3PO3

arrested rna polymerase ii reactivation intermediate

• Total interactions analyzed: 120
• Total true interactions: 32
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 776
  • Norm. En. per Res.: -4.8203
• Hub Node: B(11)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-503.2317	-318.6172	-2918.73	-3740.5788	776	143	62	112493	23	259	237
A-C	-11.2172	7.9631	-78.4355	-81.6896	52	3	0	3180	0	19	19
A-D	-3.2114	-11.2214	-25.6933	-40.1261	28	1	2	1369	1	13	9
A-E	-86.9286	-87.5867	-598.845	-773.3603	207	31	14	23681	7	79	63
A-F	-87.0547	-52.0639	-515.927	-655.0456	175	22	16	21217	5	60	55
A-G	-28.3258	-67.4923	-141.302	-237.1202	62	12	5	5926	4	21	14
A-H	-91.9625	-27.6182	-438.099	-557.6797	142	33	13	17892	5	38	35
A-I	-122.4015	-64.7195	-466.161	-653.282	146	31	10	17610	3	53	44
A-K	-34.1341	-26.9379	-297.651	-358.723	90	16	8	10736	2	23	21
A-S	-64.5922	-90.81	-582.469	-737.8711	272	29	7	24581	8	83	64
B-C	-91.7079	-106.9258	-532.936	-731.5698	166	32	6	18378	9	56	61
B-D	0.0	4.41	-28.8259	-24.4159	33	0	2	1708	0	17	19
B-E	0.0	0.0	-7.2871	-7.2871	5	1	0	260	0	2	1
B-F	0.0	0.0	-9.744	-9.744	20	0	0	422	0	4	6
B-G	0.0	-2.5052	-14.4397	-16.9449	26	2	0	906	0	6	4
B-H	0.0	0.0	-0.1857	-0.1857	2	0	0	35	0	0	0
B-I	-16.8981	-22.5098	-278.155	-317.5629	130	17	3	11595	1	43	45
B-J	-51.8744	-24.2097	-457.937	-534.0211	142	18	7	18804	4	34	36
B-K	-2.8132	-21.9051	-87.581	-112.2993	56	7	0	3514	3	16	19
B-L	-71.1609	-92.9941	-261.156	-425.311	114	11	11	11005	10	45	47
B-S	-13.5835	0.0	-72.688	-86.2715	36	4	2	2940	0	3	3
C-H	0.0	-2.2608	-27.0505	-29.3113	23	1	1	1221	0	8	5
C-J	-27.8778	-69.4307	-267.143	-364.4515	109	20	10	12301	9	39	27
C-K	-51.2195	-29.9875	-548.37	-629.577	153	31	16	23697	5	46	46
C-L	-59.2774	-38.696	-183.284	-281.2574	63	13	9	6459	4	24	17
D-G	-72.9962	-23.5998	-626.655	-723.251	198	31	24	25576	15	56	47
E-F	-7.7344	-23.1475	-27.1635	-58.0454	22	1	0	1190	1	5	5
E-S	0.0	23.9956	-2.4266	21.569	8	0	0	118	0	3	4
F-G	-2.6599	-9.2403	-116.007	-127.9072	52	7	1	4825	1	8	8
H-K	-6.9843	0.0	-36.4582	-43.4425	26	5	0	1693	0	3	4
J-L	0.0	0.0	-8.32	-8.32	10	2	0	445	0	0	1
K-L	0.0	6.1061	-1.1877	4.9184	5	0	0	168	0	3	2

Interface residues

• A-B: ALA1016B, ALA1024B, ALA1068A, ALA1069A, ALA1083B, ALA1105B, ALA1107B, ALA1140B, ALA1143B, ALA1144B, ALA1149A, ALA1154B, ALA1157B, ALA1173B, ALA1199B, ALA1200B, ALA1209B, ALA1412A, ALA1414A, ALA1416A, ALA1434A, ALA1440A, ALA266B, ALA29A, ALA327A, ALA33A, ALA349A, ALA371A, ALA457A, ALA472B, ALA480A, ALA499A, ALA506A, ALA509B, ALA525B, ALA532B, ALA671A, ALA684A, ALA695B, ALA704B, ALA726B, ALA735B, ALA749A, ALA753B, ALA759A, ALA763A, ALA776A, ALA817A, ALA826B, ALA828A, ALA828B, ALA832A, ALA981B, ALA9A, ARG1020B, ARG1067B, ARG1106B, ARG1108B, ARG1116B, ARG1122B, ARG1124B, ARG1129B, ARG1135B, ARG1150B, ARG1159B, ARG1215B, ARG1220B, ARG1222B, ARG12A, ARG1422A, ARG247A, ARG257A, ARG261B, ARG267B, ARG28A, ARG320A, ARG326A, ARG328A, ARG335A, ARG337A, ARG344A, ARG350A, ARG412A, ARG416A, ARG446A, ARG469A, ARG47A, ARG498A, ARG512B, ARG57A, ARG620B, ARG635B, ARG63A, ARG677A, ARG728B, ARG730B, ARG766B, ARG782A, ARG806A, ARG821A, ARG839A, ARG884B, ARG935B, ASN1013B, ASN1074B, ASN1082A, ASN1176B, ASN1178B, ASN1187B, ASN1211B, ASN1265A, ASN1393A, ASN1427A, ASN253A, ASN339A, ASN358A, ASN445A, ASN471A, ASN488A, ASN516B, ASN538B, ASN548A, ASN654A, ASN660A, ASN741A, ASN742A, ASN757A, ASN75A, ASN762B, ASN767B, ASN802A, ASN834B, ASP1049B, ASP1100B, ASP1101B, ASP1125B, ASP1136B, ASP1156B, ASP1186B, ASP1190B, ASP1219B, ASP1223B, ASP1419A, ASP1420A, ASP260A, ASP305A, ASP346A, ASP356A, ASP397B, ASP481A, ASP483A, ASP485A, ASP526A, ASP544A, ASP618B, ASP668A, ASP672A, ASP694B, ASP709B, ASP724B, ASP760B, ASP781A, ASP790A, ASP791A, ASP826A, ASP837B, ASP847A, ASP936B, ASP978B, ASP998B, CYS1029B, CYS1137B, CYS1163B, CYS1166B, CYS1182B, CYS1185B, CYS1400A, CYS1421A, CYS238A, CYS505A, CYS523B, CYS529A, CYS533B, CYS67A, CYS70A, CYS741B, CYS764A, CYS77A, CYS829B, GLN1065B, GLN1070A, GLN1084B, GLN1112B, GLN1117B, GLN1179B, GLN1193B, GLN1205B, GLN1432A, GLN18A, GLN256A, GLN316