3QVD

exposure of rubrerythrin from pyrococcus furiosus to peroxide, fifteen second time point.

• Total interactions analyzed: 28
• Total true interactions: 22
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 308
  • Norm. En. per Res.: -5.104
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-204.7721	51.8844	-1383.86	-1536.7477	308	50	52	51233	10	122	128
A-E	0.0	-5.0949	-6.8489	-11.9438	14	0	0	507	0	7	6
A-F	0.0	0.0	-0.0289	-0.0289	3	0	0	10	0	2	2
A-G	-46.0254	-56.9082	-116.478	-219.4116	44	6	0	3743	2	20	8
A-H	-5.5622	-21.7107	-78.7444	-106.0173	41	0	5	3326	2	8	10
B-C	-9.5294	23.7595	-33.4665	-19.2363	39	2	0	1571	4	43	51
B-E	0.0	-75.0904	-27.8614	-102.9518	39	3	0	2147	4	14	14
B-F	0.0	-8.9048	-7.6286	-16.5334	12	0	0	473	1	7	6
B-G	-18.4313	-3.6314	-81.4638	-103.5266	41	2	5	3458	2	8	10
B-H	-37.3069	-43.285	-107.951	-188.543	41	6	0	3575	0	20	8
C-D	-221.7701	50.1914	-1381.74	-1553.3187	308	35	53	51214	10	123	131
C-E	-45.3152	-57.3854	-115.534	-218.2346	43	6	0	3787	2	20	8
C-F	-22.0233	-31.5164	-79.0766	-132.6164	40	1	5	3413	2	9	10
C-G	-8.5358	-8.8333	-6.7492	-24.1182	15	2	0	487	1	7	6
C-H	-7.2533	-55.941	-46.102	-109.2962	40	12	0	2359	5	12	14
D-E	-10.0327	-3.6485	-78.706	-92.3872	41	2	5	3433	2	8	11
D-F	-28.0404	-47.4135	-110.761	-186.215	43	5	0	3618	1	20	8
D-G	0.0	0.0	-0.0017	-0.0017	2	0	0	2	0	2	2
D-H	-3.6885	-5.4554	-5.6458	-14.7897	17	2	0	572	0	7	6
E-F	-232.3816	25.7342	-1365.39	-1572.0373	308	51	52	51125	9	122	131
E-H	-8.4732	25.1744	-29.5421	-12.8409	39	5	0	1728	4	45	51
G-H	-224.2216	57.5558	-1379.5	-1546.1658	307	51	52	51308	10	124	131

Interface residues

• A-B: ALA103A, ALA103B, ALA110A, ALA110B, ALA113A, ALA113B, ALA118A, ALA118B, ALA124A, ALA124B, ALA128A, ALA128B, ALA149A, ALA149B, ALA15A, ALA15B, ALA17A, ALA17B, ALA22A, ALA22B, ALA30A, ALA30B, ALA33A, ALA33B, ALA42A, ALA42B, ALA47A, ALA47B, ALA49A, ALA49B, ALA51A, ALA51B, ALA56A, ALA56B, ALA62A, ALA62B, ALA94A, ALA94B, ALA95A, ALA95B, ARG105A, ARG105B, ARG122A, ARG122B, ARG25A, ARG25B, ARG46A, ARG46B, ARG5A, ARG5B, ASN40A, ASN40B, ASN58A, ASN58B, ASN72A, ASN72B, ASN92A, ASN92B, ASP133A, ASP133B, ASP151A, ASP151B, CYS142A, CYS142B, CYS145A, CYS145B, CYS160A, CYS160B, GLN35A, GLN35B, GLN74A, GLN74B, GLN98A, GLN98B, GLU100A, GLU100B, GLU102A, GLU102B, GLU112A, GLU112B, GLU114A, GLU114B, GLU119A, GLU119B, GLU126A, GLU126B, GLU129A, GLU129B, GLU132