER138A, SER138B, SER158B, SER162A, SER162B, SER163A, SER163B, SER189A, SER189B, TYR187A, TYR187B
• A-N: ALA266A, ALA342N, ARG295A, ARG295N, ASP273A, ASP288N, CYS272A, CYS296A, GLU269A, GLU318N, GLY270A, GLY316A, GLY316N, ILE317N, LYS240A, LYS368N, PHE236A, PHE268A, SER265A, SER265N, SER290A, SER290N, SER291A, SER291N, SER292A, SER292N, SER315A, SER315N, SER343N, THR264A, THR293A, THR293N
• A-C: ALA120C, ALA307A, ALA330A, ARG111C, ARG112C, ARG285A, ARG72C, ARG86A, ASN111A, ASN124C, ASN159A, ASN182A, ASN183A, ASN205A, ASN207A, ASN280A, ASN329A, ASN38A, ASN41A, ASN62C, ASN63A, ASN64C, ASP102C, ASP179A, ASP257A, ASP259A, ASP304A, ASP376A, ASP74C, ASP83A, CYS109C, GLN116C, GLN134A, GLN181A, GLN282A, GLN46C, GLN88A, GLU100C, GLU115C, GLU256A, GLU40A, GLU59A, GLU73C, GLU76C, GLY110A, GLY110C, GLY114C, GLY121C, GLY157A, GLY208A, GLY230A, GLY231A, GLY253A, GLY354A, GLY43A, HIS155A, ILE117C, ILE123C, ILE65C, LEU103C, LEU42A, LEU45C, LEU71C, LYS105C, LYS113C, LYS228A, LYS283A, LYS325A, LYS353A, MET356A, MET69C, PHE106C, PHE108C, PHE131A, PHE255A, PHE60A, PHE62A, PHE81A, PRO104C, PRO122C, SER107C, SER153A, SER158A, SER61A, THR109A, THR133A, THR135A, THR254A, THR258A, THR306A, THR85A, TRP251A, TYR118C, TYR119C, TYR351A, TYR96C, VAL101C, VAL107A, VAL177A, VAL327A, VAL70C, VAL98C
• A-D: ALA117A, ALA120D, ALA29D, ARG111D, ARG31D, ARG66D, ASN139A, ASN90A, ASP47D, ASP53D, ASP95A, CYS30D, CYS55D, GLN116D, GLN46D, GLN69A, GLU118A, GLU141A, GLU168A, GLU94A, GLY121D, GLY136A, GLY49D, GLY68D, HIS146A, HIS27D, HIS93A, ILE114A, ILE117D, ILE137A, ILE143A, ILE65D, ILE68A, LEU113A, LEU140A, LEU38D, MET116A, MET69D, PHE115A, PHE142A, PHE48D, PHE50D, PHE67D, PRO112A, PRO144A, PRO167A, PRO25D, PRO66A, SER138A, SER51D, THR119A, THR135A, THR26D, THR28D, THR67A, TRP24D, TRP91A, TYR118D, TYR119D, TYR39D, VAL145A, VAL52D, VAL70D, VAL92A
• A-L: ALA160L, ARG285A, ARG357A, ARG57L, ASN311A, ASN340A, ASN34L, ASP134L, ASP288A, ASP334A, CYS337A, GLN335A, GLN338A, GLN58L, GLU129L, GLU132L, GLY133L, GLY312A, HIS309A, LEU289A, LEU310A, LEU313A, LYS358A, LYS87L, PHE333A, PRO131L, PRO314A, SER159L, SER287A, SER290A, SER315A, SER332A, SER86L, TYR135L, TYR158L, TYR262A
• E-B: ARG299E, ARG348B, ARG448B, ASN147E, ASN150E, ASN201B, ASN371B, ASN78E, ASP470B, GLN102B, GLN102E, GLN198E, GLN248B, GLN373B, GLN399B, GLN421B, GLN98E, GLU149E, GLU197E, GLU277B, GLU423B, GLU56E, GLY123E, HIS101E, HIS146E, HIS397B, HIS445B, ILE220E, ILE223E, ILE80E, LEU446B, LYS125E, LYS222E, LYS324B, LYS324E, PHE126B, PHE126E, PRO124E, PRO420B, SER221E, SER275E, THR200B
