3R9A

human alanine-glyoxylate aminotransferase in complex with the tpr domain of human pex5p

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 328
  • Norm. En. per Res.: -4.2525
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-66.0391	-7.1126	-259.386	-332.5376	106	11	5	10838	0	16	15
A-C	-179.8854	-90.3105	-1124.63	-1394.8259	328	43	27	45058	5	61	55
A-D	0.0	0.0	-1.6169	-1.6169	8	0	0	212	0	2	3
C-D	-62.203	-21.6151	-272.816	-356.6342	118	13	4	11709	1	19	18

Interface residues

• A-B: ALA304A, ALA328A, ALA380B, ALA382A, ALA383A, ALA410B, ALA507B, ALA530B, ALA533B, ALA541B, ALA571B, ALA610B, ARG301A, ARG333A, ARG381A, ARG557B, ARG608B, ASN415B, ASN499B, ASN526B, ASN534B, ASN536B, ASN561B, ASN568B, ASN602B, ASP331A, ASP624B, CYS387A, CYS492B, CYS566B, GLN303A, GLN308A, GLN385A, GLN419B, GLN537B, GLN616B, GLU381B, GLU383B, GLU385B, GLU416B, GLU601B, GLY300A, GLY306A, GLY329A, GLY495B, GLY529B, GLY535B, GLY563B, GLY570B, GLY615B, HIS386A, HIS572B, ILE335A, ILE564B, ILE567B, ILE603B, LEU302A, LEU305A, LEU307A, LEU380A, LEU384A, LEU392A, LEU497B, LEU500B, LEU523B, LEU524B, LEU528B, LEU532B, LEU562B, LEU569B, LEU607B, LEU609B, LEU611B, LEU614B, LYS389A, LYS390A, LYS391A, LYS527B, MET613B, PHE413B, PHE498B, PHE511B, PHE579B, PRO327A, PRO388A, SER412B, SER417B, SER538B, SER558B, SER565B, SER605B, SER612B, SER617B, THR414B, THR531B, THR606B, TYR330A, TYR338A, TYR504B, TYR545B, TYR555B, TYR560B, TYR620B, VAL326A, VAL411B, VAL496B
• A-C: ALA13A, ALA13C, ALA213A, ALA213C, ALA277A, ALA277C, ALA280A, ALA280C, ALA39A, ALA39C, ALA40A, ALA40C, ALA85A, ALA85C, ALA88A, ALA88C, ARG111A, ARG111C, ARG118A, ARG118C, ARG197A, ARG197C, ARG233A, ARG233C, ARG273A, ARG273C, ARG292A, ARG333C, ARG360A, ARG360C, ARG36A, ARG36C, ARG71A, ARG71C, ASN212A, ASN212C, ASN22A, ASN22C, ASN286A, ASN286C, ASN32A, ASN32C, ASN367A, ASN367C, ASN72A, ASN72C, ASN92A, ASN92C, ASP114A, ASP114C, ASP196A, ASP196C, ASP243A, ASP243C, ASP341A, ASP341C, ASP52A, ASP52C, ASP58A, ASP58C, CYS366A, CYS366C, CYS84A, CYS84C, GLN110C, GLN198A, GLN198C, GLN208A, GLN208C, GLN23A, GLN23C, GLN282A, GLN282C, GLN44A, GLN44C, GLN55A, GLN55C, GLN65A, GLN65C, GLN69A, GLN69C, GLU117A, GLU117C, GLU274A, GLU274C, GLU281A, GLU281C, GLU285A, GLU285C, GLU346A, GLU346C, GLU59A, GLU59C, GLU62A, GLU62C, GLU87A, GLU87C, GLY116A, GLY116C, GLY120A, GLY120C, GLY206A, GLY206C, GLY216A, GLY216C, GLY27A, GLY27C, GLY283A, GLY283C, GLY29A, GLY29C, GLY352A, GLY352C, GLY41A, GLY41C, GLY42A, GLY42C, GLY47A, GLY47C, GLY63A, GLY63C, GLY80A, GLY80C, GLY82A, GLY82C, HIS261A, HIS261C, HIS262A, HIS262C, HIS4C, HIS83A, HIS83C, ILE107A, ILE107C, ILE115A, ILE115C, ILE119A, ILE119C, ILE20A, ILE20C, ILE244A, ILE244C, ILE264A, ILE264C, ILE