3QGA

3.0 a model of iron containing urease urea2b2 from helicobacter mustelae

• Total interactions analyzed: 66
• Total true interactions: 31
• Strongest Interaction:
  • Chains: F-I
  • Int. Res.: 214
  • Norm. En. per Res.: -5.1067
• Hub Node: F(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-238.4308	-65.4161	-830.757	-1134.6039	227	35	9	30167	13	65	61
A-D	-40.722	-62.4696	-125.74	-228.9316	62	14	5	5160	6	28	27
A-G	-35.4494	-57.7336	-120.073	-213.256	61	12	5	5047	5	28	27
A-I	-167.5113	-77.2968	-568.04	-812.8482	210	25	7	21349	5	69	50
C-D	-175.1308	-75.3695	-564.154	-814.6544	203	24	7	21236	6	66	49
C-F	-190.5984	-141.0385	-745.45	-1077.0869	212	37	7	26463	10	62	76
C-I	-169.9315	-140.2748	-749.926	-1060.1322	216	27	8	26365	10	65	76
C-L	0.0	-6.189	-0.0539	-6.2429	5	0	0	23	0	7	4
D-F	-257.802	-58.5171	-835.157	-1151.4761	228	45	9	30329	13	65	61
D-G	-34.6808	-59.0002	-122.213	-215.894	62	9	5	5135	6	28	27
D-L	0.0	18.1804	-81.5953	-63.4149	47	1	2	4003	1	22	20
D-M	0.0	0.0	-0.0021	-0.0021	2	0	0	2	0	2	4
F-G	-171.9962	-71.4439	-556.547	-799.9871	202	21	7	21126	6	69	50
F-I	-189.6618	-140.6734	-762.507	-1092.8422	214	31	8	26598	10	65	77
F-J	-12.0779	18.5947	-79.7822	-73.2654	48	3	2	3975	1	22	19
F-L	-46.5897	-30.2634	-117.063	-193.9161	81	16	0	4581	8	48	48
F-R	0.0	-6.3001	-0.0608	-6.3609	5	0	0	25	0	8	4
G-I	-243.528	-61.8362	-850.032	-1155.3963	228	39	9	30429	12	63	61
G-J	0.0	0.0	-0.002	-0.002	2	0	0	2	0	2	4
J-L	-245.4362	-71.5376	-822.732	-1139.7058	229	39	9	30135	13	64	61
J-M	-42.4749	-62.3254	-121.341	-226.1413	62	14	5	5082	6	28	27
J-P	-40.6578	-59.5056	-117.566	-217.7294	62	14	5	5111	6	28	27
J-R	-191.7167	-76.9244	-566.07	-834.7112	204	26	7	21292	5	68	49
L-M	-161.4076	-76.5226	-554.594	-792.5243	204	22	7	21265	5	70	49
L-O	-185.1134	-144.6786	-742.09	-1071.882	215	32	7	26245	10	63	76
L-R	-191.5471	-139.3706	-751.543	-1082.4607	216	35	7	26636	10	65	77
M-O	-243.6933	-64.285	-839.65	-1147.6284	229	40	9	30325	11	64	61
M-P	-43.2564	-62.6165	-126.837	-232.7098	61	13	5	5159	6	28	27
O-P	-182.3784	-74.9353	-558.342	-815.6557	205	22	7	21102	5	66	49
O-R	-176.0197	-141.7191	-751.633	-1069.3718	213	37	8	26390	10	64	77
P-R	-255.9718	-64.297	-838.366	-1158.6348	229	42	9	30336	12	65	61

Interface residues

• A-C: ALA107A, ALA113A, ALA122A, ALA16A, ALA206A, ALA20A, ALA29C, ALA35A, ALA37A, ALA41A, ALA439C, ALA464C, ALA46C, ALA560C, ALA562C, ALA85A, ARG165A, ARG21A, ARG21C, ARG23A, ARG475C, ARG51C, ARG564C, ARG5C, ASN100C, ASN10C, ASN121A, ASN172A, ASN199A, ASN203A, ASN31A, ASN437C, ASN463C, ASN58C, ASN71C, ASN76A, ASN86A, ASP102C, ASP103A, ASP104A, ASP105C, ASP115A, ASP117A, ASP167A, ASP18C, ASP24C, ASP26C, ASP34C, ASP395C, ASP461C, ASP80A, GLN104C, GLN32A, GLN470C, GLN56C, GLN6C, GLN8A, GLU109A, GLU119A, GLU149A, GLU18A, GLU30C, GLU34A, GLU40C, GLU41C, GLU458C, GLU52C, GLU7A, GLU7C, GLU84A, GLU9A, GLY106C, GLY108A, GLY123A, GLY124C, GLY13C, GLY142A, GLY163A, GLY171A, GLY17A, GLY17C, GLY190A, GLY191A, GLY197A, GLY200A, GLY204A, GLY23C, GLY39C, GLY45C, GLY460C, GLY47C, GLY53C, GLY55C, GLY73A, GLY75A, GLY82A, HIS140A, HIS144A, HIS146A, HIS185A, ILE110A, ILE118A, ILE126A, ILE126C, ILE168A, ILE187A, ILE189A, ILE195A, ILE196A, ILE205A, ILE36A, ILE39A, ILE43A, ILE50C, LEU120A, LEU12A, LEU13A, LEU166A, LEU174A, LEU202A, LEU22C, LEU27C, LEU30A, LEU42C, LEU561C, LEU73C, LEU81A, LEU93A, LYS101C, LYS106A, LYS10A, LYS111A, LYS116A, LYS124A, LYS164A, LYS193A, LYS194A, LYS19C, LYS22A, LYS29A, LYS2C, LYS384C, LYS43C, LYS444C, LYS48C, LYS4C, LYS6A, LYS82C, LYS92A, LYS97C, MET103C, MET125C, MET198A, MET1C, MET3C, MET44A, MET459C, MET54C, MET71A, MET77A, PHE105A, PHE112A, PHE11A, PHE145A, PHE147A, PHE440C, PHE441C, PHE44C, PHE567C, PHE568C, PRO14C, PRO169A, PRO188A, PRO33A, PRO438C, PRO469C, PRO471C, PRO5A, PRO60C, PRO72A, PRO79A, SER114A, SER143A, SER170A, SER192A, SER40A, SER462C, SER465C, SER563C, SER57C, SER59C, THR11C, THR15C, THR16C, THR173A, THR25C, THR36C, THR468C, THR49C, THR4A, THR566C, THR91A, THR95A, TRP28C, TYR12C, TYR14A, TYR15A, TYR38A, TYR38C, TYR473C, TYR565C, TYR8C, VAL107C, VAL141A, VAL19A, VAL20C, VAL31C, VAL37C, VAL443C, VAL466C, VAL472C, VAL70A, VAL74A, VAL78A, VAL83A, VAL94A, VAL9C
• A-D: ALA16A, ALA16D, ALA20A, ALA35A, ALA37A, ALA41D, ALA47D, ALA85D, ARG21D, ARG23A, ARG48D, ARG49D, ASN31A, ASN86D, ASP45D, GLN32A, GLN8D, GLU18A, GLU18D, GLU26A, GLU34A, GLU46D, GLU69A, GLU7D, GLU9A, GLU9D, GLY17A, GLY17D, GLY27A, GLY50D, HIS42D, ILE36A, LEU12A, LEU12D, LEU13A, LEU13D, LEU28A, LEU30A, LEU3D, LYS10D, LYS22A, LYS24A, LYS29A, LYS2D, LYS51D, MET44D, MET71A, MET77A, PHE11D, PRO33A, PRO5D, PRO79A, PRO88D, THR4D, TYR14D, TYR15A, TYR15D, VAL19A, VAL19D, VAL70A, VAL74A, VAL78A
• A-G: ALA16A, ALA16G, ALA20G, ALA35G, ALA37G, ALA41A, ALA47A, ALA85A, ARG21A, ARG23G, ARG48A, ARG49A, ASN31G, ASN86A, ASP45A, GLN32G, GLN8A, GLU18A, GLU18G, GLU26G, GLU34G, GLU46A, GLU69G, GLU7A, GLU9A, GLU9G, GLY17A, GLY17G, GLY27G, GLY50A, HIS42A, ILE36G, LEU12A, LEU12G, LEU13A, LEU13G, LEU28G, LEU30G, LEU3A, LYS10A, LYS22G, LYS24G, LYS29G, LYS2A, LYS51A, MET44A, MET71G, MET77G, PHE11A, PRO33G, PRO79G, PRO88A, THR4A, TYR14A, TYR15A, TYR15G, VAL19A, VAL19G, VAL70G, VAL74G, VAL78G
