3PWQ

the phenylacetyl-coa monooxygenase paaac subcomplex

• Total interactions analyzed: 66
• Total true interactions: 22
• Strongest Interaction:
  • Chains: G-H
  • Int. Res.: 178
  • Norm. En. per Res.: -3.3412
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-63.7456	-17.2594	-509.421	-590.4261	178	25	19	22058	0	50	38
A-B	-2.4834	4.9325	-102.509	-100.0599	44	3	3	4060	0	12	14
A-D	-33.454	-20.4723	-128.298	-182.2242	73	4	0	5455	7	32	30
A-J	0.0	-7.3598	-1.4545	-8.8143	15	0	0	204	0	9	7
A-R	0.0	-5.3916	-27.5113	-32.9029	25	5	0	1304	0	8	4
C-B	-37.0905	-28.5445	-146.976	-212.611	74	3	0	5910	8	33	31
C-I	-34.8736	6.2776	-122.621	-151.2171	70	5	1	5102	0	34	30
C-J	-13.6574	-63.0266	-129.543	-206.227	82	12	4	6253	4	26	23
C-R	0.0	-35.1078	-22.6502	-57.758	28	2	0	1121	2	11	16
B-D	-54.9644	-13.0424	-484.512	-552.5188	176	26	19	21386	0	49	37
B-K	0.0	0.0	-0.1058	-0.1058	5	0	0	33	0	7	6
D-K	-48.24	-74.8725	-126.368	-249.4805	90	22	5	6673	3	33	24
E-F	-58.8955	-13.2725	-479.53	-551.698	178	26	19	21428	0	52	39
E-G	0.0	4.9954	-101.411	-96.4156	44	2	3	4057	0	12	14
E-H	-29.5487	-23.0747	-132.09	-184.7134	72	3	0	5518	7	33	31
E-R	0.0	0.0	-0.0445	-0.0445	9	0	0	21	0	8	8
F-G	-34.8277	-27.2932	-143.229	-205.3499	73	4	0	5829	8	33	30
F-J	-33.2419	3.3859	-120.738	-150.594	72	6	1	5175	0	35	30
F-R	-9.0471	-44.7189	-120.616	-174.382	83	8	5	6003	2	28	24
G-H	-64.8449	-14.7542	-515.133	-594.7322	178	23	19	22170	0	50	39
I-J	0.0	-8.6442	-3.9571	-12.6012	16	0	0	371	0	10	3
J-R	0.0	-5.8227	-7.6318	-13.4545	22	0	0	779	0	14	7

Interface residues

• A-C: ALA116C, ALA158A, ALA165C, ALA168C, ALA175C, ALA206A, ALA234A, ALA281C, ALA285C, ALA295C, ALA296C, ALA298C, ALA29A, ALA300C, ALA37A, ALA39A, ALA39C, ALA49A, ALA56C, ALA63C, ALA67C, ALA69A, ALA73C, ALA91A, ARG143A, ARG21A, ARG241A, ARG278C, ARG293C, ARG50A, ARG55C, ARG60C, ARG61C, ARG72A, ARG90C, ASN146A, ASN40A, ASN51A, ASN51C, ASN87A, ASN89A, ASP149A, ASP280C, ASP35A, ASP44A, ASP64A, ASP66A, ASP71C, ASP92A, CYS166C, CYS26A, GLN153A, GLN171C, GLN176C, GLN20A, GLN237A, GLN240A, GLN246A, GLN247A, GLN301C, GLN70C, GLU142A, GLU164C, GLU174C, GLU205A, GLU235A, GLU24A, GLU277C, GLU287C, GLU288C, GLU294C, GLU31A, GLU33A, GLU42C, GLU49C, GLU65A, GLU72C, GLY12A, GLY139A, GLY145A, GLY147A, GLY152A, GLY172C, GLY23A, GLY245A, GLY27A, GLY289C, GLY42A, GLY47A, GLY50C, GLY74C, GLY76C, GLY88A, HIS158C, HIS28A, HIS299C, HIS40C, HIS75C, ILE34A, ILE41A, ILE43C, ILE53C, ILE64C, ILE94A, LEU113C, LEU141A, LEU144A, LEU169C, LEU16A, LEU22A, LEU233A, LEU239A, LEU243A, LEU297C, LEU32A, LEU36A, LEU38A, LEU43A, LEU45A, LEU46A, LEU47C, LEU53A, LEU59C