3R8W

structure of 3-isopropylmalate dehydrogenase isoform 2 from arabidopsis thaliana at 2.2 angstrom resolution

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 196
  • Norm. En. per Res.: -4.9012
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-239.0064	-46.0303	-669.094	-954.1307	195	44	26	27200	14	72	66
A-D	-22.098	-2.2979	-117.426	-141.8219	52	4	0	4442	0	32	33
C-D	-250.6895	-31.8575	-678.081	-960.628	196	43	26	27239	14	71	65

Interface residues

• A-B: ALA119A, ALA119B, ALA127A, ALA127B, ALA167A, ALA167B, ALA168A, ALA168B, ALA195A, ALA195B, ALA200A, ALA200B, ALA228A, ALA228B, ALA229A, ALA229B, ALA256A, ALA256B, ARG108A, ARG108B, ARG124A, ARG124B, ARG136A, ARG136B, ARG148A, ARG148B, ARG205A, ARG205B, ARG207A, ARG207B, ARG234A, ARG234B, ARG89A, ARG89B, ASN153A, ASN153B, ASN155B, ASN162A, ASN162B, ASN196A, ASN196B, ASN227A, ASN227B, ASN245A, ASN245B, ASN246A, ASN246B, ASP118A, ASP118B, ASP172A, ASP172B, ASP226A, ASP226B, ASP235A, ASP235B, ASP250A, ASP250B, ASP254A, ASP254B, GLN231A, GLN231B, GLN238A, GLN238B, GLU125A, GLU125B, GLU146A, GLU146B, GLU157A, GLU157B, GLU158A, GLU158B, GLU164A, GLU164B, GLU170A, GLU170B, GLU199A, GLU199B, GLU255A, GLU255B, GLU91A, GLU91B, GLY141A, GLY141B, GLY145A, GLY145B, GLY149A, GLY149B, GLY156A, GLY156B, GLY160A, GLY160B, GLY249A, GLY249B, GLY261A, GLY261B, HIS169A, HIS169B, HIS283A, HIS283B, ILE142A, ILE142B, ILE150A, ILE150B, ILE171A, ILE171B, ILE202A, ILE202B, ILE247A, ILE247B, ILE251A, ILE251B, ILE259A, ILE259B, ILE263A, ILE263B, ILE282A, ILE282B, LEU116A, LEU116B, LEU122A, LEU122B, LEU198A, LEU198B, LEU203A, LEU203B, LEU232A, LEU232B, LEU252A, LEU252B, LEU266A, LEU266B, LEU95A, LEU95B, LYS123A, LYS123B, LYS151A, LYS151B, LYS194A, LYS194B, LYS206A, LYS206B, LYS86A, LYS86B, MET230A, MET230B, MET258A, MET258B, PHE144A, PHE144B, PHE161A, PHE161B, PHE248A, PHE248B, PRO147A, PRO147B, PRO236A, PRO236B, SER120A, SER120B, SER201A, SER201B, SER253A, SER253B, SER257A, SER257B, THR121A, THR121B, THR152A, THR152B, THR163A, THR163B, THR260A, THR260B, TRP204A, TRP204B, TYR143A, TYR143B, TYR166A, TYR166B, TYR224A, TYR224B, VAL117A, VAL117B, VAL126A, VAL126B, VAL159A, VAL159B, VAL165A, VAL165B, VAL197A, VAL197B, VAL225A, VAL225B, VAL233A, VAL233B
• A-D: ALA182D, ALA48A, ALA49A, ALA64A, ALA65A, ARG183D, ARG185D, ARG186D, ARG41A, ASP217D, ASP240D, ASP51A, GLN96A, GLU180D, GLU214D, GLU219D, GLU315D, GLU42A, GLU59A, GLU60A, GLU67A, GLY187D, GLY54A, HIS87A, ILE62A, LEU189D, LEU220D, LEU52A, LEU57A, LYS184D, LYS188D, LYS309D, LYS316D, LYS319D, LYS3D, LYS66A, LYS92A, MET43A, PHE179D, PHE40A, PRO216D, PRO44A, PRO58A, SER213D, SER63A, THR181D, THR61A, THR6A, TYR215D, VAL218D, VAL53A, VAL55A
• C-D: ALA119C, ALA119D, ALA127C, ALA127D, ALA167C, ALA167D, ALA168C, ALA168D, ALA195C, ALA195D, ALA200C, ALA200D, ALA228C, ALA228D, ALA229C, ALA229D, ALA256C, ALA256D, ARG108C, ARG108D, ARG124C, ARG124D, ARG136C, ARG136D, ARG148C, ARG148D, ARG205C, ARG205D, ARG207C, ARG207D, ARG234C, ARG234D, ARG89C, ARG89D, ASN153C, ASN153D, ASN155C, ASN162C, ASN162D, ASN196C, ASN196D, ASN227C, ASN227D, ASN245C, ASN245D, ASN246C, ASN246D, ASP118C, ASP118D, ASP172C, ASP172D, ASP193C, ASP226C, ASP226D, ASP235C, ASP235D, ASP250C, ASP250D, ASP254C, ASP254D, GLN231C, GLN231D, GLN238C, GLN238D, GLU125C, GLU125D, GLU146C, GLU146D, GLU157C, GLU157D, GLU158C, GLU158D, GLU164C, GLU164D, GLU170C, GLU170D, GLU199C, GLU199D, GLU255C, GLU255D, GLU91C, GLU91D, GLY141C, GLY141D, GLY145C, GLY145D, GLY149C, GLY149D, GLY156C, GLY156D, GLY160C, GLY160D, GLY249C, GLY249D, GLY261C, GLY261D, HIS169C, HIS169D, HIS283C, HIS283D, ILE142C, ILE142D, ILE150C, ILE150D, ILE171C, ILE171D, ILE202C, ILE202D, ILE247C, ILE247D, ILE251C, ILE251D, ILE259C, ILE259D, ILE263C, ILE263D, ILE282C, ILE282D, LEU116C, LEU116D, LEU122C, LEU122D, LEU198C, LEU198D, LEU203C, LEU203D, LEU232C, LEU232D, LEU252C, LEU252D, LEU266C, LEU266D, LEU95C, LEU95D, LYS123C, LYS123D, LYS151C, LYS151D, LYS194C, LYS194D, LYS206C, LYS206D, LYS86C, LYS86D, MET230C, MET230D, MET258C, MET258D, PHE144C, PHE144D, PHE161C, PHE161D, PHE248C, PHE248D, PRO147C, PRO147D, PRO236C, PRO236D, SER120C, SER120D, SER201C, SER201D, SER253C, SER253D, SER257C, SER257D, THR121C, THR121D, THR152C, THR152D, THR163C, THR163D, THR260C, THR260D, TRP204C, TRP204D, TYR143C, TYR143D, TYR166C, TYR166D, TYR224C, TYR224D, VAL117C, VAL117D, VAL126C, VAL126D, VAL159C, VAL159D, VAL165C, VAL165D, VAL197C, VAL197D, VAL225C, VAL225D, VAL233C, VAL233D