3PSK

crystal structure of the spt6 tandem sh2 domain from saccharomyces cerevisiae, form native spt6 (1247-1451)

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 58
  • Norm. En. per Res.: -2.7597
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	42.1536	-95.3474	-53.1938	73	4	0	4262	0	30	29
A-C	-31.417	0.0	-128.643	-160.06	58	7	3	4886	0	5	7
A-D	-55.6131	18.1366	-126.948	-164.4245	69	8	3	5600	0	22	19
B-C	-60.2856	14.5392	-166.576	-212.3224	90	6	3	7753	0	22	19
B-D	0.0	0.0	-38.6064	-38.6064	35	1	0	1848	0	1	2

Interface residues

• A-B: ARG1272A, ARG1272B, ARG1276A, ARG1276B, ARG1345A, ARG1345B, ASN1342A, ASN1342B, ASN1348A, ASN1348B, ASN1432A, ASP1298A, ASP1298B, ASP1300B, CYS1431A, CYS1431B, GLN1341A, GLN1341B, GLN1429A, GLN1429B, GLU1275A, GLU1275B, GLU1278A, GLU1278B, GLU1349A, GLU1349B, GLU1354A, GLU1354B, GLY1277A, GLY1277B, ILE1428A, ILE1428B, LEU1297A, LEU1297B, LEU1346A, LEU1346B, LEU1347A, LEU1347B, LYS1274A, LYS1274B, LYS1296A, LYS1296B, LYS1299A, LYS1299B, LYS1355A, LYS1355B, LYS1435A, LYS1435B, MET1350A, MET1350B, PHE1279A, PHE1279B, PHE1383A, PRO1425A, SER1273A, SER1352A, SER1352B, SER1353A, SER1353B, SER1426A, SER1426B, THR1351A, THR1351B, TYR1258A, TYR1258B, TYR1381A, TYR1381B, TYR1417A, TYR1417B, VAL1344A, VAL1344B, VAL1427A, VAL1427B
• A-C: ALA1317A, ALA1401C, ARG1252A, ASN1255A, ASN1314A, ASN1330A, ASN1400C, ASN1402C, ASN1421C, ASN1432C, ASP1331A, ASP1333A, CYS1431C, GLN1334A, GLN1341A, GLU1278A, GLU1313A, GLU1338A, GLY1433C, HIS1251A, HIS1256A, ILE1254A, ILE1336A, ILE1399C, LEU1316A, LEU1318A, LEU1332A, LEU1395C, LEU1405C, LEU1419C, LYS1274A, LYS1398C, LYS1404C, LYS1435C, MET1396C, PHE1260A, PHE1279A, PHE1397C, PHE1434C, PRO1257A, PRO1261A, SER1379C, SER1403C, THR1407C, THR1436C, TRP1408C, TYR1258A, TYR1259A, TYR1270A, TYR1381C, TYR1406C, TYR1422C, TYR1424C, VAL1253A, VAL1337A, VAL1344A, VAL1380C, VAL1420C
• A-D: ASN1326A, ASN1326D, ASN1330A, ASN1330D, ASN1421A, ASN1421D, ASN1423A, ASN1423D, ASN1432A, ASP1289A, ASP1289D, ASP1325A, ASP1325D, GLN1308A, GLN1308D, GLN1327A, GLN1327D, GLN1334A, GLN1334D, GLN1429A, GLN1429D, GLU1309A, GLU1309D, GLU1311A, GLU1311D, GLU1338A, GLY1319D, GLY1416D, GLY1433A, HIS1290A, HIS1290D, ILE1323A, ILE1323D, ILE1428A, LEU1310A, LEU1310D, LEU1322A, LEU1322D, LEU1419D, LEU1430A, LEU1437A, LEU1437D, LYS1312A, LYS1312D, LYS1320A, LYS1320D, LYS1328A, LYS1328D, PHE1418D, PRO1425A, PRO1425D, SER1426A, SER1426D, THR1415A, THR1415D, THR1436A, THR1436D, TYR1329A, TYR1329D, TYR1417D, TYR1422A, TYR1422D, TYR1424A, TYR1424D, VAL1321A, VAL1321D, VAL1324A, VAL1324D, VAL1420D
• B-C: ARG1345B, ARG1345C, ASN1326B, ASN1326C, ASN1330B, ASN1330C, ASN1342B, ASN1342C, ASN1421B, ASN1421C, ASN1423B, ASN1423C, ASN1432B, ASN1432C, ASP1289B, ASP1289C, ASP1325B, ASP1325C, CYS1431B, CYS1431C, GLN1308B, GLN1308C, GLN1327B, GLN1327C, GLN1334B, GLN1334C, GLN1429B, GLN1429C, GLU1309B, GLU1309C, GLU1311B, GLU1311C, GLU1338B, GLU1338C, GLU1349B, GLU1349C, GLY1416B, GLY1416C, GLY1433B, GLY1433C, HIS1290B, HIS1290C, ILE1323B, ILE1323C, ILE1428B, ILE1428C, LEU1310B, LEU1310C, LEU1322B, LEU1322C, LEU1346B, LEU1346C, LEU1419B, LEU1419C, LEU1430B, LEU1430C, LEU1437B, LYS1312B, LYS1312C, LYS1320B, LYS1320C, LYS1328B, LYS1328C, LYS1435B, PHE1418B, PHE1418C, PHE1434B, PHE1434C, PRO1425B, PRO1425C, SER1426B, SER1426C, THR1415B, THR1415C, THR1436B, THR1436C, TYR1329B, TYR1329C, TYR1417B, TYR1417C, TYR1422B, TYR1422C, TYR1424B, TYR1424C, VAL1321B, VAL1321C, VAL1324B, VAL1324C, VAL1427B, VAL1427C
• B-D: ALA1317B, ASN1255B, ASN1400D, ASN1421D, ASP1333B, GLN1341B, GLY1433D, HIS1256B, ILE1254B, ILE1336B, ILE1399D, LEU1318B, LEU1405D, LEU1419D, LEU1437D, LEU1438D, LYS1404D, PHE1260B, PHE1279B, PHE1397D, PHE1434D, PRO1257B, SER1403D, THR1407D, THR1436D, TRP1408D, TYR1258B, TYR1259B, TYR1270B, TYR1406D, TYR1422D, TYR1424D, VAL1253B, VAL1337B, VAL1420D