3Q6M

crystal structure of human mc-hsp90 in c2221 space group

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 141
  • Norm. En. per Res.: -1.7096
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	23.4598	-264.513	-241.0532	141	17	11	14270	0	19	27
A-C	-4.0958	2.7072	-7.7636	-9.1521	24	0	0	547	0	8	15
B-C	-8.2397	23.511	-65.3429	-50.0717	36	4	2	2931	0	14	12

Interface residues

• A-B: ALA503A, ALA503B, ALA506A, ALA506B, ALA650A, ALA670A, ALA670B, ALA685A, ALA685B, ARG612A, ARG612B, ARG647A, ARG647B, ARG687A, ARG687B, ARG690A, ARG690B, ASN504A, ASN504B, ASN686A, ASN686B, ASP500A, ASP500B, ASP661A, ASP661B, ASP680A, ASP680B, ASP699B, CYS597A, CYS597B, CYS598A, CYS598B, GLN501A, GLN501B, GLN648A, GLN648B, GLN682A, GLN682B, GLU497A, GLU497B, GLU509A, GLU509B, GLU611B, GLU644A, GLU644B, GLU668A, GLU668B, GLU679A, GLU679B, GLY675A, GLY675B, GLY695A, GLY695B, GLY697A, GLY697B, HIS640A, HIS640B, HIS684A, HIS684B, ILE613A, ILE613B, ILE642A, ILE642B, ILE643A, ILE643B, ILE688A, ILE688B, ILE692A, ILE692B, ILE698B, LEU592B, LEU634A, LEU634B, LEU646A, LEU646B, LEU662A, LEU662B, LEU665A, LEU665B, LEU666A, LEU666B, LEU671A, LEU671B, LEU672A, LEU672B, LEU678A, LEU678B, LEU694A, LEU694B, LEU696A, LEU696B, LYS615A, LYS615B, LYS649A, LYS649B, LYS693A, LYS693B, MET614A, MET691A, MET691B, PHE507A, PHE507B, PHE676A, PHE676B, PRO596A, PRO596B, PRO681A, PRO681B, SER505A, SER505B, SER595A, SER595B, SER641A, SER641B, SER658A, SER658B, SER673A, SER673B, SER674A, SER674B, SER677A, SER677B, THR498A, THR594A, THR594B, THR645A, THR645B, THR669A, THR669B, THR683A, THR683B, TYR667A, TYR667B, TYR689A, TYR689B, VAL502A, VAL502B, VAL659A, VAL659B, VAL663A, VAL663B
• A-C: ARG456C, GLN334A, GLN405A, GLN531C, GLN532C, GLU380C, GLU451C, HIS450A, HIS450C, ILE408A, LEU447C, LYS407A, LYS407C, MET614A, MET614C, PRO395A, PRO395C, SER406A, SER406C, SER453C, TRP606C, TYR528A, TYR528C, TYR604C
• B-C: ALA347B, ARG345B, ARG346B, ARG366C, ARG367C, ARG386B, ASN318B, ASN360B, ASP319B, ASP322B, ASP390C, GLN440B, GLU321B, GLU392C, ILE296C, ILE370C, LEU316C, LYS294C, LYS314B, LYS362C, MET371C, PHE312C, PHE349B, PHE369C, PRO295C, PRO344B, PRO348B, PRO395C, SER315C, THR298C, THR317B, TRP297C, TRP320B, TYR364C, VAL365C, VAL368C