A, GLN447A, GLN469B, GLN493A, GLN4A, GLN510A, GLN513B, GLN525A, GLN531B, GLN545A, GLN5A, GLN650A, GLN68A, GLN706B, GLN71A, GLN745A, GLN760A, GLN763B, GLN768A, GLN811A, GLN835B, GLN838A, GLN843B, GLN975B, GLN986B, GLU1028B, GLU1053B, GLU1062A, GLU1070B, GLU1120B, GLU1132B, GLU1134B, GLU1149B, GLU1151A, GLU1153B, GLU1206B, GLU1264A, GLU1269A, GLU1403A, GLU1411A, GLU1417A, GLU1426A, GLU16A, GLU254A, GLU25A, GLU262B, GLU26A, GLU312B, GLU319B, GLU333A, GLU433A, GLU486A, GLU495A, GLU496A, GLU500A, GLU526B, GLU529B, GLU542A, GLU621B, GLU681A, GLU696B, GLU697B, GLU698B, GLU699B, GLU72A, GLU742B, GLU76A, GLU771A, GLU795A, GLU801A, GLU812A, GLU822A, GLU833A, GLU836B, GLU846A, GLY1061A, GLY1065A, GLY1068B, GLY1075B, GLY1078B, GLY1109B, GLY1121B, GLY1126B, GLY1127B, GLY1131B, GLY1142B, GLY1164B, GLY1167B, GLY1184B, GLY1395A, GLY1413A, GLY1423A, GLY1431A, GLY1437A, GLY1439A, GLY20A, GLY263B, GLY319A, GLY331A, GLY334A, GLY338A, GLY342A, GLY355A, GLY3A, GLY402B, GLY484A, GLY520B, GLY530A, GLY530B, GLY534B, GLY661A, GLY665A, GLY667A, GLY673A, GLY73A, GLY750A, GLY750B, GLY753A, GLY778A, GLY79A, GLY807A, GLY819A, GLY820A, GLY823A, GLY832B, GLY835A, GLY861A, GLY94A, GLY977B, GLY985B, GLY988B, GLY991B, HIS1015B, HIS1025B, HIS1076B, HIS1097B, HIS1104B, HIS1141B, HIS1161B, HIS1177B, HIS1195B, HIS1258A, HIS400B, HIS451A, HIS490A, HIS515B, HIS518B, HIS659A, HIS734B, HIS740B, HIS744B, HIS761B, HIS786A, HIS80A, HIS816A, HIS887B, HIS92A, ILE1011B, ILE1012B, ILE1017B, ILE1027B, ILE1050B, ILE1055B, ILE1085B, ILE1103B, ILE1139B, ILE1162B, ILE1165B, ILE1172B, ILE1189B, ILE1191B, ILE1194B, ILE1196B, ILE1212B, ILE1408A, ILE1429A, ILE1436A, ILE235A, ILE250A, ILE30A, ILE325A, ILE336A, ILE353A, ILE370A, ILE406A, ILE436A, ILE463A, ILE523A, ILE541A, ILE619B, ILE666A, ILE670A, ILE679A, ILE683A, ILE693B, ILE701B, ILE703B, ILE729B, ILE743B, ILE748B, ILE756A, ILE756B, ILE758A, ILE775A, ILE825A, ILE827B, ILE840B, ILE848A, ILE870B, ILE918B, ILE976B, ILE990B, ILE992B, LEU1026B, LEU1030B, LEU1031B, LEU1059B, LEU1067A, LEU1081A, LEU1081B, LEU1095B, LEU1114B, LEU1128B, LEU1147B, LEU1151B, LEU1168B, LEU1175B, LEU11A, LEU1202B, LEU1203B, LEU1207B, LEU1216B, LEU1268A, LEU1397A, LEU1409A, LEU1418A, LEU1430A, LEU21A, LEU236A, LEU239A, LEU262A, LEU266A, LEU315A, LEU329A, LEU340A, LEU359A, LEU374A, LEU443A, LEU450A, LEU470A, LEU472A, LEU489A, LEU501A, LEU504A, LEU508B, LEU509A, LEU514B, LEU521B, LEU528A, LEU535B, LEU58A, LEU637B, LEU657A, LEU658A, LEU65A, LEU702B, LEU710B, LEU740A, LEU749B, LEU784A, LEU805A, LEU808A, LEU824A, LEU845A, LEU860A, LEU86A, LEU883B, LYS1079B, LYS1080B, LYS1102B, LYS1144A, LYS1148B, LYS1174B, LYS1183B, LYS1201B, LYS1261A, LYS1262A, LYS15A, LYS315B, LYS317A, LYS332A, LYS343A, LYS368A, LYS372A, LYS393B, LYS403A, LYS403B, LYS452A, LYS470B, LYS471B, LYS507B, LYS510B, LYS533A, LYS537B, LYS569A, LYS687A, LYS727B, LYS744A, LYS752A, LYS789A, LYS830A, LYS843A, LYS886B, LYS934B, LYS979B, LYS987B, MET1021B, MET1063A, MET1072B, MET1082B, MET1098B, MET1111B, MET1133B, MET1138B, MET1152B, MET1169B, MET1208B, MET1210B, MET1398A, MET1433A, MET234A, MET304A, MET341A, MET453A, MET455A, MET456A, MET473B, MET487A, MET676A, MET705B, MET746A, MET747B, MET74A, MET761A, MET818A, MET839B, MET849A, MET999B, PHE1047B, PHE1069B, PHE1084A, PHE1086B, PHE1087B, PHE1130B, PHE1146B, PHE1158B, PHE1180B, PHE1204B, PHE1224B, PHE1402A, PHE1410A, PHE1441A, PHE19A, PHE228A, PHE22A, PHE252A, PHE347A, PHE401B, PHE444A, PHE468A, PHE482A, PHE540A, PHE655A, PHE662A, PHE738B, PHE758B, PHE777A, PHE779A, PHE787A, PHE813A, PHE814A, PHE815A, PHE81A, PHE95A, PHE980B, PRO1000B, PRO1014B, PRO1018B, PRO1046B, PRO10A, PRO1110B, PRO1118B, PRO1197B, PRO1214B, PRO1435A, PRO240A, PRO242A, PRO243A, PRO244A, PRO245A, PRO248A, PRO24A, PRO316B, PRO321A, PRO357A, PRO367A, PRO377A, PRO441A, PRO448A, PRO464A, PRO492A, PRO511B, PRO514A, PRO524B, PRO528B, PRO725B, PRO745B, PRO759B, PRO765B, PRO785A, PRO78A, PRO794A, PRO810A, SER1019B, SER1056B, SER1066B, SER1145B, SER1155B, SER1221B, SER1401A, SER1415A, SER1425A, SER229A, SER23A, SER249