3QBQ

crystal structure of extracellular domains of mouse rank-rankl complex

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 74
  • Norm. En. per Res.: -5.6188
• Hub Node: B(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-93.6673	-146.1763	-175.945	-415.7886	74	16	1	7094	12	37	38
B-C	0.0	0.0	-18.1588	-18.1588	16	0	2	891	0	2	1
B-D	-23.2531	1.6992	-76.154	-97.7079	56	3	2	3533	0	13	13
C-D	-101.7662	-117.5872	-166.171	-385.5245	76	15	1	7585	9	37	38

Interface residues

• A-B: ALA117B, ALA171A, ALA172A, ALA193A, ALA304A, ALA95B, ALA98B, ARG111B, ARG129B, ARG130B, ARG190A, ARG222A, ASN122B, ASN131B, ASN170A, ASN266A, ASP189A, ASP299A, ASP301A, ASP303A, ASP75B, ASP85B, ASP94B, CYS115B, CYS125B, CYS127B, CYS128B, CYS220A, CYS87B, CYS93B, GLN302A, GLU126B, GLU225A, GLU268A, GLU76B, GLU84B, GLY118B, GLY191A, GLY265A, GLY73B, GLY96B, HIS120B, HIS223A, HIS224A, HIS270A, HIS90B, ILE169A, ILE174A, LEU297A, LEU298A, LEU88B, LEU89B, LEU99B, LYS194A, LYS86B, LYS91B, LYS97B, PHE269A, PHE271A, PRO300A, PRO74B, SER227A, SER267A, SER296A, THR116B, THR168A, THR226A, THR305A, TRP121B, TRP192A, TYR119B, TYR187A, TYR77B, VAL92B
• B-C: ALA171C, ALA172C, ARG190C, ASN170C, ASN175B, CYS176B, ILE169C, ILE174C, LEU178B, LEU179B, PRO172B, PRO300C, SER173C, THR174B, THR177B, TYR187C
• B-D: ALA101D, ALA114D, ALA95D, ALA98D, ARG111D, ARG112D, ASN106D, ASN175B, ASP103D, ASP168B, ASP75D, ASP94D, CYS113D, CYS170B, CYS176B, CYS195B, CYS93D, GLY105D, GLY180B, GLY73D, GLY96D, HIS107D, HIS142B, HIS90D, LEU144B, LEU178B, LEU179B, LEU182B, LEU70D, LEU89D, LEU99D, LYS169B, LYS171B, LYS181B, LYS55D, LYS91D, LYS97D, PHE159B, PRO104D, PRO172B, PRO71D, PRO74D, SER196B, SER197B, SER198B, SER65D, THR116D, THR167B, THR174B, THR177B, THR64D, TRP173B, VAL100B, VAL100D, VAL102D, VAL92D
• C-D: ALA117D, ALA171C, ALA172C, ALA193C, ALA304C, ALA95D, ALA98D, ARG111D, ARG129D, ARG130D, ARG190C, ARG222C, ASN122D, ASN131D, ASN170C, ASN266C, ASP189C, ASP299C, ASP301C, ASP303C, ASP75D, ASP94D, CYS115D, CYS125D, CYS127D, CYS128D, CYS220C, CYS87D, CYS93D, GLN302C, GLU126D, GLU225C, GLU268C, GLU76D, GLU84D, GLY118D, GLY191C, GLY73D, GLY96D, HIS120D, HIS166C, HIS188C, HIS223C, HIS224C, HIS270C, HIS90D, ILE169C, ILE174C, ILE195C, LEU297C, LEU298C, LEU88D, LEU89D, LEU99D, LYS194C, LYS86D, LYS91D, LYS97D, PHE164C, PHE269C, PHE271C, PRO300C, PRO74D, SER227C, SER267C, SER296C, THR116D, THR168C, THR226C, THR305C, TRP121D, TRP192C, TYR119D, TYR187C, TYR77D, VAL92D