3QHS

crystal structure of full-length hfq from escherichia coli

• Total interactions analyzed: 66
• Total true interactions: 30
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 77
  • Norm. En. per Res.: -4.228
• Hub Node: B(7)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-40.0841	-8.3538	-228.869	-277.3069	72	7	8	9426	1	4	7
A-F	-36.1358	-3.8541	-205.689	-245.6789	74	11	6	8584	1	5	8
A-G	-16.2164	0.0	-37.5448	-53.7612	28	5	0	1845	0	0	1
A-L	0.0	0.0	-4.5779	-4.5779	16	0	0	395	0	0	2
B-C	-48.7524	-13.0228	-208.787	-270.5622	75	6	7	8870	1	4	8
B-G	0.0	0.0	-24.8704	-24.8704	14	0	1	897	0	0	1
B-H	0.0	0.0	-11.0323	-11.0323	11	0	0	452	0	0	0
B-I	0.0	0.0	-0.385	-0.385	7	0	0	68	0	0	0
B-J	0.0	0.0	-2.261	-2.261	13	0	0	189	0	0	1
B-K	0.0	0.0	-4.3026	-4.3026	13	0	0	213	0	0	1
B-L	0.0	0.0	-0.7919	-0.7919	12	0	0	161	0	0	0
C-D	-47.7562	-9.2179	-218.25	-275.2241	80	8	6	9347	1	4	8
C-G	0.0	0.0	-0.0015	-0.0015	2	0	0	1	0	0	0
C-H	0.0	0.0	-25.227	-25.227	14	0	0	1136	0	0	1
C-I	0.0	0.7993	-14.3143	-13.515	22	0	0	1038	0	0	1
C-J	0.0	0.0	-0.0562	-0.0562	5	0	0	26	0	0	0
D-E	-45.8979	-14.4902	-207.817	-268.205	76	11	7	8816	2	4	8
D-H	0.0	0.0	-16.6855	-16.6855	16	0	0	709	0	0	2
E-F	-60.7794	-12.4802	-252.298	-325.5577	77	15	8	9922	2	5	8
E-H	0.0	0.0	-0.509	-0.509	8	0	0	110	0	0	0
F-G	0.0	0.0	-1.7459	-1.7459	13	0	0	249	0	0	2
F-H	0.0	0.0	-0.0029	-0.0029	2	0	0	4	0	0	0
G-H	-42.8646	10.2451	-218.393	-251.0124	73	12	7	9429	0	4	7
G-I	0.0	0.0	-0.0014	-0.0014	2	0	0	1	0	0	2
G-L	-52.6553	10.3699	-222.035	-264.3203	71	8	5	8957	0	5	8
H-I	-49.5456	3.1633	-206.816	-253.1982	70	7	6	8757	1	4	8
H-J	0.0	0.0	-0.0014	-0.0014	2	0	0	1	0	0	2
I-J	-34.5125	-11.2845	-224.77	-270.5671	73	11	6	9362	2	5	8
J-K	-27.5741	-15.8369	-218.117	-261.528	70	4	7	9096	1	4	8
K-L	-42.4997	-10.1531	-222.017	-274.6698	71	5	7	9171	1	4	8

Interface residues

• A-B: ALA58A, ALA58B, ARG66A, ASN28A, ASN28B, ASN48B, ASP40A, ASP40B, ASP9A, GLN41A, GLN41B, GLN52B, GLN5A, GLN8A, GLU37B, GLY29A, GLY29B, HIS57A, HIS57B, HIS70A, ILE24A, ILE24B, ILE30A, ILE30B, ILE36A, ILE44A, ILE44B, ILE59A, ILE59B, LEU12A, LEU15A, LEU26A, LEU26B, LEU32B, LEU45B, LEU46B, LEU7A, LYS31A, LYS47B, LYS56A, LYS56B, MET53B, PHE11A, PHE39A, PHE39B, PHE42A, PHE42B, PRO10A, PRO64A, PRO67A, SER23A, SER38B, SER51B, SER60A, SER65A, SER69A, SER6A, THR49B, THR61A, TYR25A, TYR55A, TYR55B, VAL20A, VAL27A, VAL27B, VAL43A, VAL43B, VAL50B, VAL54B, VAL62A, VAL63A, VAL68A
