3QBY

crystal structure of the pwwp domain of human hepatoma-derived growth factor 2

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 31
  • Norm. En. per Res.: -5.5255
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-67.1962	10.5341	-114.627	-171.2891	31	6	0	3690	0	9	8
A-C	-11.6	0.0	-68.1704	-79.7704	39	4	0	3228	0	13	21
A-H	0.0	0.0	-0.0893	-0.0893	3	0	0	15	0	3	0
B-C	0.0	0.0	-17.3327	-17.3327	26	1	0	942	0	4	14
B-H	-13.1256	0.0	-19.2636	-32.3892	12	1	0	618	0	5	5

Interface residues

• A-B: ALA29A, ALA32A, ARG74B, ASN72B, ASN78B, ASP27A, ASP30A, GLU49B, GLU79B, GLY17B, GLY31A, GLY46B, GLY76B, HIS48B, ILE28A, LYS34A, LYS73B, LYS75B, PHE44B, PHE52A, PHE77B, PRO19B, PRO35A, PRO36A, PRO41A, PRO71B, PRO7A, THR47B, TRP21B, TYR18B, VAL33A
• A-C: ALA29A, ALA32A, ALA51A, ARG74A, ARG74C, ASN72C, ASP26A, ASP27A, ASP57C, GLU49A, GLY17A, GLY17C, GLY31A, HIS20C, ILE28A, ILE42A, LEU53A, LEU53C, LYS14C, LYS16A, LYS16C, LYS34A, LYS39A, LYS73C, LYS75C, MET15A, MET15C, PHE44A, PHE52A, PRO19A, PRO19C, PRO35A, PRO36A, PRO41A, PRO71C, THR50A, TYR18A, TYR18C, VAL33A
• A-H: ARG19H, ASP30A, HIS18H
• B-C: ARG74B, ASN38C, ASN72B, ASP57C, ASP66B, CYS64B, GLY17B, GLY54C, GLY69B, HIS20B, LEU53C, LYS14B, LYS16B, LYS16C, LYS39C, LYS56C, LYS67B, LYS70B, LYS73B, LYS75B, MET15C, PRO19B, PRO36C, PRO37C, TYR18B, TYR68B
• B-H: ALA51B, ARG19H, GLU49B, HIS18H, HIS48B, MET15B, PHE43B, PHE44B, PHE52B, SER93B, THR47B, THR50B