3PMK

crystal structure of the vesicular stomatitis virus rna free nucleoprotein/phosphoprotein complex

• Total interactions analyzed: 45
• Total true interactions: 17
• Strongest Interaction:
  • Chains: C-P
  • Int. Res.: 17
  • Norm. En. per Res.: -4.3273
• Hub Node: C(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-D	-52.9891	-92.3355	-406.238	-551.5626	185	15	10	17370	8	60	48
A-O	-6.86	-4.9574	-64.3926	-76.21	20	3	0	2758	0	3	3
A-R	-44.2359	-57.0835	-346.003	-447.3224	109	12	9	13322	5	61	40
B-C	-39.3588	-127.2384	-393.578	-560.1752	189	15	9	17168	8	58	49
B-P	-62.6202	-38.0835	-340.984	-441.6877	107	11	9	13320	4	63	39
B-Q	0.0	83.4124	-21.65	61.7624	27	0	0	929	0	10	23
C-E	-33.9801	-79.1067	-400.486	-513.5728	189	11	8	17384	6	64	50
C-N	0.0	104.3065	-29.2316	75.0749	29	0	0	1179	0	12	24
C-P	-28.1201	2.6724	-48.1163	-73.564	17	4	1	2046	0	5	3
C-Q	-51.7874	-61.4906	-371.245	-484.523	117	8	9	14261	6	65	41
D-E	-13.9677	-102.7777	-370.644	-487.3894	181	7	9	16271	4	60	48
D-N	0.0	2.8813	-50.8359	-47.9546	17	0	1	2170	0	4	3
D-O	-59.7789	-52.1864	-340.002	-451.9673	116	18	9	13358	7	62	32
D-R	0.0	112.8502	-25.3517	87.4985	27	0	0	1025	0	11	23
E-N	-73.0332	-37.1377	-353.445	-463.616	112	14	9	13653	3	61	39
E-O	0.0	109.6395	-25.4283	84.2112	26	0	0	1022	0	9	23
E-Q	-16.8325	-0.8628	-75.059	-92.7543	23	8	1	2768	0	4	3

Interface residues

• A-D: ALA20D, ALA229A, ALA255D, ALA271A, ALA305A, ALA313A, ALA330D, ALA335A, ALA337A, ALA342A, ALA345A, ALA368A, ALA397A, ALA400A, ARG179D, ARG214A, ARG221A, ARG252D, ARG309A, ARG312A, ARG314A, ARG373A, ARG387D, ARG399A, ASN162A, ASN168A, ASN187D, ASN251D, ASN315A, ASN353A, ASN386D, ASN63D, ASP119D, ASP180D, ASP183D, ASP188D, ASP23D, ASP244D, ASP256D, ASP272A, ASP320D, ASP321D, ASP343A, ASP352A, ASP358A, ASP359A, ASP374D, ASP384D, ASP392A, ASP421D, CYS164A, CYS235A, CYS349A, GLN163A, GLN170A, GLN260D, GLN318D, GLN346A, GLN347A, GLN371A, GLN395A, GLN405A, GLU169A, GLU22D, GLU243D, GLU253D, GLU257D, GLU26D, GLU323D, GLU377D, GLU383D, GLU409D, GLU419D, GLY186D, GLY232A, GLY239A, GLY331D, GLY339A, GLY351A, GLY362A, GLY363A, GLY372A, GLY380D, HIS203A, HIS233A, HIS68D, ILE167A, ILE181D, ILE218A, ILE237A, ILE249D, ILE322D, ILE66D, ILE67D, LEU117D, LEU234A, LEU250D, LEU307A, LEU308A, LEU327D, LEU332D, LEU333D, LEU344A, LEU364A, LEU379D, LEU404A, LYS165A, LYS206A, LYS207A, LYS236A, LYS286D, LYS354A, LYS388D, LYS398A, LYS398D, LYS410D, LYS414D, LYS417D, LYS422D, MET166A, MET21D, MET240A, MET258D, MET262D, MET393D, MET394D, MET402A, PHE171A, PHE222A, PHE297D, PHE299D, PHE348A, PHE382D, PHE420D, PRO118D, PRO24D, PRO295D, PRO319D, PRO357A, PRO369A, PRO389D, SER241D, SER284D, SER285D, SER310A, SER326D, SER340A, SER341A, SER360A, SER403A, SER418D, SER65D, THR161A, THR238A, THR246D, THR247D, THR311A, THR325D, THR328D, THR329D, THR356A, THR361A, THR411D, TRP185D, TRP248D, TRP300D, TRP378D, TRP381D, TYR324D, TYR334D, TYR336A, TYR355A, TYR396A, TYR415D, VAL184D, VAL245D, VAL254D, VAL259D, VAL338A, VAL350A, VAL375D, VAL376D, VAL401A, VAL64D, VAL69D
• A-O: ALA345A, ARG8O, ASN353A, ASP352A, CYS349A, GLN346A, GLN347A, GLU9O, GLY351A, LYS12O, LYS354A, LYS6O, PHE348A, PRO357A, THR356A, THR5O, TYR10O, TYR355A, VAL350A, VAL7O
• A-R: ALA20R, ALA226A, ALA227A, ALA229A, ALA255A, ALA271A, ALA29A, ALA29R, ALA32R, ARG143A, ARG146A, ARG153A, ARG16R, ARG214A, ARG221A, ARG252A, ARG312A, ARG31R, ARG408A, ARG8R, ASN315A, ASP18R, ASP199A, ASP224A, ASP244A, ASP25R, ASP269A, ASP272A, CYS225A, CYS235A, GLN148A, GLN19R, GLN260A, GLN266A, GLN302A, GLN30R, GLU151A, GLU23R, GLU243A, GLU267A, GLU26R, GLU28R, GLU33R, GLU9R, GLY22R, GLY232A, GLY265A, HIS203A, HIS233A, HIS298A, ILE218A, ILE237A, ILE249A, ILE24R, ILE268A, ILE27R, LEU11R, LEU156A, LEU17R, LEU228A, LEU234A, LEU263A, LYS12R, LYS155A, LYS206A, LYS223A, LYS236A, LYS270A, LYS34R, LYS6R, MET149A, MET240A, MET258A, MET261A, MET262A, MET275A, PHE222A, PHE231A, PHE297A, PHE91A, PRO150A, PRO264A, PRO276A, PRO28A, SER13R, SER15R, SER220A, SER241A, SER291A, THR147A, THR217A, THR230A, THR242A, THR246A, THR247A, TYR10R, TYR142A, TYR14R, TYR152A, TYR215A, TYR277A, TYR27A, TYR289A, VAL219A, VAL21R, VAL245A, VAL259A, VAL376A, VAL7R
• B-C: ALA129C, ALA20B, ALA211C, ALA229C, ALA255B, ALA271C, ALA305C, ALA313C, ALA330B, ALA335C, ALA337C, ALA342C, ALA345C, ALA368C, ALA400C, ARG126C, ARG179B, ARG214C, ARG221C, ARG252B, ARG309C, ARG312C, ARG314C, ARG373C, ARG387B, ARG399C, ASN162C, ASN168C, ASN187B, ASN251B, ASN315C, ASN353C, ASN386B, ASN63B, ASP119B, ASP180B, ASP183B, ASP188B, ASP23B, ASP244B, ASP256B, ASP272C, ASP320B, ASP321B, ASP343C, ASP352C, ASP358C, ASP359C, ASP374B, ASP384B, ASP392C, ASP421B, CYS164C, CYS235C, CYS349C, GLN163C, GLN170C, GLN260B, GLN318B, GLN346C, GLN347C, GLN371C, GLN395C, GLN405C, GLU169C, GLU22B, GLU243B, GLU253B, GLU257B, GLU26B, GLU323B, GLU377B, GLU383B, GLU409B, GLU419B, GLY186B, GLY19B, GLY232C, GLY239C, GLY282B, GLY331B, GLY339C, GLY351C, GLY362C, GLY363C, GLY372C, GLY380B, GLY62B, HIS203C, HIS233C, ILE167C, ILE181B, ILE218C, ILE237C, ILE249B, ILE322B, ILE66B, ILE67B, LEU117B, LEU234C, LEU250B, LEU307C, LEU308C, LEU327B, LEU332B, LEU333B, LEU344C, LEU364C, LEU379B, LEU404C, LYS165C, LYS206C, LYS207C, LYS236C, LYS286B, LYS34B, LYS354C, LYS388B, LYS398B, LYS398C, LYS410B, LYS414B, LYS417B, LYS422B, MET166C, MET21B, MET240C, MET258B, MET262B, MET393B, MET394B, MET402C, PHE182B, PHE202C, PHE222C, PHE297B, PHE299B, PHE348C, PHE382B, PHE420B, PRO118B, PRO24B, PRO295B, PRO319B, PRO357C, PRO369C, PRO389B, SER284B, SER285B, SER310C, SER326B, SER340C, SER341C, SER360C, SER403C, SER418B, SER65B, THR161C, THR238C, THR246B, THR247B, THR311C, THR325B, THR328B, THR329B, THR356C, THR361C, THR411B, TRP185B, TRP248B, TRP300B, TRP378B, TRP381B, TYR324B, TYR334B, TYR336C, TYR355C, TYR396C, TYR415B, VAL184B, VAL245B, VAL254B, VAL259B, VAL338C, VAL350C, VAL375B, VAL376B, VAL401C, VAL64B
• B-P: ALA20P, ALA226B, ALA227B, ALA229B, ALA255B, ALA271B, ALA29P, ALA32P, ARG143B, ARG146B, ARG153B, ARG16P, ARG214B, ARG221B, ARG252B, ARG312B, ARG31P, ARG408B, ARG8P, ASN315B, ASP18P, ASP199B, ASP224B, ASP244B, ASP256B, ASP25P, ASP269B, ASP272B, CYS225B, CYS235B, GLN148B, GLN19P, GLN260B, GLN266B, GLN302B, GLN30P, GLU151B, GLU23P, GLU243B, GLU267B, GLU26P, GLU28P, GLU33P, GLU9P, GLY22P, GLY232B, GLY265B, HIS203B, HIS233B, HIS298B, ILE218B, ILE237B, ILE249B, ILE24P, ILE268B, ILE27P, LEU11P, LEU156B, LEU17P, LEU228B, LEU234B, LEU263B, LYS12P, LYS155B, LYS206B, LYS223B, LYS236B, LYS270B, LYS34P, LYS6P, MET149B, MET240B, MET258B, MET261B, MET262B, MET275B, PHE222B, PHE231B, PHE297B, PHE91B, PRO150B, PRO264B, PRO276B, SER13P, SER15P, SER220B, SER241B, SER291B, THR147B, THR217B, THR230B, THR242B, THR246B, THR247B, TYR10P, TYR142B, TYR14P, TYR152B, TYR215B, TYR277B, TYR27B, TYR289B, VAL219B, VAL21P, VAL245B, VAL259B, VAL7P
• B-Q: ALA20B, ALA20Q, ALA29Q, ALA32Q, ARG16Q, ASP23B, ASP25Q, ASP320B, ASP321B, GLN19Q, GLU22B, GLU23Q, GLU26Q, GLU28Q, GLU33Q, GLU409B, GLY19B, GLY22Q, ILE24Q, ILE27Q, LYS293B, LYS34Q, LYS410B, MET21B, PRO24B, VAL21Q, VAL292B