A, GLU132B, GLU135A, GLU135B, GLU13A, GLU13B, GLU14A, GLU14B, GLU171A, GLU171B, GLU19A, GLU19B, GLU31A, GLU31B, GLU34A, GLU34B, GLU36A, GLU36B, GLU52A, GLU52B, GLU71A, GLU71B, GLU78A, GLU78B, GLU80A, GLU80B, GLU83A, GLU83B, GLU96A, GLU96B, GLY131A, GLY131B, GLY146A, GLY146B, GLY18A, GLY18B, GLY37A, GLY37B, GLY64A, GLY64B, GLY67A, GLY67B, GLY76A, GLY76B, GLY79A, GLY79B, GLY99A, GLY99B, HIS108A, HIS108B, HIS117A, HIS117B, HIS23A, HIS23B, HIS55A, HIS55B, HIS59A, HIS59B, ILE116A, ILE116B, ILE134A, ILE134B, ILE136A, ILE136B, ILE141A, ILE141B, ILE144A, ILE144B, ILE28A, ILE28B, ILE41A, ILE41B, ILE48A, ILE48B, ILE61A, ILE61B, ILE77A, ILE77B, LEU111A, LEU111B, LEU120A, LEU120B, LEU12A, LEU12B, LEU27A, LEU27B, LEU44A, LEU44B, LEU63A, LEU63B, LEU66A, LEU66B, LEU73A, LEU73B, LYS101A, LYS101B, LYS10A, LYS10B, LYS115A, LYS115B, LYS123A, LYS123B, LYS125A, LYS125B, LYS127A, LYS127B, LYS130A, LYS130B, LYS137A, LYS137B, LYS138A, LYS138B, LYS166A, LYS166B, LYS32A, LYS32B, LYS43A, LYS43B, LYS4A, LYS4B, LYS57A, LYS57B, LYS65A, LYS65B, LYS68A, LYS68B, LYS93A, LYS93B, LYS9A, LYS9B, MET21A, MET21B, MET24A, MET24B, MET75A, MET75B, MET7A, MET7B, MET87A, MET87B, PHE11A, PHE11B, PHE167A, PHE167B, PHE16A, PHE16B, PHE170A, PHE170B, PHE29A, PHE29B, PHE38A, PHE38B, PHE45A, PHE45B, PHE53A, PHE53B, PHE60A, PHE60B, PHE82A, PHE82B, PHE97A, PHE97B, PRO143A, PRO143B, PRO39A, PRO39B, PRO70A, PRO70B, SER20A, SER20B, THR106A, THR106B, THR107A, THR107B, THR148A, THR148B, THR69A, THR69B, THR6A, THR6B, THR81A, THR81B, THR8A, THR8B, TYR109A, TYR109B, TYR121A, TYR121B, TYR140A, TYR140B, TYR147A, TYR147B, TYR26A, TYR26B, TYR50A, TYR50B, TYR88A, TYR88B, TYR91A, TYR91B, VAL104A, VAL104B, VAL139A, VAL139B, VAL150A, VAL150B, VAL159A, VAL159B, VAL168A, VAL168B, VAL169A, VAL169B, VAL2A, VAL2B, VAL3A, VAL3B, VAL54A, VAL54B, VAL90A, VAL90B
• A-E: ALA103A, ALA95A, GLN98A, GLU100A, GLU102A, GLU129E, GLU71E, GLY131E, GLY99A, LYS101A, LYS130E, LYS68E, PHE97A, PRO70E
• A-F: GLU36A, LYS101F, LYS32A
• A-G: ALA94A, ALA94G, ARG5A, ARG5G, ASN92A, ASN92G, GLU14A, GLU14G, GLU83A, GLU83G, GLU85A, GLU85G, GLU86A, GLU86G, LYS10A, LYS10G, LYS4A, LYS4G, LYS93A, LYS93G, LYS9A, LYS9G, MET7A, MET7G, MET87A, MET87G, PHE11A, PHE11G, PHE82A, PHE82G, PRO89A, PRO89G, THR6A, THR6G, THR8A, THR8G, TYR88A, TYR88G, TYR91A, TYR91G, VAL84A, VAL84G, VAL90A, VAL90G