• A-I: 2172CB4.6062, 3171CB8.4900, 7171CB4.4802, ALA147I, ALA149I, ALA150A, ALA153A, ALA178A, ALA229I, ALA254I, ALA263I, ALA311I, ALA368I, ALA41A, ALA439I, ALA47A, ALA556I, ALA55A, ALA560I, ALA562I, ALA85A, ARG152A, ARG158A, ARG175A, ARG262I, ARG328I, ARG367I, ARG374I, ARG475I, ARG48A, ARG564I, ASN133A, ASN150I, ASN151A, ASN199A, ASN203A, ASN252I, ASN308I, ASN437I, ASN538I, ASN86A, ASN97A, ASP231I, ASP249I, ASP258I, ASP259I, ASP284I, ASP315I, ASP45A, ASP80A, ASP89A, CYS320I, GLN142I, GLN143I, GLN205I, GLN363I, GLN377I, GLN470I, GLN56A, GLN8A, GLU149A, GLU18A, GLU253I, GLU312I, GLU370I, GLU458I, GLU540I, GLU558I, GLU7A, GLU84A, GLU9A, GLY135A, GLY142A, GLY177A, GLY179A, GLY197A, GLY200A, GLY224I, GLY255I, GLY366I, GLY369I, GLY460I, GLY50A, GLY82A, GLY90A, HIS140A, HIS144A, HIS146A, HIS221A, HIS232I, HIS281I, HIS313I, HIS322I, ILE176A, ILE196A, ILE230I, ILE303I, ILE307I, ILE327I, ILE338I, ILE343I, LEU12A, LEU139A, LEU13A, LEU148I, LEU154A, LEU166A, LEU174A, LEU201A, LEU314I, LEU317I, LEU3A, LEU561I, LEU57A, LEU81A, LEU93A, LYS10A, LYS134A, LYS137A, LYS217A, LYS2A, LYS2A5, LYS325I, LYS381I, LYS444I, LYS446I, LYS52A, LYS6A, LYS92A, MET198A, MET316I, MET318I, MET365I, MET44A, MET459I, MET58A, PHE11A, PHE144I, PHE145A, PHE147A, PHE223A, PHE440I, PHE456I, PHE542I, PHE567I, PHE568I, PHE87A, PRO136A, PRO145I, PRO227I, PRO283I, PRO301I, PRO304I, PRO373I, PRO445I, PRO471I, PRO539I, PRO555I, PRO5A, PRO79A, PRO88A, SER138A, SER143A, SER200I, SER201I, SER202I, SER228I, SER282I, SER334I, SER457I, SER563I, THR146I, THR173A, THR225I, THR226I, THR250I, THR260I, THR287I, THR300I, THR302I, THR306I, THR309I, THR319I, THR4A, THR53A, THR557I, THR566I, THR91A, THR95A, TRP98A, TYR14A, TYR15A, TYR256I, TYR305I, TYR473I, TYR474I, TYR565I, VAL141A, VAL251I, VAL257I, VAL285I, VAL310I, VAL443I, VAL472I, VAL537I, VAL54A, VAL559I, VAL83A, VAL94A, VAL96A
• C-D: ALA147C, ALA149C, ALA150D, ALA153D, ALA178D, ALA229C, ALA254C, ALA263C, ALA311C, ALA368C, ALA41D, ALA439C, ALA47D, ALA556C, ALA55D, ALA560C, ALA562C, ALA85D, ARG152D, ARG158D, ARG175D, ARG262C, ARG328C, ARG367C, ARG374C, ARG475C, ARG48D, ARG564C, ASN133D, ASN150C, ASN151D, ASN199D, ASN203D, ASN252C, ASN308C, ASN437C, ASN86D, ASN97D, ASP231C, ASP249C, ASP258C, ASP259C, ASP284C, ASP315C, ASP45D, ASP80D, ASP89D, CYS320C, GLN142C, GLN143C, GLN205C, GLN363C, GLN377C, GLN470C, GLN56D, GLN8D, GLU149D, GLU18D, GLU253C, GLU312C, GLU370C, GLU458C, GLU540C, GLU558C, GLU7D, GLU84D, GLU9D, GLY135D, GLY142D, GLY179D, GLY197D, GLY200D, GLY224C, GLY255C, GLY366C, GLY369C, GLY460C, GLY50D, GLY82D, GLY90D, HIS140D, HIS144D, HIS146D, HIS221D, HIS232C, HIS281C, HIS313C, HIS322C, ILE176D, ILE196D, ILE230C, ILE303C, ILE307C, ILE327C, ILE338C, ILE343C, LEU12D, LEU139D, LEU13D, LEU148C, LEU154D, LEU166D, LEU174D, LEU201D, LEU314C, LEU317C, LEU323C, LEU3D, LEU561C, LEU57D, LEU81D, LEU93D, LYS10D, LYS134D, LYS137D, LYS2D, LYS325C, LYS444C, LYS446C, LYS52D, LYS6D, LYS92D, MET198D, MET316C, MET318C, MET365C, MET44D, MET459C, MET58D, PHE11D, PHE144C, PHE145D, PHE147D, PHE223D, PHE440C, PHE456C, PHE542C, PHE567C, PHE568C, PHE87D, PRO136D, PRO145C, PRO227C, PRO283C, PRO301C, PRO304C, PRO373C, PRO445C, PRO471C, PRO539C, PRO555C, PRO5D, PRO79D, PRO88D, SER138D, SER143D, SER200C, SER201C, SER202C, SER228C, SER282C, SER334C, SER457C, SER563C, THR146C, THR173D, THR225C, THR226C, THR250C, THR260C, THR287C, THR300C, THR302C, THR306C, THR309C, THR319C, THR4D, THR53D, THR557C, THR566C, THR91D, THR95D, TRP98D, TYR14D, TYR15D, TYR256C, TYR305C, TYR473C, TYR474C, TYR565C, VAL141D, VAL251C, VAL257C, VAL285C, VAL310C, VAL443C, VAL472C, VAL537C, VAL54D, VAL559C, VAL83D, VAL94D, VAL96D
• C-F: ALA119F, ALA121F, ALA147C, ALA168C, ALA184C, ALA185C, ALA204C, ALA229C, ALA254C, ALA364C, ALA368C, ALA431F, ALA464F, ALA46F, ALA484F, ARG180C, ARG183C, ARG203C, ARG326C, ARG367C, ARG374C, ARG475F, ARG510C, ARG510F, ARG51F, ASN10F, ASN150C, ASN167C, ASN177C, ASN199C, ASN463F, ASN58F, ASN89F, ASP164C, ASP222C, ASP249C, ASP315C, ASP324C, ASP361C, ASP461F, ASP487F, ASP61F, ASP66F, CYS320C, GLN142C, GLN143C, GLN205C, GLN209C, GLN363C, GLN56F, GLU118F, GLU123F, GLU186C, GLU187C, GLU187F, GLU208C, GLU221C, GLU253C, GLU312C, GLU370C, GLU458F, GLU476F, GLU509C, GLU509F, GLU52F, GLU7F, GLY114F, GLY116F, GLY122F, GLY158C, GLY159C, GLY161C, GLY165C, GLY174C, GLY196C, GLY198C, GLY224C, GLY366C, GLY369C, GLY451F, GLY452F, GLY45F, GLY460F, GLY479F, GLY47F, GLY482F, GLY507C, GLY53F, GLY90F, HIS137C, HIS179C, HIS220C, HIS232C, HIS247C, HIS313C, HIS321C, HIS322C, HIS480F, HIS481F, ILE171C, ILE230C, ILE447F, ILE448F, ILE449F, ILE50F, ILE69F, ILE87F, LEU120F, LEU139C, LEU178C, LEU182C, LEU194C, LEU206C, LEU219C, LEU317C, LEU323C, LEU506C, LEU508C, LEU65F, LEU67F, LYS197C, LYS43F, LYS446F, LYS450F, LYS483C, LYS483F, LYS485C, LYS485F, LYS48F, LYS503C, LYS511F, LYS88F, LYS91F, MET125F, MET181C, MET316C, MET318C, MET365C, MET453F, MET459F, MET477F, MET54F, PHE138C, PHE144C, PHE217C, PHE44F, PHE456F, PHE478F, PHE486C, PHE486F, PRO141C, PRO145C, PRO162C, PRO173C, PRO227C, PRO301C, PRO373C, PRO467F, PRO469F, PRO60F, SER140C, SER200C, SER201C, SER202C, SER228C, SER360C, SER362C, SER457F, SER462F, SER465F, SER57F, SER59F, THR117F, THR11F, THR136C, THR146C, THR160C, THR166C, THR169C, THR172C, THR225C, THR226C, THR248C, THR250C, THR300C, THR319C, THR468F, THR488F, THR49F, THR566C, THR64F, THR70F, TRP176C, TRP223C, TYR188C, TYR473F, TYR474F, VAL112F, VAL113F, VAL115F, VAL163C, VAL175C, VAL192C, VAL207C, VAL251C, VAL371C, VAL435F, VAL454F, VAL455F, VAL466F, VAL472F, VAL68F