• C-E: ALA20C, ALA229E, ALA255C, ALA271E, ALA305E, ALA313E, ALA330C, ALA335E, ALA342E, ALA345E, ALA368E, ALA400E, ARG214E, ARG221E, ARG252C, ARG309E, ARG312E, ARG314E, ARG373E, ARG387C, ARG399E, ASN162E, ASN168E, ASN187C, ASN251C, ASN315E, ASN353E, ASN386C, ASN63C, ASP119C, ASP158E, ASP180C, ASP183C, ASP188C, ASP23C, ASP244C, ASP256C, ASP272E, ASP320C, ASP321C, ASP343E, ASP352E, ASP358E, ASP359E, ASP374C, ASP384C, ASP392E, ASP421C, ASP421E, CYS164E, CYS235E, CYS349E, GLN163E, GLN170E, GLN260C, GLN318C, GLN346E, GLN347E, GLN371E, GLN395C, GLN395E, GLN405E, GLU169E, GLU172E, GLU22C, GLU243C, GLU253C, GLU257C, GLU26C, GLU323C, GLU377C, GLU383C, GLU409C, GLU419C, GLY115C, GLY186C, GLY232E, GLY239E, GLY331C, GLY339E, GLY351E, GLY362E, GLY363E, GLY372E, GLY380C, GLY62C, HIS203E, HIS233E, ILE167E, ILE181C, ILE218E, ILE237E, ILE249C, ILE322C, ILE66C, ILE67C, LEU117C, LEU234E, LEU250C, LEU307E, LEU308E, LEU327C, LEU332C, LEU333C, LEU344E, LEU364E, LEU379C, LEU404E, LYS165E, LYS206E, LYS207E, LYS236E, LYS270E, LYS286C, LYS34C, LYS354E, LYS388C, LYS398C, LYS398E, LYS410C, LYS414C, LYS417C, LYS422C, MET166E, MET21C, MET240E, MET258C, MET262C, MET393C, MET394C, MET402E, PHE171E, PHE202E, PHE222E, PHE297C, PHE299C, PHE348E, PHE382C, PHE420C, PRO24C, PRO276E, PRO295C, PRO319C, PRO357E, PRO369E, PRO370E, PRO389C, SER241C, SER284C, SER285C, SER310E, SER326C, SER340E, SER341E, SER360E, SER403E, SER418C, SER65C, THR161E, THR238E, THR246C, THR247C, THR311E, THR325C, THR328C, THR329C, THR356E, THR361E, THR411C, TRP185C, TRP248C, TRP300C, TRP378C, TRP381C, TYR324C, TYR334C, TYR336E, TYR355E, TYR396E, TYR415C, VAL184C, VAL245C, VAL254C, VAL259C, VAL338E, VAL350E, VAL375C, VAL376C, VAL64C
• C-N: ALA20C, ALA20N, ALA29N, ALA32N, ARG16N, ASP23C, ASP25N, ASP320C, ASP321C, GLN19N, GLN30N, GLU22C, GLU23N, GLU26N, GLU28N, GLU409C, GLY19C, GLY22N, ILE24N, ILE27N, LYS286C, LYS293C, LYS34N, LYS410C, MET21C, PRO24C, PRO295C, VAL21N, VAL292C
• C-P: ALA345C, ARG8P, ASN353C, ASP352C, CYS349C, GLN346C, GLN347C, GLU9P, GLY351C, LYS12P, LYS354C, LYS6P, PHE348C, TYR10P, TYR355C, VAL350C, VAL7P
• C-Q: ALA20Q, ALA226C, ALA227C, ALA229C, ALA255C, ALA271C, ALA29Q, ALA32Q, ARG143C, ARG146C, ARG153C, ARG16Q, ARG214C, ARG221C, ARG252C, ARG312C, ARG314C, ARG31Q, ARG408C, ARG8Q, ASN251C, ASN315C, ASP18Q, ASP199C, ASP224C, ASP244C, ASP256C, ASP25Q, ASP269C, ASP272C, CYS225C, CYS235C, GLN148C, GLN19Q, GLN260C, GLN266C, GLN302C, GLN30Q, GLU151C, GLU23Q, GLU243C, GLU253C, GLU257C, GLU267C, GLU26Q, GLU28Q, GLU33Q, GLU9Q, GLY22Q, GLY232C, GLY265C, HIS203C, HIS233C, HIS298C, ILE218C, ILE237C, ILE249C, ILE24Q, ILE268C, ILE27Q, LEU11Q, LEU156C, LEU17Q, LEU228C, LEU234C, LEU250C, LEU263C, LYS12Q