• A-H: ALA94A, ALA94H, ALA95A, ALA95H, ASN92A, ASN92H, GLN98A, GLN98H, GLU14A, GLU14H, GLU85A, GLU85H, GLU86A, GLU86H, GLU96A, GLU96H, LEU111A, LEU111H, LYS10A, LYS10H, LYS93A, LYS93H, MET7A, MET7H, MET87A, MET87H, PHE11A, PHE11H, PHE82A, PHE82H, PHE97A, PHE97H, PRO89A, PRO89H, TYR88A, TYR88H, TYR91A, TYR91H, VAL84A, VAL90A, VAL90H
• B-C: ALA118B, ALA118C, ARG122B, ARG122C, GLN74B, GLN74C, GLU119B, GLU119C, GLU126B, GLU126C, GLU129B, GLU129C, GLU71B, GLU71C, GLU78B, GLU78C, GLU85B, GLU85C, GLU86B, GLU86C, ILE77B, ILE77C, LYS115B, LYS115C, LYS123C, LYS125B, LYS125C, LYS130B, LYS130C, PHE82B, PHE82C, PRO70B, PRO70C, PRO89B, PRO89C, THR81B, THR81C, VAL84B, VAL84C
• B-E: ALA128B, ALA128E, ARG5B, ARG5E, ASN72B, GLN74E, GLU129B, GLU129E, GLU71B, GLU71E, GLY131B, GLY131E, GLY64B, GLY64E, GLY67B, GLY67E, LEU63B, LEU63E, LEU66B, LEU66E, LYS125B, LYS125E, LYS130B, LYS130E, LYS4B, LYS4E, LYS65B, LYS65E, LYS68B, LYS68E, MET75B, PRO70B, PRO70E, THR6B, THR6E, VAL2B, VAL2E, VAL3B, VAL3E
• B-F: ALA103F, GLN98F, GLU100F, GLU102F, GLU129B, GLU71B, GLY99F, LYS101F, LYS130B, LYS68B, PHE97F, PRO70B
• B-G: ALA94B, ALA94G, ALA95B, ALA95G, ASN92B, ASN92G, GLN98B, GLN98G, GLU14B, GLU14G, GLU85B, GLU85G, GLU86B, GLU86G, GLU96B, GLU96G, LEU111B, LEU111G, LYS10B, LYS10G, LYS93B, LYS93G, MET7B, MET7G, MET87B, MET87G, PHE11B, PHE11G, PHE82B, PHE82G, PHE97B, PHE97G, PRO89B, PRO89G, TYR88B, TYR88G, TYR91B, TYR91G, VAL84G, VAL90B, VAL90G
• B-H: ALA94B, ALA94H, ARG5B, ARG5H, ASN92B, GLU14B, GLU14H, GLU83B, GLU83H, GLU85B, GLU85H, GLU86B, GLU86H, LYS10B, LYS10H, LYS4B, LYS4H, LYS93B, LYS93H, LYS9B, LYS9H, MET7B, MET7H, MET87B, MET87H, PHE11B, PHE11H, PHE82B, PHE82H, PRO89B, PRO89H, THR6B, THR6H, THR8B, THR8H, TYR88B, TYR88H, TYR91B, TYR91H, VAL90B, VAL90H
• C-D: ALA103C, ALA103D, ALA110C, ALA110D, ALA113C, ALA113D, ALA118C, ALA118D, ALA124C, ALA124D, ALA128C, ALA128D, ALA149C, ALA149D, ALA15C, ALA15D, ALA17C, ALA17D, ALA22C, ALA22D, ALA30C, ALA30D, ALA33C, ALA33D, ALA42C, ALA42D, ALA47C, ALA47D, ALA49C, ALA49D, ALA51C, ALA51D, ALA56C, ALA56D, ALA62C, ALA62D, ALA94C, ALA94D, ALA95C, ALA95D, ARG105C, ARG105D, ARG122C, ARG122D, ARG25C, ARG25D, ARG46C, ARG46D, ARG5C, ARG5D, ASN40C, ASN40D, ASN58C, ASN58D, ASN72C, ASN72D, ASN92C, ASN92D, ASP133C, ASP133D, ASP151C, ASP151D, CYS142C, CYS142D, CYS145C, CYS145D, CYS160C, CYS160D, GLN35C, GLN35D, GLN74C, GLN74D, GLN98C, GLN98D, GLU100C, GLU100D, GLU102C, GLU102D, GLU112C, GLU112D, GLU114C, GLU114D, GLU119C, GLU119D, GLU126C, GLU126D, GLU129C, GLU129D, GLU132C, GLU132D, GLU135C, GLU135D, GLU13C, GLU13D, GLU14C, GLU14D, GLU171C, GLU171D, GLU19C, GLU19D, GLU31C, GLU31D, GLU34C, GLU34D, GLU36C, GLU36D, GLU52C, GLU52D, GLU71C, GLU71D, GLU78C, GLU78D, GLU80C, GLU80D, GLU83C, GLU83D, GLU96C, GLU96D, GLY131C, GLY131D, GLY146C, GLY146D, GLY18C, GLY18D, GLY37C, GLY37D, GLY64C, GLY64D, GLY67C, GLY67D, GLY76C, GLY76D, GLY79C, GLY79D, GLY99C, GLY99D, HIS108C, HIS108D, HIS117C, HIS117D, HIS23C, HIS23D, HIS55C, HIS55D, HIS59C, HIS59D, ILE116C, ILE116D, ILE134C, ILE134D, ILE136C, ILE136D, ILE141C, ILE141D, ILE144C, ILE144D, ILE28C, ILE28D, ILE41C, ILE41D, ILE48C, ILE48D, ILE61C, ILE61D, ILE77C, ILE77D, LEU111C, LEU111D, LEU120C, LEU120D, LEU12C, LEU12D, LEU27C, LEU27D, LEU44C, LEU44D, LEU63C, LEU63D, LEU66C, LEU66D, LEU73C, LEU73D, LYS101C, LYS101D, LYS10C, LYS10D, LYS115C, LYS115D, LYS123C, LYS123D, LYS125C, LYS125D, LYS127C, LYS127D, LYS130C, LYS130D, LYS137C, LYS137D, LYS138C, LYS138D, LYS166C, LYS166D, LYS32C, LYS32D, LYS43C, LYS43D, LYS4C, LYS4D, LYS57C, LYS57D, LYS65C, LYS65D, LYS68C, LYS68D, LYS93C, LYS93D, LYS9C, LYS9D, MET21C, MET21D, MET24C, MET24D, MET75C, MET75D, MET7C, MET7D, MET87C, MET87D, PHE11C, PHE11D, PHE167C, PHE167D, PHE16C, PHE16D, PHE170C, PHE170D, PHE29C, PHE29D, PHE38C, PHE38D, PHE45C, PHE45D, PHE53C, PHE53D, PHE60C, PHE60D, PHE82C, PHE82D, PHE97C, PHE97D, PRO143C, PRO143D, PRO39C, PRO39D, PRO70C, PRO70D, SER20C, SER20D, THR106C, THR106D, THR107C, THR107D, THR148C, THR148D, THR69C, THR69D, THR6C, THR6D, THR81C, THR81D, THR8C, THR8D, TYR109C, TYR109D, TYR121C, TYR121D, TYR140C, TYR140D, TYR147C, TYR147D, TYR26C, TYR26D, TYR50C, TYR50D, TYR88C, TYR88D, TYR91C, TYR91D, VAL104C, VAL104D, VAL139C, VAL139D, VAL150C, VAL150D, VAL159C, VAL159D, VAL168C, VAL168D, VAL169C, VAL169D, VAL2C, VAL2D, VAL3C, VAL3D, VAL54C, VAL54D, VAL90C, VAL90D
• C-E: ALA94C, ALA94E, ARG5C, ARG5E, ASN92C, ASN92E, GLU14C, GLU14E, GLU83C, GLU83E, GLU85C, GLU85E, GLU86C, GLU86E, LYS10C, LYS10E, LYS4C, LYS4E, LYS93C, LYS93E, LYS9C, LYS9E, MET7C, MET7E, MET87C, MET87E, PHE11C, PHE11E, PHE82C, PHE82E, PRO89C, PRO89E, THR6C, THR6E, THR8C, THR8E, TYR88C, TYR88E, TYR91C, TYR91E, VAL84E, VAL90C, VAL90E