• E-F: ALA184E, ALA184F, ARG45E, ARG45F, ARG86E, ARG86F, ASN159E, ASN159F, ASN182E, ASN182F, ASN183E, ASN183F, ASN90E, ASN90F, ASP192E, ASP210E, ASP210F, GLN134E, GLN134F, GLN88E, GLN88F, GLY136E, GLY136F, HIS160E, HIS160F, HIS186E, HIS186F, ILE114E, ILE114F, ILE161E, ILE161F, ILE185E, ILE185F, ILE188F, LYS212E, LYS212F, PHE64E, PHE64F, PRO112E, PRO112F, SER138E, SER138F, SER162E, SER162F, SER163E, SER163F, SER189E, SER189F, TYR187E, TYR187F
• E-G: ALA120G, ALA307E, ALA330E, ARG111G, ARG112G, ARG285E, ARG72G, ARG86E, ASN111E, ASN124G, ASN125G, ASN159E, ASN182E, ASN183E, ASN205E, ASN207E, ASN280E, ASN329E, ASN38E, ASN41E, ASN62G, ASN63E, ASN64G, ASP102G, ASP179E, ASP257E, ASP259E, ASP304E, ASP376E, ASP43G, ASP74G, ASP83E, CYS109G, CYS99G, GLN116G, GLN134E, GLN181E, GLN282E, GLN46G, GLN88E, GLU100G, GLU115G, GLU256E, GLU40E, GLU59E, GLU73G, GLU76G, GLY110E, GLY110G, GLY114G, GLY121G, GLY157E, GLY208E, GLY230E, GLY231E, GLY253E, GLY354E, GLY43E, HIS155E, ILE117G, ILE123G, LEU103G, LEU108E, LEU42E, LEU45G, LEU71G, LYS105G, LYS113G, LYS228E, LYS283E, LYS353E, MET356E, MET69G, PHE106G, PHE108G, PHE131E, PHE255E, PHE60E, PHE62E, PHE81E, PRO104G, PRO122G, PRO44G, PRO97G, SER107G, SER153E, SER158E, SER61E, THR109E, THR133E, THR135E, THR254E, THR258E, THR306E, THR85E, TRP251E, TYR118G, TYR119G, TYR351E, TYR96G, VAL101G, VAL107E, VAL177E, VAL327E, VAL70G, VAL98G
• E-H: ALA117E, ALA120H, ALA29H, ARG111H, ARG31H, ARG66H, ASN139E, ASN90E, ASP47H, ASP53H, ASP95E, CYS30H, GLN116H, GLN46H, GLN69E, GLN98E, GLU118E, GLU141E, GLU168E, GLU94E, GLY121H, GLY136E, GLY49H, GLY68H, HIS146E, HIS27H, HIS93E, ILE114E, ILE117H, ILE137E, ILE143E, ILE65H, ILE68E, LEU113E, LEU140E, LEU38H, MET116E, MET69H, PHE115E, PHE142E, PHE48H, PHE50H, PHE67H, PRO112E, PRO144E, PRO167E, PRO25H, PRO66E, SER138E, SER51H, THR119E, THR135E, THR26H, THR28H, THR67E, TRP24H, TRP91E, TYR118H, TYR119H, TYR39H, VAL145E, VAL52H, VAL70H, VAL92E
• I-F: GLY316F, PHE236I
• I-J: ALA184I, ALA184J, ARG45I, ARG45J, ARG86I, ARG86J, ASN159I, ASN159J, ASN182I, ASN182J, ASN183I, ASN183J, ASN90I, ASN90J, ASP192J, ASP210I, ASP210J, GLN134I, GLN134J, GLN88I, GLN88J, GLY136I, GLY136J, HIS160I, HIS160J, HIS186I, HIS186J, ILE114I, ILE114J, ILE161I, ILE161J, ILE185I, ILE185J, LYS212I, LYS212J, PHE64I, PHE64J, PRO112I, PRO112J, PRO66J, SER138I, SER138J, SER158J, SER162I, SER162J, SER163I, SER163J, SER189J, TYR187I, TYR187J