• C-I: ALA119C, ALA121C, ALA147I, ALA168I, ALA184I, ALA185I, ALA204I, ALA229I, ALA254I, ALA364I, ALA368I, ALA431C, ALA464C, ALA46C, ALA484C, ARG180I, ARG183I, ARG203I, ARG326I, ARG367I, ARG374I, ARG475C, ARG510C, ARG510I, ARG51C, ASN10C, ASN150I, ASN167I, ASN177I, ASN199I, ASN463C, ASN58C, ASN89C, ASP164I, ASP222I, ASP249I, ASP315I, ASP324I, ASP361I, ASP461C, ASP487C, ASP61C, ASP66C, CYS320I, GLN142I, GLN143I, GLN205I, GLN209I, GLN363I, GLN56C, GLU118C, GLU123C, GLU186I, GLU187C, GLU187I, GLU208I, GLU221I, GLU253I, GLU312I, GLU370I, GLU458C, GLU476C, GLU509C, GLU509I, GLU52C, GLU7C, GLY114C, GLY116C, GLY122C, GLY158I, GLY159I, GLY161I, GLY165I, GLY174I, GLY196I, GLY198I, GLY224I, GLY279I, GLY280I, GLY366I, GLY369I, GLY451C, GLY452C, GLY45C, GLY460C, GLY479C, GLY47C, GLY482C, GLY507I, GLY53C, GLY90C, HIS137I, HIS179I, HIS220I, HIS232I, HIS247I, HIS313I, HIS321I, HIS322I, HIS480C, HIS481C, ILE171I, ILE230I, ILE447C, ILE448C, ILE449C, ILE50C, ILE69C, ILE87C, LEU120C, LEU139I, LEU178I, LEU182I, LEU194I, LEU206I, LEU219I, LEU317I, LEU323I, LEU42C, LEU506I, LEU508I, LEU65C, LEU67C, LYS197I, LYS43C, LYS446C, LYS450C, LYS483C, LYS483I, LYS485C, LYS485I, LYS48C, LYS503I, LYS511C, LYS88C, LYS91C, MET125C, MET181I, MET316I, MET318I, MET365I, MET453C, MET459C, MET477C, MET54C, PHE138I, PHE144I, PHE217I, PHE44C, PHE456C, PHE478C, PHE486C, PHE486I, PHE568I, PRO141I, PRO145I, PRO162I, PRO173I, PRO227I, PRO301I, PRO373I, PRO467C, PRO469C, PRO60C, SER140I, SER200I, SER201I, SER202I, SER228I, SER360I, SER362I, SER457C, SER462C, SER465C, SER57C, SER59C, THR117C, THR11C, THR136I, THR146I, THR160I, THR166I, THR169I, THR172I, THR225I, THR226I, THR248I, THR250I, THR300I, THR319I, THR468C, THR488C, THR49C, THR566I, THR64C, THR70C, TRP176I, TRP223I, TYR188I, TYR473C, TYR474C, VAL112C, VAL113C, VAL115C, VAL163I, VAL175I, VAL192I, VAL207I, VAL251I, VAL371I, VAL435C, VAL454C, VAL455C, VAL466C, VAL472C, VAL68C
• C-L: ALA204C, ARG203C, ARG203L, ASP238L, GLU239L
• D-F: ALA107D, ALA113D, ALA122D, ALA16D, ALA206D, ALA20D, ALA29F, ALA35D, ALA37D, ALA41D, ALA439F, ALA464F, ALA46F, ALA560F, ALA562F, ALA85D, ARG165D, ARG21D, ARG21F, ARG23D, ARG475F, ARG51F, ARG564F, ARG5F, ASN100F, ASN10F, ASN121D, ASN172D, ASN199D, ASN203D, ASN31D, ASN437F, ASN463F, ASN58F, ASN71F, ASN76D, ASN86D, ASP102F, ASP103D, ASP104D, ASP105F, ASP115D, ASP117D, ASP167D, ASP18F, ASP24F, ASP26F, ASP34F, ASP395F, ASP461F, ASP80D, GLN104F, GLN32D, GLN470F, GLN56F, GLN6F, GLN8D, GLU109D, GLU119D, GLU123F, GLU149D, GLU18D, GLU30F, GLU34D, GLU40F, GLU41F, GLU458F, GLU52F, GLU7D, GLU7F, GLU84D, GLU9D, GLY106F, GLY108D, GLY123D, GLY124F, GLY13F, GLY142D, GLY163D, GLY171D, GLY17D, GLY17F, GLY190D, GLY191D, GLY197D, GLY200D, GLY204D, GLY23F, GLY39F, GLY45F, GLY460F, GLY47F, GLY53F, GLY55F, GLY73D, GLY75D, GLY82D, HIS140D, HIS144D, HIS146D, HIS185D, ILE110D, ILE118D, ILE126D, ILE126F, ILE168D, ILE187D, ILE189D, ILE195D, ILE196D, ILE205D, ILE36D, ILE39D, ILE43D, ILE50F, LEU120D, LEU12D, LEU13D, LEU166D, LEU174D, LEU202D, LEU22F, LEU27F, LEU30D, LEU42F, LEU561F, LEU73F, LEU81D, LEU93D, LYS101F, LYS106D, LYS10D, LYS111D, LYS116D, LYS124D, LYS164D, LYS193D, LYS194D, LYS19F, LYS22D, LYS29D, LYS2F, LYS384F, LYS43F, LYS444F, LYS48F, LYS4F, LYS6D, LYS82F, LYS92D, LYS97F, MET103F, MET125F, MET198D, MET1F, MET3F, MET44D, MET459F, MET54F, MET71D, MET77D, PHE105D, PHE112D, PHE11D, PHE145D, PHE147D, PHE440F, PHE441F, PHE44F, PHE567F, PHE568F, PRO14F, PRO169D, PRO188D, PRO33D, PRO438F, PRO469F, PRO471F, PRO5D, PRO60F, PRO72D, PRO79D, SER114D, SER143D, SER170D, SER192D, SER40D, SER462F, SER465F, SER563F, SER57F, SER59F, THR11F, THR15F, THR16F, THR173D, THR25F, THR36F, THR468F, THR49F, THR4D, THR566F, THR91D, THR95D, TRP28F, TYR12F, TYR14D, TYR15D, TYR38D, TYR38F, TYR473F, TYR565F, TYR8F, VAL107F, VAL141D, VAL19D, VAL20F, VAL31F, VAL37F, VAL443F, VAL466F, VAL472F, VAL70D, VAL74D, VAL78D, VAL83D, VAL94D, VAL9F
• D-G: ALA16D, ALA16G, ALA20D, ALA35D, ALA37D, ALA41G, ALA47G, ALA85G, ARG21G, ARG23D, ARG48G, ARG49G, ASN31D, ASN86G, ASP45G, GLN32D, GLN8G, GLU18D, GLU18G, GLU26D, GLU34D, GLU46G, GLU69D, GLU7G, GLU9D, GLU9G, GLY17D, GLY17G, GLY27D, GLY50G, HIS42G, ILE36D, LEU12D, LEU12G, LEU13D, LEU13G, LEU28D, LEU30D, LEU3G, LYS10G, LYS22D, LYS24D, LYS29D, LYS2G, LYS51G, MET44G, MET71D, MET77D, PHE11G, PRO33D, PRO5G, PRO79D, PRO88G, THR4G, TYR14G, TYR15D, TYR15G, VAL19D, VAL19G, VAL70D, VAL74D, VAL78D
• D-L: ALA206D, ALA263L, ALA268L, ARG262L, ARG267L, ARG519L, ASN203D, ASN265L, ASN293L, ASN520L, ASP207D, ASP208D, ASP238L, ASP258L, ASP259L, ASP525L, CYS518L, GLN212D, GLU291L, GLY190D, GLY191D, GLY204D, GLY266L, HIS210D, ILE189D, ILE196D, ILE205D, ILE294L, LEU202D, LEU209D, LEU261L, LYS124D, LYS193D, LYS194D, LYS213D, LYS523L, LYS524L, LYS534L, MET264L, MET288L, SER192D, THR260L, THR522L, THR532L, VAL257L, VAL292L, VAL521L