• A-F: ALA58A, ALA58F, ARG66F, ASN13F, ASN28A, ASN28F, ASN48A, ASP40A, ASP40F, ASP9F, GLN41A, GLN41F, GLN52A, GLN5F, GLN8F, GLU37A, GLY29A, GLY29F, HIS57A, HIS57F, HIS70F, HIS71F, ILE24A, ILE24F, ILE30A, ILE30F, ILE36A, ILE36F, ILE44A, ILE44F, ILE59A, ILE59F, LEU12F, LEU15F, LEU26A, LEU26F, LEU32A, LEU45A, LEU46A, LEU7F, LYS47A, LYS56A, LYS56F, MET53A, PHE11F, PHE39A, PHE39F, PHE42A, PHE42F, PRO10F, PRO64F, PRO67F, SER23F, SER38A, SER51A, SER60F, SER65F, SER69F, SER6F, THR49A, THR61F, TYR25F, TYR55A, TYR55F, VAL22F, VAL27A, VAL27F, VAL43A, VAL43F, VAL50A, VAL54A, VAL62F, VAL63F, VAL68F
• A-G: ASN28A, ASN28G, ASN48A, ASN48G, GLN33A, GLN33G, GLN52G, GLY29A, GLY29G, ILE24G, ILE30A, ILE30G, LEU26A, LEU26G, LEU32A, LEU32G, LYS31A, LYS31G, SER23A, SER23G, THR49A, THR49G, THR61A, TYR25A, TYR25G, VAL22G, VAL27A, VAL50G
• A-L: ARG66A, GLN33A, GLN33L, GLY29L, LYS31A, LYS31L, PRO21A, PRO64A, SER23A, SER65A, THR61L, TYR25A, TYR25L, VAL22A, VAL63A, VAL63L
• B-C: ALA58B, ALA58C, ARG66B, ASN13B, ASN28B, ASN28C, ASN48C, ASN73B, ASP40B, ASP40C, ASP9B, GLN41B, GLN41C, GLN52C, GLN5B, GLN8B, GLU37C, GLY29B, GLY29C, HIS57B, HIS57C, HIS71B, ILE24B, ILE24C, ILE30B, ILE30C, ILE36B, ILE36C, ILE44B, ILE44C, ILE59B, ILE59C, LEU12B, LEU15B, LEU26B, LEU26C, LEU32C, LEU45C, LEU46C, LEU7B, LYS47C, LYS56B, LYS56C, MET53C, PHE11B, PHE39B, PHE39C, PHE42B, PHE42C, PRO10B, PRO64B, PRO67B, SER23B, SER38C, SER51C, SER60B, SER65B, SER69B, SER6B, SER72B, THR49C, THR61B, TYR25B, TYR55B, TYR55C, VAL20B, VAL27B, VAL27C, VAL43B, VAL43C, VAL50C, VAL54C, VAL62B, VAL63B, VAL68B
• B-G: ASN28B, ASN28G, GLY29B, GLY29G, ILE30B, ILE30G, LEU26B, LEU26G, LEU32B, LYS31B, LYS31G, TYR25G, VAL27B, VAL27G
• B-H: ASN28B, ASN28H, GLY29B, GLY29H, ILE30B, ILE30H, LEU26B, LEU26H, LYS31B, TYR25B, VAL27B
• B-I: ASN28I, GLY29I, ILE30I, LYS31B, THR61B, TYR25B, VAL27I
