3QYM

structure of p63 dna binding domain in complex with a 10 base pair a/t rich response element half site

• Total interactions analyzed: 120
• Total true interactions: 11
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 34
  • Norm. En. per Res.: -2.6251
• Hub Node: C(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-11.6206	0.0	-25.537	-37.1576	30	7	1	1795	0	1	2
A-D	0.0	20.0714	-30.1573	-10.0859	65	12	0	2974	0	12	9
B-D	0.0	0.0	-0.1722	-0.1722	6	0	0	61	0	1	0
C-D	-28.5384	0.0	-60.716	-89.2544	34	15	1	2291	0	1	4
C-E	-10.7467	5.1895	-53.2932	-58.8504	57	28	2	4165	0	6	6
C-F	0.0	5.3407	0.0	5.3407	2	0	0	0	0	2	4
D-F	-4.1499	3.4785	-60.4746	-61.1459	55	14	1	3872	0	6	6
E-F	-18.4158	0.0	-49.4226	-67.8384	29	5	1	1999	0	1	4
E-G	0.0	0.0	-0.0064	-0.0064	3	0	0	9	0	0	0
E-H	0.0	16.6459	-23.4058	-6.7599	51	7	0	2308	0	11	9
G-H	-16.9281	0.0	-39.6099	-56.538	32	14	1	2100	0	1	3

Interface residues

• A-B: ASN207A, ASN207B, ASN270A, ASN270B, ASN278A, ASN278B, CYS205A, CYS205B, CYS273A, CYS273B, GLU209A, GLU209B, GLU213A, GLU213B, GLY275A, GLY275B, GLY276A, GLY276B, HIS208A, HIS208B, LEU210A, LEU210B, MET277B, PRO206A, PRO206B, SER211A, SER211B, SER272A, VAL274A, VAL274B
• A-D: ALA167A, ALA167D, ALA220A, ALA220D, ALA234A, ALA234D, ARG212A, ARG212D, ARG227D, ASN215A, ASN215D, ASN231A, ASN231D, ASN266A, ASN266D, CYS170A, CYS170D, GLN143A, GLN165A, GLN165D, GLN173A, GLN218A, GLN218D, GLN255A, GLN255D, GLU213A, GLU213D, GLU216A, GLU216D, GLU229A, GLU229D, GLU252A, GLY217A, GLY217D, GLY230A, GLY230D, HIS233A, HIS233D, ILE172A, ILE219A, ILE219D, LEU264A, LEU264D, LYS168A, LYS168D, PHE214A, PHE214D, PRO171A, PRO171D, PRO222D, SER232A, SER232D, THR152A, THR152D, THR169A, THR169D, THR258A, THR261A, THR262A, THR262D, TYR265A, VAL228A, VAL228D, VAL263A, VAL263D
• B-D: ALA148D, GLN144D, GLU196B, HIS197B, SER146D, THR147D
• C-D: ARG204C, ARG204D, ARG212C, ASN207C, ASN207D, ASN270C, ASN270D, ASN278C, ASN278D, CYS205C, CYS205D, CYS269C, CYS273C, CYS273D, GLU209C, GLU209D, GLU213C, GLY275C, GLY275D, GLY276C, GLY276D, HIS208C, HIS208D, LEU210C, LEU210D, MET277D, PRO206C, PRO206D, SER211C, SER211D, SER272C, SER272D, VAL274C, VAL274D
• C-E: ALA125E, ALA148C, ALA151C, ALA167C, ALA195E, ARG298E, ASN129E, ASN231C, ASN266C, ASP131E, CYS170C, GLN143C, GLN165C, GLN255C, GLN294E, GLU196E, GLU200E, GLU229C, GLU252C, GLU259C, GLY134E, GLY230C, GLY257C, GLY297E, HIS197E, HIS233C, ILE172C, ILE241E, ILE285E, LEU264C, LEU296E, LYS168C, LYS194E, PHE260C, PRO127E, PRO133E, PRO171C, PRO254C, SER126E, SER128E, SER150C, SER232C, THR130E, THR152C, THR169C, THR199E, THR258C, THR261C, THR262C, TRP153C, TYR132E, TYR265C, VAL198E, VAL228C, VAL256C, VAL263C, VAL295E
• C-F: GLU216C, GLU216F
• D-F: ALA125D, ALA148F, ALA151F, ALA167F, ALA195D, ARG298D, ASN129D, ASN231F, ASN266F, ASP131D, CYS170F, GLN143F, GLN165F, GLN255F, GLN294D, GLU196D, GLU200D, GLU229F, GLU252F, GLU259F, GLY134D, GLY230F, GLY257F, GLY297D, HIS197D, HIS233F, ILE241D, ILE285D, LEU264F, LEU296D, LYS168F, LYS194D, PHE260F, PRO127D, PRO133D, PRO171F, PRO254F, SER126D, SER128D, SER150F, SER232F, THR130D, THR152F, THR169F, THR199D, THR258F, THR261F, THR262F, TRP153F, TYR132D, TYR265F, VAL198D, VAL256F, VAL263F, VAL295D
• E-F: ARG204E, ASN207E, ASN207F, ASN270F, ASN278E, ASN278F, CYS205E, CYS205F, CYS273E, CYS273F, GLU209E, GLU209F, GLU213F, GLY275E, GLY275F, GLY276E, GLY276F, HIS208E, HIS208F, LEU210E, LEU210F, MET277E, PRO206E, PRO206F, SER211E, SER211F, SER272F, VAL274E, VAL274F
• E-G: GLU196G, SER146E, THR147E
• E-H: ALA167E, ARG212E, ARG227E, ASN215E, ASN231E, ASN231H, ASN266E, CYS170H, GLN143H, GLN165E, GLN173H, GLN218E, GLN218H, GLN255E, GLN255H, GLU213E, GLU216E, GLU216H, GLU229E, GLU229H, GLU252H, GLY217E, GLY217H, GLY230E, GLY230H, HIS233E, HIS233H, ILE172H, ILE219E, ILE219H, LEU264E, LEU264H, LYS168E, LYS168H, PHE214E, PHE214H, PRO171E, PRO171H, PRO222E, SER232E, SER232H, THR152E, THR152H, THR169E, THR169H, THR258H, THR261H, THR262E, THR262H, TYR265H, VAL263H
• G-H: ARG204G, ARG204H, ASN207G, ASN207H, ASN270G, ASN270H, ASN278G, ASN278H, CYS205G, CYS205H, CYS273G, CYS273H, GLU209G, GLU209H, GLU213G, GLU213H, GLY275G, GLY275H, GLY276G, GLY276H, HIS208G, HIS208H, LEU210G, LEU210H, MET277G, PRO206G, PRO206H, SER211G, SER211H, SER272H, VAL274G, VAL274H