• D-M: GLU216D, HIS220M
• F-G: ALA147F, ALA149F, ALA150G, ALA153G, ALA178G, ALA229F, ALA254F, ALA263F, ALA311F, ALA368F, ALA41G, ALA439F, ALA47G, ALA556F, ALA55G, ALA560F, ALA562F, ALA85G, ARG152G, ARG158G, ARG175G, ARG262F, ARG328F, ARG367F, ARG374F, ARG475F, ARG48G, ARG564F, ASN133G, ASN150F, ASN151G, ASN199G, ASN203G, ASN252F, ASN308F, ASN437F, ASN538F, ASN86G, ASN97G, ASP249F, ASP258F, ASP259F, ASP284F, ASP315F, ASP45G, ASP80G, ASP89G, CYS320F, GLN142F, GLN143F, GLN205F, GLN363F, GLN377F, GLN470F, GLN56G, GLN8G, GLU149G, GLU18G, GLU253F, GLU312F, GLU370F, GLU458F, GLU540F, GLU558F, GLU7G, GLU84G, GLU9G, GLY135G, GLY142G, GLY179G, GLY197G, GLY200G, GLY224F, GLY255F, GLY366F, GLY369F, GLY460F, GLY50G, GLY82G, GLY90G, HIS140G, HIS144G, HIS146G, HIS221G, HIS232F, HIS281F, HIS313F, HIS322F, ILE176G, ILE196G, ILE230F, ILE303F, ILE307F, ILE327F, ILE338F, ILE343F, LEU12G, LEU139G, LEU13G, LEU148F, LEU154G, LEU166G, LEU174G, LEU201G, LEU314F, LEU317F, LEU3G, LEU561F, LEU57G, LEU81G, LEU93G, LYS10G, LYS134G, LYS137G, LYS2G, LYS325F, LYS444F, LYS446F, LYS52G, LYS6G, LYS92G, MET198G, MET316F, MET318F, MET365F, MET44G, MET459F, MET58G, PHE11G, PHE144F, PHE145G, PHE147G, PHE223G, PHE440F, PHE456F, PHE542F, PHE567F, PHE568F, PHE87G, PRO136G, PRO145F, PRO227F, PRO283F, PRO301F, PRO304F, PRO373F, PRO445F, PRO471F, PRO539F, PRO555F, PRO5G, PRO79G, PRO88G, SER138G, SER143G, SER200F, SER201F, SER202F, SER228F, SER282F, SER334F, SER457F, SER563F, THR146F, THR173G, THR225F, THR226F, THR250F, THR260F, THR287F, THR300F, THR302F, THR306F, THR309F, THR319F, THR4G, THR53G, THR557F, THR566F, THR91G, THR95G, TRP98G, TYR14G, TYR15G, TYR256F, TYR305F, TYR473F, TYR474F, TYR565F, VAL141G, VAL251F, VAL257F, VAL285F, VAL310F, VAL443F, VAL472F, VAL537F, VAL54G, VAL559F, VAL83G, VAL94G, VAL96G
• F-I: ALA119I, ALA121I, ALA147F, ALA168F, ALA184F, ALA185F, ALA204F, ALA229F, ALA254F, ALA364F, ALA368F, ALA431I, ALA464I, ALA46I, ALA484I, ARG180F, ARG183F, ARG203F, ARG326F, ARG367F, ARG374F, ARG475I, ARG510F, ARG510I, ARG51I, ASN10I, ASN150F, ASN167F, ASN177F, ASN199F, ASN463I, ASN58I, ASN89I, ASP164F, ASP222F, ASP249F, ASP315F, ASP324F, ASP361F, ASP461I, ASP487I, ASP61I, ASP66I, CYS320F, GLN142F, GLN143F, GLN205F, GLN209F, GLN363F, GLN56I, GLU118I, GLU123I, GLU186F, GLU187F, GLU187I, GLU208F, GLU221F, GLU253F, GLU312F, GLU370F, GLU458I, GLU476I, GLU509F, GLU509I, GLU52I, GLU7I, GLY114I, GLY116I, GLY122I, GLY158F, GLY159F, GLY161F, GLY165F, GLY174F, GLY196F, GLY198F, GLY224F, GLY279F, GLY280F, GLY366F, GLY369F, GLY451I, GLY452I, GLY45I, GLY460I, GLY479I, GLY47I, GLY482I, GLY507F, GLY53I, GLY90I, HIS137F, HIS179F, HIS220F, HIS232F, HIS247F, HIS313F, HIS321F, HIS322F, HIS480I, HIS481I, ILE171F, ILE230F, ILE447I, ILE448I, ILE449I, ILE50I, ILE69I, ILE87I, LEU120I, LEU139F, LEU178F, LEU182F, LEU194F, LEU206F, LEU219F, LEU317F, LEU323F, LEU42I, LEU506F, LEU508F, LEU65I, LEU67I, LYS197F, LYS43I, LYS446I, LYS450I, LYS483F, LYS483I, LYS485F, LYS485I, LYS48I, LYS503F, LYS511I, LYS88I, LYS91I, MET125I, MET181F, MET316F, MET318F, MET365F, MET453I, MET459I, MET477I, MET54I, PHE138F, PHE144F, PHE217F, PHE44I, PHE456I, PHE478I, PHE486F, PHE486I, PRO141F, PRO145F, PRO162F, PRO173F, PRO227F, PRO301F, PRO373F, PRO467I, PRO469I, PRO60I, SER140F, SER200F, SER201F, SER202F, SER228F, SER360F, SER362F, SER457I, SER462I, SER465I, SER57I, SER59I, THR117I, THR11I, THR136F, THR146F, THR160F, THR166F, THR169F, THR172F, THR225F, THR226F, THR248F, THR250F, THR300F, THR319F, THR468I, THR488I, THR49I, THR64I, THR70I, TRP176F, TRP223F, TYR188F, TYR473I, TYR474I, VAL112I, VAL113I, VAL115I, VAL163F, VAL175F, VAL192F, VAL207F, VAL251F, VAL371F, VAL435I, VAL454I, VAL455I, VAL466I, VAL472I, VAL68I
• F-J: ALA206J, ALA263F, ALA268F, ARG262F, ARG267F, ARG519F, ASN203J, ASN265F, ASN293F, ASN520F, ASP207J, ASP208J, ASP238F, ASP258F, ASP259F, ASP525F, CYS518F, GLN212J, GLU291F, GLY190J, GLY191J, GLY204J, GLY266F, HIS210J, ILE189J, ILE196J, ILE205J, ILE294F, LEU202J, LEU209J, LEU261F, LEU295F, LYS124J, LYS193J, LYS194J, LYS213J, LYS523F, LYS524F, LYS534F, MET264F, MET288F, SER192J, THR260F, THR522F, THR532F, VAL257F, VAL292F, VAL521F
• F-L: ARG519F, ARG519L, ASN100F, ASN100L, ASN517F, ASN517L, ASN520F, ASN520L, ASN58F, ASN58L, ASN63F, ASN63L, ASP102F, ASP102L, ASP105F, ASP105L, ASP238F, ASP238L, ASP241F, ASP241L, ASP525F, ASP525L, ASP61F, ASP61L, CYS518F, CYS518L, GLN104F, GLN104L, GLU239F, GLU239L, GLU420F, GLU420L, GLU499F, GLU499L, GLU62F, GLU62L, GLY106F, GLY106L, HIS110F, HIS110L, HIS93F, HIS93L, ILE414F, ILE414L, LYS101F, LYS101L, LYS495F, LYS495L, LYS516F, LYS516L, LYS524F, LYS524L, LYS527F, LYS527L, MET103F, MET103L, PRO109F, PRO109L, PRO514F, PRO514L, PRO60F, PRO60L, SER419L, SER57F, SER57L, SER59F, SER59L, THR522F, THR522L, THR64F, THR64L, TYR421F, TYR421L, TYR77F, TYR77L, VAL112F, VAL112L, VAL515F, VAL515L, VAL521F, VAL521L
• F-R: ALA204R, ARG203F, ARG203R, ASP238F, GLU239F