, LEU65C, LEU66C, LEU68A, LEU77C, LEU79C, LYS154A, LYS177C, LYS282C, LYS284C, LYS302C, LYS62C, LYS68C, MET155A, MET167C, MET179C, MET232A, MET236A, MET46C, PHE70A, PHE77A, PHE90A, PRO244A, PRO30A, PRO48C, PRO57C, SER114C, SER151A, SER173C, SER19A, SER54A, SER81C, THR148A, THR207A, THR290C, THR54C, THR58C, THR67A, THR93A, TRP115C, TRP140A, TRP248A, TRP25A, TRP286C, TRP291C, TRP52C, TYR238A, TYR78C, TYR80C, TYR94C, VAL150A, VAL17A, VAL242A, VAL292C, VAL44C, VAL69C
• A-B: ALA234A, ALA234B, ARG241A, ARG241B, ARG72A, ARG72B, ARG75A, ASP73A, ASP73B, GLN237A, GLN237B, GLN240A, GLN240B, GLU235A, GLU235B, GLU74A, GLU74B, GLY230A, GLY230B, LEU229A, LEU233A, LEU233B, LEU239A, LEU239B, LEU243A, LEU243B, MET232A, MET232B, MET236A, MET236B, PHE70A, PHE70B, PHE77A, PHE77B, PRO231A, PRO231B, PRO244A, PRO244B, THR71A, THR71B, TYR238A, TYR238B, VAL242A, VAL242B
• A-D: ALA175D, ALA183D, ALA215A, ALA234A, ARG164A, ARG186D, ARG217A, ARG271D, ARG278D, ARG55D, ARG75A, ASN109D, ASN160A, ASN185D, ASN275D, ASN51D, ASP117D, ASP182D, ASP280D, ASP73A, CYS274D, GLN178D, GLN214A, GLN276D, GLN76A, GLN85A, GLU213A, GLU227A, GLU235A, GLU266D, GLU277D, GLU49D, GLU74A, GLU84A, GLY219A, GLY223A, GLY230A, GLY270D, GLY272D, GLY88A, HIS225A, HIS228A, ILE118D, ILE121D, ILE273D, LEU113D, LEU162A, LEU224A, LEU229A, LEU233A, LEU47D, LEU81A, LYS161A, LYS284D, MET179D, MET232A, PHE108D, PHE165A, PHE187D, PRO111D, PRO231A, PRO48D, PRO86A, SER114D, THR112D, THR218A, THR226A, THR54D, TRP115D, TRP52D, TYR110D, TYR216A, VAL267D
• A-J: ALA121A, ARG50A, ARG50J, ASN51A, ASP64J, ASP66J, GLN118A, GLU62J, GLY61J, GLY63J, LYS125A, LYS128A, PRO117A, THR67J, THR71J
• A-R: ALA197R, ALA201R, ALA206R, ARG131A, ARG135A, ARG138R, ASN146R, ASN204R, ASN209R, GLU142R, GLU198R, GLU205R, GLY202R, ILE127A, ILE203R, LEU208R, LYS128A, MET112A, PHE136A, PHE200R, THR109A, THR207R, TYR132A, VAL105A, VAL210R
• C-B: ALA175C, ALA183C, ALA215B, ALA234B, ARG164B, ARG186C, ARG217B, ARG271C, ARG278C, ARG55C, ARG75B, ASN109C, ASN160B, ASN185C, ASN269C, ASN275C, ASN51C, ASP117C, ASP182C, ASP280C, ASP73B, CYS274C, GLN178C, GLN214B, GLN276C, GLN76B, GLN85B, GLU213B, GLU227B, GLU235B, GLU266C, GLU277C, GLU49C, GLU74B, GLU84B, GLY219B, GLY223B, GLY230B, GLY270C, GLY272C, HIS225B, HIS228B, ILE118C, ILE121C, ILE273C, LEU113C, LEU162B, LEU224B, LEU229B, LEU233B, LEU47C, LEU81B, LYS161B, LYS222B, LYS284C, MET179C, MET232B, PHE108C, PHE165B, PHE187C, PRO111C, PRO231B, PRO48C, PRO86B, SER114C, THR112C, THR218B, THR226B, THR54C, TRP115C, TRP52C, TYR110C, TYR216B, VAL267C