A, SER251A, SER255A, SER264B, SER265B, SER318A, SER31A, SER324A, SER348A, SER354A, SER369A, SER449A, SER454A, SER466A, SER473A, SER476A, SER494A, SER540B, SER60A, SER663A, SER700B, SER732B, SER746B, SER751A, SER754A, SER762A, SER764B, SER769A, SER788A, SER793A, SER796A, SER7A, SER803A, SER831B, SER838B, SER859A, SER8A, SER919B, THR1022B, THR1048B, THR1051B, THR1077A, THR1077B, THR1115B, THR1170B, THR1213B, THR1218B, THR1266A, THR1394A, THR13A, THR1405A, THR1438A, THR237A, THR351A, THR373A, THR375A, THR467A, THR475A, THR497A, THR517B, THR527A, THR527B, THR539A, THR664A, THR669A, THR680A, THR69A, THR737B, THR739B, THR768B, THR783A, THR809A, THR827A, THR831A, THR834A, THR882B, THR916B, THR989B, THR993B, TRP233A, TRP308B, TRP519B, TRP552A, TRP656A, TYR1192B, TYR1198B, TYR1217B, TYR303A, TYR376A, TYR404A, TYR417A, TYR465A, TYR478A, TYR6A, TYR769B, TYR804A, TYR830B, TYR833B, TYR836A, TYR866B, TYR994B, VAL1023B, VAL1052B, VAL1064A, VAL1066A, VAL1099B, VAL1113B, VAL1119B, VAL1160B, VAL1171B, VAL1406A, VAL1424A, VAL1428A, VAL14A, VAL17A, VAL227A, VAL241A, VAL246A, VAL27A, VAL2A, VAL300A, VAL32A, VAL345A, VAL352A, VAL366A, VAL442A, VAL491A, VAL507A, VAL522B, VAL524A, VAL536B, VAL723B, VAL731B, VAL743A, VAL747A, VAL765A, VAL770A, VAL780A, VAL800A, VAL829A, VAL842A, VAL93A
• A-C: ALA223C, ALA671A, ASN31C, ASN660A, ASN736A, ASN741A, ASN742A, ASP190C, ASP196C, ASP220C, ASP538A, ASP544A, ASP668A, ASP672A, GLN195C, GLN224C, GLN745A, GLU194C, GLU200C, GLU542A, GLY665A, GLY667A, GLY673A, HIS188C, HIS659A, ILE666A, ILE670A, LEU186C, LEU571A, LEU737A, LEU740A, LYS222C, LYS533A, LYS567A, LYS569A, LYS738A, PHE219C, PHE662A, PRO568A, PRO570A, PRO674A, SER197C, SER663A, THR189C, THR664A, THR669A, THR675A, TRP192C, TYR191C, TYR193C, TYR221C, VAL743A
• A-D: ALA9A, ARG12A, ARG13D, ARG14D, ARG230A, ASN225A, GLN18A, GLU16A, GLU226A, GLU26A, GLY20A, ILE30A, LEU1418A, LEU15D, LEU21A, LYS16D, LYS17D, LYS76D, MET1454A, PHE228A, PHE22A, PRO10A, SER23A, SER4D, SER6D, SER8A, TRP233A, VAL227A
• A-E: ALA1010A, ALA1014A, ALA127A, ALA1343A, ALA1346A, ALA1347A, ALA1369A, ALA138E, ALA139E, ALA15E, ALA181E, ALA185E, ALA209E, ARG1012A, ARG1023A, ARG11E, ARG1215A, ARG1274A, ARG1289A, ARG1326A, ARG1345A, ARG1366A, ARG1422A, ARG14E, ARG162E, ARG167E, ARG169E, ARG177E, ARG180E, ARG192E, ARG200E, ARG207E, ARG212E, ARG7E, ARG857A, ARG944A, ASN1004A, ASN1009A, ASN1364A, ASN1393A, ASN143E, ASN854A, ASN858A, ASN862A, ASP1013A, ASP130A, ASP1323A, ASP1334A, ASP1373A, ASP159E, ASP182E, ASP853A, ASP871A, ASP939A, CYS1019A, CYS1020A, GLN1008A, GLN1011A, GLN1211A, GLN1218A, GLN1378A, GLN174E, GLN179E, GLN3E, GLN865A, GLN935A, GLU1005A, GLU1121A, GLU120A, GLU1315A, GLU1337A, GLU1342A, GLU137E, GLU148E, GLU160E, GLU163E, GLU172E, GLU203E, GLU4E, GLU870A, GLU945A, GLY1002A, GLY1321A, GLY1340A, GLY1344A, GLY1379A, GLY1380A, GLY206E, GLY861A, GLY869A, GLY872A, HIS146E, HIS147E, HIS153E, ILE1006A, ILE1007A, ILE128A, ILE1322A, ILE1327A, ILE1335A, ILE1341A, ILE144E, ILE178E, ILE198E, ILE199E, ILE213E, ILE864A, ILE867A, ILE878A, LEU1000A, LEU1017A, LEU1313A, LEU1339A, LEU1348A, LEU1381A, LEU140E, LEU149E, LEU156E, LEU164E, LEU165E, LEU170E, LEU175E, LEU186E, LEU860A, LEU883A, LEU943A, LEU956A, LYS1003A, LYS122E, LYS129A, LYS133A, LYS1350A, LYS152E, LYS161E, LYS166E, LYS171E, LYS197E, LYS201E, LYS938A, LYS941A, MET1317A, MET1336A, MET1368A, MET1375A, MET215E, MET873A, PHE1018A, PHE1332A, PHE866A, PHE942A, PHE947A, PRO125E, PRO1320A, PRO1324A, PRO151E, PRO158A, PRO176E, PRO183E, PRO955A, PRO957A, SER10E, SER1314A, SER1392A, SER173E, SER202E, SER205E, SER210E, SER859A, THR1016A, THR1117A, THR1318A, THR1325A, THR1329A, THR1376A, THR1377A, THR1382A, THR145E, THR204E, THR855A, THR856A, TRP954A, TYR1119A, TYR1328A, TYR1349A, TYR1353A, TYR1362A, TYR1365A, TYR168E, TYR208E, TYR211E, TYR868A, VAL1015A, VAL1316A, VAL1319A, VAL1338A, VAL1372A, VAL1374A, VAL141E, VAL142E, VAL150E, VAL184E, VAL195E, VAL196E, VAL863A, VAL946A, VAL948A, VAL999A