• G-I: ALA107G, ALA113G, ALA122G, ALA16G, ALA206G, ALA20G, ALA29I, ALA35G, ALA37G, ALA41G, ALA439I, ALA464I, ALA46I, ALA560I, ALA562I, ALA85G, ARG165G, ARG21G, ARG21I, ARG23G, ARG475I, ARG51I, ARG564I, ARG5I, ASN100I, ASN10I, ASN121G, ASN172G, ASN199G, ASN203G, ASN31G, ASN437I, ASN463I, ASN58I, ASN71I, ASN76G, ASN86G, ASP102I, ASP103G, ASP104G, ASP105I, ASP115G, ASP117G, ASP167G, ASP18I, ASP24I, ASP26I, ASP34I, ASP395I, ASP461I, ASP80G, GLN104I, GLN32G, GLN470I, GLN56I, GLN6I, GLN8G, GLU109G, GLU119G, GLU123I, GLU149G, GLU18G, GLU30I, GLU34G, GLU40I, GLU41I, GLU458I, GLU52I, GLU7G, GLU7I, GLU84G, GLU9G, GLY106I, GLY108G, GLY123G, GLY124I, GLY13I, GLY142G, GLY163G, GLY171G, GLY17G, GLY17I, GLY190G, GLY191G, GLY197G, GLY200G, GLY204G, GLY23I, GLY39I, GLY45I, GLY460I, GLY47I, GLY53I, GLY55I, GLY73G, GLY75G, GLY82G, HIS140G, HIS144G, HIS146G, HIS185G, ILE110G, ILE118G, ILE126G, ILE126I, ILE168G, ILE187G, ILE189G, ILE195G, ILE196G, ILE205G, ILE36G, ILE39G, ILE43G, ILE50I, LEU120G, LEU12G, LEU13G, LEU166G, LEU174G, LEU202G, LEU22I, LEU27I, LEU30G, LEU42I, LEU561I, LEU73I, LEU81G, LEU93G, LYS101I, LYS106G, LYS10G, LYS111G, LYS116G, LYS124G, LYS164G, LYS193G, LYS194G, LYS19I, LYS22G, LYS29G, LYS2I, LYS384I, LYS43I, LYS444I, LYS48I, LYS4I, LYS6G, LYS82I, LYS92G, LYS97I, MET103I, MET125I, MET198G, MET1I, MET3I, MET44G, MET459I, MET54I, MET71G, MET77G, PHE105G, PHE112G, PHE11G, PHE145G, PHE147G, PHE440I, PHE441I, PHE44I, PHE567I, PHE568I, PRO14I, PRO169G, PRO188G, PRO33G, PRO438I, PRO469I, PRO471I, PRO5G, PRO60I, PRO72G, PRO79G, SER114G, SER143G, SER170G, SER192G, SER40G, SER462I, SER465I, SER563I, SER57I, SER59I, THR11I, THR15I, THR16I, THR173G, THR25I, THR36I, THR468I, THR49I, THR4G, THR566I, THR91G, THR95G, TRP28I, TYR12I, TYR14G, TYR15G, TYR38G, TYR38I, TYR473I, TYR565I, TYR8I, VAL107I, VAL141G, VAL19G, VAL20I, VAL31I, VAL37I, VAL443I, VAL466I, VAL472I, VAL70G, VAL74G, VAL78G, VAL83G, VAL94G, VAL9I
• G-J: GLU216J, HIS220G
• J-L: ALA107J, ALA113J, ALA122J, ALA16J, ALA206J, ALA20J, ALA29L, ALA35J, ALA37J, ALA41J, ALA439L, ALA464L, ALA46L, ALA560L, ALA562L, ALA85J, ARG165J, ARG21J, ARG21L, ARG23J, ARG388L, ARG475L, ARG51L, ARG564L, ARG5L, ASN100L, ASN10L, ASN121J, ASN172J, ASN199J, ASN203J, ASN31J, ASN437L, ASN463L, ASN58L, ASN71L, ASN76J, ASN86J, ASP102L, ASP103J, ASP104J, ASP105L, ASP115J, ASP117J, ASP167J, ASP18L, ASP24L, ASP26L, ASP34L, ASP395L, ASP461L, ASP80J, GLN104L, GLN32J, GLN470L, GLN56L, GLN6L, GLN8J, GLU109J, GLU119J, GLU123L, GLU149J, GLU18J, GLU30L, GLU34J, GLU40L, GLU41L, GLU458L, GLU52L, GLU7J, GLU7L, GLU84J, GLU9J, GLY106L, GLY108J, GLY123J, GLY124L, GLY13L, GLY142J, GLY163J, GLY171J, GLY17J, GLY17L, GLY190J, GLY191J, GLY197J, GLY200J, GLY204J, GLY23L, GLY39L, GLY45L, GLY460L, GLY47L, GLY53L, GLY55L, GLY73J, GLY75J, GLY82J, HIS140J, HIS144J, HIS146J, HIS185J, ILE110J, ILE118J, ILE126J, ILE126L, ILE168J, ILE187J, ILE189J, ILE195J, ILE196J, ILE205J, ILE36J, ILE39J, ILE43J, ILE50L, LEU120J, LEU12J, LEU13J, LEU166J, LEU174J, LEU202J, LEU22L, LEU27L, LEU30J, LEU42L, LEU561L, LEU73L, LEU81J, LEU93J, LYS101L, LYS106J, LYS10J, LYS111J, LYS116J, LYS124J, LYS164J, LYS193J, LYS194J, LYS19L, LYS22J, LYS29J, LYS2L, LYS384L, LYS43L, LYS444L, LYS48L, LYS4L, LYS6J, LYS82L, LYS92J, LYS97L, MET103L, MET125L, MET198J, MET1L, MET3L, MET44J, MET459L, MET54L, MET71J, MET77J, PHE105J, PHE112J, PHE11J, PHE145J, PHE147J, PHE440L, PHE441L, PHE44L, PHE567L, PHE568L, PRO14L, PRO169J, PRO188J, PRO33J, PRO438L, PRO469L, PRO471L, PRO5J, PRO60L, PRO72J, PRO79J, SER114J, SER143J, SER170J, SER192J, SER40J, SER462L, SER465L, SER563L, SER57L, SER59L, THR11L, THR15L, THR16L, THR173J, THR25L, THR36L, THR468L, THR49L, THR4J, THR566L, THR91J, THR95J, TRP28L, TYR12L, TYR14J, TYR15J, TYR38J, TYR38L, TYR473L, TYR565L, TYR8L, VAL107L, VAL141J, VAL19J, VAL20L, VAL31L, VAL37L, VAL443L, VAL466L, VAL472L, VAL70J, VAL74J, VAL78J, VAL83J, VAL94J, VAL9L
• J-M: ALA16J, ALA16M, ALA20J, ALA35J, ALA37J, ALA41M, ALA47M, ALA85M, ARG21M, ARG23J, ARG48M, ARG49M, ASN31J, ASN86M, ASP45M, GLN32J, GLN8M, GLU18J, GLU18M, GLU26J, GLU34J, GLU46M, GLU69J, GLU7M, GLU9J, GLU9M, GLY17J, GLY17M, GLY27J, GLY50M, HIS42M, ILE36J, LEU12J, LEU12M, LEU13J, LEU13M, LEU28J, LEU30J, LEU3M, LYS10M, LYS22J, LYS24J, LYS29J, LYS2M, LYS51M, MET44M, MET71J, MET77J, PHE11M, PRO33J, PRO5M, PRO79J, PRO88M, THR4M, TYR14M, TYR15J, TYR15M, VAL19J, VAL19M, VAL70J, VAL74J, VAL78J
• J-P: ALA16J, ALA16P, ALA20P, ALA35P, ALA37P, ALA41J, ALA47J, ALA85J, ARG21J, ARG23P, ARG48J, ARG49J, ASN31P, ASN86J, ASP45J, GLN32P, GLN8J, GLU18J, GLU18P, GLU26P, GLU34P, GLU46J, GLU69P, GLU7J, GLU9J, GLU9P, GLY17J, GLY17P, GLY27P, GLY50J, HIS42J, ILE36P, LEU12J, LEU12P, LEU13J, LEU13P, LEU28P, LEU30P, LEU3J, LYS10J, LYS22P, LYS24P, LYS29P, LYS2J, LYS51J, MET44J, MET71P, MET77P, PHE11J, PRO33P, PRO5J, PRO79P, PRO88J, THR4J, TYR14J, TYR15J, TYR15P, VAL19J, VAL19P, VAL70P, VAL74P, VAL78P
