3QLV

crystal structure of the gluk2/gluk5 (glur6/ka2) atd tetramer assembly

• Total interactions analyzed: 45
• Total true interactions: 13
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 158
  • Norm. En. per Res.: -2.7599
• Hub Node: C(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-72.831	4.3384	-343.593	-412.0856	153	21	16	15550	4	57	44
A-F	-5.5822	7.0389	-46.0387	-44.5819	38	6	0	2243	1	2	9
B-D	-22.1433	2.5848	-302.986	-322.5444	153	17	14	14533	4	53	44
B-G	0.0	0.0	-0.0007	-0.0007	2	0	0	2	0	0	0
C-D	-4.8395	-21.9233	-127.256	-154.0187	60	2	3	4878	4	24	6
C-F	0.0	0.0	-0.0012	-0.0012	2	0	0	3	0	0	2
C-J	0.0	0.0	-0.0008	-0.0008	2	0	0	2	0	1	0
E-F	-54.8218	7.3713	-388.608	-436.0585	158	45	16	16855	4	57	47
E-I	0.0	0.0	-0.1991	-0.1991	8	0	0	50	0	0	0
F-H	0.0	-22.6635	-104.478	-127.1415	60	0	2	4536	3	23	6
F-I	0.0	2.4975	-9.1032	-6.6057	30	0	0	686	0	8	7
G-H	-44.4921	12.8405	-339.824	-371.4756	153	29	16	15580	4	56	44
I-J	-17.172	10.9028	-263.484	-269.7532	146	7	14	13420	1	52	44

Interface residues

• A-C: ALA147A, ALA149A, ALA160C, ALA314A, ALA318A, ALA60C, ALA82A, ALA84C, ALA86C, ALA93C, ARG113A, ARG153C, ARG154A, ARG160A, ARG163C, ARG167C, ARG171C, ARG172A, ARG178A, ARG318C, ARG53A, ASN110C, ASN165C, ASN317C, ASN53C, ASN85C, ASN92C, ASP109C, ASP112C, ASP146C, ASP147C, ASP175A, ASP176A, ASP190A, ASP54A, ASP56C, ASP61A, CYS146A, CYS151A, CYS315A, CYS316C, CYS64A, CYS65C, CYS91C, GLN106C, GLN134C, GLN155C, GLN172C, GLN315C, GLN56A, GLN65A, GLN88C, GLU105A, GLU150A, GLU156A, GLU156C, GLU157A, GLU167A, GLU186A, GLU192C, GLU58A, GLU59C, GLU93A, GLY150C, GLY161A, HIS105C, HIS319C, HIS80C, HIS89A, ILE152C, ILE158C, ILE164A, ILE170C, ILE187A, ILE90A, ILE90C, LEU112A, LEU144A, LEU151C, LEU152A, LEU153A, LEU154C, LEU155A, LEU157C, LEU158A, LEU163A, LEU166C, LEU168C, LEU169A, LEU173C, LEU174A, LEU183A, LEU314C, LEU54C, LEU67A, LEU68C, LEU94C, LYS104C, LYS111C, LYS148A, LYS159C, LYS166A, LYS169C, LYS320C, LYS62C, LYS94A, MET173A, MET63A, PHE162A, PHE58C, PRO107A, PRO161C, PRO321C, PRO81A, SER108C, SER113C, SER143A, SER148C, SER162C, SER165A, SER170A, SER317A, SER55A, SER57C, SER61C, SER80A, SER81C, SER82C, SER83A, SER83C, SER85A, SER89C, THR106A, THR140C, THR142C, THR149C, THR168A, THR316A, THR59A, THR60A, THR62A, THR86A, TRP103C, TYR145C, TYR164C, TYR55C, TYR57A, VAL107C, VAL141C, VAL143C, VAL159A, VAL171A, VAL87C