• I-N: ARG299I, ARG348N, ARG448N, ASN147I, ASN150I, ASN201N, ASN244I, ASN78I, ASP470N, GLN102I, GLN173N, GLN198I, GLN248N, GLN373N, GLN399N, GLN421N, GLU149I, GLU197I, GLU277N, GLU423N, GLU56I, GLY123I, HIS101I, HIS146I, HIS397N, HIS445N, ILE220I, ILE80I, LEU446N, LYS125I, LYS125N, LYS128I, LYS222I, LYS324N, PHE126I, PHE126N, PRO124I, PRO420N, SER221I, SER275I, THR200N
• I-K: ALA120K, ALA307I, ALA330I, ARG111K, ARG112K, ARG72K, ARG86I, ASN111I, ASN124K, ASN159I, ASN182I, ASN183I, ASN205I, ASN207I, ASN280I, ASN329I, ASN38I, ASN41I, ASN62K, ASN63I, ASN64K, ASP102K, ASP179I, ASP257I, ASP259I, ASP304I, ASP376I, ASP43K, ASP74K, ASP83I, CYS109K, GLN116K, GLN134I, GLN181I, GLN282I, GLN46K, GLU100K, GLU115K, GLU256I, GLU40I, GLU59I, GLU73K, GLU76K, GLY110I, GLY110K, GLY114K, GLY121K, GLY157I, GLY208I, GLY230I, GLY231I, GLY253I, GLY354I, GLY43I, HIS155I, ILE117K, ILE123K, LEU103K, LEU42I, LEU45K, LEU71K, LYS105K, LYS113K, LYS228I, LYS283I, LYS353I, MET356I, MET69K, PHE106K, PHE108K, PHE131I, PHE255I, PHE60I, PHE62I, PHE81I, PRO104K, PRO122K, PRO44K, SER107K, SER153I, SER158I, SER61I, THR109I, THR133I, THR135I, THR254I, THR258I, THR306I, THR85I, TRP251I, TYR118K, TYR119K, TYR351I, TYR96K, VAL101K, VAL107I, VAL177I, VAL327I, VAL70K
• I-L: ALA117I, ALA120L, ALA29L, ARG31L, ARG66L, ASN139I, ASN169I, ASN90I, ASP47L, ASP53L, ASP95I, CYS30L, GLN116L, GLN46L, GLN69I, GLU118I, GLU141I, GLU168I, GLU94I, GLY121L, GLY136I, GLY49L, GLY68L, HIS146I, HIS27L, HIS93I, ILE114I, ILE117L, ILE137I, ILE143I, ILE65L, ILE68I, LEU113I, LEU140I, LEU38L, MET116I, MET69L, PHE115I, PHE142I, PHE48L, PHE50L, PHE67L, PRO112I, PRO144I, PRO167I, PRO25L, PRO66I, SER138I, SER51L, THR119I, THR135I, THR26L, THR28L, THR67I, TRP24L, TRP91I, TYR118L, TYR119L, TYR39L, VAL145I, VAL52L, VAL70L, VAL92I
• M-B: ALA266M, ALA342B, ARG295B, ARG295M, ASP273M, ASP288B, ASP288M, CYS272M, CYS296M, GLN243M, GLU269M, GLU318B, GLU318M, GLY270M, GLY316B, ILE317B, LYS240M, LYS368B, PHE236M, SER265B, SER265M, SER290B, SER290M, SER291B, SER291M, SER292B, SER292M, SER315B, SER315M, SER343B, THR264M, THR293B, THR293M
• M-N: ALA184M, ALA184N, ARG45M, ARG45N, ARG86M, ARG86N, ASN159M, ASN159N, ASN182M, ASN182N, ASN183M, ASN183N, ASN90M, ASN90N, ASP192N, ASP210M, ASP210N, GLN134M, GLN134N, GLN88M, GLN88N, GLY136M, GLY136N, HIS160M, HIS160N, HIS186M, HIS186N, ILE114M, ILE114N, ILE161M, ILE161N, ILE185M, ILE185N, ILE188N, LYS212M, LYS212N, PHE64M, PHE64N, PRO112M, PRO112N, SER138M, SER138N, SER158M, SER158N, SER162M, SER162N, SER163M, SER163N, SER189M, SER189N, TYR187M, TYR187N
• M-H: ALA160H, ALA308M, ARG285M, ARG357M, ARG57H, ASN311M, ASN340M, ASP134H, ASP288M, ASP334M, CYS337M, GLN335M, GLN338M, GLN58H, GLU129H, GLU132H, GLY133H, GLY312M, HIS309M, ILE130H, ILE339M, ILE91H, LEU289M, LEU310M, LEU313M, LYS358M, LYS87H, PHE286M, PHE333M, PRO131H, PRO314M, SER159H, SER287M, SER315M, SER332M, SER86H, TYR135H, TYR158H, TYR262M
