3PG9

thermotoga maritima dah7p synthase in complex with inhibitor

• Total interactions analyzed: 28
• Total true interactions: 14
• Strongest Interaction:
  • Chains: B-F
  • Int. Res.: 183
  • Norm. En. per Res.: -3.0736
• Hub Node: B(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-69.5925	34.1474	-329.396	-364.8411	132	10	21	16389	3	35	41
A-F	-25.0849	-9.2484	-167.917	-202.2503	98	1	8	8280	12	42	41
A-G	-52.1162	-2.4267	-270.549	-325.0919	171	17	5	12428	14	104	86
B-D	0.0	12.2079	-13.8898	-1.6819	25	3	0	755	0	21	16
B-E	0.0	0.0	-1.8251	-1.8251	9	0	0	139	0	6	3
B-F	-100.4585	-83.1301	-378.887	-562.4757	183	17	5	15557	22	103	91
B-G	-26.2307	7.5138	-169.036	-187.7529	93	5	8	7869	12	42	43
C-D	-65.1893	32.0958	-323.397	-356.4906	129	13	22	15883	2	36	42
C-E	-33.0762	-5.8953	-161.533	-200.5045	101	7	8	8013	13	40	43
C-H	-54.2797	-55.2994	-240.651	-350.2301	168	12	5	11020	13	103	85
D-E	-85.025	-34.7574	-334.741	-454.5234	180	17	6	15465	17	108	94
D-H	-21.5191	12.4502	-171.858	-180.927	95	6	8	7909	12	43	43
E-H	-57.467	41.4715	-327.386	-343.3815	132	13	21	16281	2	35	40
F-G	-48.7617	47.3024	-313.876	-315.3353	128	7	21	15816	2	34	40

Interface residues

• A-B: ALA245A, ALA245B, ALA254A, ALA254B, ALA286A, ALA286B, ALA287A, ALA287B, ALA289A, ALA289B, ALA292A, ALA292B, ALA330A, ALA330B, ALA332A, ALA332B, ARG208A, ARG208B, ARG240A, ARG240B, ARG247A, ARG247B, ARG259A, ARG259B, ARG276A, ARG276B, ARG277B, ARG285A, ARG285B, ASN212A, ASN212B, ASN248A, ASN248B, ASP251A, ASP251B, ASP278A, ASP278B, ASP331A, ASP331B, GLU215A, GLU215B, GLU216A, GLU216B, GLU236A, GLU236B, GLU243A, GLU243B, GLU261A, GLU261B, GLU325A, GLU325B, GLY209A, GLY209B, GLY238A, GLY238B, GLY274A, GLY274B, GLY291A, GLY291B, GLY334A, GLY334B, ILE214A, ILE214B, ILE239A, ILE239B, ILE252A, ILE252B, ILE257A, ILE257B, ILE258A, ILE258B, ILE281A, ILE281B, ILE288A, ILE288B, LEU250A, LEU250B, LEU279A, LEU279B, LEU283A, LEU283B, LEU329A, LEU329B, LEU333A, LEU333B, LYS244A, LYS244B, LYS260A, LYS260B, LYS327A, LYS327B, LYS328A, LYS328B, LYS67A, LYS67B, MET211A, MET211B, MET326A, MET326B, PHE210A, PHE210B, PHE217A, PHE217B, PHE242A, PHE242B, PRO256A, PRO256B, PRO270A, PRO282A, PRO282B, SER253A, SER253B, SER273A, SER273B, SER284A, SER284B, THR213A, THR213B, THR241A, THR241B, THR246A, THR246B, THR249A, THR249B, VAL255A, VAL255B, VAL268A, VAL268B, VAL280A, VAL280B, VAL290A, VAL290B
