3PS4

pdz domain from human microtubule-associated serine/threonine-protein kinase 1

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-D
  • Int. Res.: 140
  • Norm. En. per Res.: -5.666
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-31.5652	-8.7718	-76.75	-117.0869	41	3	0	2777	0	4	2
A-C	0.0	0.0	-4.7774	-4.7774	18	0	0	387	0	4	4
A-D	-202.8613	-89.6187	-500.759	-793.239	140	29	17	19062	3	28	21
B-C	-177.1739	-41.046	-398.032	-616.2519	133	32	13	15916	2	25	21
B-D	0.0	0.0	-2.7806	-2.7806	18	0	0	341	0	3	1
C-D	0.0	0.0	-0.9033	-0.9033	16	0	0	229	0	12	8

Interface residues

• A-B: ALA1009A, ALA1009B, ALA1012A, ALA1012B, ARG965B, ASN1056A, ASN1056B, ASP1018A, CYS1015A, CYS1015B, GLN1010A, GLN1010B, GLN1058A, GLN1058B, GLU1004A, GLU1005A, GLU1011A, GLU1011B, GLU1055A, GLU1055B, GLY1006A, GLY1007A, GLY1013A, GLY1013B, ILE968A, ILE968B, LEU1014A, LEU1014B, PHE1054A, PHE1054B, PRO1008A, PRO1053A, PRO1053B, PRO967A, PRO967B, SER1059B, SER966A, SER966B, THR1057A, THR1057B, THR969A
• A-C: ALA983C, ARG985C, ASN1056A, ASP992C, GLN1010A, GLN1058A, GLU1005A, GLU1035C, GLU1038C, HIS1033C, LEU1060A, PRO1034C, SER1059A, THR1057A, TYR987C, TYR994C, VAL1032C, VAL1037C
• A-D: ALA1009A, ALA1009D, ALA1016A, ALA1016D, ALA983A, ALA983D, ARG965D, ARG972A, ARG972D, ARG982A, ARG982D, ARG985A, ARG985D, ASN1056A, ASN1056D, ASP1018A, ASP1018D, ASP990A, ASP990D, ASP992A, ASP992D, CYS1015A, CYS1015D, GLN1058A, GLN1058D, GLU1004A, GLU1004D, GLU1026D, GLU1038A, GLU1038D, GLU1055A, GLU1055D, GLY1017A, GLY1017D, GLY1025D, GLY1030D, GLY978A, GLY978D, GLY989A, GLY989D, HIS1002A, HIS1002D, HIS1022A, HIS1022D, HIS1029A, HIS1029D, HIS1033A, HIS1033D, HIS997A, HIS997D, HIS998A, HIS998D, ILE1020A, ILE1020D, ILE1040A, ILE1040D, ILE970A, ILE970D, ILE984A, ILE984D, ILE999A, ILE999D, LEU1014A, LEU1014D, LEU1019A, LEU1019D, LEU1041A, LEU1041D, LEU1060A, LEU1060D, LEU981A, LEU981D, LYS975A, LYS975D, LYS976A, LYS976D, MET0D, MET988A, MET988D, PHE1054A, PHE1054D, PHE979A, PHE979D, PRO1008A, PRO1008D, PRO1027A, PRO1027D, PRO1034A, PRO1034D, PRO1053A, PRO1053D, SER-1D, SER1059A, SER1059D, SER995A, SER995D, THR1021A, THR1021D, THR1050A, THR1050D, THR1051A, THR1051D, THR1052A, THR1052D, THR1057A, THR1057D, THR980A, THR980D, THR991A, THR991D, TRP1001A, TRP1001D, TYR977A, TYR977D, TYR987A, TYR987D, TYR994A, TYR994D, VAL1000A, VAL1000D, VAL1003A, VAL1003D, VAL1028D, VAL1032D, VAL1036A, VAL1036D, VAL1037A, VAL1037D, VAL1047A, VAL1047D, VAL1049A, VAL1049D, VAL1061A, VAL1061D, VAL986A, VAL986D, VAL993A, VAL993D, VAL996A, VAL996D
• B-C: ALA1009B, ALA1009C, ALA1016B, ALA1016C, ALA983B, ALA983C, ARG965B, ARG972B, ARG972C, ARG982B, ARG982C, ARG985B, ARG985C, ASN1056B, ASN1056C, ASP1018B, ASP1018C, ASP990B, ASP990C, ASP992C, CYS1015B, CYS1015C, GLN1058B, GLN1058C, GLU1004B, GLU1004C, GLU1038B, GLU1038C, GLU1055B, GLU1055C, GLY1017B, GLY1017C, GLY1025B, GLY1030C, GLY978B, GLY978C, GLY989B, GLY989C, HIS1002B, HIS1002C, HIS1022B, HIS1022C, HIS1029B, HIS1029C, HIS1033B, HIS1033C, HIS997B, HIS997C, HIS998B, HIS998C, ILE1020B, ILE1040B, ILE1040C, ILE970B, ILE970C, ILE984B, ILE984C, ILE999B, ILE999C, LEU1014B, LEU1014C, LEU1019B, LEU1019C, LEU1041B, LEU1041C, LEU1060B, LEU1060C, LEU981B, LEU981C, LYS975B, LYS975C, LYS976B, LYS976C, MET988B, MET988C, PHE1054B, PHE1054C, PHE979B, PHE979C, PRO1008B, PRO1008C, PRO1027B, PRO1027C, PRO1034B, PRO1034C, PRO1053B, PRO1053C, SER1059B, SER1059C, SER995B, SER995C, THR1021B, THR1021C, THR1050B, THR1051B, THR1052B, THR1052C, THR1057B, THR1057C, THR980B, THR980C, THR991B, THR991C, TRP1001B, TRP1001C, TYR977B, TYR977C, TYR987B, TYR987C, TYR994B, TYR994C, VAL1000B, VAL1000C, VAL1003B, VAL1003C, VAL1023B, VAL1028B, VAL1032B, VAL1032C, VAL1036B, VAL1036C, VAL1037B, VAL1037C, VAL1047B, VAL1047C, VAL1049B, VAL1049C, VAL1061B, VAL1061C, VAL986B, VAL986C, VAL996B, VAL996C
• B-D: ARG982D, ARG985D, ASN1056B, ASP992D, GLN1010B, GLN1058B, GLU1005B, GLU1055B, HIS1033D, LEU1060B, PHE1054B, PRO1034D, SER1059B, THR1057B, TYR987D, TYR994D, VAL1032D, VAL1061B
• C-D: ARG982C, ARG985D, GLU1035D, GLU1038C, GLU1038D, HIS1033C, HIS1033D, LEU1041C, LYS975C, LYS976C, LYS976D, PRO1034C, PRO1034D, VAL1032D, VAL1037C, VAL1037D