• M-O: ALA120O, ALA307M, ALA330M, ARG111O, ARG112O, ARG285M, ARG72O, ARG86M, ASN111M, ASN124O, ASN125O, ASN159M, ASN182M, ASN183M, ASN205M, ASN207M, ASN280M, ASN329M, ASN38M, ASN41M, ASN62O, ASN63M, ASN64O, ASP102O, ASP179M, ASP257M, ASP259M, ASP260M, ASP304M, ASP376M, ASP74O, ASP83M, CYS109O, GLN116O, GLN134M, GLN181M, GLN282M, GLN46O, GLU100O, GLU115O, GLU256M, GLU40M, GLU59M, GLU73O, GLU76O, GLY110M, GLY110O, GLY114O, GLY121O, GLY157M, GLY208M, GLY230M, GLY231M, GLY253M, GLY354M, GLY43M, HIS155M, HIS379M, ILE117O, ILE123O, LEU103O, LEU42M, LEU45O, LEU71O, LYS105O, LYS113O, LYS228M, LYS283M, LYS325M, LYS353M, MET356M, MET69O, PHE106O, PHE108O, PHE131M, PHE255M, PHE60M, PHE62M, PHE81M, PRO104O, PRO122O, PRO97O, SER107O, SER153M, SER158M, SER61M, THR109M, THR133M, THR135M, THR254M, THR258M, THR306M, THR85M, TRP251M, TYR118O, TYR119O, TYR351M, TYR96O, VAL101O, VAL107M, VAL177M, VAL327M, VAL70O, VAL98O
• M-P: ALA117M, ALA120P, ALA29P, ARG111P, ARG31P, ARG66P, ASN139M, ASN90M, ASP47P, ASP53P, ASP95M, CYS30P, GLN116P, GLN46P, GLN69M, GLU118M, GLU141M, GLU168M, GLU94M, GLY121P, GLY136M, GLY49P, GLY68P, HIS146M, HIS27P, HIS93M, ILE114M, ILE117P, ILE137M, ILE143M, ILE65P, ILE68M, LEU113M, LEU140M, LEU38P, MET116M, MET69P, PHE115M, PHE142M, PHE48P, PHE50P, PHE67P, PRO112M, PRO144M, PRO167M, PRO25P, PRO66M, SER138M, SER51P, THR119M, THR135M, THR26P, THR28P, THR67M, TRP24P, TRP91M, TYR118P, TYR119P, TYR39P, VAL145M, VAL52P, VAL70P, VAL92M
• B-C: ALA117B, ALA120C, ALA29C, ARG111C, ARG31C, ARG66C, ASN139B, ASN90B, ASP47C, ASP53C, ASP95B, CYS30C, GLN116C, GLN46C, GLN69B, GLU118B, GLU141B, GLU168B, GLU94B, GLY121C, GLY136B, GLY49C, GLY68C, HIS27C, HIS93B, ILE114B, ILE117C, ILE137B, ILE143B, ILE65C, ILE68B, LEU113B, LEU140B, LEU38C, MET116B, MET69C, PHE115B, PHE142B, PHE48C, PHE50C, PHE67C, PRO112B, PRO144B, PRO167B, PRO25C, PRO66B, SER138B, SER51C, THR119B, THR135B, THR26C, THR28C, THR67B, TRP24C, TRP91B, TYR118C, TYR119C, TYR39C, VAL145B, VAL52C, VAL70C, VAL92B
• B-D: ALA120D, ALA307B, ALA330B, ARG111D, ARG112D, ARG72D, ARG86B, ASN111B, ASN124D, ASN125D, ASN159B, ASN182B, ASN205B, ASN207B, ASN280B, ASN329B, ASN38B, ASN41B, ASN62D, ASN63B, ASN64D, ASP102D, ASP179B, ASP257B, ASP304B, ASP376B, ASP74D, ASP83B, CYS109D, GLN116D, GLN134B, GLN181B, GLN282B, GLN46D, GLU100D, GLU115D, GLU256B, GLU40B, GLU59B, GLU73D, GLU76D, GLY110B, GLY110D, GLY114D, GLY121D, GLY157B, GLY208