3PHW

otu domain of crimean congo hemorrhagic fever virus in complex with ubiquitin

• Total interactions analyzed: 28
• Total true interactions: 15
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 95
  • Norm. En. per Res.: -4.1542
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-29.516	-70.7923	-272.639	-372.9472	92	11	8	11111	2	26	20
A-C	0.0	17.1109	-48.2243	-31.1134	53	3	2	2508	0	18	21
A-G	-9.2338	-38.8783	-38.0591	-86.1712	46	4	0	2408	2	16	13
A-H	0.0	-19.5472	-88.4977	-108.045	45	5	0	3259	2	20	23
B-C	0.0	0.0	-11.011	-11.011	15	0	0	646	0	1	0
B-D	0.0	0.0	-22.4648	-22.4648	28	0	1	1254	0	2	6
B-G	0.0	-14.8996	-79.5492	-94.4488	48	1	0	3261	2	19	25
B-H	0.0	0.0	-1.0463	-1.0463	7	0	0	121	0	2	3
C-D	-17.1066	-76.8985	-269.883	-363.8882	93	8	8	11307	2	28	21
C-E	-2.4933	-36.746	-48.2171	-87.4564	49	3	0	2545	2	16	12
C-F	-7.9886	-19.6603	-78.3719	-106.0208	47	3	0	3180	1	22	25
D-E	0.0	-18.4367	-63.9476	-82.3843	44	4	0	2867	1	18	22
D-F	0.0	7.6522	-0.2783	7.374	7	0	0	43	0	2	3
E-F	-39.675	-80.7446	-274.228	-394.6476	95	14	8	11441	4	29	19
G-H	-15.1353	-72.3912	-270.523	-358.0495	98	10	8	11342	4	29	21

Interface residues

• A-B: ALA105A, ALA129A, ALA14A, ALA46B, ALA79A, ARG22A, ARG42B, ARG54B, ARG72B, ARG74B, ARG80A, ARG92A, ASN20A, ASN39A, ASP37A, ASP39B, ASP52B, ASP8A, CYS40A, GLN11A, GLN149A, GLN16A, GLN40B, GLN41B, GLN49B, GLU104A, GLU128A, GLU51B, GLU76A, GLU78A, GLU98A, GLY100A, GLY10B, GLY130A, GLY148A, GLY38A, GLY47B, GLY75B, HIS146A, HIS151A, HIS68B, ILE118A, ILE131A, ILE13A, ILE36B, ILE44B, LEU103A, LEU43B, LEU50B, LEU69B, LEU71B, LEU73B, LEU81A, LEU84A, LEU8B, LYS11B, LYS132A, LYS27B, LYS48B, LYS6B, MET107A, PHE133A, PHE152A, PHE41A, PHE45B, PRO37B, PRO38B, PRO77A, SER101A, SER106A, SER147A, SER19A, THR102A, THR10A, THR120A, THR150A, THR7B, THR9B, TRP119A, TRP99A, TRP9A, TYR17A, TYR42A, TYR59B, TYR73A, TYR89A, VAL121A, VAL127A, VAL12A, VAL18A, VAL70B, VAL82A
• A-C: ALA109A, ALA109C, ALA14A, ALA14C, ARG80A, ASP135A, ASP135C, ASP137A, ASP137C, ASP8A, GLN11A, GLN11C, GLN16A, GLN16C, GLU111C, GLU75A, GLU75C, GLU76A, GLU76C, GLY113A, GLY113C, GLY134A, GLY134C, GLY136A, GLY136C, GLY15A, GLY15C, ILE114C, ILE13A, ILE13C, LEU7A, LYS110A, LYS110C, LYS132A, LYS132C, LYS71A, LYS71C, MET107C, MET112C, PRO77A, PRO77C, THR10A, THR115A, THR115C, THR140A, THR140C, TRP9A, TYR17A, TYR17C, TYR72A, TYR72C, VAL12A, VAL138C