• A-F: ALA1051A, ALA105F, ALA121F, ALA1434A, ALA1440A, ALA499A, ALA80F, ALA876A, ALA91F, ALA98F, ARG1001A, ARG1055A, ARG119F, ARG135F, ARG136F, ARG1422A, ARG387A, ARG498A, ARG635A, ARG79F, ARG857A, ARG90F, ARG92F, ARG97F, ASN1004A, ASN104F, ASN384A, ASN439A, ASN854A, ASN858A, ASN862A, ASP116F, ASP140F, ASP1442A, ASP1446A, ASP145F, ASP154F, ASP77F, ASP853A, ASP874A, CYS505A, GLN100F, GLN1052A, GLN427A, GLN493A, GLN503A, GLN510A, GLN640A, GLN78F, GLU1050A, GLU1062A, GLU114F, GLU124F, GLU127F, GLU1447A, GLU1448A, GLU144F, GLU149F, GLU150F, GLU378A, GLU495A, GLU496A, GLU500A, GLU89F, GLY1002A, GLY1061A, GLY113F, GLY141F, GLY1437A, GLY1439A, GLY429A, GLY638A, GLY861A, GLY95F, HIS1059A, HIS851A, HIS877A, ILE1007A, ILE101F, ILE120F, ILE130F, ILE134F, ILE1436A, ILE1445A, ILE152F, ILE385A, ILE93F, LEU1000A, LEU1054A, LEU1067A, LEU111F, LEU118F, LEU125F, LEU132F, LEU138F, LEU1450A, LEU151F, LEU155F, LEU501A, LEU504A, LEU509A, LEU860A, LEU94F, LEU998A, LEU99F, LYS1003A, LYS128F, LYS129F, LYS1452A, LYS431A, LYS452A, LYS87F, MET103F, MET1063A, MET122F, MET1433A, MET1444A, MET1454A, MET849A, MET85F, PHE108F, PHE143F, PHE1441A, PRO1060A, PRO106F, PRO117F, PRO131F, PRO139F, PRO1435A, PRO1455A, PRO382A, PRO441A, PRO514A, PRO639A, PRO83F, SER102F, SER142F, SER1449A, SER147F, SER494A, SER502A, THR115F, THR1438A, THR381A, THR497A, THR81F, THR82F, THR855A, THR856A, THR86F, THR96F, TRP146F, TRP430A, TYR137F, TYR1453A, TYR376A, TYR383A, TYR428A, TYR84F, TYR852A, TYR88F, VAL1057A, VAL1058A, VAL1064A, VAL107F, VAL109F, VAL133F, VAL1443A, VAL1451A, VAL148F, VAL379A, VAL380A, VAL850A, VAL863A, VAL999A
• A-G: ALA68G, ARG12A, ARG21G, ARG58G, ARG60G, ASN10G, ASN71G, ASP1442A, ASP1446A, ASP65G, GLN1432A, GLN24G, GLN57G, GLU1447A, GLU1448A, GLU495A, GLU496A, GLU69G, GLY1431A, GLY1439A, GLY19G, GLY429A, GLY59G, GLY66G, HIS14G, ILE1445A, ILE56G, ILE61G, LEU11A, LEU13G, LEU1450A, LEU26G, LEU62G, LEU9G, LYS1452A, LYS15A, LYS23G, MET1433A, MET1444A, MET1454A, MET22G, PHE1441A, PHE17G, PHE18G, PHE70G, PRO10A, PRO1455A, PRO15G, PRO20G, PRO63G, SER1449A, SER494A, SER67G, THR12G, THR13A, THR497A, THR64G, TYR1453A, VAL1443A, VAL1451A, VAL2A, VAL379A
• A-H: ALA101H, ALA140H, ALA564A, ARG1036A, ARG124H, ARG19H, ARG25H, ARG532A, ARG537A, ARG77H, ARG80H, ASN21H, ASN43H, ASN603A, ASN736A, ASN741A, ASP16H, ASP41H, ASP538A, ASP557A, ASP602A, ASP609A, ASP739A, ASP91H, ASP94H, ASP974A, CYS24H, GLN137H, GLN576A, GLN589A, GLN611A, GLN83H, GLN968A, GLU105H, GLU106H, GLU138H, GLU27H, GLU45H, GLU734A, GLY119H, GLY120H, GLY18H, GLY558A, GLY574A, GLY615A, GLY99H, HIS972A, HIS975A, ILE112H, ILE144H, ILE26H, ILE42H, ILE560A, ILE565A, ILE566A, ILE577A, ILE608A, ILE612A, ILE613A, ILE973A, LEU121H, LEU122H, LEU125H, LEU132H, LEU142H, LEU143H, LEU38H, LEU40H, LEU46H, LEU536A, LEU543A, LEU547A, LEU550A, LEU571A, LEU597A, LEU598A, LEU606A, LEU63H, LEU737A, LEU740A, LEU89H, LYS103H, LYS136H, LYS22H, LYS37H, LYS567A, LYS569A, LYS575A, LYS601A, LYS738A, LYS744A, LYS977A, MET123H, MET748A, MET97H, PHE104H, PHE118H, PHE47H, PHE540A, PHE591A, PHE614A, PRO17H, PRO48H, PRO561A, PRO563A, PRO568A, PRO570A, PRO600A, PRO81H, PRO82H, SER117H, SER573A, SER579A, SER599A, SER78H, THR100H, THR39H, THR535A, THR539A, THR562A, THR596A, THR76H, THR976A, TRP556A, TRP572A, TRP79H, TYR102H, TYR115H, TYR116H, TYR141H, TYR20H, TYR93H, TYR95H, TYR98H, VAL114H, VAL23H, VAL44H, VAL546A, VAL559A, VAL616A, VAL735A, VAL96H
• A-I: ALA1090A, ALA1149A, ALA1200A, ALA1201A, ALA38I, ALA697A, ALA699A, ALA704A, ARG118I, ARG1194A, ARG17I, ARG24I, ARG30I, ARG45I, ARG70I, ARG711A, ARG73I, ARG782A, ARG91I, ARG92I, ASN116I, ASN1265A, ASN22I, ASN23I, ASN51I, ASN700A, ASP113I, ASP1155A, ASP1157A, ASP1198A, ASP1257A, ASP19I, ASP65I, ASP716A, ASP781A, ASP790A, ASP791A, ASP94I, GLN114I, GLN698A, GLN87I, GLN89I, GLN90I, GLU1151A, GLU1196A, GLU1255A, GLU1256A, GLU1264A, GLU1269A, GLU18I, GLU21I, GLU47I, GLU696A, GLU712A, GLU715A, GLY1088A, GLY39I, HIS1258A, HIS46I, ILE1148A, ILE1152A, ILE1163A, ILE49I, ILE62I, LEU1143A, LEU1192A, LEU1193A, LEU1195A, LEU1197A, LEU1260A, LEU1268A, LEU25I, LEU26I, LEU42I, LEU48I, LEU68I, LEU701A, LEU702A, LEU710A, LEU784A, LEU99I, LYS1093A, LYS1144A, LYS115I, LYS1235A, LYS1261A, LYS20I, LYS695A, LYS773A, LYS789A, LYS797A, LYS93I, MET13I, MET708A, MET97I, PHE100I, PHE101I, PHE27I, PHE714A, PHE777A, PHE779A, PHE787A, PHE85I, PHE86I, PRO1156A, PRO1158A, PRO1164A, PRO1190A, PRO16I, PRO41I, PRO66I, PRO69I, PRO785A, SER112I, SER1145A, SER1150A, SER1189A, SER40I, SER713A, SER71I, SER788A, SER88I, SER96I, THR111I, THR1147A, THR2I, THR50I, THR67I, THR694A, THR703A, THR709A, THR95I, TRP1191A, TYR1153A, TYR1154A, TYR15I, TYR44I, TYR792A, VAL1146A, VAL1162A, VAL43I, VAL693A, VAL718A, VAL780A, VAL84I, VAL98I