B, GLY230B, GLY231B, GLY253B, GLY354B, GLY43B, HIS155B, ILE117D, ILE123D, LEU103D, LEU42B, LEU45D, LEU71D, LYS105D, LYS113D, LYS228B, LYS283B, LYS31B, LYS353B, MET356B, MET69D, PHE106D, PHE108D, PHE131B, PHE255B, PHE60B, PHE62B, PHE81B, PRO104D, PRO122D, SER107D, SER153B, SER158B, SER61B, THR109B, THR133B, THR135B, THR254B, THR258B, THR306B, THR85B, TRP251B, TYR118D, TYR119D, TYR351B, TYR96D, VAL101D, VAL107B, VAL177B, VAL327B, VAL70D
• F-J: ALA266F, ALA266J, ASP273F, ASP273J, GLN243F, GLU269F, GLU269J, PHE236J
• F-G: ALA117F, ALA120G, ALA29G, ARG31G, ARG66G, ASN139F, ASN90F, ASP47G, ASP53G, ASP95F, CYS30G, GLN116G, GLN46G, GLN69F, GLU118F, GLU141F, GLU168F, GLU94F, GLY121G, GLY136F, GLY49G, GLY68G, HIS27G, HIS93F, ILE114F, ILE117G, ILE137F, ILE143F, ILE65G, ILE68F, LEU113F, LEU140F, LEU38G, MET116F, MET69G, PHE115F, PHE142F, PHE48G, PHE50G, PHE67G, PRO112F, PRO144F, PRO167F, PRO25G, PRO66F, SER138F, SER51G, THR119F, THR135F, THR26G, THR28G, THR67F, TRP24G, TRP91F, TYR118G, TYR119G, TYR39G, VAL145F, VAL52G, VAL70G, VAL92F
• F-H: ALA120H, ALA307F, ALA330F, ARG111H, ARG112H, ARG72H, ARG86F, ASN111F, ASN124H, ASN159F, ASN182F, ASN183F, ASN205F, ASN207F, ASN280F, ASN329F, ASN38F, ASN41F, ASN62H, ASN63F, ASN64H, ASP102H, ASP179F, ASP257F, ASP259F, ASP304F, ASP376F, ASP74H, ASP83F, CYS109H, GLN116H, GLN134F, GLN181F, GLN282F, GLN46H, GLU100H, GLU115H, GLU256F, GLU40F, GLU59F, GLU73H, GLU76H, GLY110F, GLY110H, GLY114H, GLY121H, GLY157F, GLY208F, GLY230F, GLY231F, GLY253F, GLY354F, GLY43F, HIS155F, HIS379F, ILE117H, ILE123H, LEU103H, LEU42F, LEU45H, LEU71H, LYS105H, LYS113H, LYS228F, LYS283F, LYS31F, LYS353F, MET356F, MET69H, PHE106H, PHE108H, PHE131F, PHE255F, PHE60F, PHE62F, PHE81F, PRO104H, PRO122H, PRO97H, SER107H, SER153F, SER158F, SER61F, THR109F, THR133F, THR135F, THR254F, THR258F, THR306F, THR85F, TRP251F, TYR118H, TYR119H, TYR351F, TYR96H, VAL101H, VAL107F, VAL177F, VAL327F, VAL70H
• F-O: ALA384F, ALA56O, ARG57O, ASN32O, ASN34O, ASP386F, CYS455F, GLN58O, GLU129O, GLU132O, GLU383F, GLU407F, GLY133O, GLY33O, GLY410F, HIS431F, HIS433F, ILE130O, LEU35O, LEU432F, LEU456F, PRO131O, PRO408F, SER385F, TYR158O
• J-C: ALA384J, ALA56C, ARG57C, ASN32C, ASN34C, CYS55C, GLN58C, GLU132C, GLU383J, GLU407J, GLY133C, GLY33C, HIS431J, HIS433J, LEU35C, LEU456J, LYS358J, PRO131C, PRO408J, SER385J, TYR158C