• C-I: ALA170C, ALA6I, ARG164I, ARG217I, ARG224C, ARG255C, ARG72I, ARG75I, ASN228C, ASN2I, ASP173I, ASP227C, ASP242C, ASP244C, ASP248C, ASP73I, GLN171C, GLN181C, GLN223C, GLN232C, GLN76I, GLU174C, GLU174I, GLU227I, GLU234C, GLU250C, GLU74I, GLU84I, GLY219I, GLY220I, GLY223I, GLY230I, GLY237C, GLY252C, HIS225I, HIS228I, HIS246C, HIS253C, ILE175I, LEU224I, LEU229I, LEU236C, LEU245C, LEU68I, LEU81I, LEU9I, LYS177C, LYS221I, LYS222I, MET167C, MET235C, MET238C, PHE247C, PHE256C, PHE77I, PRO231C, PRO231I, PRO243C, SER78I, THR218I, THR226I, THR229C, THR239C, THR249C, TYR216I, TYR254C, VAL226C, VAL230C, VAL233C, VAL240C
• C-J: ALA135C, ALA145C, ALA29J, ALA37J, ALA39J, ARG138C, ARG160C, ARG21J, ARG222C, ARG224C, ARG50J, ARG60C, ARG61C, ASN132C, ASN228C, ASN40J, ASN51J, ASP227C, ASP35J, ASP44J, CYS137C, CYS152C, CYS26J, GLN133C, GLN159C, GLN161C, GLN171C, GLN20J, GLN223C, GLN232C, GLN48J, GLU129J, GLU154C, GLU155C, GLU164C, GLU220C, GLU235J, GLU24J, GLU31J, GLU33J, GLU65J, GLY127C, GLY23J, GLY27J, GLY42J, GLY47J, HIS133J, HIS158C, HIS28J, ILE130C, ILE151C, ILE34J, ILE41J, ILE64C, LEU136C, LEU221C, LEU22J, LEU32J, LEU36J, LEU43J, LEU45J, LEU46J, LYS125J, LYS128J, LYS150C, LYS153C, MET148C, MET235C, PHE157C, PHE195C, PHE216C, PHE225C, PRO231C, PRO30J, SER156C, SER19J, SER54J, TRP25J, TYR132J, VAL131C, VAL134C, VAL149C
• C-R: ALA16C, ALA185R, ARG10C, ARG110R, ARG115R, ARG146C, ARG6C, ASP187R, ASP21C, GLN20C, GLU113R, GLU181R, GLU182R, GLU18C, GLY142C, GLY183R, ILE177R, ILE17C, ILE184R, LEU179R, PRO143C, PRO19C, SER114R, SER180R, THR15C, THR190R, THR85C, VAL186R
• B-D: ALA116D, ALA158B, ALA165D, ALA168D, ALA175D, ALA206B, ALA234B, ALA281D, ALA285D, ALA295D, ALA296D, ALA298D, ALA29B, ALA300D, ALA37B, ALA39B, ALA39D, ALA49B, ALA56D, ALA63D, ALA67D, ALA69B, ALA73D, ALA91B, ARG143B, ARG21B, ARG241B, ARG278D, ARG293D, ARG50B, ARG55D, ARG60D, ARG61D, ARG72B, ARG90D, ASN146B, ASN40B, ASN51B, ASN51D, ASN87B, ASN89B, ASP149B, ASP280D, ASP35B, ASP44B, ASP64B, ASP66B, ASP71D, ASP92B, CYS166D, CYS26B, GLN153B, GLN171D, GLN176D, GLN178D, GLN20B, GLN237B, GLN240B, GLN246B, GLN247B, GLN301D, GLN48B, GLN70D, GLU142B, GLU164D, GLU174D, GLU205B, GLU235B, GLU24B, GLU277D, GLU287D, GLU288D, GLU294D, GLU31B, GLU33B, GLU42D, GLU49D, GLU65B, GLU72D, GLY139B, GLY145B, GLY147B, GLY152B, GLY172D, GLY23B, GLY245B, GLY27B, GLY289D, GLY42B, GLY47B, GLY50D, GLY74D, GLY76D, GLY88B, HIS158D, HIS28B, HIS299D, HIS75D, ILE34B, ILE41B, ILE43D, ILE53D, ILE64D, ILE94B, LEU113D, LEU141B, LEU144B, LEU169D, LEU16B, LEU22B, LEU233B, LEU239B, LEU243B, LEU297D, LEU32B, LEU36B, LEU38B, LEU43B, LEU45B, LEU46B, LEU47D, LEU53B, LEU59D, LEU65D, LEU66D, LEU68B, LEU77D, LEU79D, LYS154B, LYS177D, LYS282D, LYS284D, LYS302D, LYS62D, LYS68D, MET155B, MET179D, MET232B, MET236B, MET46D, PHE70B, PHE77B, PHE90B, PRO244B, PRO30B, PRO57D, SER114D, SER151B, SER173D, SER19B, SER54B, SER81D, THR148B, THR207B, THR290D, THR54D, THR58D, THR67B, THR93B, TRP115D, TRP140B, TRP248B, TRP25B, TRP286D, TRP291D, TRP52D, TYR238B, TYR78D, TYR80D, TYR94D, VAL150B, VAL17B, VAL242B, VAL292D, VAL44D, VAL69D
• B-K: ASN51B, ASP64K, GLY63K, LYS125B, THR67K
• D-K: ALA135D, ALA145D, ALA29K, ALA37K, ALA39K, ALA49K, ARG138D, ARG160D, ARG215D, ARG222D, ARG224D, ARG50K, ARG60D, ARG61D, ASN132D, ASN228D, ASN40K, ASN51K, ASP227D, ASP35K, ASP44K, ASP66K, CYS137D, CYS152D, CYS26K, GLN133D, GLN159D, GLN161D, GLN171D, GLN20K, GLN223D, GLN232D, GLN48K, GLU129K, GLU154D, GLU155D, GLU164D, GLU220D, GLU234D, GLU24K, GLU31K, GLU33K, GLU65K, GLY127D, GLY23K, GLY252D, GLY27K, GLY42K, GLY47K, HIS133K, HIS158D, HIS253D, HIS28K, ILE130D, ILE34K, ILE41K, ILE64D, LEU136D, LEU221D, LEU32K, LEU36K, LEU38K, LEU43K, LEU45K, LEU46K, LYS125K, LYS128K, LYS150D, LYS153D, MET148D, MET167D, MET235D, PHE157D, PHE163D, PHE195D, PHE216D, PHE225D, PHE70K, PRO231D, PRO30K, SER156D, SER54K, THR217D, THR229D, TRP25K, TYR132K, VAL131D, VAL134D, VAL149D, VAL230D
• E-F: ALA116F, ALA158E, ALA165F, ALA168F, ALA175F, ALA206E, ALA234E, ALA281F, ALA285F, ALA295F, ALA296F, ALA298F, ALA29E, ALA300F, ALA37E, ALA39E, ALA39F, ALA49E, ALA56F, ALA63F, ALA67F, ALA69E, ALA73F, ALA91E, ARG143E, ARG21E, ARG241E, ARG278F, ARG293F, ARG50E, ARG55F, ARG60F, ARG61F, ARG72E, ARG90F, ASN146E, ASN40E, ASN51E, ASN51F, ASN87E, ASN89E, ASP149E, ASP35E, ASP44E, ASP64E, ASP66E, ASP71F, ASP92E, CYS166F, CYS26E, GLN153E, GLN171F, GLN176F, GLN178F, GLN20E, GLN237E, GLN240E, GLN246E, GLN247E, GLN303F, GLN48E, GLN70F, GLU142E, GLU164F, GLU174F, GLU205E, GLU235E, GLU24E, GLU277F, GLU287F, GLU288F, GLU294F, GLU31E, GLU33E, GLU42F, GLU49F, GLU65E, GLU72F, GLY12E, GLY139E, GLY145E, GLY147E, GLY152E, GLY172F, GLY23E, GLY245E, GLY27E, GLY289F, GLY42E, GLY47E, GLY50F, GLY74F, GLY76F, GLY88E, HIS158F, HIS28E, HIS299F, HIS75F, ILE34E, ILE41E, ILE43F, ILE53F, ILE64F, ILE94E, LEU113F, LEU141E, LEU144E, LEU169F, LEU16E, LEU22E, LEU233E, LEU239E, LEU243E, LEU297F, LEU32E, LEU36E, LEU38E, LEU43E, LEU45E, LEU46E, LEU47F, LEU53E, LEU59F, LEU65F, LEU66F, LEU68E, LEU77F, LEU79F, LYS154E, LYS177F, LYS282F, LYS284F, LYS302F, LYS62F, LYS68F, MET155E, MET167F, MET179F, MET232E, MET236E, MET46F, PHE70E, PHE77E, PHE90E, PRO244E, PRO30E, PRO48F, PRO57F, SER114F, SER151E, SER173F, SER19E, SER54E, SER81F, THR148E, THR207E, THR290F, THR54F, THR58F, THR67E, THR93E, TRP115F, TRP140E, TRP248E, TRP25E, TRP286F, TRP291F, TRP52F, TYR238E, TYR78F, TYR80F, TYR94F, VAL150E, VAL17E, VAL242E, VAL292F, VAL44F, VAL69F
