3QRF

structure of a domain-swapped foxp3 dimer

• Total interactions analyzed: 45
• Total true interactions: 9
• Strongest Interaction:
  • Chains: F-G
  • Int. Res.: 155
  • Norm. En. per Res.: -5.8813
• Hub Node: N(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
N-F	-7.3228	1.6733	-19.5561	-25.2056	29	1	0	1338	0	13	14
N-G	-13.9277	-44.2723	-73.2937	-131.4937	49	3	0	3477	4	24	25
N-M	-5.0155	-10.5866	-156.165	-171.767	124	6	0	6954	0	22	25
N-H	0.0	17.9744	-21.2934	-3.319	13	0	0	860	0	4	15
F-G	-73.4357	-14.7727	-823.39	-911.5985	155	44	22	31677	4	37	55
F-M	0.0	17.8058	-20.9759	-3.1701	12	0	0	854	0	4	15
M-H	-7.2907	1.7449	-19.5972	-25.143	29	1	0	1332	0	13	14
M-I	-13.8686	-43.7032	-73.2	-130.7718	49	3	0	3465	4	24	25
H-I	-74.1327	-14.8653	-822.347	-911.3451	155	44	22	31693	4	37	55

Interface residues

• N-F: ALA524N, ARG358F, ARG369F, ARG466N, ARG529N, ARG537N, ASN361F, ASN523N, ASP534N, GLN357F, GLU355F, GLU362F, GLU465N, GLU527N, GLU532N, GLY531N, GLY536N, HIS365F, ILE526N, ILE535N, LEU360F, LEU528N, LYS538N, PHE473N, PRO354F, THR359F, THR368F, THR533N, TRP366F
• N-G: ALA404G, ALA463N, ARG337G, ARG397G, ARG466N, ARG529N, ARG537N, ARG541N, ARG665N, ARG667N, ASN539N, ASN657N, ASP464N, ASP534N, GLN669N, GLU399G, GLU401G, GLU465N, GLU527N, GLU532N, GLY403G, GLY531N, GLY536N, GLY663N, HIS471N, ILE526N, ILE535N, ILE661N, LEU528N, LEU577N, LYS402G, LYS530N, LYS538N, LYS614N, LYS664N, LYS666N, MET336G, PHE340G, PHE473N, PRO338G, PRO670N, SER400G, SER668N, THR462N, THR533N, THR540N, THR612N, TYR659N, VAL405G
• N-M: ARG411M, ARG411N, ARG510M, ARG510N, ARG556M, ARG556N, ARG582M, ARG582N, ARG651M, ARG651N, ASN508M, ASN508N, ASN565M, ASN565N, ASP584M, ASP584N, ASP586M, ASP586N, ASP617M, ASP617N, CYS588M, CYS588N, GLN404M, GLN404N, GLN415M, GLN415N, GLN444M, GLN444N, GLN583M, GLN583N, GLU398M, GLU398N, GLU409M, GLU409N, GLU413M, GLU413N, GLU552M, GLU552N, GLY406M, GLY406N, GLY447M, GLY447N, HIS446M, HIS446N, HIS672M, HIS672N, HIS676M, HIS676N, ILE412M, ILE412N, ILE467M, ILE467N, ILE557M, ILE557N, LEU401M, LEU401N, LEU410M, LEU410N, LEU445M, LEU445N, LEU560M, LEU560N, LEU589M, LEU589N, LYS655M, LYS655N, MET449M, MET449N, PHE673M, PHE673N, PRO396M, PRO396N, PRO400M, PRO400N, PRO653M, PRO653N, PRO677M, PRO677N, SER402M, SER402N, SER403M, SER403N, SER405M, SER405N, SER407M, SER407N, SER553M, SER553N, SER554M, SER554N, SER559M, SER559N, SER587M, SER587N, THR585M, THR585N, THR615M, THR615N, THR616M, THR616N, THR652M, THR652N, THR674M, THR674N, TRP399M, TRP399N, TYR408M, TYR408N, TYR448M, TYR448N, TYR675M, TYR675N, VAL395M, VAL395N, VAL414M, VAL414N, VAL442M, VAL442N, VAL558M, VAL558N, VAL654M, VAL654N, VAL678M, VAL678N
• N-H: ARG414H, ARG417H, ARG651N, ASN647N, GLU412H, HIS649N, ILE650N, LEU411H, LYS415H, LYS416H, LYS648N, PHE413H, VAL678N