, LYS155C, LYS223C, LYS236C, LYS270C, LYS34Q, LYS6Q, MET149C, MET240C, MET258C, MET261C, MET262C, MET275C, PHE222C, PHE231C, PHE297C, PHE91C, PRO150C, PRO264C, PRO276C, PRO28C, SER13Q, SER15Q, SER220C, SER241C, SER273C, SER291C, SER310C, THR147C, THR217C, THR230C, THR242C, THR246C, THR247C, THR5Q, TYR10Q, TYR142C, TYR14Q, TYR152C, TYR215C, TYR277C, TYR27C, TYR289C, VAL219C, VAL21Q, VAL245C, VAL254C, VAL259C, VAL376C, VAL7Q
• D-E: ALA20E, ALA229D, ALA255E, ALA271D, ALA305D, ALA313D, ALA330E, ALA335D, ALA337D, ALA342D, ALA345D, ALA368D, ALA400D, ARG126D, ARG214D, ARG221D, ARG252E, ARG309D, ARG312D, ARG314D, ARG373D, ARG387E, ARG399D, ASN162D, ASN168D, ASN187E, ASN251E, ASN315D, ASN353D, ASN386E, ASN63E, ASP180E, ASP183E, ASP188E, ASP23E, ASP244E, ASP256E, ASP272D, ASP320E, ASP321E, ASP343D, ASP352D, ASP358D, ASP359D, ASP374E, ASP384E, ASP392D, ASP421E, CYS164D, CYS235D, CYS349D, GLN163D, GLN170D, GLN260E, GLN318E, GLN346D, GLN347D, GLN371D, GLN395D, GLN405D, GLU169D, GLU22E, GLU243E, GLU253E, GLU257E, GLU26E, GLU323E, GLU377E, GLU383E, GLU409E, GLU419E, GLY186E, GLY232D, GLY239D, GLY331E, GLY339D, GLY351D, GLY362D, GLY363D, GLY372D, GLY380E, GLY62E, HIS203D, HIS233D, ILE167D, ILE181E, ILE218D, ILE237D, ILE249E, ILE322E, ILE66E, ILE67E, LEU117E, LEU234D, LEU250E, LEU306D, LEU307D, LEU308D, LEU327E, LEU332E, LEU333E, LEU344D, LEU364D, LEU379E, LEU404D, LYS165D, LYS206D, LYS207D, LYS236D, LYS286E, LYS34E, LYS354D, LYS388E, LYS398D, LYS398E, LYS410E, LYS414E, LYS417E, LYS422E, MET166D, MET21E, MET240D, MET258E, MET262E, MET393E, MET394E, MET402D, PHE222D, PHE297E, PHE299E, PHE348D, PHE382E, PHE420E, PRO24E, PRO295E, PRO319E, PRO357D, PRO369D, PRO389E, SER284E, SER285E, SER310D, SER326E, SER340D, SER341D, SER360D, SER403D, SER418E, SER65E, THR161D, THR238D, THR246E, THR247E, THR304D, THR311D, THR325E, THR328E, THR329E, THR356D, THR361D, THR411E, TRP185E, TRP248E, TRP300E, TRP378E, TRP381E, TYR324E, TYR334E, TYR336D, TYR355D, TYR396D, TYR415E, VAL184E, VAL245E, VAL254E, VAL259E, VAL338D, VAL350D, VAL375E, VAL376E, VAL64E
• D-N: ALA345D, ARG8N, ASN353D, ASP352D, CYS349D, GLN346D, GLN347D, GLU9N, GLY351D, LYS12N, LYS354D, LYS6N, PHE348D, TYR10N, TYR355D, VAL350D, VAL7N