• E-G: ALA234E, ALA234G, ARG241E, ARG241G, ARG72E, ARG72G, ARG75G, ASP73E, ASP73G, GLN237E, GLN237G, GLN240E, GLN240G, GLU235E, GLU235G, GLU74E, GLU74G, GLY230E, GLY230G, LEU229G, LEU233E, LEU233G, LEU239E, LEU239G, LEU243E, LEU243G, MET232E, MET232G, MET236E, MET236G, PHE70E, PHE70G, PHE77E, PHE77G, PRO231E, PRO231G, PRO244E, PRO244G, THR71E, THR71G, TYR238E, TYR238G, VAL242E, VAL242G
• E-H: ALA175H, ALA183H, ALA215E, ALA234E, ARG164E, ARG186H, ARG217E, ARG271H, ARG278H, ARG55H, ARG75E, ASN109H, ASN160E, ASN185H, ASN275H, ASN51H, ASP117H, ASP182H, ASP280H, ASP73E, CYS274H, GLN178H, GLN214E, GLN276H, GLN76E, GLN85E, GLU213E, GLU227E, GLU235E, GLU266H, GLU277H, GLU49H, GLU74E, GLU84E, GLY219E, GLY223E, GLY230E, GLY270H, GLY272H, HIS225E, HIS228E, ILE118H, ILE121H, ILE273H, LEU113H, LEU224E, LEU229E, LEU233E, LEU47H, LEU81E, LYS161E, LYS222E, LYS284H, MET179H, MET232E, PHE108H, PHE165E, PHE187H, PRO111H, PRO231E, PRO48H, PRO86E, SER114H, THR112H, THR218E, THR226E, THR54H, TRP115H, TRP52H, TYR110H, TYR216E, VAL267H
• E-R: ALA121E, ARG50E, ARG50R, ASN51E, ASP64R, GLN118E, GLU62R, GLY61R, GLY63R
• F-G: ALA175F, ALA183F, ALA215G, ALA234G, ARG164G, ARG186F, ARG217G, ARG271F, ARG278F, ARG55F, ARG75G, ASN109F, ASN160G, ASN185F, ASN275F, ASN51F, ASP117F, ASP182F, ASP280F, ASP73G, CYS274F, GLN178F, GLN214G, GLN276F, GLN76G, GLN85G, GLU213G, GLU227G, GLU235G, GLU266F, GLU277F, GLU49F, GLU74G, GLU84G, GLY219G, GLY223G, GLY230G, GLY270F, GLY272F, HIS225G, HIS228G, ILE118F, ILE121F, ILE273F, LEU113F, LEU162G, LEU224G, LEU229G, LEU233G, LEU47F, LEU81G, LYS161G, LYS222G, LYS284F, MET179F, MET232G, PHE108F, PHE165G, PHE187F, PRO111F, PRO231G, PRO48F, PRO86G, SER114F, THR112F, THR218G, THR226G, THR54F, TRP115F, TRP52F, TYR110F, TYR216G, VAL267F
• F-J: ALA170F, ALA215J, ALA6J, ARG164J, ARG217J, ARG224F, ARG255F, ARG72J, ARG75J, ASN228F, ASN2J, ASP173J, ASP227F, ASP242F, ASP244F, ASP248F, ASP73J, GLN171F, GLN178F, GLN181F, GLN223F, GLN232F, GLN76J, GLU174F, GLU174J, GLU227J, GLU234F, GLU250F, GLU74J, GLU84J, GLY219J, GLY220J, GLY223J, GLY230J, GLY237F, GLY252F, HIS225J, HIS228J, HIS246F, HIS253F, ILE175J, LEU224J, LEU229J, LEU236F, LEU245F, LEU81J, LEU9J, LYS177F, LYS221J, LYS222J, MET167F, MET235F, MET238F, PHE165J, PHE247F, PHE77J, PRO231F, PRO231J, PRO243F, SER78J, THR218J, THR226J, THR229F, THR239F, THR249F, THR5J, TYR216J, TYR254F, VAL226F, VAL230F, VAL233F, VAL240F