• A-K: ALA27K, ALA30K, ALA371A, ALA3K, ALA48K, ALA59K, ALA60K, ARG469A, ARG47K, ARG6K, ARG70K, ARG74K, ASN2K, ASN358A, ASN44K, ASN548A, ASP24K, ASP356A, ASP544A, ASP555A, ASP557A, ASP5K, GLN545A, GLN76K, GLU360A, GLU542A, GLU64K, GLU8K, GLY355A, GLY365A, GLY558A, HIS40K, HIS659A, HIS65K, ILE33K, ILE370A, ILE463A, ILE560A, ILE75K, LEU359A, LEU51K, LEU543A, LEU547A, LEU550A, LEU57K, LEU658A, LEU73K, LEU9K, LYS26K, LYS368A, LYS372A, LYS461A, LYS62K, LYS651A, LYS72K, MET1K, MET549A, PHE58K, PHE655A, PHE67K, PHE68K, PHE71K, PRO28K, PRO357A, PRO367A, PRO464A, PRO4K, PRO554A, PRO561A, PRO66K, SER354A, SER369A, SER466A, THR34K, THR351A, THR467A, TRP552A, TRP556A, TYR465A, TYR551A, TYR61K, VAL31K, VAL32K, VAL366A, VAL462A, VAL546A, VAL553A, VAL559A, VAL56K, VAL63K
• A-S: ALA1076A, ALA1087A, ALA1090A, ALA1131A, ALA1200A, ALA1201A, ALA1357A, ALA155S, ALA197S, ALA233S, ALA237S, ALA249S, ALA256S, ALA259S, ALA289S, ALA290S, ALA291S, ALA301S, ALA480A, ALA704A, ALA725A, ALA759A, ALA828A, ALA952A, ARG1135A, ARG1199A, ARG1281A, ARG149S, ARG198S, ARG200S, ARG263S, ARG268S, ARG287S, ARG305S, ARG446A, ARG590A, ARG720A, ARG726A, ARG731A, ARG821A, ASN1082A, ASN1203A, ASN1232A, ASN1354A, ASN205S, ASN210S, ASN211S, ASN252S, ASN255S, ASN304S, ASN479A, ASN717A, ASN723A, ASN757A, ASN953A, ASP1198A, ASP1204A, ASP1206A, ASP1231A, ASP1233A, ASP1359A, ASP150S, ASP158S, ASP232S, ASP235S, ASP267S, ASP481A, ASP483A, ASP485A, ASP592A, ASP716A, ASP727A, ASP826A, CYS271S, CYS274S, CYS297S, CYS302S, GLN1078A, GLN1128A, GLN1130A, GLN1171A, GLN1211A, GLN151S, GLN251S, GLN257S, GLN283S, GLN285S, GLN760A, GLN768A, GLU1074A, GLU1129A, GLU1139A, GLU1165A, GLU1167A, GLU1168A, GLU1214A, GLU1230A, GLU1234A, GLU1307A, GLU246S, GLU262S, GLU276S, GLU593A, GLU712A, GLU715A, GLU724A, GLU734A, GLU822A, GLU951A, GLY1088A, GLY1210A, GLY1213A, GLY1360A, GLY258S, GLY272S, GLY303S, GLY594A, GLY604A, GLY707A, GLY730A, GLY753A, GLY766A, GLY819A, GLY820A, GLY823A, GLY950A, HIS1085A, HIS1173A, HIS706A, HIS816A, ILE1169A, ILE1170A, ILE1227A, ILE1356A, ILE201S, ILE202S, ILE207S, ILE245S, ILE248S, ILE261S, ILE756A, ILE758A, ILE825A, LEU1081A, LEU1133A, LEU1172A, LEU1176A, LEU1207A, LEU1236A, LEU1306A, LEU148S, LEU153S, LEU236S, LEU241S, LEU253S, LEU284S, LEU293S, LEU702A, LEU710A, LEU722A, LEU732A, LEU824A, LYS1092A, LYS1093A, LYS1132A, LYS1205A, LYS1217A, LYS1235A, LYS1286A, LYS1290A, LYS1300A, LYS147S, LYS154S, LYS162S, LYS184S, LYS196S, LYS209S, LYS215S, LYS234S, LYS242S, LYS244S, LYS250S, LYS273S, LYS275S, LYS277S, LYS278S, LYS307S, LYS601A, LYS619A, LYS620A, LYS705A, LYS728A, LYS744A, LYS752A, LYS830A, LYS880A, MET1079A, MET1202A, MET1209A, MET1284A, MET1285A, MET708A, PHE1084A, PHE1086A, PHE1174A, PHE269S, PHE296S, PHE308S, PHE591A, PHE721A, PHE755A, PRO1075A, PRO238S, PRO240S, PRO292S, SER1091A, SER1136A, SER1175A, SER1229A, SER1358A, SER1361A, SER204S, SER208S, SER264S, SER280S, SER288S, SER309S, SER713A, SER751A, SER754A, SER769A, SER882A, THR1077A, THR1080A, THR1083A, THR1208A, THR260S, THR266S, THR270S, THR286S, THR294S, THR295S, THR298S, THR595A, THR703A, THR827A, TRP1228A, TRP1304A, TRP306S, TYR1362A, TYR195S, TYR199S, TYR203S, TYR254S, TYR281S, TYR282S, TYR804A, VAL1089A, VAL1094A, VAL1226A, VAL1282A, VAL1283A, VAL1305A, VAL152S, VAL159S, VAL206S, VAL265S, VAL718A, VAL719A, VAL735A, VAL747A, VAL765A
