3QG5

the mre11:rad50 complex forms an atp dependent molecular clamp in dna double-strand break repair

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 185
  • Norm. En. per Res.: -3.0274
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-23.2112	-67.3155	-361.986	-452.5127	194	80	21	22167	8	113	103
B-D	-54.5755	-27.6502	-477.84	-560.0657	185	89	19	22913	3	104	99
C-D	0.0	1.5195	-113.442	-111.9225	70	14	10	7116	0	8	7

Interface residues

• A-C: ALA284C, ALA385C, ALA725A, ALA732A, ALA784A, ALA787A, ALA812A, ARG132A, ARG289C, ARG293C, ARG2A, ARG328C, ARG336C, ARG362C, ARG705A, ARG716A, ARG721A, ARG729A, ARG741A, ARG762A, ARG78A, ARG790A, ARG820A, ASN294C, ASN365C, ASN699A, ASN700A, ASN713A, ASN739A, ASN822A, ASP162A, ASP281C, ASP290C, ASP306C, ASP347C, ASP350C, ASP374C, ASP378C, ASP696A, ASP702A, ASP710A, ASP735A, ASP757A, ASP792A, CYS292C, GLN165A, GLU130A, GLU168A, GLU171A, GLU174A, GLU304C, GLU305C, GLU332C, GLU333C, GLU337C, GLU340C, GLU341C, GLU344C, GLU345C, GLU353C, GLU357C, GLU363C, GLU375C, GLU379C, GLU384C, GLU697A, GLU761A, GLU771A, GLU785A, GLU809A, GLU817A, GLU819A, GLY128A, GLY720A, GLY740A, GLY759A, GLY766A, GLY769A, GLY770A, GLY789A, GLY79A, HIS366C, ILE129A, ILE160A, ILE280C, ILE288C, ILE331C, ILE372C, ILE736A, ILE760A, ILE811A, LEU127A, LEU170A, LEU173A, LEU176A, LEU177A, LEU275C, LEU285C, LEU335C, LEU346C, LEU349C, LEU354C, LEU359C, LEU369C, LEU370C, LEU373C, LEU376C, LEU377C, LEU701A, LEU703A, LEU704A, LEU708A, LEU734A, LEU737A, LEU767A, LEU774A, LEU783A, LEU791A, LEU815A, LEU818A, LEU821A, LYS167A, LYS172A, LYS175A, LYS178A, LYS180A, LYS273C, LYS278C, LYS279C, LYS286C, LYS343C, LYS348C, LYS356C, LYS361C, LYS368C, LYS371C, LYS381C, LYS706A, LYS711A, LYS728A, LYS731A, LYS810A, LYS816A, LYS823A, PHE164A, PHE291C, PHE295C, PHE342C, PHE352C, PHE355C, PHE709A, PHE714A, PHE718A, PHE742A, PRO339C, PRO763A, SER161A, SER166A, SER283C, SER287C, SER307C, SER338C, SER383C, SER712A, SER715A, SER768A, SER778A, SER782A, SER788A, SER813A, THR133A, THR157A, THR169A, THR274C, THR282C, THR719A, THR730A, THR738A, TRP758A, TYR276C, TYR277C, TYR351C, TYR358C, TYR707A, TYR717A, TYR733A, VAL163A, VAL301C, VAL302C, VAL380C, VAL722A, VAL726A, VAL786A, VAL814A
• B-D: ALA284D, ALA725B, ALA732B, ALA784B, ALA787B, ALA812B, ARG132B, ARG289D, ARG293D, ARG328D, ARG329D, ARG362D, ARG705B, ARG716B, ARG721B, ARG729B, ARG741B, ARG762B, ARG765B, ARG772B, ARG790B, ARG820B, ASN294D, ASN365D, ASN699B, ASN700B, ASN713B, ASN739B, ASP281D, ASP290D, ASP306D, ASP347D, ASP350D, ASP374D, ASP378D, ASP696B, ASP702B, ASP710B, ASP735B, ASP757B, CYS292D, GLN165B, GLU124B, GLU130B, GLU168B, GLU304D, GLU305D, GLU330D, GLU332D, GLU333D, GLU344D, GLU345D, GLU353D, GLU357D, GLU363D, GLU364D, GLU375D, GLU379D, GLU384D, GLU697B, GLU724B, GLU761B, GLU771B, GLU785B, GLU809B, GLU817B, GLY128B, GLY720B, GLY740B, GLY759B, GLY766B, GLY769B, GLY770B, GLY789B, HIS366D, ILE126B, ILE129B, ILE160B, ILE280D, ILE288D, ILE331D, ILE372D, ILE736B, ILE755B, ILE760B, ILE775B, ILE811B, LEU127B, LEU170B, LEU173B, LEU176B, LEU177B, LEU275D, LEU285D, LEU335D, LEU346D, LEU349D, LEU354D, LEU359D, LEU369D, LEU370D, LEU373D, LEU376D, LEU377D, LEU701B, LEU703B, LEU704B, LEU708B, LEU737B, LEU767B, LEU774B, LEU783B, LEU791B, LEU815B, LEU818B, LYS172B, LYS178B, LYS180B, LYS273D, LYS278D, LYS279D, LYS286D, LYS326D, LYS348D, LYS356D, LYS360D, LYS361D, LYS368D, LYS371D, LYS381D, LYS706B, LYS711B, LYS728B, LYS756B, LYS810B, LYS816B, LYS823B, PHE164B, PHE291D, PHE295D, PHE352D, PHE355D, PHE709B, PHE714B, PHE718B, PHE742B, PRO763B, SER161B, SER166B, SER283D, SER287D, SER307D, SER327D, SER383D, SER712B, SER715B, SER768B, SER782B, SER788B, SER813B, THR133B, THR137B, THR169B, THR274D, THR282D, THR719B, THR730B, THR738B, TRP758B, TYR276D, TYR277D, TYR303D, TYR351D, TYR358D, TYR707B, TYR717B, TYR733B, VAL163B, VAL301D, VAL302D, VAL380D, VAL722B, VAL726B, VAL786B, VAL814B
• C-D: ALA70D, ARG80C, ARG80D, ARG83D, ASN104C, ASN104D, ASN64C, ASN65C, ASP112C, ASP112D, ASP73D, ASP76C, ASP76D, GLY103C, GLY103D, GLY98C, GLY98D, HIS72C, HIS72D, ILE109C, ILE109D, ILE113C, ILE113D, LEU101C, LEU101D, LEU71C, LEU71D, LEU74C, LEU74D, LEU75C, LEU75D, LEU78C, LEU78D, LEU99C, LEU99D, LYS100C, LYS100D, LYS79C, LYS79D, LYS97C, LYS97D, PHE102C, PHE102D, PHE105C, PHE105D, PHE115C, PHE115D, PRO66C, SER108C, SER108D, SER110C, SER110D, SER111C, SER111D, SER67C, SER67D, THR107C, THR107D, TRP96C, TRP96D, TYR77C, TYR77D, VAL106C, VAL106D, VAL68C, VAL68D, VAL69C, VAL69D, VAL87C, VAL87D