• J-R: ALA147R, ALA149R, ALA150J, ALA153J, ALA178J, ALA229R, ALA254R, ALA263R, ALA311R, ALA368R, ALA41J, ALA439R, ALA47J, ALA556R, ALA55J, ALA560R, ALA562R, ALA85J, ARG152J, ARG158J, ARG175J, ARG262R, ARG328R, ARG367R, ARG374R, ARG475R, ARG48J, ARG564R, ASN133J, ASN150R, ASN151J, ASN172J, ASN199J, ASN203J, ASN252R, ASN308R, ASN437R, ASN86J, ASN97J, ASP249R, ASP258R, ASP259R, ASP284R, ASP315R, ASP45J, ASP80J, ASP89J, CYS320R, GLN142R, GLN143R, GLN205R, GLN363R, GLN377R, GLN470R, GLN56J, GLN8J, GLU149J, GLU18J, GLU253R, GLU312R, GLU370R, GLU458R, GLU540R, GLU558R, GLU7J, GLU84J, GLU9J, GLY135J, GLY142J, GLY177J, GLY179J, GLY197J, GLY200J, GLY224R, GLY255R, GLY366R, GLY369R, GLY460R, GLY50J, GLY82J, GLY90J, HIS140J, HIS144J, HIS146J, HIS221J, HIS232R, HIS281R, HIS313R, HIS322R, ILE176J, ILE196J, ILE230R, ILE303R, ILE307R, ILE327R, ILE338R, ILE343R, LEU12J, LEU139J, LEU13J, LEU148R, LEU154J, LEU166J, LEU174J, LEU201J, LEU314R, LEU317R, LEU3J, LEU561R, LEU57J, LEU81J, LEU93J, LYS10J, LYS134J, LYS137J, LYS217J, LYS2J, LYS325R, LYS444R, LYS446R, LYS52J, LYS6J, LYS92J, MET198J, MET316R, MET318R, MET365R, MET44J, MET459R, MET58J, PHE11J, PHE144R, PHE145J, PHE147J, PHE223J, PHE440R, PHE456R, PHE542R, PHE567R, PHE568R, PHE87J, PRO136J, PRO145R, PRO227R, PRO283R, PRO301R, PRO304R, PRO373R, PRO445R, PRO471R, PRO539R, PRO555R, PRO5J, PRO79J, PRO88J, SER138J, SER143J, SER200R, SER201R, SER202R, SER228R, SER282R, SER334R, SER457R, SER563R, THR146R, THR173J, THR225R, THR226R, THR250R, THR260R, THR287R, THR300R, THR302R, THR306R, THR309R, THR319R, THR4J, THR53J, THR557R, THR566R, THR91J, THR95J, TRP98J, TYR14J, TYR15J, TYR256R, TYR305R, TYR473R, TYR474R, TYR565R, VAL141J, VAL251R, VAL257R, VAL285R, VAL310R, VAL443R, VAL472R, VAL537R, VAL54J, VAL559R, VAL83J, VAL94J, VAL96J
• L-M: ALA147L, ALA149L, ALA150M, ALA153M, ALA178M, ALA229L, ALA254L, ALA263L, ALA311L, ALA368L, ALA41M, ALA439L, ALA47M, ALA556L, ALA55M, ALA560L, ALA562L, ALA85M, ARG152M, ARG158M, ARG175M, ARG262L, ARG328L, ARG367L, ARG374L, ARG475L, ARG48M, ARG564L, ASN133M, ASN150L, ASN151M, ASN199M, ASN203M, ASN252L, ASN308L, ASN437L, ASN538L, ASN86M, ASN97M, ASP231L, ASP249L, ASP258L, ASP259L, ASP284L, ASP315L, ASP45M, ASP80M, ASP89M, CYS320L, GLN142L, GLN143L, GLN205L, GLN363L, GLN377L, GLN470L, GLN56M, GLN8M, GLU149M, GLU18M, GLU253L, GLU312L, GLU370L, GLU458L, GLU540L, GLU558L, GLU7M, GLU84M, GLU9M, GLY135M, GLY142M, GLY177M, GLY179M, GLY197M, GLY200M, GLY224L, GLY255L, GLY366L, GLY369L, GLY460L, GLY50M, GLY82M, GLY90M, HIS140M, HIS144M, HIS146M, HIS221M, HIS232L, HIS281L, HIS313L, HIS322L, ILE176M, ILE196M, ILE230L, ILE303L, ILE307L, ILE327L, ILE338L, ILE343L, LEU12M, LEU139M, LEU13M, LEU148L, LEU154M, LEU166M, LEU174M, LEU201M, LEU314L, LEU317L, LEU3M, LEU561L, LEU57M, LEU81M, LEU93M, LYS10M, LYS134M, LYS137M, LYS2M, LYS325L, LYS444L, LYS446L, LYS52M, LYS6M, LYS92M, MET198M, MET316L, MET318L, MET365L, MET44M, MET459L, MET58M, PHE11M, PHE144L, PHE145M, PHE147M, PHE223M, PHE440L, PHE456L, PHE542L, PHE567L, PHE568L, PHE87M, PRO136M, PRO145L, PRO227L, PRO283L, PRO301L, PRO304L, PRO373L, PRO445L, PRO471L, PRO539L, PRO555L, PRO5M, PRO79M, PRO88M, SER138M, SER143M, SER200L, SER201L, SER202L, SER228L, SER282L, SER334L, SER457L, SER563L, THR146L, THR173M, THR225L, THR226L, THR250L, THR260L, THR287L, THR300L, THR302L, THR306L, THR309L, THR319L, THR4M, THR53M, THR557L, THR566L, THR91M, THR95M, TRP98M, TYR14M, TYR15M, TYR256L, TYR305L, TYR473L, TYR474L, TYR565L, VAL141M, VAL251L, VAL257L, VAL285L, VAL310L, VAL443L, VAL472L, VAL537L, VAL54M, VAL559L, VAL83M, VAL94M, VAL96M
• L-O: ALA119O, ALA121O, ALA147L, ALA168L, ALA184L, ALA185L, ALA204L, ALA229L, ALA254L, ALA364L, ALA368L, ALA431O, ALA464O, ALA46O, ALA484O, ARG180L, ARG183L, ARG203L, ARG326L, ARG367L, ARG374L, ARG475O, ARG510L, ARG510O, ARG51O, ASN10O, ASN150L, ASN167L, ASN177L, ASN199L, ASN463O, ASN58O, ASN89O, ASP164L, ASP222L, ASP249L, ASP315L, ASP324L, ASP361L, ASP461O, ASP487O, ASP61O, ASP66O, CYS320L, GLN142L, GLN143L, GLN205L, GLN209L, GLN363L, GLN56O, GLU118O, GLU123O, GLU186L, GLU187L, GLU187O, GLU208L, GLU221L, GLU253L, GLU312L, GLU370L, GLU458O, GLU476O, GLU509L, GLU509O, GLU52O, GLU7O, GLY114O, GLY116O, GLY122O, GLY158L, GLY159L, GLY161L, GLY165L, GLY174L, GLY196L, GLY198L, GLY224L, GLY279L, GLY280L, GLY366L, GLY369L, GLY451O, GLY452O, GLY45O, GLY460O, GLY479O, GLY47O, GLY482O, GLY507L, GLY53O, GLY90O, HIS137L, HIS179L, HIS220L, HIS232L, HIS247L, HIS313L, HIS321L, HIS322L, HIS480O, HIS481O, ILE171L, ILE230L, ILE447O, ILE448O, ILE449O, ILE50O, ILE69O, ILE87O, LEU120O, LEU139L, LEU178L, LEU182L, LEU194L, LEU206L, LEU219L, LEU317L, LEU323L, LEU42O, LEU506L, LEU508L, LEU65O, LEU67O, LYS197L, LYS43O, LYS446O, LYS450O, LYS483L, LYS483O, LYS485L, LYS485O, LYS48O, LYS503L, LYS511O, LYS88O, LYS91O, MET125O, MET181L, MET316L, MET318L, MET365L, MET453O, MET459O, MET477O, MET54O, PHE138L, PHE144L, PHE217L, PHE44O, PHE456O, PHE478O, PHE486L, PHE486O, PHE568L, PRO141L, PRO145L, PRO162L, PRO173L, PRO227L, PRO301L, PRO373L, PRO467O, PRO469O, PRO60O, SER140L, SER200L, SER201L, SER202L, SER228L, SER360L, SER362L, SER457O, SER462O, SER465O, SER57O, SER59O, THR117O, THR11O, THR136L, THR146L, THR160L, THR166L, THR169L, THR172L, THR225L, THR226L, THR248L, THR250L, THR300L, THR319L, THR468O, THR488O, THR49O, THR64O, THR70O, TRP176L, TRP223L, TYR188L, TYR473O, TYR474O, VAL112O, VAL113O, VAL115O, VAL163L, VAL175L, VAL192L, VAL207L, VAL251L, VAL371L, VAL435O, VAL454O, VAL455O, VAL466O, VAL472O, VAL68O