• B-J: ARG66B, ASN28J, GLN33B, GLY29J, ILE30J, LYS31B, LYS31J, PRO64B, SER23B, SER65B, TYR25B, VAL27J, VAL63B
• B-K: ASN28K, ASN48B, GLN33B, GLY29K, ILE30K, LEU26K, LYS31B, PRO21B, SER23B, SER65B, THR49B, TYR25K, VAL27K
• B-L: ASN28L, ASN48B, GLN33B, GLY29L, ILE30B, ILE30L, LEU32B, LYS31B, LYS31L, THR49B, VAL27L, VAL50B
• C-D: ALA58C, ALA58D, ARG16D, ARG66C, ASN13D, ASN28C, ASN28D, ASN48D, ASN73C, ASP40C, ASP40D, ASP9C, ASP9D, GLN41C, GLN41D, GLN52D, GLN5C, GLN8C, GLU37D, GLY29C, GLY29D, GLY4C, HIS57C, HIS57D, HIS70C, HIS71C, ILE24C, ILE24D, ILE30C, ILE30D, ILE36C, ILE44C, ILE44D, ILE59C, ILE59D, LEU12C, LEU15C, LEU26C, LEU26D, LEU32D, LEU45D, LEU46D, LEU7C, LYS31C, LYS47D, LYS56C, LYS56D, MET53D, PHE11C, PHE39C, PHE39D, PHE42C, PHE42D, PRO10C, PRO64C, PRO67C, SER23C, SER38D, SER51D, SER60C, SER65C, SER69C, SER6C, SER72C, THR49D, THR61C, TYR25C, TYR55C, TYR55D, VAL20C, VAL27C, VAL27D, VAL43C, VAL43D, VAL50D, VAL54C, VAL54D, VAL62C, VAL63C, VAL68C
• C-G: ASN28C, TYR25G
• C-H: ASN28C, ASN28H, GLN33H, GLY29C, GLY29H, ILE30C, ILE30H, LEU26C, LEU26H, LYS31C, LYS31H, TYR25C, TYR25H, VAL27C
• C-I: ASN28I, ASN48C, ASN48I, GLN33C, GLN33I, GLN52I, GLY29C, GLY29I, GLY34C, ILE30C, ILE30I, LEU26C, LEU32C, LEU32I, LYS31C, LYS31I, PRO21C, SER23C, SER23I, SER65C, THR49C, TYR25I
• C-J: ASN48C, ILE30J, LYS31J, THR49C, VAL50C
• D-E: ALA58D, ALA58E, ARG66D, ASN13D, ASN28D, ASN28E, ASN48E, ASP40D, ASP40E, ASP9D, GLN41D, GLN41E, GLN52E, GLN5D, GLN8D, GLU37E, GLY29D, GLY29E, HIS57D, HIS57E, HIS70D, HIS71D, ILE24D, ILE24E, ILE30D, ILE30E, ILE36D, ILE44D, ILE44E, ILE59D, ILE59E, LEU12D, LEU15D, LEU26D, LEU26E, LEU32E, LEU45E, LEU46E, LEU7D, LYS31D, LYS47E, LYS56D, LYS56E, MET53E, PHE11D, PHE39D, PHE39E, PHE42D, PHE42E, PRO10D, PRO64D, PRO67D, SER23D, SER38E, SER51E, SER60D, SER65D, SER69D, SER6D, SER72D, THR49E, THR61D, TYR25D, TYR55D, TYR55E, VAL20D, VAL27D, VAL27E, VAL43D, VAL43E, VAL50E, VAL54D, VAL54E, VAL62D, VAL63D, VAL68D
• D-H: ARG66H, ASN28D, ASN48H, GLN33H, GLY29D, ILE30D, LEU26D, LEU32H, LYS31D, LYS31H, PRO21H, SER23H, SER65H, TYR25D, TYR25H, VAL27D