• F-R: ALA128F, ALA129F, ALA135F, ALA145F, ALA29R, ALA37R, ALA39R, ARG138F, ARG160F, ARG215F, ARG224F, ARG50R, ARG60F, ARG61F, ASN132F, ASN228F, ASN40R, ASN51R, ASP227F, ASP35R, ASP44R, CYS137F, CYS152F, CYS26R, GLN133F, GLN159F, GLN161F, GLN171F, GLN232F, GLN48R, GLU129R, GLU154F, GLU155F, GLU164F, GLU220F, GLU234F, GLU24R, GLU31R, GLU33R, GLU65R, GLY127F, GLY23R, GLY27R, GLY42R, GLY47R, HIS133R, HIS158F, HIS28R, ILE130F, ILE151F, ILE34R, ILE41R, ILE64F, LEU136F, LEU221F, LEU32R, LEU36R, LEU38R, LEU43R, LEU45R, LEU46R, LYS125R, LYS128R, LYS150F, LYS153F, MET148F, MET167F, MET235F, PHE157F, PHE163F, PHE195F, PHE216F, PHE225F, PRO231F, PRO30R, SER156F, SER54R, THR229F, TRP25R, TYR132R, VAL131F, VAL134F, VAL149F
• G-H: ALA116H, ALA158G, ALA165H, ALA168H, ALA175H, ALA206G, ALA234G, ALA281H, ALA285H, ALA295H, ALA296H, ALA298H, ALA29G, ALA300H, ALA37G, ALA39G, ALA39H, ALA49G, ALA56H, ALA63H, ALA67H, ALA69G, ALA73H, ALA91G, ARG143G, ARG21G, ARG241G, ARG278H, ARG293H, ARG50G, ARG55H, ARG60H, ARG61H, ARG72G, ARG90H, ASN146G, ASN40G, ASN51G, ASN51H, ASN87G, ASN89G, ASP149G, ASP280H, ASP35G, ASP44G, ASP64G, ASP66G, ASP71H, ASP92G, CYS166H, CYS26G, GLN153G, GLN171H, GLN176H, GLN20G, GLN237G, GLN240G, GLN246G, GLN247G, GLN301H, GLN70H, GLU142G, GLU164H, GLU174H, GLU205G, GLU235G, GLU24G, GLU277H, GLU287H, GLU288H, GLU294H, GLU31G, GLU33G, GLU42H, GLU49H, GLU65G, GLU72H, GLY12G, GLY139G, GLY145G, GLY147G, GLY152G, GLY172H, GLY23G, GLY245G, GLY27G, GLY289H, GLY42G, GLY47G, GLY50H, GLY74H, GLY76H, GLY88G, HIS158H, HIS28G, HIS299H, HIS40H, HIS75H, ILE34G, ILE41G, ILE43H, ILE53H, ILE64H, ILE94G, LEU113H, LEU141G, LEU144G, LEU169H, LEU16G, LEU22G, LEU233G, LEU239G, LEU243G, LEU297H, LEU32G, LEU36G, LEU38G, LEU43G, LEU45G, LEU46G, LEU47H, LEU53G, LEU59H, LEU65H, LEU66H, LEU68G, LEU77H, LEU79H, LYS154G, LYS177H, LYS282H, LYS284H, LYS302H, LYS62H, LYS68H, MET155G, MET167H, MET179H, MET232G, MET236G, MET46H, PHE70G, PHE77G, PHE90G, PRO244G, PRO30G, PRO48H, PRO57H, SER114H, SER151G, SER173H, SER19G, SER54G, SER81H, THR148G, THR207G, THR290H, THR54H, THR58H, THR67G, THR93G, TRP115H, TRP140G, TRP248G, TRP25G, TRP286H, TRP291H, TRP52H, TYR238G, TYR78H, TYR80H, TYR94H, VAL150G, VAL17G, VAL242G, VAL292H, VAL44H, VAL69H
• I-J: ALA234I, ARG131J, ARG135J, ARG75I, ASP73I, GLN237I, GLU235I, GLU33J, GLU74I, GLY230I, LEU233I, LYS128J, MET236I, PRO231I, TYR132J, TYR238I
• J-R: ALA234J, ARG131R, ARG135R, ARG138R, ARG72J, ARG75J, ASP73J, GLN237J, GLU198R, GLU205R, GLU235J, GLU33R, GLU74J, GLY230J, LEU134R, LEU233J, LYS128R, PRO231J, THR71J, TYR132R, TYR238J, VAL105R