• D-O: ALA20O, ALA226D, ALA227D, ALA229D, ALA255D, ALA271D, ALA29D, ALA29O, ALA32O, ARG143D, ARG146D, ARG153D, ARG16O, ARG214D, ARG221D, ARG252D, ARG312D, ARG31O, ARG408D, ARG8O, ASN251D, ASN315D, ASP18O, ASP199D, ASP224D, ASP244D, ASP256D, ASP25O, ASP269D, ASP272D, ASP280D, CYS225D, CYS235D, GLN148D, GLN19O, GLN260D, GLN266D, GLN302D, GLN30O, GLU151D, GLU23O, GLU243D, GLU253D, GLU257D, GLU267D, GLU26O, GLU28O, GLU33O, GLU9O, GLY22O, GLY232D, GLY265D, HIS203D, HIS233D, HIS298D, ILE218D, ILE237D, ILE249D, ILE24O, ILE268D, ILE27O, LEU11O, LEU156D, LEU17O, LEU228D, LEU234D, LEU263D, LYS12O, LYS155D, LYS206D, LYS223D, LYS236D, LYS270D, LYS6O, MET149D, MET240D, MET258D, MET261D, MET262D, MET275D, PHE222D, PHE231D, PHE297D, PHE91D, PRO150D, PRO264D, PRO276D, PRO28D, SER13O, SER15O, SER220D, SER241D, SER291D, SER310D, THR147D, THR217D, THR230D, THR242D, THR246D, THR247D, THR311D, THR5O, TYR10O, TYR142D, TYR14O, TYR152D, TYR215D, TYR277D, TYR27D, TYR289D, VAL219D, VAL21O, VAL245D, VAL254D, VAL259D, VAL7O
• D-R: ALA20D, ALA20R, ALA29R, ALA32R, ARG16R, ASP23D, ASP25R, ASP320D, ASP321D, GLN19R, GLN30R, GLU22D, GLU23R, GLU26R, GLU28R, GLU409D, GLY19D, GLY22R, ILE24R, ILE27R, LYS286D, LYS293D, LYS34R, LYS410D, MET21D, PRO24D, VAL21R
• E-N: ALA20N, ALA226E, ALA227E, ALA229E, ALA255E, ALA271E, ALA29E, ALA29N, ALA32N, ARG143E, ARG146E, ARG153E, ARG16N, ARG214E, ARG221E, ARG252E, ARG312E, ARG314E, ARG31N, ARG408E, ARG8N, ASN315E, ASP18N, ASP199E, ASP224E, ASP244E, ASP256E, ASP25N, ASP269E, ASP272E, CYS225E, CYS235E, GLN148E, GLN19N, GLN260E, GLN266E, GLN302E, GLN30N, GLU151E, GLU23N, GLU243E, GLU267E, GLU26N, GLU28N, GLU33N, GLU9N, GLY22N, GLY232E, GLY265E, HIS203E, HIS233E, HIS298E, ILE218E, ILE237E, ILE249E, ILE24N, ILE268E, ILE27N, LEU11N, LEU156E, LEU17N, LEU228E, LEU234E, LEU263E, LYS12N, LYS155E, LYS223E, LYS236E, LYS270E, LYS34N, LYS6N, MET149E, MET240E, MET258E, MET261E, MET262E, MET275E, PHE222E, PHE231E, PHE297E, PHE91E, PRO150E, PRO264E, PRO276E, PRO28E, SER13N, SER15N, SER220E, SER241E, SER291E, SER310E, SER35N, THR147E, THR217E, THR230E, THR242E, THR246E, THR247E, THR311E, TYR10N, TYR142E, TYR14N, TYR152E, TYR215E, TYR277E, TYR27E, TYR289E, VAL219E, VAL21N, VAL245E, VAL259E, VAL7N
• E-O: ALA20E, ALA20O, ALA29O, ALA32O, ARG16O, ASP23E, ASP25O, ASP320E, ASP321E, GLN19O, GLN30O, GLU22E, GLU23O, GLU26O, GLU33O, GLY19E, GLY22O, ILE24O, ILE27O, LYS286E, LYS293E, LYS410E, MET21E, PRO24E, VAL21O, VAL292E
• E-Q: ALA345E, ARG8Q, ASN353E, ASP343E, ASP352E, CYS349E, GLN346E, GLN347E, GLU9Q, GLY351E, LEU11Q, LEU344E, LYS12Q, LYS354E, LYS6Q, PHE348E, PRO357E, THR356E, THR5Q, TYR10Q, TYR355E, VAL350E, VAL7Q