• A-F: ALA142A, ALA219A, ARG188A, ARG323F, ARG327F, ASN138A, ASN42F, ASP190A, GLN305F, GLN308F, GLU167A, GLU334F, HIS3F, LEU331F, LYS135A, LYS191A, LYS222A, LYS348F, MET309F, PHE137A, PHE220A, PHE306F, PHE324F, PHE328F, PRO140A, PRO307F, SER136A, SER141A, SER193A, SER330F, THR168A, THR194A, THR310F, THR326F, THR43F, TYR139A, TYR221A, VAL192A
• B-D: ALA147B, ALA149B, ALA160D, ALA314B, ALA318B, ALA60D, ALA82B, ALA84D, ALA86D, ALA93D, ARG113B, ARG153D, ARG154B, ARG160B, ARG163D, ARG167D, ARG171D, ARG172B, ARG178B, ARG318D, ARG53B, ASN110D, ASN165D, ASN317D, ASN53D, ASN85D, ASN92D, ASP109D, ASP112D, ASP146D, ASP147D, ASP175B, ASP176B, ASP190B, ASP54B, ASP56D, ASP61B, CYS146B, CYS151B, CYS315B, CYS316D, CYS64B, CYS65D, CYS91D, GLN106D, GLN134D, GLN155D, GLN172D, GLN315D, GLN56B, GLN65B, GLN88D, GLU105B, GLU150B, GLU156B, GLU156D, GLU157B, GLU167B, GLU186B, GLU192D, GLU58B, GLU59D, GLU93B, GLY150D, GLY161B, HIS105D, HIS319D, HIS80D, HIS89B, ILE152D, ILE158D, ILE164B, ILE170D, ILE187B, ILE90B, ILE90D, LEU112B, LEU144B, LEU151D, LEU152B, LEU153B, LEU154D, LEU155B, LEU157D, LEU158B, LEU163B, LEU166D, LEU168D, LEU169B, LEU173D, LEU174B, LEU183B, LEU314D, LEU54D, LEU67B, LEU68D, LEU94D, LYS104D, LYS111D, LYS148B, LYS159D, LYS166B, LYS169D, LYS320D, LYS62D, LYS94B, MET173B, MET63B, PHE162B, PHE58D, PRO107B, PRO161D, PRO81B, SER108D, SER113D, SER123D, SER143B, SER148D, SER162D, SER165B, SER170B, SER317B, SER55B, SER57D, SER61D, SER80B, SER81D, SER82D, SER83B, SER83D, SER85B, SER89D, THR106B, THR140D, THR142D, THR149D, THR168B, THR316B, THR59B, THR60B, THR62B, THR86B, TRP103D, TYR145D, TYR164D, TYR55D, TYR57B, VAL107D, VAL141D, VAL143D, VAL159B, VAL171B, VAL87D
• B-G: ARG342G, ARG363B
• C-D: ALA211C, ALA211D, ALA213C, ALA213D, ARG189C, ARG189D, ARG239C, ARG239D, ASP179C, ASP179D, GLN210C, GLN210D, GLU219C, GLU219D, GLU236C, GLU236D, GLU365C, GLU365D, GLY215C, GLY215D, GLY242C, GLY242D, LEU212C, LEU212D, LYS181C, LYS181D, LYS185C, LYS185D, LYS188C, LYS188D, LYS191C, LYS191D, LYS209C, LYS209D, MET214C, MET214D, MET216C, MET216D, MET217C, MET217D, PHE193C, PHE193D, PRO182C, PRO182D, PRO237C, PRO237D, SER241C, SER241D, THR218C, THR218D, TYR220C, TYR220D, TYR221C, TYR221D, TYR238C, TYR238D, TYR240C, TYR240D, VAL243C, VAL243D
• C-F: ARG189C, ARG37F
• C-J: ALA377C, ALA377J