• E-F: ALA58E, ALA58F, ARG16F, ARG66E, ASN13E, ASN28E, ASN28F, ASN48F, ASP40E, ASP40F, ASP9E, GLN41E, GLN41F, GLN52F, GLN5E, GLN8E, GLU37F, GLY29E, GLY29F, HIS57E, HIS57F, HIS70E, HIS71E, ILE24E, ILE24F, ILE30E, ILE30F, ILE36E, ILE36F, ILE44E, ILE44F, ILE59E, ILE59F, LEU12E, LEU15E, LEU26E, LEU26F, LEU32F, LEU45F, LEU46F, LEU7E, LYS31E, LYS47F, LYS56E, LYS56F, MET53F, PHE11E, PHE39E, PHE39F, PHE42E, PHE42F, PRO10E, PRO64E, PRO67E, SER23E, SER38F, SER51F, SER60E, SER65E, SER69E, SER6E, THR49F, THR61E, TYR25E, TYR55E, TYR55F, VAL20E, VAL27E, VAL27F, VAL43E, VAL43F, VAL50F, VAL54E, VAL54F, VAL62E, VAL63E, VAL68E
• E-H: ASN28E, ASN48H, GLN33H, GLY29E, ILE30E, LYS31E, THR49H, TYR25E
• F-G: ARG66G, ASN28F, GLN33G, GLY29F, ILE30F, LYS31F, LYS31G, PRO21G, SER23G, SER65G, THR61F, TYR25F, VAL27F
• F-H: ILE30F, THR49H
• G-H: ALA58G, ALA58H, ARG66G, ASN28G, ASN28H, ASN48H, ASP40G, ASP40H, ASP9G, GLN41G, GLN41H, GLN52H, GLN5G, GLN8G, GLU37H, GLY29G, GLY29H, HIS57G, HIS57H, HIS70G, ILE24G, ILE24H, ILE30G, ILE30H, ILE36G, ILE44G, ILE44H, ILE59G, ILE59H, LEU12G, LEU15G, LEU26G, LEU26H, LEU32H, LEU45H, LEU46H, LEU7G, LYS31G, LYS31H, LYS47H, LYS56G, LYS56H, MET53H, PHE11G, PHE39G, PHE39H, PHE42G, PHE42H, PRO10G, PRO64G, PRO67G, SER23G, SER38H, SER51H, SER60G, SER65G, SER69G, SER6G, THR49H, THR61G, TYR25G, TYR55G, TYR55H, VAL20G, VAL27G, VAL27H, VAL43H, VAL50H, VAL54G, VAL54H, VAL62G, VAL63G, VAL68G
• G-I: ASN28I, VAL27G
• G-L: ALA58G, ALA58L, ARG66L, ASN13G, ASN28G, ASN28L, ASN48G, ASP40G, ASP9G, ASP9L, GLN41G, GLN41L, GLN52G, GLN5L, GLN8L, GLU37G, GLY29G, GLY29L, HIS57G, HIS57L, HIS70L, HIS71L, ILE24G, ILE24L, ILE30G, ILE30L, ILE36L, ILE44G, ILE44L, ILE59G, ILE59L, LEU12G, LEU12L, LEU15L, LEU26G, LEU26L, LEU32G, LEU45G, LEU46G, LEU7L, LYS47G, LYS56G, LYS56L, MET53G, PHE11L, PHE39G, PHE39L, PHE42G, PRO10L, PRO64L, PRO67L, SER23L, SER38G, SER51G, SER60L, SER65L, SER69L, SER6L, THR49G, THR61L, TYR25L, TYR55G, TYR55L, VAL27G, VAL27L, VAL43G, VAL50G, VAL54G, VAL62L, VAL63L, VAL68L