• C-F: ALA94C, ALA94F, ALA95C, ALA95F, ASN92C, ASN92F, GLN98C, GLN98F, GLU14C, GLU14F, GLU85C, GLU85F, GLU86C, GLU86F, GLU96C, GLU96F, LEU111C, LEU111F, LYS10C, LYS10F, LYS93C, LYS93F, MET7C, MET7F, MET87C, MET87F, PHE11C, PHE11F, PHE82C, PHE82F, PHE97C, PHE97F, PRO89C, PRO89F, TYR88C, TYR88F, TYR91C, TYR91F, VAL90C, VAL90F
• C-G: ALA103G, ALA95G, GLN98G, GLU100G, GLU102G, GLU129C, GLU71C, GLY99G, LYS101G, LYS130C, LYS32G, LYS4C, LYS68C, PHE97G, PRO70C
• C-H: ALA128C, ALA128H, ARG5C, ARG5H, ASN72C, ASN72H, GLN74C, GLU129C, GLU129H, GLU71C, GLU71H, GLY131C, GLY131H, GLY64C, GLY64H, GLY67C, GLY67H, LEU66C, LEU66H, LYS125C, LYS125H, LYS130C, LYS130H, LYS4C, LYS4H, LYS65C, LYS65H, LYS68C, LYS68H, MET75H, PRO70C, PRO70H, THR69C, THR6C, THR6H, THR8H, VAL2C, VAL2H, VAL3C, VAL3H
• D-E: ALA94D, ALA94E, ALA95D, ALA95E, ASN92D, ASN92E, GLN98D, GLN98E, GLU14D, GLU14E, GLU85D, GLU85E, GLU86D, GLU86E, GLU96D, GLU96E, LEU111D, LEU111E, LYS10D, LYS10E, LYS93D, LYS93E, MET7D, MET7E, MET87D, MET87E, PHE11D, PHE11E, PHE82D, PHE82E, PHE97D, PHE97E, PRO89D, PRO89E, TYR88D, TYR88E, TYR91D, TYR91E, VAL84E, VAL90D, VAL90E
• D-F: ALA94D, ALA94F, ARG5D, ARG5F, ASN92D, ASN92F, GLU14D, GLU14F, GLU83D, GLU83F, GLU85D, GLU85F, GLU86D, GLU86F, LYS10D, LYS10F, LYS4D, LYS4F, LYS93D, LYS93F, LYS9D, LYS9F, MET7D, MET7F, MET87D, MET87F, PHE11D, PHE11F, PHE82D, PHE82F, PRO89D, PRO89F, THR6D, THR6F, THR8D, THR8F, TYR88D, TYR88F, TYR91D, TYR91F, VAL84F, VAL90D, VAL90F
• D-G: GLU36G, LYS101D
• D-H: ALA103D, ALA95D, GLN98D, GLU100D, GLU102D, GLU129H, GLU36D, GLU71H, GLY99D, LYS101D, LYS130H, LYS32D, LYS4H, LYS68H, PHE97D, PRO70H, VAL104D
• E-F: ALA103E, ALA103F, ALA110E, ALA110F, ALA113E, ALA113F, ALA118E, ALA118F, ALA124E, ALA124F, ALA128E, ALA128F, ALA149E, ALA149F, ALA15E, ALA15F, ALA17E, ALA17F, ALA22E, ALA22F, ALA30E, ALA30F, ALA33E, ALA33F, ALA42E, ALA42F, ALA47E, ALA47F, ALA49E, ALA49F, ALA51E, ALA51F, ALA56E, ALA56F, ALA62E, ALA62F, ALA94E, ALA94F, ALA95E, ALA95F, ARG105E, ARG105F, ARG122E, ARG122F, ARG25E, ARG25F, ARG46E, ARG46F, ARG5E, ARG5F, ASN40E, ASN40F, ASN58E, ASN58F, ASN72E, ASN72F, ASN92E, ASN92F, ASP133E, ASP133F, ASP151E, ASP151F, CYS142E, CYS142F, CYS145E, CYS145F, CYS160E, CYS160F, GLN35E, GLN35F, GLN74E, GLN74F, GLN98E, GLN98F, GLU100E, GLU100F, GLU102E, GLU102F, GLU112E, GLU112F, GLU114E, GLU114F, GLU119E, GLU119F, GLU126E, GLU126F, GLU129E, GLU129F, GLU132E, GLU132F, GLU135E, GLU135F, GLU13E, GLU13F, GLU14E, GLU14F, GLU171E, GLU171F, GLU19E, GLU19F, GLU31E, GLU31F, GLU34E, GLU34F, GLU36E, GLU36F, GLU52E, GLU52F, GLU71E, GLU71F, GLU78E, GLU78F, GLU80E, GLU80F, GLU83E, GLU83F, GLU96E, GLU96F, GLY131E, GLY131F, GLY146E, GLY146F, GLY18E, GLY18F, GLY37E, GLY37F, GLY64E, GLY64F, GLY67E, GLY67F, GLY76E, GLY76F, GLY79E, GLY79F, GLY99E, GLY99F, HIS108E, HIS108F, HIS117E, HIS117F, HIS23E, HIS23F, HIS55E, HIS55F, HIS59E, HIS59F, ILE116E, ILE116F, ILE134E, ILE134F, ILE136E, ILE136F, ILE141E, ILE141F, ILE144E, ILE144F, ILE28E, ILE28F, ILE41E, ILE41F, ILE48E, ILE48F, ILE61E, ILE61F, ILE77E, ILE77F, LEU111E, LEU111F, LEU120E, LEU120F, LEU12E, LEU12F, LEU27E, LEU27F, LEU44E, LEU44F, LEU63E, LEU63F, LEU66E, LEU66F, LEU73E, LEU73F, LYS101E, LYS101F, LYS10E, LYS10F, LYS115E, LYS115F, LYS123E, LYS123F, LYS125E, LYS125F, LYS127E, LYS127F, LYS130E, LYS130F, LYS137E, LYS137F, LYS138E, LYS138F, LYS166E, LYS166F, LYS32E, LYS32F, LYS43E, LYS43F, LYS4E, LYS4F, LYS57E, LYS57F, LYS65E, LYS65F, LYS68E, LYS68F, LYS93E, LYS93F, LYS9E, LYS9F, MET21E, MET21F, MET24E, MET24F, MET75E, MET75F, MET7E, MET7F, MET87E, MET87F, PHE11E, PHE11F, PHE167E, PHE167F, PHE16E, PHE16F, PHE170E, PHE170F, PHE29E, PHE29F, PHE38E, PHE38F, PHE45E, PHE45F, PHE53E, PHE53F, PHE60E, PHE60F, PHE82E, PHE82F, PHE97E, PHE97F, PRO143E, PRO143F, PRO39E, PRO39F, PRO70E, PRO70F, SER20E, SER20F, THR106E, THR106F, THR107E, THR107F, THR148E, THR148F, THR69E, THR69F, THR6E, THR6F, THR81E, THR81F, THR8E, THR8F, TYR109E, TYR109F, TYR121E, TYR121F, TYR140E, TYR140F, TYR147E, TYR147F, TYR26E, TYR26F, TYR50E, TYR50F, TYR88E, TYR88F, TYR91E, TYR91F, VAL104E, VAL104F, VAL139E, VAL139F, VAL150E, VAL150F, VAL159E, VAL159F, VAL168E, VAL168F, VAL169E, VAL169F, VAL2E, VAL2F, VAL3E, VAL3F, VAL54E, VAL54F, VAL90E, VAL90F
• E-H: ALA118E, ALA118H, ARG122E, ARG122H, GLN74E, GLN74H, GLU119E, GLU119H, GLU126E, GLU126H, GLU129E, GLU129H, GLU71E, GLU71H, GLU78E, GLU78H, GLU85E, GLU85H, GLU86E, GLU86H, ILE77E, ILE77H, LEU111E, LYS115E, LYS115H, LYS125E, LYS125H, LYS130E, LYS130H, LYS93E, PHE82H, PRO70E, PRO70H, PRO89E, PRO89H, THR81E, THR81H, VAL84E, VAL84H