• J-K: ALA117J, ALA120K, ALA29K, ARG111K, ARG31K, ARG66K, ASN139J, ASN90J, ASP47K, ASP53K, ASP95J, CYS30K, GLN116K, GLN46K, GLN69J, GLU118J, GLU141J, GLU94J, GLY121K, GLY136J, GLY49K, GLY68K, HIS27K, HIS93J, ILE114J, ILE117K, ILE137J, ILE143J, ILE65K, LEU113J, LEU140J, LEU38K, MET116J, MET69K, PHE115J, PHE142J, PHE48K, PHE50K, PHE67K, PRO112J, PRO144J, PRO167J, PRO25K, SER138J, SER51K, THR119J, THR135J, THR26K, THR28K, THR67J, TRP24K, TRP91J, TYR118K, TYR119K, TYR39K, VAL145J, VAL52K, VAL70K
• J-L: ALA120L, ALA307J, ALA330J, ARG111L, ARG112L, ARG72L, ARG86J, ASN111J, ASN124L, ASN125L, ASN159J, ASN182J, ASN205J, ASN207J, ASN280J, ASN329J, ASN38J, ASN41J, ASN62L, ASN63J, ASN64L, ASP102L, ASP179J, ASP257J, ASP259J, ASP304J, ASP376J, ASP74L, ASP83J, CYS109L, CYS99L, GLN116L, GLN134J, GLN181J, GLN282J, GLN46L, GLU100L, GLU115L, GLU256J, GLU40J, GLU59J, GLU73L, GLU76L, GLY110J, GLY110L, GLY114L, GLY121L, GLY157J, GLY208J, GLY230J, GLY231J, GLY253J, GLY354J, GLY43J, HIS155J, HIS379J, ILE117L, ILE123L, ILE63L, LEU103L, LEU42J, LEU45L, LEU71L, LYS105L, LYS113L, LYS228J, LYS283J, LYS353J, MET356J, MET69L, PHE106L, PHE108L, PHE131J, PHE255J, PHE60J, PHE62J, PHE81J, PRO104L, PRO122L, PRO97L, SER107L, SER153J, SER158J, SER61J, THR109J, THR133J, THR254J, THR258J, THR306J, THR85J, TRP251J, TYR118L, TYR119L, TYR351J, TYR96L, VAL101L, VAL107J, VAL177J, VAL327J, VAL70L
• N-O: ALA117N, ALA120O, ALA29O, ARG31O, ARG66O, ASN139N, ASN90N, ASP47O, ASP53O, ASP95N, CYS30O, GLN116O, GLN46O, GLN69N, GLU118N, GLU141N, GLU168N, GLU94N, GLY121O, GLY136N, GLY49O, GLY68O, HIS27O, HIS93N, ILE114N, ILE117O, ILE137N, ILE143N, ILE65O, ILE68N, LEU113N, LEU140N, LEU38O, MET116N, MET69O, PHE115N, PHE142N, PHE48O, PHE50O, PHE67O, PRO112N, PRO144N, PRO167N, PRO25O, PRO66N, SER138N, SER51O, THR119N, THR135N, THR26O, THR28O, THR67N, TRP24O, TRP91N, TYR118O, TYR119O, TYR39O, VAL145N, VAL52O, VAL70O, VAL92N
• N-P: ALA120P, ALA307N, ALA330N, ARG111P, ARG112P, ARG72P, ARG86N, ASN111N, ASN124P, ASN125P, ASN159N, ASN182N, ASN183N, ASN205N, ASN207N, ASN280N, ASN329N, ASN38N, ASN41N, ASN62P, ASN63N, ASN64P, ASP102P, ASP179N, ASP257N, ASP259N, ASP260N, ASP304N, ASP376N, ASP74P, ASP83N, CYS109P, GLN116P, GLN134N, GLN181N, GLN282N, GLN46P, GLU100P, GLU115P, GLU256N, GLU40N, GLU59N, GLU73P, GLU76P, GLY110N, GLY110P, GLY114P, GLY121P, GLY157N, GLY208N, GLY230N, GLY231N, GLY253N, GLY354N, GLY43N, HIS155N, HIS379N, ILE117P, ILE123P, LEU103P, LEU42N, LEU45P, LEU71P, LYS105P, LYS113P, LYS228N, LYS283N, LYS325N, LYS353N, MET356N, MET69P, PHE106P, PHE108P, PHE131N, PHE255N, PHE60N, PHE62N, PHE81N, PRO104P, PRO122P, PRO97P, SER107P, SER153N, SER158N, SER61N, THR109N, THR133N, THR254N, THR258N, THR306N, THR85N, TRP251N, TYR118P, TYR119P, TYR351N, TYR96P, VAL101P, VAL107N, VAL177N, VAL327N, VAL70P