• H-I: ALA58H, ALA58I, ARG16I, ARG66H, ASN13H, ASN28H, ASN28I, ASN48I, ASP40I, ASP9H, GLN41H, GLN41I, GLN52I, GLN8H, GLU37I, GLY29H, GLY29I, HIS57H, HIS57I, HIS70H, HIS71H, ILE24H, ILE24I, ILE30H, ILE30I, ILE36H, ILE44H, ILE44I, ILE59H, ILE59I, LEU12H, LEU15H, LEU26H, LEU26I, LEU32I, LEU45I, LEU46I, LEU7H, LYS47I, LYS56H, LYS56I, MET53I, PHE11H, PHE39H, PHE39I, PHE42I, PRO10H, PRO64H, PRO67H, SER23H, SER38I, SER51I, SER60H, SER65H, SER69H, SER6H, THR49I, THR61H, TYR25H, TYR55H, TYR55I, VAL20H, VAL27H, VAL27I, VAL43I, VAL50I, VAL54I, VAL62H, VAL63H, VAL68H
• H-J: ASN28J, VAL27H
• I-J: ALA58I, ALA58J, ARG66I, ASN13I, ASN28I, ASN28J, ASN48J, ASP40I, ASP40J, ASP9I, GLN41I, GLN41J, GLN52J, GLN5I, GLN8I, GLU37J, GLY29I, GLY29J, HIS57I, HIS57J, HIS70I, HIS71I, ILE24I, ILE24J, ILE30I, ILE30J, ILE36I, ILE44I, ILE44J, ILE59I, ILE59J, LEU12I, LEU15I, LEU26I, LEU26J, LEU32J, LEU45J, LEU46J, LEU7I, LYS47J, LYS56I, LYS56J, MET53J, PHE11I, PHE39I, PHE39J, PHE42I, PHE42J, PRO10I, PRO64I, PRO67I, SER23I, SER38J, SER51J, SER60I, SER65I, SER69I, SER6I, THR49J, THR61I, TYR25I, TYR55I, TYR55J, VAL20I, VAL27I, VAL27J, VAL43I, VAL43J, VAL50J, VAL54J, VAL62I, VAL63I, VAL68I
• J-K: ALA58J, ALA58K, ARG16K, ARG66J, ASN13J, ASN28J, ASN28K, ASN48K, ASP40J, ASP40K, ASP9J, GLN41J, GLN41K, GLN52K, GLN8J, GLU37K, GLY29J, GLY29K, HIS57J, HIS57K, HIS70J, ILE24J, ILE24K, ILE30J, ILE30K, ILE36J, ILE44J, ILE44K, ILE59J, ILE59K, LEU12J, LEU15J, LEU26J, LEU26K, LEU32K, LEU45K, LEU46K, LEU7J, LYS31J, LYS47K, LYS56J, LYS56K, MET53K, PHE11J, PHE39J, PHE39K, PHE42K, PRO10J, PRO64J, PRO67J, SER38K, SER51K, SER60J, SER65J, SER69J, SER6J, THR49K, THR61J, TYR25J, TYR55J, TYR55K, VAL20J, VAL27J, VAL27K, VAL43K, VAL50K, VAL54K, VAL62J, VAL63J, VAL68J
• K-L: ALA58K, ALA58L, ARG16L, ARG66K, ASN13K, ASN28K, ASN28L, ASN48L, ASP40L, ASP9K, GLN41K, GLN41L, GLN52L, GLN8K, GLU37L, GLY29K, GLY29L, HIS57K, HIS57L, HIS70K, HIS71K, ILE24K, ILE24L, ILE30K, ILE30L, ILE36K, ILE44K, ILE44L, ILE59K, ILE59L, LEU12K, LEU15K, LEU26K, LEU26L, LEU32L, LEU45L, LEU46L, LEU7K, LYS31K, LYS47L, LYS56K, LYS56L, MET53L, PHE11K, PHE39K, PHE39L, PHE42L, PRO10K, PRO64K, PRO67K, SER23K, SER38L, SER51L, SER60K, SER65K, SER6K, SER72K, THR49L, THR61K, TYR25K, TYR55K, TYR55L, VAL20K, VAL27K, VAL27L, VAL43L, VAL50L, VAL54L, VAL62K, VAL63K, VAL68K