• G-H: ALA103G, ALA103H, ALA110G, ALA110H, ALA113G, ALA113H, ALA118G, ALA118H, ALA124G, ALA124H, ALA128G, ALA128H, ALA149G, ALA149H, ALA15G, ALA15H, ALA17G, ALA17H, ALA22G, ALA22H, ALA30G, ALA30H, ALA33G, ALA33H, ALA42G, ALA42H, ALA47G, ALA47H, ALA49G, ALA49H, ALA51G, ALA51H, ALA56G, ALA56H, ALA62G, ALA62H, ALA94G, ALA94H, ALA95G, ALA95H, ARG105G, ARG105H, ARG122G, ARG122H, ARG25G, ARG25H, ARG46G, ARG46H, ARG5G, ARG5H, ASN40G, ASN40H, ASN58G, ASN58H, ASN72G, ASN72H, ASN92G, ASN92H, ASP133G, ASP133H, ASP151G, ASP151H, CYS142G, CYS142H, CYS145G, CYS145H, CYS160G, CYS160H, GLN35G, GLN35H, GLN74G, GLN74H, GLN98G, GLN98H, GLU100G, GLU100H, GLU102G, GLU102H, GLU112G, GLU112H, GLU114G, GLU114H, GLU119G, GLU119H, GLU126G, GLU126H, GLU129G, GLU129H, GLU132G, GLU132H, GLU135G, GLU135H, GLU13G, GLU13H, GLU14G, GLU14H, GLU171G, GLU171H, GLU19G, GLU19H, GLU31G, GLU31H, GLU34G, GLU34H, GLU36G, GLU36H, GLU52G, GLU52H, GLU71G, GLU71H, GLU78H, GLU80G, GLU80H, GLU83G, GLU83H, GLU96G, GLU96H, GLY131G, GLY131H, GLY146G, GLY146H, GLY18G, GLY18H, GLY37G, GLY37H, GLY64G, GLY64H, GLY67G, GLY67H, GLY76G, GLY76H, GLY79G, GLY79H, GLY99G, GLY99H, HIS108G, HIS108H, HIS117G, HIS117H, HIS23G, HIS23H, HIS55G, HIS55H, HIS59G, HIS59H, ILE116G, ILE116H, ILE134G, ILE134H, ILE136G, ILE136H, ILE141G, ILE141H, ILE144G, ILE144H, ILE28G, ILE28H, ILE41G, ILE41H, ILE48G, ILE48H, ILE61G, ILE61H, ILE77G, ILE77H, LEU111G, LEU111H, LEU120G, LEU120H, LEU12G, LEU12H, LEU27G, LEU27H, LEU44G, LEU44H, LEU63G, LEU63H, LEU66G, LEU66H, LEU73G, LEU73H, LYS101G, LYS101H, LYS10G, LYS10H, LYS115G, LYS115H, LYS123G, LYS123H, LYS125G, LYS125H, LYS127G, LYS127H, LYS130G, LYS130H, LYS137G, LYS137H, LYS138G, LYS138H, LYS166G, LYS166H, LYS32G, LYS32H, LYS43G, LYS43H, LYS4G, LYS4H, LYS57G, LYS57H, LYS65G, LYS65H, LYS68G, LYS68H, LYS93G, LYS93H, LYS9G, LYS9H, MET21G, MET21H, MET24G, MET24H, MET75G, MET75H, MET7G, MET7H, MET87G, MET87H, PHE11G, PHE11H, PHE167G, PHE167H, PHE16G, PHE16H, PHE170G, PHE170H, PHE29G, PHE29H, PHE38G, PHE38H, PHE45G, PHE45H, PHE53G, PHE53H, PHE60G, PHE60H, PHE82G, PHE82H, PHE97G, PHE97H, PRO143G, PRO143H, PRO39G, PRO39H, PRO70G, PRO70H, SER20G, SER20H, THR106G, THR106H, THR107G, THR107H, THR148G, THR148H, THR69G, THR69H, THR6G, THR6H, THR81G, THR81H, THR8G, THR8H, TYR109G, TYR109H, TYR121G, TYR121H, TYR140G, TYR140H, TYR147G, TYR147H, TYR26G, TYR26H, TYR50G, TYR50H, TYR88G, TYR88H, TYR91G, TYR91H, VAL104G, VAL104H, VAL139G, VAL139H, VAL150G, VAL150H, VAL159G, VAL159H, VAL168G, VAL168H, VAL169G, VAL169H, VAL2G, VAL2H, VAL3G, VAL3H, VAL54G, VAL54H, VAL90G, VAL90H