• A-G: ARG92A, ARG92G, ASN39A, ASN39G, ASN97A, ASN97G, ASP37A, ASP37G, ASP88A, ASP88G, ASP96A, ASP96G, GLN149A, GLN149G, GLU98A, GLU98G, GLY148A, GLY148G, GLY36A, GLY36G, GLY38A, GLY38G, GLY83A, GLY83G, HIS146A, HIS146G, LEU81A, LEU81G, LEU84A, LEU84G, LEU94A, LEU94G, LYS62A, LYS91A, LYS91G, MET93A, SER147A, SER147G, SER95A, SER95G, THR150A, THR150G, TRP99A, TRP99G, VAL82A, VAL82G
• A-H: ALA28H, ARG33A, ARG72H, ARG74H, ARG92A, ASN39A, ASN97A, ASP153A, ASP32H, ASP37A, ASP39H, ASP52H, CYS40A, GLN149A, GLN31H, GLN34A, GLN40H, GLN41H, GLU24H, GLU34H, GLU98A, GLY148A, GLY35H, GLY36A, GLY38A, GLY75H, HIS146A, HIS151A, ILE30H, ILE31A, ILE36H, LEU145A, LEU71H, LEU73H, LYS27H, LYS29H, LYS33H, PHE152A, PRO35A, PRO37H, PRO38H, SER147A, THR150A, TRP99A, VAL121A
• B-C: ALA14C, ALA46B, GLN11C, GLN16C, GLN49B, GLY15C, GLY47B, ILE13C, ILE44B, LYS48B, PHE45B, THR10C, TRP9C, TYR17C, VAL12C
• B-D: ALA46B, ALA46D, ASN60B, ASN60D, GLN62B, GLN62D, GLU64B, GLU64D, GLY47B, GLY47D, HIS68B, HIS68D, ILE44D, ILE61B, ILE61D, LYS48B, LYS48D, LYS63B, LYS63D, PHE45B, PHE45D, PHE4B, SER65B, SER65D, THR66B, THR66D, TYR59B, TYR59D
• B-G: ALA122G, ALA123G, ALA28B, ARG33G, ARG72B, ARG74B, ARG92G, ASN39G, ASN97G, ASP125G, ASP153G, ASP32B, ASP37G, ASP39B, ASP52B, CYS40G, GLN149G, GLN31B, GLN34G, GLN40B, GLN41B, GLU24B, GLU34B, GLU98G, GLY148G, GLY35B, GLY36G, GLY38G, GLY75B, HIS146G, HIS151G, ILE30B, ILE31G, ILE36B, LEU145G, LEU71B, LEU73B, LYS27B, LYS33B, PHE152G, PRO35G, PRO37B, PRO38B, SER124G, SER147G, THR150G, TRP99G, VAL121G
• B-H: ARG74B, ARG74H, ASP39B, ASP39H, GLY75B, GLY75H, PRO37H
• C-D: ALA105C, ALA129C, ALA14C, ALA46D, ALA79C, ARG22C, ARG42D, ARG54D, ARG72D, ARG74D, ARG80C, ARG92C, ASN20C, ASN39C, ASP37C, ASP39D, ASP52D, ASP8C, CYS40C, GLN11C, GLN149C, GLN16C, GLN40D, GLN41D, GLN49D, GLU104C, GLU128C, GLU51D, GLU76C, GLU78C, GLU98C, GLY100C, GLY10D, GLY130C, GLY148C, GLY38C, GLY47D, GLY75D, HIS146C, HIS151C, HIS68D, ILE118C, ILE131C, ILE13C, ILE36D, ILE44D, LEU103C, LEU43D, LEU50D, LEU69D, LEU71D, LEU73D, LEU81C, LEU84C, LEU8D, LYS11D, LYS132C, LYS27D, LYS48D, LYS6D, MET107C, MET93C, PHE133C, PHE152C, PHE41C, PHE45D, PRO37D, PRO38D, PRO77C, SER101C, SER106C, SER147C, SER19C, THR102C, THR10C, THR120C, THR150C, THR7D, THR9D, TRP119C, TRP99C, TRP9C, TYR17C, TYR42C, TYR59D, TYR73C, TYR89C, VAL121C, VAL127C, VAL12C, VAL18C, VAL70D, VAL82C
• C-E: ARG80C, ARG80E, ARG92C, ARG92E, ASN39C, ASN39E, ASN97C, ASN97E, ASP37C, ASP37E, ASP88C, ASP88E, ASP96C, ASP96E, GLN149C, GLN149E, GLU98C, GLU98E, GLY148C, GLY148E, GLY36C, GLY36E, GLY38C, GLY38E, GLY83C, GLY83E, HIS146C, HIS146E, LEU81C, LEU81E, LEU84C, LEU84E, LEU94C, LEU94E, LYS62C, LYS62E, LYS91C, LYS91E, MET93C, SER147E, SER85E, SER95C, SER95E, THR150C, THR150E, TRP99C, TRP99E, VAL82C, VAL82E
