3QML

the structural analysis of sil1-bip complex reveals the mechanism for sil1 to function as a novel nucleotide exchange factor

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 141
  • Norm. En. per Res.: -3.6955
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-26.9752	-12.7423	-34.9847	-74.7022	34	3	0	1506	2	17	16
A-C	-80.8388	-111.4726	-328.761	-521.0725	141	14	0	13130	13	93	89
A-D	0.0	-30.8939	-33.4077	-64.3016	39	1	0	1500	2	13	8
B-D	-31.4016	-114.1093	-277.796	-423.3068	127	19	0	12321	10	91	85

Interface residues

• A-B: ALA199A, ALA203A, ALA304B, ARG201A, ASN125A, ASN197A, ASN301B, ASN302B, ASP126A, ASP144A, ASP198A, ASP206A, ASP297B, ASP300B, ASP334B, GLN200A, GLN202A, GLY121A, GLY295B, GLY335B, ILE296B, ILE336B, LYS123A, LYS146A, LYS205A, LYS291B, LYS303B, PHE196A, PHE332B, SER299B, SER331B, TYR195A, VAL298B, VAL333B
• A-C: ALA100A, ALA106A, ALA107A, ALA162C, ALA304A, ALA306A, ALA312A, ALA315A, ALA318A, ALA345A, ALA76A, ARG157C, ARG198C, ARG205C, ARG246C, ARG310A, ARG317A, ARG326A, ARG342C, ARG344A, ARG387A, ARG387C, ARG82A, ASN103A, ASN206C, ASN207C, ASN252C, ASN302A, ASN409A, ASN77A, ASN81A, ASP123C, ASP153C, ASP156C, ASP164C, ASP330A, ASP337A, ASP337C, ASP388C, ASP392C, ASP99A, CYS203C, GLN104A, GLN281C, GLN322A, GLN391C, GLN79A, GLU125C, GLU160C, GLU194C, GLU253C, GLU288C, GLU311A, GLU313A, GLU328A, GLU338C, GLU340A, GLU348A, GLU349A, GLU386C, GLU390C, GLU78A, GLY122C, GLY168C, GLY335A, GLY80A, HIS163C, HIS167C, HIS174C, HIS294A, HIS340C, ILE158C, ILE200C, ILE242C, ILE250C, ILE284C, ILE327A, ILE329A, ILE336A, ILE336C, ILE83A, LEU195C, LEU204C, LEU305A, LEU308A, LEU319A, LEU338A, LEU339C, LEU342A, LEU352A, LEU384C, LYS102A, LYS166C, LYS170C, LYS245C, LYS285C, LYS292C, LYS293A, LYS303A, LYS307A, LYS309A, LYS314A, LYS316A, LYS346A, LYS356A, LYS390A, MET159C, MET323A, PHE126C, PHE155C, PHE161C, PHE332A, PHE344C, PRO208C, PRO209C, PRO85A, SER127C, SER202C, SER249C, SER321A, SER324A, SER331A, SER335C, SER339A, SER393C, THR197C, THR201C, THR325A, THR341A, THR341C, THR343A, THR343C, THR389C, TYR124C, TYR165C, TYR169C, TYR61A, VAL105A, VAL199C, VAL210C, VAL333A
• A-D: ALA149D, ALA422A, ARG150D, ARG157D, ARG217A, ASN187D, ASN259A, ASN48A, ASP147D, ASP153D, ASP156D, ASP232A, GLN146D, GLN265A, GLN421A, GLU152D, GLU258A, GLU263A, GLY260A, GLY423A, ILE148D, ILE227A, LEU151D, LEU188D, LEU190D, LEU192D, LEU216A, LYS205A, PHE262A, PRO189D, SER144D, SER145D, SER154D, SER239D, THR191D, TYR49A, VAL261A, VAL424A, VAL52A
• B-D: ALA100B, ALA106B, ALA107B, ALA162D, ALA304B, ALA306B, ALA312B, ALA315B, ALA318B, ALA345B, ARG157D, ARG198D, ARG205D, ARG246D, ARG310B, ARG317B, ARG326B, ARG342D, ARG344B, ARG387B, ARG387D, ASN103B, ASN206D, ASN207D, ASN252D, ASN302B, ASN81B, ASP156D, ASP164D, ASP330B, ASP337B, ASP337D, ASP388D, ASP99B, CYS203D, GLN104B, GLN281D, GLN322B, GLN391D, GLN79B, GLU125D, GLU160D, GLU194D, GLU253D, GLU288D, GLU311B, GLU313B, GLU328B, GLU338D, GLU340B, GLU348B, GLU349B, GLU386D, GLU390D, GLU78B, GLY168D, GLY335B, GLY80B, HIS163D, HIS167D, HIS174D, HIS294B, HIS340D, ILE158D, ILE242D, ILE250D, ILE284D, ILE327B, ILE329B, ILE336B, ILE336D, ILE83B, LEU195D, LEU204D, LEU305B, LEU308B, LEU319B, LEU338B, LEU339D, LEU342B, LEU352B, LYS102B, LYS166D, LYS170D, LYS245D, LYS285D, LYS293B, LYS303B, LYS307B, LYS309B, LYS314B, LYS316B, LYS346B, LYS356B, LYS390B, MET159D, MET323B, PHE126D, PHE155D, PHE161D, PHE332B, PHE344D, PRO208D, PRO209D, PRO85B, SER202D, SER249D, SER324B, SER331B, SER335D, SER339B, SER393D, THR197D, THR201D, THR325B, THR341B, THR341D, THR343B, THR343D, THR389D, THR84B, TYR165D, TYR169D, TYR61B, VAL105B, VAL199D, VAL210D