• L-R: ALA119L, ALA121L, ALA147R, ALA168R, ALA184R, ALA185R, ALA204R, ALA229R, ALA254R, ALA364R, ALA368R, ALA431L, ALA464L, ALA46L, ALA484L, ARG180R, ARG183R, ARG203R, ARG326R, ARG367R, ARG374R, ARG475L, ARG510L, ARG510R, ARG51L, ASN10L, ASN150R, ASN167R, ASN177R, ASN199R, ASN463L, ASN58L, ASN89L, ASP164R, ASP222R, ASP249R, ASP315R, ASP324R, ASP361R, ASP461L, ASP487L, ASP61L, ASP66L, CYS320R, GLN142R, GLN143R, GLN205R, GLN209R, GLN363R, GLN56L, GLU118L, GLU123L, GLU186R, GLU187L, GLU187R, GLU208R, GLU221R, GLU253R, GLU312R, GLU370R, GLU458L, GLU476L, GLU509L, GLU509R, GLU52L, GLU7L, GLY114L, GLY116L, GLY122L, GLY158R, GLY159R, GLY161R, GLY165R, GLY174R, GLY196R, GLY198R, GLY224R, GLY279R, GLY366R, GLY369R, GLY451L, GLY452L, GLY45L, GLY460L, GLY479L, GLY47L, GLY482L, GLY507R, GLY53L, GLY90L, HIS137R, HIS179R, HIS220R, HIS232R, HIS247R, HIS313R, HIS321R, HIS322R, HIS480L, HIS481L, ILE171R, ILE230R, ILE447L, ILE448L, ILE449L, ILE50L, ILE69L, ILE87L, LEU120L, LEU139R, LEU178R, LEU182R, LEU194R, LEU206R, LEU219R, LEU317R, LEU323R, LEU42L, LEU506R, LEU508R, LEU65L, LEU67L, LYS197R, LYS43L, LYS446L, LYS450L, LYS483L, LYS483R, LYS485L, LYS485R, LYS48L, LYS503R, LYS511L, LYS88L, LYS91L, MET125L, MET181R, MET190R, MET316R, MET318R, MET365R, MET453L, MET459L, MET477L, MET54L, PHE138R, PHE144R, PHE217R, PHE44L, PHE456L, PHE478L, PHE486L, PHE486R, PHE568R, PRO141R, PRO145R, PRO162R, PRO173R, PRO227R, PRO301R, PRO373R, PRO467L, PRO469L, PRO60L, SER140R, SER200R, SER201R, SER202R, SER228R, SER360R, SER362R, SER457L, SER462L, SER465L, SER57L, SER59L, THR117L, THR11L, THR136R, THR146R, THR160R, THR166R, THR169R, THR172R, THR225R, THR226R, THR248R, THR250R, THR299R, THR300R, THR319R, THR468L, THR488L, THR49L, THR64L, THR70L, TRP176R, TRP223R, TYR188R, TYR473L, TYR474L, VAL112L, VAL113L, VAL115L, VAL163R, VAL175R, VAL192R, VAL207R, VAL251R, VAL371R, VAL435L, VAL454L, VAL455L, VAL466L, VAL472L, VAL68L
• M-O: ALA107M, ALA113M, ALA122M, ALA16M, ALA206M, ALA20M, ALA29O, ALA35M, ALA37M, ALA41M, ALA439O, ALA464O, ALA46O, ALA560O, ALA562O, ALA85M, ARG165M, ARG21M, ARG21O, ARG23M, ARG388O, ARG475O, ARG51O, ARG564O, ARG5O, ASN100O, ASN10O, ASN121M, ASN172M, ASN199M, ASN203M, ASN31M, ASN437O, ASN463O, ASN58O, ASN71O, ASN76M, ASN86M, ASP102O, ASP103M, ASP104M, ASP105O, ASP115M, ASP117M, ASP167M, ASP18O, ASP24O, ASP26O, ASP34O, ASP395O, ASP461O, ASP80M, GLN104O, GLN32M, GLN470O, GLN56O, GLN6O, GLN8M, GLU109M, GLU119M, GLU123O, GLU149M, GLU18M, GLU30O, GLU34M, GLU40O, GLU41O, GLU458O, GLU52O, GLU7M, GLU7O, GLU84M, GLU9M, GLY106O, GLY108M, GLY123M, GLY124O, GLY13O, GLY142M, GLY163M, GLY171M, GLY17M, GLY17O, GLY190M, GLY191M, GLY197M, GLY200M, GLY204M, GLY23O, GLY39O, GLY45O, GLY460O, GLY47O, GLY53O, GLY55O, GLY73M, GLY75M, GLY82M, HIS140M, HIS144M, HIS146M, HIS185M, ILE110M, ILE118M, ILE126M, ILE126O, ILE168M, ILE187M, ILE189M, ILE195M, ILE196M, ILE205M, ILE36M, ILE39M, ILE43M, ILE50O, LEU120M, LEU12M, LEU13M, LEU166M, LEU174M, LEU202M, LEU22O, LEU27O, LEU30M, LEU42O, LEU561O, LEU73O, LEU81M, LEU93M, LYS101O, LYS106M, LYS10M, LYS111M, LYS116M, LYS124M, LYS164M, LYS193M, LYS194M, LYS19O, LYS22M, LYS29M, LYS2O, LYS384O, LYS43O, LYS444O, LYS48O, LYS4O, LYS6M, LYS82O, LYS92M, LYS97O, MET103O, MET125O, MET198M, MET1O, MET3O, MET44M, MET459O, MET54O, MET71M, MET77M, PHE105M, PHE112M, PHE11M, PHE145M, PHE147M, PHE440O, PHE441O, PHE44O, PHE567O, PHE568O, PRO14O, PRO169M, PRO188M, PRO33M, PRO438O, PRO469O, PRO471O, PRO5M, PRO60O, PRO72M, PRO79M, SER114M, SER143M, SER170M, SER192M, SER40M, SER462O, SER465O, SER563O, SER57O, SER59O, THR11O, THR15O, THR16O, THR173M, THR25O, THR36O, THR468O, THR49O, THR4M, THR566O, THR91M, THR95M, TRP28O, TYR12O, TYR14M, TYR15M, TYR38M, TYR38O, TYR473O, TYR565O, TYR8O, VAL107O, VAL141M, VAL19M, VAL20O, VAL31O, VAL37O, VAL443O, VAL466O, VAL472O, VAL70M, VAL74M, VAL78M, VAL83M, VAL94M, VAL9O
• M-P: ALA16M, ALA16P, ALA20M, ALA35M, ALA37M, ALA41P, ALA47P, ALA85P, ARG21P, ARG23M, ARG48P, ARG49P, ASN31M, ASN86P, ASP45P, GLN32M, GLN8P, GLU18M, GLU18P, GLU26M, GLU34M, GLU46P, GLU69M, GLU7P, GLU9M, GLU9P, GLY17M, GLY17P, GLY27M, GLY50P, HIS42P, ILE36M, LEU12M, LEU12P, LEU13M, LEU13P, LEU28M, LEU30M, LEU3P, LYS10P, LYS22M, LYS24M, LYS29M, LYS2P, LYS51P, MET44P, MET71M, MET77M, PHE11P, PRO33M, PRO79M, PRO88P, THR4P, TYR14P, TYR15M, TYR15P, VAL19M, VAL19P, VAL70M, VAL74M, VAL78M