• C-F: ALA28F, ARG33C, ARG72F, ARG74F, ARG92C, ASN39C, ASN97C, ASP125C, ASP153C, ASP32F, ASP37C, ASP39F, ASP52F, CYS40C, GLN149C, GLN31F, GLN34C, GLN40F, GLN41F, GLU24F, GLU34F, GLU98C, GLY148C, GLY35F, GLY36C, GLY38C, GLY75F, HIS146C, HIS151C, ILE30F, ILE31C, ILE36F, LEU145C, LEU71F, LEU73F, LYS27F, LYS29F, LYS33F, PHE152C, PRO35C, PRO37F, PRO38F, SER124C, SER147C, THR150C, TRP99C, VAL121C
• D-E: ALA28D, ARG33E, ARG72D, ARG74D, ASN39E, ASN97E, ASP125E, ASP153E, ASP32D, ASP37E, ASP39D, ASP52D, CYS40E, GLN149E, GLN31D, GLN34E, GLN40D, GLN41D, GLU24D, GLU34D, GLU98E, GLY148E, GLY35D, GLY36E, GLY38E, GLY75D, HIS146E, HIS151E, ILE30D, ILE31E, ILE36D, LEU145E, LEU71D, LEU73D, LYS27D, LYS33D, PHE152E, PRO35E, PRO37D, PRO38D, SER147E, THR150E, TRP99E, VAL121E
• D-F: ARG74D, ARG74F, ASP39D, ASP39F, GLY75D, GLY75F, PRO37F
• E-F: ALA105E, ALA129E, ALA14E, ALA46F, ALA79E, ARG22E, ARG42F, ARG72F, ARG74F, ARG80E, ARG92E, ASN20E, ASN39E, ASN97E, ASP37E, ASP39F, ASP52F, ASP8E, CYS40E, GLN11E, GLN149E, GLN16E, GLN40F, GLN41F, GLN49F, GLU104E, GLU128E, GLU51F, GLU76E, GLU78E, GLU98E, GLY100E, GLY10F, GLY130E, GLY148E, GLY38E, GLY47F, GLY75F, HIS146E, HIS151E, HIS68F, ILE118E, ILE131E, ILE13E, ILE36F, ILE44F, LEU103E, LEU145E, LEU43F, LEU50F, LEU69F, LEU71F, LEU73F, LEU81E, LEU84E, LEU8F, LYS11F, LYS132E, LYS27F, LYS48F, LYS6F, MET107E, MET93E, PHE133E, PHE152E, PHE41E, PHE45F, PRO21E, PRO37F, PRO38F, PRO77E, SER101E, SER106E, SER147E, SER19E, THR102E, THR10E, THR120E, THR150E, THR7F, THR9F, TRP119E, TRP99E, TRP9E, TYR17E, TYR42E, TYR59F, TYR73E, TYR89E, VAL121E, VAL127E, VAL12E, VAL18E, VAL70F, VAL82E
• G-H: ALA105G, ALA122G, ALA129G, ALA14G, ALA46H, ALA79G, ARG22G, ARG42H, ARG54H, ARG72H, ARG74H, ARG80G, ARG92G, ASN20G, ASN39G, ASN97G, ASP37G, ASP39H, ASP52H, ASP8G, CYS40G, GLN11G, GLN149G, GLN16G, GLN40H, GLN41H, GLN49H, GLU104G, GLU128G, GLU51H, GLU76G, GLU78G, GLU98G, GLY100G, GLY10H, GLY130G, GLY148G, GLY38G, GLY47H, GLY53H, GLY75H, HIS146G, HIS151G, HIS68H, ILE118G, ILE131G, ILE13G, ILE23H, ILE44H, LEU103G, LEU145G, LEU43H, LEU50H, LEU69H, LEU71H, LEU73H, LEU81G, LEU84G, LEU8H, LYS11H, LYS132G, LYS27H, LYS48H, LYS6H, MET107G, MET93G, PHE133G, PHE152G, PHE41G, PHE45H, PRO21G, PRO37H, PRO38H, PRO77G, SER101G, SER106G, SER147G, SER19G, THR102G, THR10G, THR120G, THR150G, THR7H, THR9H, TRP119G, TRP99G, TRP9G, TYR17G, TYR42G, TYR59H, TYR73G, TYR89G, VAL121G, VAL127G, VAL12G, VAL18G, VAL70H, VAL82G