• F-G: ALA343F, ALA343G, ALA349F, ALA349G, ALA353F, ALA353G, ALA372F, ALA372G, ALA379F, ALA379G, ALA384F, ALA384G, ALA404F, ALA404G, ARG337F, ARG337G, ARG347F, ARG347G, ARG358F, ARG358G, ARG369F, ARG369G, ARG375F, ARG375G, ARG386F, ARG386G, ARG397F, ARG397G, ARG414F, ARG414G, ARG417F, ASN361F, ASN361G, ASN376F, ASN376G, ASN383F, ASN383G, ASN388F, ASN388G, ASP409F, ASP409G, CYS394F, CYS394G, GLN357F, GLN357G, GLU352F, GLU352G, GLU355F, GLU355G, GLU362F, GLU362G, GLU399F, GLU399G, GLU401F, GLU410F, GLU410G, GLU412G, GLY403F, GLY403G, HIS365F, HIS365G, HIS377F, HIS377G, HIS387F, HIS387G, HIS392F, HIS392G, ILE346F, ILE346G, ILE350F, ILE350G, ILE363F, ILE363G, ILE385F, ILE385G, LEU345F, LEU345G, LEU351F, LEU351G, LEU360F, LEU360G, LEU389F, LEU389G, LEU391F, LEU391G, LEU411F, LEU411G, LYS356F, LYS356G, LYS382F, LYS382G, LYS402F, LYS402G, LYS416F, MET336F, MET336G, MET370F, MET370G, PHE340F, PHE340G, PHE367F, PHE367G, PHE371F, PHE371G, PHE373F, PHE373G, PHE374F, PHE374G, PHE395F, PHE395G, PHE413F, PHE413G, PRO338F, PRO338G, PRO339F, PRO339G, PRO354G, PRO378F, PRO378G, SER390F, SER390G, SER400F, SER400G, THR341F, THR341G, THR344F, THR344G, THR359F, THR359G, THR368F, THR368G, THR380F, THR380G, THR407F, THR407G, TRP348F, TRP348G, TRP366F, TRP366G, TRP381F, TRP381G, TRP406F, TRP406G, TYR342F, TYR342G, TYR364F, TYR364G, VAL396F, VAL396G, VAL398F, VAL398G, VAL405F, VAL405G, VAL408F, VAL408G
• F-M: ARG414F, ARG417F, ARG651M, ASN647M, GLU412F, HIS649M, LEU411F, LYS415F, LYS416F, LYS648M, PHE413F, VAL678M
• M-H: ALA524M, ARG358H, ARG369H, ARG466M, ARG529M, ARG537M, ASN361H, ASN523M, ASP534M, GLN357H, GLU355H, GLU362H, GLU465M, GLU527M, GLU532M, GLY531M, GLY536M, HIS365H, ILE526M, ILE535M, LEU360H, LEU528M, LYS538M, PHE473M, PRO354H, THR359H, THR368H, THR533M, TRP366H
• M-I: ALA404I, ALA463M, ARG337I, ARG397I, ARG466M, ARG529M, ARG537M, ARG541M, ARG665M, ARG667M, ASN539M, ASN657M, ASP464M, ASP534M, GLN669M, GLU399I, GLU401I, GLU465M, GLU527M, GLU532M, GLY403I, GLY531M, GLY536M, GLY663M, HIS471M, ILE526M, ILE535M, ILE661M, LEU528M, LEU577M, LYS402I, LYS530M, LYS538M, LYS614M, LYS664M, LYS666M, MET336I, PHE340I, PHE473M, PRO338I, PRO670M, SER400I, SER668M, THR462M, THR533M, THR540M, THR612M, TYR659M, VAL405I
• H-I: ALA343H, ALA343I, ALA349H, ALA349I, ALA353H, ALA353I, ALA372H, ALA372I, ALA379H, ALA379I, ALA384H, ALA384I, ALA404H, ALA404I, ARG337H, ARG337I, ARG347H, ARG347I, ARG358H, ARG358I, ARG369H, ARG369I, ARG375H, ARG375I, ARG386H, ARG386I, ARG397H, ARG397I, ARG414H, ARG414I, ARG417H, ASN361H, ASN361I, ASN376H, ASN376I, ASN383H, ASN383I, ASN388H, ASN388I, ASP409H, ASP409I, CYS394H, CYS394I, GLN357H, GLN357I, GLU352H, GLU352I, GLU355H, GLU355I, GLU362H, GLU362I, GLU399H, GLU399I, GLU401H, GLU410H, GLU410I, GLU412I, GLY403H, GLY403I, HIS365H, HIS365I, HIS377H, HIS377I, HIS387H, HIS387I, HIS392H, HIS392I, ILE346H, ILE346I, ILE350H, ILE350I, ILE363H, ILE363I, ILE385H, ILE385I, LEU345H, LEU345I, LEU351H, LEU351I, LEU360H, LEU360I, LEU389H, LEU389I, LEU391H, LEU391I, LEU411H, LEU411I, LYS356H, LYS356I, LYS382H, LYS382I, LYS402H, LYS402I, LYS416H, MET336H, MET336I, MET370H, MET370I, PHE340H, PHE340I, PHE367H, PHE367I, PHE371H, PHE371I, PHE373H, PHE373I, PHE374H, PHE374I, PHE395H, PHE395I, PHE413H, PHE413I, PRO338H, PRO338I, PRO339H, PRO339I, PRO354I, PRO378H, PRO378I, SER390H, SER390I, SER400H, SER400I, THR341H, THR341I, THR344H, THR344I, THR359H, THR359I, THR368H, THR368I, THR380H, THR380I, THR407H, THR407I, TRP348H, TRP348I, TRP366H, TRP366I, TRP381H, TRP381I, TRP406H, TRP406I, TYR342H, TYR342I, TYR364H, TYR364I, VAL396H, VAL396I, VAL398H, VAL398I, VAL405H, VAL405I, VAL408H, VAL408I