• E-F: ALA147E, ALA149E, ALA160F, ALA314E, ALA318E, ALA60F, ALA82E, ALA84F, ALA86F, ALA93F, ARG113E, ARG153F, ARG154E, ARG160E, ARG163F, ARG167F, ARG171F, ARG172E, ARG178E, ARG318F, ARG53E, ASN110F, ASN165F, ASN317F, ASN53F, ASN85F, ASN92F, ASP109F, ASP112F, ASP146F, ASP147F, ASP175E, ASP176E, ASP190E, ASP54E, ASP56F, ASP61E, CYS146E, CYS151E, CYS315E, CYS316F, CYS64E, CYS65F, CYS91E, CYS91F, GLN106F, GLN134F, GLN155F, GLN172F, GLN315F, GLN56E, GLN65E, GLN88F, GLU105E, GLU150E, GLU156E, GLU156F, GLU157E, GLU167E, GLU186E, GLU192F, GLU58E, GLU59F, GLU93E, GLY150F, GLY161E, GLY92E, HIS105F, HIS319F, HIS80F, HIS89E, ILE152F, ILE158F, ILE164E, ILE170F, ILE187E, ILE90E, ILE90F, LEU112E, LEU144E, LEU151F, LEU152E, LEU153E, LEU154F, LEU155E, LEU157F, LEU158E, LEU163E, LEU166F, LEU168F, LEU169E, LEU173F, LEU174E, LEU183E, LEU54F, LEU67E, LEU68F, LEU94F, LYS104F, LYS111F, LYS139F, LYS148E, LYS159F, LYS166E, LYS169F, LYS320F, LYS62F, LYS94E, MET173E, MET63E, PHE162E, PHE58F, PRO107E, PRO161F, PRO321F, PRO81E, SER108F, SER113F, SER123F, SER143E, SER148F, SER162F, SER165E, SER170E, SER317E, SER55E, SER57F, SER61F, SER80E, SER81F, SER82F, SER83E, SER83F, SER85E, SER89F, THR106E, THR140F, THR142F, THR149F, THR168E, THR316E, THR59E, THR60E, THR62E, THR86E, TRP103F, TYR145F, TYR164F, TYR55F, TYR57E, VAL107F, VAL141F, VAL143F, VAL159E, VAL171E, VAL192E, VAL87E, VAL87F
• E-I: ARG178E, ARG188E, ASN138I, ASP189E, LYS185E, MET380I, PHE220I, THR181E
• F-H: ALA211F, ALA211H, ALA213F, ALA213H, ARG189F, ARG189H, ARG239F, ARG239H, ASP179F, ASP179H, GLN210F, GLN210H, GLU219F, GLU219H, GLU236F, GLU236H, GLU365F, GLU365H, GLY215F, GLY215H, GLY242F, GLY242H, LEU212F, LEU212H, LYS181F, LYS181H, LYS185F, LYS185H, LYS188F, LYS188H, LYS191F, LYS191H, LYS209F, LYS209H, MET214F, MET214H, MET216F, MET216H, MET217F, MET217H, PHE193F, PHE193H, PRO182F, PRO182H, PRO237F, PRO237H, SER241F, SER241H, THR218F, THR218H, TYR220F, TYR220H, TYR221F, TYR221H, TYR238F, TYR238H, TYR240F, TYR240H, VAL243F, VAL243H
• F-I: ALA219I, ALA377F, ARG163F, ARG188I, ARG363I, ARG367I, ASN165F, ASN244I, ASP131F, ASP241I, GLN134F, GLU213I, GLU240I, GLY215I, GLY379F, LEU214I, LEU380F, LYS137F, LYS139F, LYS348F, MET216I, PHE135F, PRO376F, SER212I, SER218I, SER242I, SER243I, SER378F, THR217I, TYR164F