• A-F: ARG240A, ARG240F, ARG36A, ARG36F, ARG46A, ARG46F, ARG64A, ARG64F, ASP44A, ASP44F, ASP45A, ASP45F, ASP57F, CYS28A, CYS28F, GLN34A, GLN34F, GLU243A, GLU243F, GLU261A, GLU261F, GLU35A, GLU35F, GLU60A, GLU60F, GLU75A, GLU75F, GLY33A, GLY33F, GLY40A, GLY40F, GLY43A, GLY43F, HIS29A, HIS29F, ILE2A, ILE2F, ILE30A, ILE30F, ILE39A, ILE39F, ILE41A, ILE41F, ILE42A, ILE42F, LEU26A, LEU26F, LEU5A, LEU5F, LEU66A, LEU66F, LYS244A, LYS244F, LYS260A, LYS260F, LYS27A, LYS27F, LYS32A, LYS32F, LYS67A, LYS67F, LYS6A, LYS6F, LYS70A, LYS70F, MET1A, MET1F, MET211A, MET211F, PHE210A, PHE210F, PHE242A, PHE242F, PHE76A, PHE76F, PRO7A, PRO7F, SER31A, SER31F, SER61A, SER61F, SER73A, THR241A, THR241F, THR37A, THR37F, VAL38A, VAL38F, VAL3A, VAL3F, VAL4A, VAL4F, VAL62A, VAL62F, VAL63A, VAL63F, VAL65A, VAL65F
• A-G: ALA129A, ALA165A, ALA185A, ALA185G, ALA188A, ALA306A, ALA306G, ALA50A, ALA50G, ARG133A, ARG133G, ARG186A, ARG186G, ARG192A, ARG192G, ARG208A, ARG240A, ARG240G, ARG247A, ARG247G, ARG276A, ARG276G, ARG277A, ARG277G, ARG46A, ARG46G, ARG64A, ASN187A, ASN187G, ASN190A, ASN190G, ASN212A, ASN212G, ASN226A, ASN226G, ASP13G, ASP169A, ASP169G, ASP170A, ASP278A, ASP278G, ASP309A, ASP309G, ASP315G, ASP51A, ASP51G, ASP57A, ASP57G, CYS58A, CYS58G, GLN140A, GLN140G, GLN189A, GLN189G, GLN312A, GLN312G, GLU168A, GLU168G, GLU215A, GLU216A, GLU216G, GLU222A, GLU222G, GLU302A, GLU302G, GLU304A, GLU304G, GLU54A, GLU54G, GLU60A, GLU60G, GLY143A, GLY167A, GLY167G, GLY209A, GLY209G, GLY275A, GLY275G, GLY310A, GLY310G, ILE214A, ILE214G, ILE239A, LEU166A, LEU166G, LEU171A, LEU193A, LEU194A, LEU194G, LEU20A, LEU20G, LEU219A, LEU219G, LEU307A, LEU307G, LEU318G, LEU56A, LEU56G, LYS131A, LYS16A, LYS16G, LYS244A, LYS244G, LYS305A, LYS305G, LYS311A, LYS311G, LYS52A, LYS52G, LYS6A, LYS6G, MET211A, MET211G, PHE139A, PHE139G, PHE191A, PHE191G, PHE210A, PHE210G, PHE242A, PHE242G, PHE53A, PHE53G, PRO132A, PRO132G, PRO136A, PRO136G, PRO303A, PRO303G, PRO68A, PRO68G, SER135A, SER135G, SER138A, SER138G, SER195G, SER220A, SER220G, SER227G, SER308A, SER308G, SER313A, SER313G, SER55A, SER55G, SER61A, SER61G, THR134A, THR134G, THR213A, THR213G, THR241A, THR241G, TYR130A, TYR137A, TYR137G, TYR223A, TYR223G, TYR24A, TYR24G, TYR47A, TYR47G, TYR69G, VAL48A, VAL48G, VAL49A, VAL49G, VAL59A, VAL59G, VAL62A, VAL62G
• B-D: ARG107D, ASN201B, ASP84B, ASP87B, GLN140D, GLU108D, GLU144D, GLU148D, GLU152D, GLY106D, GLY141D, GLY143D, GLY86B, LEU142D, LEU85B, LYS145D, LYS202B, LYS231B, LYS89B, MET111D, PRO203B, SER199B, TYR149D, TYR160B, TYR200B
• B-E: ARG107B, ASN25E, ASP155B, GLU152B, GLU22E, LYS156B, SER23E, TYR157B, TYR24E