• B-C: ALA1003B, ALA1083B, ALA164C, ALA168C, ALA173C, ALA174C, ALA175C, ALA198C, ALA225C, ALA28C, ALA30C, ALA39C, ALA59C, ALA64C, ARG1060B, ARG1067B, ARG148C, ARG34C, ARG35C, ARG66C, ARG848B, ARG852B, ARG904B, ARG969B, ARG995B, ARG996B, ASN1074B, ASN184C, ASN206C, ASN231C, ASN31C, ASN54C, ASN786B, ASN842B, ASP181C, ASP190C, ASP60C, ASP847B, ASP950B, ASP998B, GLN1065B, GLN1084B, GLN195C, GLN203C, GLN224C, GLN843B, GLU1004B, GLU1053B, GLU1070B, GLU166C, GLU177C, GLU179C, GLU194C, GLU200C, GLU210C, GLU233C, GLU40C, GLU50C, GLU61C, GLU997B, GLY1005B, GLY1063B, GLY1068B, GLY1075B, GLY1078B, GLY171C, GLY849B, GLY902B, GLY947B, HIS1062B, HIS1076B, HIS167C, HIS188C, HIS65C, ILE1006B, ILE1085B, ILE144C, ILE163C, ILE176C, ILE38C, ILE63C, ILE795B, ILE846B, ILE948B, ILE973B, LEU1059B, LEU1081B, LEU186C, LEU27C, LEU58C, LEU69C, LEU796B, LEU850B, LEU854B, LYS1033B, LYS1079B, LYS1080B, LYS149C, LYS165C, LYS169C, LYS185C, LYS187C, LYS191B, LYS199C, LYS972B, MET1072B, MET1082B, MET230C, MET29C, MET37C, MET999B, PHE1001B, PHE1069B, PHE1086B, PHE178C, PHE228C, PHE62C, PHE855B, PHE856B, PRO1000B, PRO172C, PRO182C, PRO202C, PRO799B, PRO901B, SER1056B, SER1066B, SER197C, SER204C, SER32C, SER844B, SER845B, SER853B, THR1002B, THR1077B, THR189C, THR56C, THR783B, THR970B, THR971B, TRP170C, TRP183C, TRP192C, TRP201C, TYR1064B, TYR1073B, TYR180C, TYR190B, TYR191C, TYR193C, TYR229C, TYR785B, TYR797B, TYR798B, TYR830B, TYR994B, VAL1007B, VAL1071B, VAL232C, VAL235C, VAL36C, VAL49C, VAL51C, VAL57C, VAL903B, VAL949B
• B-D: ARG11D, ARG1215B, ARG1220B, ARG1222B, ARG12D, ARG13D, ARG14D, ASN1187B, ASP1186B, ASP1190B, ASP1219B, ASP1223B, CYS1166B, CYS1185B, GLU20D, GLY1164B, GLY1167B, GLY1184B, ILE1165B, ILE1189B, ILE1191B, LEU1168B, LEU15D, LYS16D, LYS17D, SER1221B, SER4D, SER6D, THR10D, THR1213B, TYR1192B, TYR1217B, VAL18D
• B-E: ARG1222B, ASP1223B, GLN174E, LYS171E, PHE1224B
• B-F: ALA1140B, ALA1143B, ALA1144B, ALA91F, ARG92F, ASP1223B, ASP140F, GLY1142B, GLY141F, GLY95F, HIS1141B, ILE1139B, LEU99F, LYS87F, MET1138B, PHE1224B, PRO139F, SER1145B, THR96F, TYR88F
• B-G: ALA1144B, ARG1150B, ASN10G, ASN1178B, ASP1190B, ASP65G, GLN1179B, GLU1149B, GLU1153B, GLY40G, HIS1177B, HIS1195B, ILE1189B, LEU62G, LYS1148B, LYS1188B, LYS41G, MET1152B, PHE1146B, PRO63G, SER1145B, SER152G, THR39G, THR64G, TYR1192B, VAL154G
• B-H: LYS22H, MET1082B
• B-I: ALA266B, ALA56I, ALA594B, ALA735B, ARG267B, ARG287B, ARG30I, ARG392B, ARG45I, ARG595B, ARG5I, ARG601B, ARG617B, ARG620B, ARG70I, ARG91I, ARG92I, ASN11I, ASN12I, ASN306B, ASN592B, ASP294B, ASP307B, ASP320B, ASP391B, ASP394B, ASP576B, ASP618B, ASP61I, ASP65I, ASP94I, ASP9I, CYS10I, CYS29I, CYS302B, CYS32I, CYS7I, GLN309B, GLN325B, GLN60I, GLN87I, GLN89I, GLN90I, GLU262B, GLU296B, GLU299B, GLU312B, GLU319B, GLU47I, GLU621B, GLU623B, GLU697B, GLU698B, GLU699B, GLY263B, GLY295B, GLY321B, GLY57I, GLY63I, HIS46I, HIS734B, HIS740B, ILE292B, ILE297B, ILE324B, ILE52I, ILE619B, ILE62I, ILE701B, ILE703B, LEU104I, LEU14I, LEU298B, LEU311B, LEU314B, LEU387B, LEU390B, LEU42I, LEU48I, LEU68I, LEU702B, LYS227B, LYS315B, LYS393B, LYS622B, LYS649B, LYS93I, MET13I, MET310B, MET313B, MET597B, PHE100I, PHE27I, PHE322B, PHE4I, PHE6I, PHE738B, PHE85I, PHE86I, PRO16I, PRO293B, PRO316B, PRO593B, PRO66I, PRO69I, SER265B, SER64I, SER700B, SER88I, THR2I, THR31I, THR3I, THR50I, THR55I, THR578B, THR67I, THR736B, THR737B, THR739B, TRP308B, TYR15I, TYR44I, VAL102I, VAL283B, VAL305B, VAL318B, VAL43I, VAL58I, VAL59I, VAL84I
• B-J: ALA1003B, ALA1035B, ALA1036B, ALA35J, ALA819B, ALA823B, ARG43J, ARG47J, ARG48J, ARG62J, ARG6J, ARG815B, ARG848B, ARG852B, ARG996B, ASN1040B, ASN64J, ASN784B, ASN786B, ASN822B, ASN842B, ASP1009B, ASP188B, ASP198B, ASP31J, ASP55J, ASP847B, CYS1029B, CYS10J, CYS195B, CYS45J, CYS46J, CYS7J, GLN115B, GLN800B, GLN821B, GLN951B, GLU1004B, GLU1041B, GLU1070B, GLU186B, GLU194B, GLU32J, GLU58J, GLU816B, GLY1005B, GLY1039B, GLY1042B, GLY1068B, GLY1088B, GLY11J, GLY33J, GLY779B, GLY804B, GLY820B, GLY849B, HIS1062B, HIS53J, ILE1006B, ILE2J, ILE50J, ILE57J, ILE795B, ILE824B, ILE846B, LEU1010B, LEU1037B, LEU1059B, LEU189B, LEU192B, LEU25J, LEU36J, LEU41J, LEU51J, LEU56J, LEU61J, LEU782B, LEU796B, LEU803B, LEU817B, LEU850B, LEU854B, LYS1033B, LYS12J, LYS191B, LYS193B, LYS42J, LYS59J, LYS801B, LYS813B, MET1072B, MET1J, MET49J, PHE1087B, PHE197B, PHE60J, PHE814B, PHE851B, PHE856B, PHE8J, PRO1008B, PRO1089B, PRO196B, PRO4J, PRO65J, PRO799B, PRO802B, PRO818B, SER1032B, SER1038B, SER187B, SER37J, SER844B, SER845B, SER9J, THR1002B, THR1090B, THR185B, THR34J, THR52J, THR783B, THR805B, TRP18J, TYR1064B, TYR1091B, TYR190B, TYR21J, TYR44J, TYR63J, TYR785B, TYR797B, TYR798B, VAL1007B, VAL1034B, VAL13J, VAL14J, VAL3J, VAL54J, VAL5J, VAL780B, VAL787B, VAL825B
