3PRY

crystal structure of the middle domain of human hsp90-beta refined at 2.3 a resolution

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 86
  • Norm. En. per Res.: -1.8875
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-9.0474	-5.216	-148.06	-162.3233	86	3	0	5635	0	35	36
A-C	0.0	-23.2814	-104.863	-128.1444	72	4	0	4463	0	32	25
B-C	0.0	0.0	-6.5272	-6.5272	18	0	0	629	0	9	7

Interface residues

• A-B: ALA339B, ALA432B, ARG337B, ARG338B, ARG378B, ARG392A, ARG405A, ARG448A, ASN310B, ASN351A, ASN375A, ASN389A, ASN436A, ASP311B, ASP364A, ASP367A, ASP444A, ASP518B, CYS366A, GLN397A, GLN493B, GLN523A, GLN523B, GLN524A, GLU313B, GLU368A, GLU372A, GLU393A, GLU431B, GLU443A, GLU489B, GLU492B, GLU515B, GLU519B, GLY440A, GLY488B, HIS442A, ILE362A, ILE390A, ILE441A, ILE486B, ILE517A, ILE517B, LEU355A, LEU374A, LEU386A, LEU388A, LEU395A, LEU401A, LEU439A, LEU439B, LYS306B, LYS350A, LYS402A, LYS435A, LYS435B, LYS438A, LYS438B, LYS491B, LYS526A, MET363A, MET394A, MET513B, PHE361A, PRO340B, PRO371A, PRO387A, PRO516B, SER307B, SER365A, SER391A, SER398A, SER490B, THR309B, THR487B, THR514B, THR537B, TRP312B, TYR305B, TYR356A, TYR373A, TYR520A, TYR520B, VAL357A, VAL360A, VAL494B
• A-C: ALA339A, ALA432A, ARG337A, ARG338A, ARG378A, ARG392C, ARG405C, ARG448C, ASN310A, ASN375C, ASN389C, ASP311A, ASP364C, ASP367C, ASP518A, CYS366C, CYS521C, GLN397C, GLN493A, GLN523C, GLN524C, GLU313A, GLU368C, GLU372C, GLU431A, GLU443C, GLU489A, GLU492A, GLU515A, GLU519A, GLY488A, HIS442C, ILE362C, ILE370C, ILE390C, ILE517A, ILE517C, LEU355C, LEU369C, LEU388C, LEU401C, LEU439A, LEU439C, LYS306A, LYS402C, LYS435A, LYS435C, LYS438C, LYS491A, LYS526C, MET363C, MET394C, MET513A, PHE341A, PHE361C, PRO340A, PRO371C, PRO516A, PRO516C, SER307A, SER365C, SER391C, SER398C, SER490A, THR309A, THR487A, THR514A, TRP312A, TYR373C, TYR520A, TYR520C, VAL494A
• B-C: ARG337B, ARG392C, ASP314B, GLN298B, GLN396C, GLU299B, GLU300B, GLU303B, GLU313B, GLU393C, GLY302B, LEU395C, LYS306B, LYS399C, MET394C, SER391C, THR297B, TRP312B