3QX3

human topoisomerase iibeta in complex with dna and etoposide

• Total interactions analyzed: 15
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 195
  • Norm. En. per Res.: -3.7348
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-139.0496	-137.7926	-451.443	-728.2852	195	19	7	18720	7	70	65

Interface residues

• A-B: ALA637B, ALA761A, ALA761B, ALA764A, ALA764B, ALA768A, ALA768B, ALA817A, ALA817B, ARG1084A, ARG1084B, ARG494A, ARG494B, ARG752A, ARG752B, ARG756A, ARG756B, ARG820A, ARG820B, ASN1083A, ASN1083B, ASN1139A, ASN1139B, ASN1143A, ASN1143B, ASP1088A, ASP1088B, ASP1137A, ASP1137B, ASP1201A, ASP1201B, ASP815A, ASP815B, ASP979A, ASP979B, GLN1067A, GLN1067B, GLN1076A, GLN1076B, GLN762A, GLN762B, GLN778A, GLN778B, GLN805A, GLN805B, GLN850A, GLN850B, GLN949A, GLN949B, GLU1073A, GLU1073B, GLU1082A, GLU1082B, GLU1152A, GLU1152B, GLU1155A, GLU1155B, GLU1198A, GLU1200A, GLU757A, GLU757B, GLU769A, GLU769B, GLU777A, GLU777B, GLU975A, GLU975B, GLY1077A, GLY1077B, GLY765A, GLY765B, GLY776A, GLY776B, HIS775A, HIS775B, HIS811A, HIS811B, HIS977A, HIS977B, ILE1071A, ILE1071B, ILE1075A, ILE1075B, ILE1079A, ILE1079B, ILE1081A, ILE1081B, ILE1090A, ILE1090B, ILE1141A, ILE1141B, ILE492A, LEU1072A, LEU1072B, LEU1089A, LEU1089B, LEU1093A, LEU1093B, LEU1142A, LEU1142B, LEU1146A, LEU1146B, LEU1149A, LEU1149B, LEU484A, LEU763A, LEU763B, LEU780B, LEU810A, LEU810B, LYS1074A, LYS1074B, LYS1086A, LYS1086B, LYS1087A, LYS1087B, LYS1151A, LYS1151B, LYS1153A, LYS1153B, LYS638A, LYS638B, LYS641A, LYS641B, LYS751B, LYS759A, LYS759B, LYS952A, LYS952B, LYS974A, LYS974B, MET1144A, MET1144B, MET770A, MET770B, MET781A, MET781B, PHE1070A, PHE1070B, PHE1138A, PHE1138B, PHE823A, PHE823B, PRO1136A, PRO819A, SER1085A, SER1085B, SER1145A, SER1145B, SER1148A, SER1148B, SER480A, SER480B, SER483A, SER483B, SER487A, SER487B, SER766A, SER766B, SER818A, SER818B, THR1080A, THR1080B, THR1150A, THR1150B, THR748A, THR748B, THR808A, THR808B, THR978A, THR978B, THR980A, THR980B, THR981B, TRP1147A, TRP1147B, TYR1140A, TYR1140B, TYR773B, TYR821A, TYR821B, TYR973A, TYR973B, TYR976A, TYR976B, VAL1154A, VAL1154B, VAL486A, VAL486B, VAL491A, VAL491B, VAL758A, VAL758B, VAL767A, VAL767B