• G-H: ALA142G, ALA147G, ALA149G, ALA160H, ALA314G, ALA318G, ALA60H, ALA82G, ALA84H, ALA86H, ALA93H, ARG113G, ARG153H, ARG154G, ARG160G, ARG163H, ARG167H, ARG171H, ARG172G, ARG178G, ARG318H, ARG53G, ASN110H, ASN165H, ASN317H, ASN53H, ASN85H, ASN92H, ASP109H, ASP112H, ASP146H, ASP147H, ASP175G, ASP176G, ASP190G, ASP54G, ASP56H, ASP61G, CYS146G, CYS151G, CYS315G, CYS316H, CYS64G, CYS65H, CYS91H, GLN106H, GLN134H, GLN155H, GLN172H, GLN315H, GLN56G, GLN65G, GLN88H, GLU105G, GLU150G, GLU156G, GLU156H, GLU157G, GLU167G, GLU186G, GLU192H, GLU58G, GLU59H, GLU93G, GLY150H, GLY161G, HIS105H, HIS319H, HIS80H, HIS89G, ILE152H, ILE158H, ILE164G, ILE170H, ILE187G, ILE90G, ILE90H, LEU112G, LEU144G, LEU151H, LEU152G, LEU153G, LEU154H, LEU155G, LEU157H, LEU158G, LEU163G, LEU166H, LEU168H, LEU169G, LEU173H, LEU174G, LEU183G, LEU314H, LEU54H, LEU67G, LEU68H, LEU94H, LYS104H, LYS111H, LYS139H, LYS148G, LYS159H, LYS166G, LYS169H, LYS62H, LYS94G, MET173G, MET63G, PHE162G, PHE58H, PRO107G, PRO161H, PRO81G, SER108H, SER113H, SER143G, SER148H, SER162H, SER165G, SER170G, SER317G, SER55G, SER57H, SER61H, SER80G, SER81H, SER82H, SER83G, SER83H, SER85G, SER89H, THR106G, THR140H, THR142H, THR149H, THR168G, THR316G, THR59G, THR60G, THR62G, THR86G, TRP103H, TYR145H, TYR164H, TYR55H, TYR57G, VAL107H, VAL141H, VAL143H, VAL159G, VAL171G, VAL87H
• I-J: ALA149I, ALA160J, ALA314I, ALA318I, ALA60J, ALA82I, ALA84J, ALA86J, ALA93J, ARG113I, ARG153J, ARG154I, ARG160I, ARG163J, ARG167J, ARG171J, ARG172I, ARG178I, ARG318J, ARG53I, ASN110J, ASN165J, ASN317J, ASN85J, ASN92J, ASP109J, ASP112J, ASP146J, ASP147J, ASP175I, ASP176I, ASP190I, ASP54I, ASP56J, ASP61I, CYS146I, CYS151I, CYS315I, CYS316J, CYS64I, CYS65J, CYS91J, GLN106J, GLN155J, GLN172J, GLN315J, GLN56I, GLN65I, GLN88J, GLU105I, GLU150I, GLU156I, GLU156J, GLU157I, GLU167I, GLU186I, GLU192J, GLU58I, GLU59J, GLU93I, GLY150J, GLY161I, HIS105J, HIS319J, HIS80J, HIS89I, ILE152J, ILE158J, ILE164I, ILE170J, ILE90I, ILE90J, LEU112I, LEU144I, LEU151J, LEU152I, LEU153I, LEU154J, LEU155I, LEU157J, LEU158I, LEU163I, LEU166J, LEU168J, LEU169I, LEU173J, LEU174I, LEU183I, LEU54J, LEU67I, LEU68J, LEU94J, LYS104J, LYS111J, LYS148I, LYS159J, LYS166I, LYS169J, LYS62J, LYS94I, MET173I, MET63I, PHE162I, PHE58J, PRO107I, PRO161J, PRO81I, SER108J, SER113J, SER123J, SER143I, SER148J, SER162J, SER165I, SER170I, SER317I, SER55I, SER57J, SER61J, SER80I, SER81J, SER82J, SER83I, SER83J, SER85I, SER89J, THR106I, THR140J, THR142J, THR149J, THR168I, THR316I, THR59I, THR60I, THR62I, THR86I, TRP103J, TYR145J, TYR164J, TYR55J, TYR57I, VAL107J, VAL141J, VAL159I, VAL171I, VAL87J