• O-P: ALA147O, ALA149O, ALA150P, ALA153P, ALA178P, ALA229O, ALA254O, ALA263O, ALA311O, ALA368O, ALA41P, ALA439O, ALA47P, ALA556O, ALA55P, ALA560O, ALA562O, ALA85P, ARG152P, ARG158P, ARG175P, ARG262O, ARG328O, ARG367O, ARG374O, ARG475O, ARG48P, ARG564O, ASN133P, ASN150O, ASN151P, ASN172P, ASN199P, ASN203P, ASN252O, ASN308O, ASN437O, ASN86P, ASN97P, ASP231O, ASP249O, ASP258O, ASP259O, ASP284O, ASP315O, ASP45P, ASP80P, ASP89P, CYS320O, GLN142O, GLN143O, GLN205O, GLN363O, GLN377O, GLN470O, GLN56P, GLN8P, GLU149P, GLU18P, GLU253O, GLU312O, GLU370O, GLU458O, GLU540O, GLU558O, GLU7P, GLU84P, GLU9P, GLY135P, GLY142P, GLY179P, GLY197P, GLY200P, GLY224O, GLY255O, GLY366O, GLY369O, GLY460O, GLY50P, GLY82P, GLY90P, HIS140P, HIS144P, HIS146P, HIS221P, HIS232O, HIS281O, HIS313O, HIS322O, ILE176P, ILE196P, ILE230O, ILE303O, ILE307O, ILE327O, ILE338O, ILE343O, LEU12P, LEU139P, LEU13P, LEU148O, LEU154P, LEU166P, LEU174P, LEU201P, LEU314O, LEU317O, LEU323O, LEU3P, LEU561O, LEU57P, LEU81P, LEU93P, LYS10P, LYS134P, LYS137P, LYS2P, LYS325O, LYS444O, LYS446O, LYS52P, LYS6P, LYS92P, MET198P, MET316O, MET318O, MET365O, MET44P, MET459O, MET58P, PHE11P, PHE144O, PHE145P, PHE147P, PHE223P, PHE440O, PHE456O, PHE542O, PHE567O, PHE568O, PHE87P, PRO136P, PRO145O, PRO227O, PRO283O, PRO301O, PRO304O, PRO373O, PRO445O, PRO471O, PRO539O, PRO555O, PRO5P, PRO79P, PRO88P, SER138P, SER140O, SER143P, SER200O, SER201O, SER202O, SER228O, SER282O, SER334O, SER457O, SER563O, THR146O, THR173P, THR225O, THR226O, THR250O, THR260O, THR287O, THR300O, THR302O, THR306O, THR309O, THR319O, THR4P, THR53P, THR557O, THR566O, THR91P, THR95P, TRP98P, TYR14P, TYR15P, TYR256O, TYR305O, TYR473O, TYR474O, TYR565O, VAL141P, VAL251O, VAL257O, VAL285O, VAL310O, VAL443O, VAL472O, VAL537O, VAL54P, VAL559O, VAL83P, VAL94P, VAL96P
• O-R: ALA119R, ALA121R, ALA147O, ALA168O, ALA184O, ALA185O, ALA204O, ALA229O, ALA254O, ALA364O, ALA368O, ALA431R, ALA464R, ALA46R, ALA484R, ARG180O, ARG183O, ARG203O, ARG326O, ARG367O, ARG374O, ARG475R, ARG510O, ARG510R, ARG51R, ASN10R, ASN150O, ASN167O, ASN177O, ASN199O, ASN463R, ASN58R, ASN89R, ASP164O, ASP222O, ASP249O, ASP315O, ASP324O, ASP361O, ASP461R, ASP487R, ASP61R, ASP66R, CYS320O, GLN142O, GLN143O, GLN205O, GLN209O, GLN363O, GLN56R, GLU118R, GLU123R, GLU186O, GLU187O, GLU187R, GLU208O, GLU221O, GLU253O, GLU312O, GLU370O, GLU458R, GLU476R, GLU509O, GLU509R, GLU52R, GLU7R, GLY114R, GLY116R, GLY122R, GLY158O, GLY159O, GLY161O, GLY165O, GLY174O, GLY196O, GLY198O, GLY224O, GLY279O, GLY280O, GLY366O, GLY369O, GLY451R, GLY452R, GLY45R, GLY460R, GLY479R, GLY47R, GLY482R, GLY507O, GLY53R, GLY90R, HIS137O, HIS179O, HIS220O, HIS232O, HIS247O, HIS313O, HIS321O, HIS322O, HIS480R, HIS481R, ILE171O, ILE230O, ILE447R, ILE448R, ILE449R, ILE50R, ILE69R, ILE87R, LEU120R, LEU139O, LEU178O, LEU182O, LEU194O, LEU206O, LEU219O, LEU317O, LEU323O, LEU42R, LEU506O, LEU508O, LEU65R, LEU67R, LYS197O, LYS43R, LYS446R, LYS450R, LYS483O, LYS483R, LYS485O, LYS485R, LYS48R, LYS511R, LYS88R, LYS91R, MET125R, MET181O, MET316O, MET318O, MET365O, MET453R, MET459R, MET477R, MET54R, PHE138O, PHE144O, PHE217O, PHE44R, PHE456R, PHE478R, PHE486O, PHE486R, PRO141O, PRO145O, PRO162O, PRO173O, PRO227O, PRO301O, PRO373O, PRO467R, PRO469R, PRO60R, SER140O, SER200O, SER201O, SER202O, SER228O, SER360O, SER362O, SER457R, SER462R, SER465R, SER57R, SER59R, THR117R, THR11R, THR136O, THR146O, THR160O, THR166O, THR169O, THR172O, THR225O, THR226O, THR248O, THR250O, THR300O, THR319O, THR468R, THR488R, THR49R, THR64R, THR70R, TRP176O, TRP223O, TYR188O, TYR473R, TYR474R, VAL112R, VAL113R, VAL115R, VAL163O, VAL175O, VAL192O, VAL207O, VAL251O, VAL371O, VAL435R, VAL454R, VAL455R, VAL466R, VAL472R, VAL68R
• P-R: ALA107P, ALA113P, ALA122P, ALA16P, ALA206P, ALA20P, ALA29R, ALA35P, ALA37P, ALA41P, ALA439R, ALA464R, ALA46R, ALA560R, ALA562R, ALA85P, ARG165P, ARG21P, ARG21R, ARG23P, ARG388R, ARG475R, ARG51R, ARG564R, ARG5R, ASN100R, ASN10R, ASN121P, ASN172P, ASN199P, ASN203P, ASN31P, ASN437R, ASN463R, ASN58R, ASN71R, ASN76P, ASN86P, ASP102R, ASP103P, ASP104P, ASP105R, ASP115P, ASP117P, ASP167P, ASP18R, ASP24R, ASP26R, ASP34R, ASP395R, ASP461R, ASP80P, GLN104R, GLN32P, GLN470R, GLN56R, GLN6R, GLN8P, GLU109P, GLU119P, GLU123R, GLU149P, GLU18P, GLU30R, GLU34P, GLU40R, GLU41R, GLU458R, GLU52R, GLU7P, GLU7R, GLU84P, GLU9P, GLY106R, GLY108P, GLY123P, GLY124R, GLY13R, GLY142P, GLY163P, GLY171P, GLY17P, GLY17R, GLY190P, GLY191P, GLY197P, GLY200P, GLY204P, GLY23R, GLY39R, GLY45R, GLY460R, GLY47R, GLY53R, GLY55R, GLY73P, GLY75P, GLY82P, HIS140P, HIS144P, HIS146P, HIS185P, ILE110P, ILE118P, ILE126P, ILE126R, ILE168P, ILE187P, ILE189P, ILE195P, ILE196P, ILE205P, ILE36P, ILE39P, ILE43P, ILE50R, LEU120P, LEU12P, LEU13P, LEU166P, LEU174P, LEU202P, LEU22R, LEU27R, LEU30P, LEU42R, LEU561R, LEU73R, LEU81P, LEU93P, LYS101R, LYS106P, LYS10P, LYS111P, LYS116P, LYS124P, LYS164P, LYS193P, LYS194P, LYS19R, LYS22P, LYS29P, LYS2R, LYS384R, LYS43R, LYS444R, LYS48R, LYS4R, LYS6P, LYS82R, LYS92P, LYS97R, MET103R, MET125R, MET198P, MET1R, MET3R, MET44P, MET459R, MET54R, MET71P, MET77P, PHE105P, PHE112P, PHE11P, PHE145P, PHE147P, PHE440R, PHE441R, PHE44R, PHE567R, PHE568R, PRO14R, PRO169P, PRO188P, PRO33P, PRO438R, PRO469R, PRO471R, PRO5P, PRO60R, PRO72P, PRO79P, SER114P, SER143P, SER170P, SER192P, SER40P, SER462R, SER465R, SER563R, SER57R, SER59R, THR11R, THR15R, THR16R, THR173P, THR25R, THR36R, THR468R, THR49R, THR4P, THR566R, THR91P, THR95P, TRP28R, TYR12R, TYR14P, TYR15P, TYR38P, TYR38R, TYR473R, TYR565R, TYR8R, VAL107R, VAL141P, VAL19P, VAL20R, VAL31R, VAL37R, VAL443R, VAL466R, VAL472R, VAL70P, VAL74P, VAL78P, VAL83P, VAL94P, VAL9R