• B-F: ALA129B, ALA129F, ALA165B, ALA165F, ALA185B, ALA185F, ALA188B, ALA188F, ALA306B, ALA306F, ALA50B, ALA50F, ARG133B, ARG133F, ARG186B, ARG186F, ARG192B, ARG192F, ARG208B, ARG240B, ARG240F, ARG276B, ARG276F, ARG277B, ARG277F, ARG46B, ARG46F, ARG64F, ASN187B, ASN187F, ASN190B, ASN190F, ASN212B, ASN212F, ASN226B, ASN226F, ASN25F, ASP13F, ASP169B, ASP169F, ASP170B, ASP170F, ASP278B, ASP278F, ASP309B, ASP309F, ASP315B, ASP44F, ASP45F, ASP51B, ASP51F, ASP57B, ASP57F, CYS58B, CYS58F, GLN140B, GLN140F, GLN189B, GLN189F, GLN312B, GLN312F, GLU164B, GLU164F, GLU168B, GLU168F, GLU215F, GLU216B, GLU216F, GLU222B, GLU222F, GLU302B, GLU302F, GLU304B, GLU304F, GLU54B, GLU54F, GLU60B, GLU60F, GLY143B, GLY143F, GLY167B, GLY167F, GLY209B, GLY209F, GLY275B, GLY275F, GLY310B, GLY310F, ILE214B, ILE214F, LEU166B, LEU166F, LEU171B, LEU171F, LEU193B, LEU193F, LEU194B, LEU20B, LEU20F, LEU219B, LEU219F, LEU26F, LEU307B, LEU307F, LEU318B, LEU56B, LEU56F, LYS131B, LYS131F, LYS16B, LYS16F, LYS196B, LYS196F, LYS19F, LYS244F, LYS305B, LYS305F, LYS311B, LYS311F, LYS52B, LYS52F, LYS6B, LYS6F, MET211B, MET211F, PHE139B, PHE139F, PHE191B, PHE191F, PHE210B, PHE210F, PHE217B, PHE242B, PHE242F, PHE53B, PHE53F, PRO132B, PRO132F, PRO136B, PRO136F, PRO303B, PRO303F, PRO68B, PRO68F, SER135B, SER135F, SER138B, SER138F, SER195B, SER23F, SER308B, SER308F, SER313B, SER313F, SER55B, SER55F, SER61B, SER61F, THR134B, THR134F, THR213B, THR213F, THR241B, THR241F, TYR130B, TYR130F, TYR137B, TYR137F, TYR223B, TYR223F, TYR24B, TYR24F, TYR47B, TYR47F, TYR69F, VAL48B, VAL48F, VAL49B, VAL49F, VAL59B, VAL59F, VAL62B, VAL62F
• B-G: ARG240B, ARG240G, ARG36B, ARG36G, ARG46B, ARG46G, ARG64B, ARG64G, ASP44B, ASP44G, ASP45B, ASP45G, CYS28B, CYS28G, GLN34B, GLN34G, GLU243B, GLU243G, GLU261B, GLU261G, GLU35B, GLU35G, GLU60B, GLU60G, GLU75B, GLU75G, GLY33B, GLY33G, GLY40B, GLY40G, GLY43B, GLY43G, HIS29B, HIS29G, ILE2B, ILE2G, ILE30B, ILE30G, ILE39B, ILE39G, ILE41B, ILE41G, ILE42B, ILE42G, LEU26B, LEU26G, LEU5B, LEU5G, LEU66B, LEU66G, LYS244B, LYS244G, LYS27B, LYS27G, LYS32B, LYS32G, LYS67B, LYS67G, LYS70B, LYS70G, MET1B, MET1G, MET211B, MET211G, PHE210B, PHE210G, PHE242B, PHE242G, PHE76B, PRO7B, PRO7G, SER31B, SER31G, SER61B, SER61G, SER73B, SER73G, THR241B, THR241G, THR37B, THR37G, VAL38B, VAL38G, VAL3B, VAL3G, VAL4B, VAL4G, VAL62B, VAL62G, VAL63B, VAL63G, VAL65B, VAL65G