• B-K: ALA3K, ALA69K, ARG1122B, ARG47K, ARG6K, ARG848B, ARG852B, ARG995B, ARG996B, ASN1074B, ASN2K, ASN44K, ASN842B, ASN946B, ASP1100B, ASP1101B, ASP39K, ASP847B, ASP998B, GLN843B, GLN975B, GLU64K, GLU997B, GLY1075B, GLY1078B, GLY991B, HIS1076B, HIS1104B, HIS40K, HIS65K, ILE1103B, ILE846B, ILE976B, ILE992B, LEU45K, LEU9K, LYS1079B, LYS1102B, MET1K, PHE10K, PHE67K, PHE68K, PRO4K, PRO66K, SER831B, SER844B, SER845B, THR1077B, THR41K, THR944B, THR993B, TYR61K, TYR833B, TYR994B, VAL1099B, VAL63K
• B-L: ALA111B, ALA32L, ALA45L, ALA59L, ALA69L, ALA900B, ARG120B, ARG42L, ARG47L, ARG54L, ARG60L, ARG63L, ARG70L, ARG848B, ARG852B, ARG904B, ARG967B, ARG969B, ASN786B, ASN957B, ASP106B, ASP44L, ASP847B, ASP891B, ASP894B, ASP895B, ASP896B, ASP950B, CYS31L, CYS34L, CYS51L, GLN115B, GLN66L, GLN843B, GLN951B, GLN958B, GLU104B, GLU116B, GLU33L, GLU68L, GLU863B, GLU872B, GLU875B, GLY107B, GLY52L, GLY849B, GLY897B, GLY902B, GLY913B, GLY947B, GLY960B, HIS110B, HIS53L, ILE30L, ILE55L, ILE846B, ILE899B, ILE911B, ILE948B, ILE973B, LEU112B, LEU119B, LEU122B, LEU192B, LEU27L, LEU40L, LEU56L, LEU57L, LEU64L, LEU893B, LEU898B, LEU953B, LEU961B, LYS191B, LYS193B, LYS28L, LYS58L, LYS62L, LYS876B, LYS892B, LYS934B, LYS962B, LYS965B, MET789B, PHE67L, PHE874B, PHE963B, PRO901B, SER105B, SER41L, THR109B, THR43L, THR61L, THR873B, THR915B, THR955B, THR956B, THR970B, THR971B, TYR113B, TYR29L, TYR797B, VAL102B, VAL108B, VAL46L, VAL65L, VAL787B, VAL903B, VAL905B, VAL949B, VAL952B, VAL954B, VAL964B, VAL966B
• B-S: ALA1016B, ALA289S, ALA290S, ALA291S, ALA772B, ARG1020B, ARG287S, ARG766B, ASN767B, ASP837B, CYS533B, GLN283S, GLN285S, GLN763B, GLN770B, GLN986B, GLU529B, GLU836B, GLY530B, GLY985B, HIS1015B, HIS984B, LEU293S, LYS987B, MET1021B, MET773B, PRO1018B, PRO292S, PRO765B, SER1019B, SER288S, SER309S, SER764B, THR294S, THR768B, TYR769B
• C-H: ASN184C, ASN21H, ASN43H, ASP190C, ASP217C, ASP220C, ASP94H, GLU45H, HIS188C, LEU186C, LEU46H, LYS187C, LYS222C, LYS22H, PHE219C, PHE47H, PRO218C, PRO48H, THR189C, TYR193C, TYR221C, TYR95H, VAL44H
• C-J: ALA164C, ALA168C, ALA173C, ALA174C, ALA175C, ALA45C, ALA59C, ARG148C, ARG43J, ARG62J, ARG66C, ARG6J, ASN112C, ASN140C, ASN17C, ASN231C, ASN64J, ASP136C, ASP16C, ASP16J, ASP55J, CYS10J, CYS145C, CYS45J, CYS46J, CYS7J, GLN135C, GLN151C, GLU138C, GLU152C, GLU177C, GLU19J, GLU233C, GLU58J, GLY11J, GLY139C, GLY141C, GLY150C, GLY15J, GLY171C, GLY236C, GLY40J, GLY68C, HIS167C, HIS53J, HIS65C, ILE133C, ILE134C, ILE144C, ILE176C, ILE238C, ILE2J, ILE38C, ILE46C, ILE57J, ILE63C, ILE70C, LEU143C, LEU147C, LEU22J, LEU39J, LEU41J, LEU44C, LEU56J, LEU58C, LEU61J, LEU67C, LEU69C, LEU72C, LYS12J, LYS137C, LYS146C, LYS149C, LYS169C, LYS17J, LYS205C, LYS42J, LYS59J, MET1J, PHE60J, PHE62C, PHE8J, PRO172C, PRO4J, PRO65J, PRO71C, SER115C, SER20J, SER234C, SER237C, SER9J, THR110C, THR111C, THR43C, THR55C, THR56C, TRP170C, TRP18J, TYR114C, TYR63J, VAL113C, VAL13J, VAL142C, VAL14J, VAL232C, VAL235C, VAL3J, VAL57C, VAL5J
