3Q2P

reduced sweetness of a monellin (mnei) mutant results from increased protein flexibility and disruption of a distant poly-(l-proline) ii helix

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 11
  • Norm. En. per Res.: -2.9774
• Hub Node: B(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-4.8471	8.618	-121.888	-118.1171	55	5	1	5294	0	12	14
B-C	0.0	-28.6135	-4.1382	-32.7516	11	0	0	257	2	6	8
B-D	0.0	6.1111	-20.1182	-14.0071	24	2	0	1049	0	4	7
C-D	-17.4	-7.1641	-143.947	-168.5111	58	4	1	5919	0	13	14

Interface residues

• A-B: ARG39A, ARG39B, ARG72A, ARG72B, ARG88A, ARG88B, ASN90A, ASN90B, ASP74A, ASP74B, CB8.72208-20.95699, CYS41A, CYS41B, GLN61A, GLN61B, GLU2A, GLU2A9, GLU2B, GLU4A, GLU4B, GLU59A, GLU59B, GLY1A, GLY1B, ILE38A, ILE46A, ILE46B, ILE5A, ILE5B, ILE6A, ILE6B, LEU70A, LEU87A, LEU87B, LYS43A, LYS43B, LYS44A, LYS44B, MET0B, MET42A, MET42B, PRO40A, PRO40B, PRO94A, PRO94B, PRO95A, PRO95B, PRO96A, PRO96B, TRP3A, TRP3B, TYR63A, TYR63B, VAL93A, VAL93B
• B-C: ARG88C, ASN35B, ASN49C, ASP68B, LEU87C, LYS56C, LYS69B, LYS85C, PRO92B, SER67B, THR33B
• B-D: ALA66B, ALA66D, ARG31B, ASN24B, ASN35B, ASN35D, ASP21B, ASP68B, ASP68D, ILE38D, LEU32B, LEU70D, LYS17B, LYS36D, LYS69D, PHE34B, PRO94D, PRO95D, PRO96D, SER67B, SER67D, THR33B, TYR65D, VAL93D
• C-D: ARG39C, ARG39D, ARG72C, ARG72D, ARG88C, ARG88D, ASN90C, ASN90D, ASP74C, ASP74D, CYS41C, CYS41D, GLN61C, GLN61D, GLU2C, GLU2D, GLU4C, GLU4D, GLU59C, GLU59D, GLY1C, GLY1D, ILE38C, ILE46C, ILE46D, ILE5C, ILE5D, ILE6C, ILE6D, LEU70C, LEU70D, LEU87C, LEU87D, LYS43C, LYS43D, LYS44C, LYS44D, MET42C, MET42D, PHE89C, PHE89D, PRO40C, PRO40D, PRO92C, PRO92D, PRO94C, PRO94D, PRO95C, PRO95D, PRO96C, PRO96D, TRP3C, TRP3D, TYR60C, TYR63C, TYR63D, VAL93C, VAL93D