3PLF

reverse binding mode of metrd peptide complexed with c-cbl tkb domain

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 33
  • Norm. En. per Res.: -2.4484
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-18.3498	0.0	-62.446	-80.7958	33	4	0	1801	0	5	6
B-D	-21.5214	0.499	-136.298	-157.3204	125	3	9	7492	0	39	43
C-D	-11.4008	0.0	-57.0746	-68.4754	32	4	1	1832	0	5	6

Interface residues

• A-B: ALA1005A, ARG1002A, ARG294B, ARG299B, ASN313B, ASN79B, ASP1004A, ASP275B, CYS297B, GLN316B, GLU276B, HIS320B, ILE305B, ILE314B, ILE318B, LEU315B, LYS278B, LYS322B, LYS78B, PHE336B, PRO319B, PRO81B, PRO82B, SER296B, SER80B, THR273B, THR298B, THR309B, THR317B, TYR274B, TYR307B, TYR337B, TYR83B
• B-D: ALA221B, ALA221D, ALA223B, ALA223D, ALA262B, ALA262D, ALA270B, ALA270D, ARG139B, ARG139D, ARG149B, ARG149D, ARG206B, ARG206D, ARG280B, ARG280D, ARG343B, ARG343D, ASN144B, ASN144D, ASN150B, ASN150D, ASN259B, ASN259D, ASP234B, ASP234D, ASP341B, ASP341D, GLN128B, GLN128D, GLN146B, GLN146D, GLN207B, GLN207D, GLU120B, GLU120D, GLU135B, GLU135D, GLU143B, GLU220B, GLU220D, GLY218B, GLY218D, GLY267B, GLY267D, GLY49B, GLY49D, HIS210B, HIS210D, HIS213B, HIS213D, HIS265B, HIS265D, ILE215B, ILE215D, LEU132B, LEU132D, LEU219B, LEU219D, LEU224B, LEU224D, LEU261B, LEU261D, LYS124B, LYS124D, LYS127B, LYS127D, LYS134B, LYS134D, LYS137B, LYS137D, LYS153B, LYS153D, LYS203B, LYS203D, LYS225B, LYS225D, LYS283B, LYS283D, LYS58B, MET123D, MET222B, MET222D, MET269B, MET269D, PHE244B, PHE244D, PHE248B, PHE248D, PHE271B, PHE271D, PRO201B, PRO201D, PRO214B, PRO214D, PRO266B, PRO266D, PRO340B, PRO340D, PRO347B, PRO347D, SER131B, SER131D, SER145B, SER145D, SER216B, SER216D, SER217B, SER217D, SER226B, SER226D, THR227B, THR227D, THR264B, THR264D, TRP202B, TRP202D, TRP258B, TRP258D, TYR235B, TYR235D, TYR268B, TYR268D, VAL263B, VAL263D
• C-D: ALA1005C, ARG1002C, ARG294D, ARG299D, ASN313D, ASN79D, ASP1004C, ASP275D, CYS297D, GLN316D, GLU276D, HIS320D, ILE305D, ILE314D, ILE318D, LEU156D, LEU315D, LYS278D, LYS78D, PHE336D, PRO319D, PRO81D, PRO82D, SER296D, SER80D, THR273D, THR298D, THR309D, THR317D, TYR274D, TYR307D, TYR83D