• C-K: ALA100K, ALA13C, ALA164C, ALA168C, ALA256C, ALA261C, ALA28C, ALA30C, ALA39C, ALA48K, ALA69K, ALA86K, ALA90K, ARG11C, ARG246C, ARG34C, ARG35C, ARG47K, ARG6K, ARG84C, ASN104K, ASN110K, ASN17C, ASN24C, ASN31C, ASN44K, ASN52K, ASN89K, ASN92K, ASN96K, ASP16C, ASP19C, ASP241C, ASP249C, ASP266C, ASP268C, ASP26C, ASP39K, ASP5K, ASP82K, ASP85C, ASP85K, CYS91K, GLN112K, GLN224C, GLN242C, GLN252C, GLN264C, GLN267C, GLN7C, GLU106K, GLU108K, GLU12C, GLU166C, GLU36K, GLU38K, GLU3C, GLU40C, GLU49K, GLU4C, GLU8K, GLY162C, GLY247C, GLY43K, GLY5C, GLY99K, HIS167C, HIS40K, ILE10C, ILE163C, ILE21C, ILE21K, ILE248C, ILE258C, ILE33K, ILE46K, ILE75K, ILE94K, ILE95K, LEU101K, LEU111K, LEU114K, LEU11K, LEU12K, LEU19K, LEU22C, LEU251C, LEU259C, LEU260C, LEU262C, LEU27C, LEU33C, LEU42K, LEU45K, LEU51K, LEU73K, LEU87K, LEU98K, LEU9K, LYS102K, LYS15C, LYS165C, LYS169C, LYS18K, LYS20K, LYS253C, LYS254C, LYS37K, LYS84K, LYS88K, LYS97K, LYS9C, MET230C, MET265C, MET29C, MET37C, PHE105K, PHE10K, PHE20C, PHE35K, PHE71K, PHE7K, PRO239C, PRO6C, PRO83K, SER14C, SER17K, SER23C, SER257C, SER32C, SER93K, THR103K, THR107K, THR113K, THR250C, THR263C, THR41K, TRP109K, TRP170C, TYR61K, TYR82C, VAL18C, VAL232C, VAL240C, VAL243C, VAL244C, VAL245C, VAL255C, VAL25C, VAL31K, VAL36C, VAL63K, VAL8C
• C-L: ALA159C, ALA168C, ALA45C, ALA59C, ALA59L, ALA64C, ALA69L, ARG60L, ARG63L, ARG66C, ARG70L, ARG84C, ASN54C, ASP47C, ASP60C, ASP90C, CYS157C, CYS34L, GLN66L, GLU166C, GLU33L, GLU50C, GLU52C, GLU61C, GLU68L, GLY150C, GLY162C, GLY68C, HIS167C, HIS65C, HIS91C, ILE163C, ILE30L, ILE46C, ILE63C, ILE70C, LEU153C, LEU155C, LEU64L, LEU67C, LEU69C, LYS149C, LYS154C, LYS160C, LYS161C, LYS165C, LYS169C, LYS37L, LYS62L, PHE104C, PHE62C, PHE67L, SER35L, SER48C, THR156C, THR53C, THR55C, THR61L, TRP170C, VAL158C, VAL49C, VAL51C, VAL65L
• D-G: ALA178D, ALA184D, ALA188D, ALA191D, ALA24D, ALA25D, ALA49D, ALA55D, ALA62D, ALA69D, ALA76G, ARG119D, ARG13D, ARG142G, ARG144G, ARG153D, ARG21G, ARG56D, ARG66D, ARG67D, ARG68D, ARG72D, ARG75G, ASN10G, ASN137D, ASN138D, ASN143D, ASN150D, ASN23D, ASN39D, ASN51D, ASN53G, ASN71G, ASP140D, ASP166G, ASP186D, ASP189D, ASP50G, ASP52G, ASP55G, ASP6G, ASP88G, CYS150G, CYS185D, CYS38G, CYS47G, GLN102G, GLN146D, GLN179D, GLN24G, GLN28D, GLN31D, GLN34D, GLN37D, GLN41D, GLN57G, GLN74D, GLN9D, GLU148G, GLU165G, GLU176D, GLU190D, GLU20D, GLU21D, GLU22D, GLU32D, GLU32G, GLU33G, GLU35G, GLU45D, GLU46D, GLU54D, GLU61D, GLU65D, GLU85G, GLY104G, GLY135D, GLY136D, GLY149G, GLY169G, GLY30D, GLY36G, GLY40G, GLY42D, GLY43G, GLY84G, GLY89G, HIS158G, HIS173D, HIS40D, ILE11G, ILE143G, ILE147G, ILE171G, ILE195D, ILE38D, ILE45G, ILE48D, ILE4G, ILE54G, ILE59D, LEU123D, LEU130D, LEU141D, LEU148D, LEU168G, LEU180D, LEU183D, LEU194D, LEU27D, LEU29D, LEU30G, LEU31G, LEU46G, LEU47D, LEU49G, LEU50D, LEU52D, LEU57D, LEU63D, LEU7G, LEU9G, LYS107G, LYS139D, LYS140G, LYS142D, LYS146G, LYS192D, LYS27G, LYS41G, LYS5G, LYS60D, LYS73G, LYS75D, LYS76D, LYS80G, LYS83G, MET106G, MET145D, MET1G, PHE151D, PHE175D, PHE2G, PHE33D, PHE3G, PHE42G, PHE70D, PHE79G, PHE82G, PHE8D, PRO105G, PRO174D, PRO196D, PRO81G, SER141G, SER152D, SER155G, SER156G, SER182D, SER197D, SER37G, SER4D, SER53D, SER6D, SER73D, SER8G, THR133D, THR134D, THR144D, THR149D, THR187D, THR193D, THR26D, THR28G, THR39G, THR5D, THR7D, THR90G, TYR147D, TYR167G, TYR221D, TYR44G, TYR51G, TYR74G, VAL101G, VAL103G, VAL145G, VAL177D, VAL34G, VAL48G, VAL58D, VAL72G, VAL77G, VAL78G, VAL86G, VAL87G, VAL91G, VAL92G
• E-F: ALA73F, ALA80F, ARG167E, ARG169E, ARG79F, ASP140F, GLN174E, GLN78F, GLU144F, GLY141F, ILE74F, LEU138F, LEU170E, LYS166E, LYS171E, LYS72F, PHE143F, PRO139F, PRO75F, SER142F, THR81F, TYR168E
• E-S: ALA194S, ARG52E, ASN191S, ASP2E, CYS188S, GLN3E, GLU192S, MET50E
• F-G: ALA105F, ALA68G, ALA73F, ARG135F, ARG21G, ARG58G, ARG60G, ARG92F, ARG97F, ASN104F, ASP145F, ASP65G, GLN100F, GLN57G, GLU144F, GLU150F, GLY19G, GLY59G, GLY66G, GLY95F, HIS14G, ILE101F, ILE134F, ILE61G, ILE93F, LEU132F, LEU13G, LEU62G, LEU99F, LYS76F, MET103F, MET22G, PHE108F, PHE143F, PHE17G, PHE18G, PRO106F, PRO131F, PRO15G, PRO20G, PRO63G, SER102F, SER147F, SER16G, SER67G, THR64G, THR96F, TRP146F, TYR137F, VAL107F, VAL133F, VAL148F
• H-K: ALA27K, ALA59K, ALA84H, ARG54K, ARG74K, ARG80H, ARG87H, ASN29K, ASP53K, ASP86H, GLN76K, GLN83H, GLU79K, GLY85H, LEU51K, LEU57K, LYS55K, PHE58K, PRO28K, PRO81H, PRO82H, SER78H, THR77K, THR78K, TRP79H, VAL56K
• J-L: ALA32L, ASN64J, CYS31L, CYS34L, GLU33L, ILE30L, LEU57L, PRO65J, SER35L, SER36L
• K-L: ARG6K, ARG70L, ASP5K, PHE10K, PHE7K