267A, ILE267C, ILE279A, ILE279C, ILE340A, ILE340C, ILE37A, ILE37C, ILE46A, ILE46C, ILE56A, ILE56C, ILE60A, ILE60C, ILE64A, ILE64C, ILE78A, ILE78C, LEU14A, LEU14C, LEU15A, LEU15C, LEU18A, LEU18C, LEU193A, LEU193C, LEU242A, LEU242C, LEU247C, LEU24A, LEU24C, LEU25A, LEU25C, LEU269A, LEU269C, LEU272A, LEU272C, LEU276A, LEU276C, LEU278A, LEU278C, LEU284A, LEU284C, LEU33A, LEU33C, LEU351A, LEU351C, LEU43A, LEU43C, LEU6A, LEU6C, LEU7A, LEU7C, LEU86A, LEU86C, LEU90A, LEU90C, LYS12A, LYS12C, LYS16A, LYS16C, LYS236A, LYS236C, LYS245A, LYS245C, LYS51A, LYS51C, LYS5C, LYS61A, LYS61C, MET195A, MET195C, MET259A, MET259C, MET348A, MET348C, MET38A, MET38C, MET45A, MET45C, MET49A, MET49C, MET53A, MET53C, MET57A, PHE238A, PHE238C, PHE240A, PHE240C, PHE68A, PHE68C, PRO10A, PRO10C, PRO11A, PRO11C, PRO17A, PRO17C, PRO192A, PRO192C, PRO214A, PRO214C, PRO215A, PRO215C, PRO21A, PRO21C, PRO237A, PRO237C, PRO257A, PRO265A, PRO265C, PRO28C, PRO30A, PRO30C, PRO34A, PRO34C, PRO35A, PRO35C, PRO96A, PRO96C, SER159C, SER19A, SER19C, SER207A, SER207C, SER218A, SER239A, SER239C, SER268A, SER268C, SER271A, SER271C, SER275A, SER275C, SER31A, SER31C, SER48A, SER48C, SER50A, SER50C, SER79A, SER79C, SER81A, SER81C, THR217A, THR217C, THR235A, THR235C, THR263A, THR263C, THR355C, THR70A, THR70C, THR9A, THR9C, TRP108A, TRP108C, TRP246A, TRP246C, TRP288A, TRP288C, TYR194A, TYR194C, TYR241A, TYR241C, TYR260A, TYR260C, TYR270A, TYR270C, TYR54A, TYR54C, TYR66A, TYR66C, VAL113A, VAL113C, VAL185A, VAL185C, VAL266A, VAL266C, VAL67A, VAL67C, VAL8A, VAL8C, VAL91A, VAL91C
• A-D: ASP255A, ASP465D, GLN256A, LEU462D, LEU463D, PRO257A, SER464D, SER466D
• C-D: ALA304C, ALA325C, ALA328C, ALA380D, ALA382C, ALA383C, ALA410D, ALA422D, ALA507D, ALA530D, ALA533D, ALA541D, ALA571D, ALA610D, ARG333C, ARG381C, ARG420D, ARG557D, ARG608D, ARG626D, ASN415D, ASN499D, ASN526D, ASN534D, ASN536D, ASN561D, ASN568D, ASN602D, ASP331C, ASP334C, ASP624D, CYS387C, CYS492D, CYS566D, GLN303C, GLN308C, GLN384D, GLN385C, GLN419D, GLN421D, GLN537D, GLU381D, GLU383D, GLU385D, GLU416D, GLU601D, GLY306C, GLY329C, GLY356C, GLY495D, GLY529D, GLY535D, GLY563D, GLY570D, GLY615D, HIS386C, HIS572D, ILE335C, ILE564D, ILE567D, ILE603D, LEU302C, LEU305C, LEU307C, LEU380C, LEU384C, LEU386D, LEU392C, LEU418D, LEU426D, LEU462D, LEU463D, LEU497D, LEU500D, LEU523D, LEU524D, LEU528D, LEU532D, LEU562D, LEU569D, LEU607D, LEU609D, LEU611D, LEU614D, LYS389C, LYS390C, LYS391C, LYS527D, MET613D, PHE413D, PHE498D, PHE511D, PHE579D, PRO327C, PRO388C, SER412D, SER417D, SER461D, SER538D, SER558D, SER565D, SER605D, SER612D, SER617D, THR355C, THR414D, THR531D, THR606D, TRP332C, TYR330C, TYR504D, TYR545D, TYR555D, TYR560D, TYR620D, VAL326C, VAL411D, VAL496D