• C-D: ALA245C, ALA245D, ALA254C, ALA254D, ALA286C, ALA286D, ALA287C, ALA287D, ALA289C, ALA289D, ALA292C, ALA292D, ALA330C, ALA330D, ALA332C, ALA332D, ARG208C, ARG208D, ARG240C, ARG240D, ARG247C, ARG247D, ARG259C, ARG259D, ARG276C, ARG276D, ARG285C, ARG285D, ASN212C, ASN212D, ASN248C, ASN248D, ASP251C, ASP251D, ASP278C, ASP278D, ASP331C, ASP331D, GLU215C, GLU215D, GLU216C, GLU216D, GLU236C, GLU243C, GLU243D, GLU261C, GLU261D, GLU325C, GLU325D, GLY209C, GLY209D, GLY238C, GLY238D, GLY274C, GLY274D, GLY291C, GLY291D, GLY334C, GLY334D, ILE214C, ILE214D, ILE239C, ILE239D, ILE252C, ILE252D, ILE257C, ILE257D, ILE258C, ILE258D, ILE281C, ILE281D, ILE288C, ILE288D, LEU250C, LEU250D, LEU279C, LEU279D, LEU283C, LEU283D, LEU329C, LEU329D, LEU333C, LEU333D, LYS244C, LYS244D, LYS260C, LYS260D, LYS327C, LYS327D, LYS328C, LYS328D, LYS67C, LYS67D, MET211C, MET211D, MET326C, MET326D, PHE210C, PHE210D, PHE217C, PHE217D, PHE242C, PHE242D, PRO256C, PRO256D, PRO282C, PRO282D, SER253C, SER253D, SER273C, SER273D, SER284C, SER284D, THR213C, THR213D, THR241C, THR241D, THR246C, THR246D, THR249C, THR249D, VAL255C, VAL255D, VAL268C, VAL268D, VAL280C, VAL280D, VAL290C, VAL290D
• C-E: ALA245E, ARG240C, ARG240E, ARG36C, ARG36E, ARG46C, ARG46E, ARG64C, ARG64E, ASN25E, ASP44C, ASP44E, ASP45C, ASP45E, CYS28C, CYS28E, GLN34C, GLN34E, GLU243C, GLU243E, GLU261C, GLU261E, GLU35C, GLU35E, GLU60C, GLU60E, GLU75C, GLU75E, GLY33C, GLY33E, GLY40C, GLY40E, GLY43C, GLY43E, GLY8C, HIS29C, HIS29E, ILE2C, ILE2E, ILE30C, ILE30E, ILE39C, ILE39E, ILE41C, ILE41E, ILE42C, ILE42E, LEU26C, LEU26E, LEU5C, LEU5E, LEU66C, LEU66E, LYS244C, LYS244E, LYS260C, LYS260E, LYS27C, LYS27E, LYS32C, LYS32E, LYS67C, LYS67E, LYS6C, LYS6E, LYS70C, LYS70E, MET1C, MET1E, MET211C, MET211E, PHE210C, PHE210E, PHE242C, PHE242E, PHE76C, PHE76E, PRO7C, PRO7E, SER31C, SER31E, SER61C, SER61E, SER73C, SER73E, THR241C, THR241E, THR37C, THR37E, VAL38C, VAL38E, VAL3C, VAL3E, VAL4C, VAL4E, VAL62C, VAL62E, VAL63C, VAL63E, VAL65C, VAL65E
• C-H: ALA129C, ALA165C, ALA185C, ALA188C, ALA306C, ALA306H, ALA50C, ALA50H, ARG133C, ARG133H, ARG186C, ARG186H, ARG192C, ARG192H, ARG208C, ARG208H, ARG240C, ARG240H, ARG247C, ARG276C, ARG276H, ARG277C, ARG277H, ARG46C, ARG46H, ASN187C, ASN187H, ASN190C, ASN190H, ASN212C, ASN212H, ASN226C, ASN226H, ASP13H, ASP169C, ASP169H, ASP170C, ASP278C, ASP278H, ASP309C, ASP309H, ASP51C, ASP51H, ASP57C, ASP57H, CYS102C, CYS102H, CYS58C, CYS58H, GLN140C, GLN189C, GLN189H, GLN312C, GLN312H, GLU164C, GLU168C, GLU168H, GLU215H, GLU216C, GLU216H, GLU222C, GLU222H, GLU302C, GLU302H, GLU304C, GLU304H, GLU54C, GLU54H, GLU60C, GLU60H, GLY143C, GLY167C, GLY167H, GLY209C, GLY209H, GLY275C, GLY275H, GLY310C, GLY310H, HIS300H, ILE214C, ILE214H, LEU166C, LEU166H, LEU171C, LEU193C, LEU193H, LEU194H, LEU20C, LEU20H, LEU219C, LEU219H, LEU307C, LEU307H, LEU56C, LEU56H, LYS131C, LYS131H, LYS16C, LYS16H, LYS244C, LYS244H, LYS305C, LYS305H, LYS311C, LYS311H, LYS52C, LYS52H, LYS6C, LYS6H, MET211C, MET211H, PHE139C, PHE139H, PHE191C, PHE191H, PHE210C, PHE210H, PHE217H, PHE242C, PHE242H, PHE53C, PHE53H, PRO132C, PRO132H, PRO136C, PRO136H, PRO303C, PRO303H, PRO68C, PRO68H, SER135C, SER135H, SER138C, SER138H, SER195C, SER195H, SER308C, SER308H, SER313C, SER313H, SER55C, SER55H, SER61C, SER61H, THR134C, THR134H, THR213C, THR213H, THR241C, THR241H, TYR130C, TYR137C, TYR137H, TYR223C, TYR223H, TYR24C, TYR24H, TYR47C, TYR47H, VAL48C, VAL48H, VAL49C, VAL49H, VAL59C, VAL59H, VAL62C, VAL62H
• D-E: ALA129D, ALA129E, ALA165D, ALA165E, ALA185D, ALA188D, ALA188E, ALA306D, ALA306E, ALA50D, ALA50E, ARG133D, ARG133E, ARG186D, ARG186E, ARG192D, ARG192E, ARG208D, ARG240D, ARG240E, ARG276D, ARG276E, ARG277D, ARG277E, ARG46D, ARG46E, ASN187D, ASN187E, ASN190D, ASN190E, ASN212D, ASN212E, ASN226D, ASN226E, ASP169D, ASP169E, ASP170D, ASP170E, ASP278D, ASP278E, ASP309D, ASP309E, ASP51D, ASP51E, ASP57D, ASP57E, CYS58D, CYS58E, GLN140D, GLN140E, GLN189D, GLN189E, GLN312D, GLN312E, GLU105D, GLU164D, GLU164E, GLU168D, GLU168E, GLU215D, GLU215E, GLU216D, GLU216E, GLU222D, GLU222E, GLU302D, GLU302E, GLU304D, GLU304E, GLU54D, GLU54E, GLU60D, GLU60E, GLY143D, GLY143E, GLY167D, GLY167E, GLY209D, GLY209E, GLY275D, GLY275E, GLY310D, GLY310E, ILE214D, ILE214E, ILE224D, ILE239E, LEU166D, LEU166E, LEU171D, LEU171E, LEU193D, LEU193E, LEU194E, LEU20D, LEU20E, LEU219D, LEU219E, LEU307D, LEU307E, LEU56D, LEU56E, LEU71D, LYS131D, LYS131E, LYS16D, LYS16E, LYS196D, LYS196E, LYS19D, LYS305D, LYS305E, LYS311D, LYS311E, LYS52D, LYS52E, LYS6D, LYS6E, MET211D, MET211E, PHE139D, PHE139E, PHE191D, PHE191E, PHE210D, PHE210E, PHE217D, PHE242D, PHE242E, PHE53D, PHE53E, PRO132D, PRO132E, PRO136D, PRO136E, PRO303D, PRO303E, PRO68D, PRO68E, SER135D, SER135E, SER138D, SER138E, SER195D, SER220D, SER220E, SER23D, SER308D, SER308E, SER313D, SER313E, SER55D, SER55E, SER61E, THR134D, THR134E, THR213D, THR213E, THR241D, THR241E, TYR130D, TYR130E, TYR137D, TYR137E, TYR223D, TYR223E, TYR24D, TYR24E, TYR47D, TYR47E, TYR69D, TYR69E, VAL48D, VAL48E, VAL49D, VAL49E, VAL59D, VAL59E, VAL62D, VAL62E
• D-H: ARG240D, ARG240H, ARG36D, ARG36H, ARG46D, ARG46H, ARG64D, ARG64H, ASN25H, ASP44D, ASP44H, ASP45D, ASP45H, CYS28D, CYS28H, GLN34D, GLN34H, GLU243D, GLU243H, GLU261D, GLU261H, GLU35D, GLU35H, GLU60D, GLU60H, GLU75D, GLU75H, GLY33D, GLY33H, GLY40D, GLY40H, GLY43D, GLY43H, GLY8D, HIS29D, HIS29H, ILE2D, ILE2H, ILE30D, ILE30H, ILE39D, ILE39H, ILE41D, ILE41H, ILE42D, ILE42H, LEU26D, LEU26H, LEU5D, LEU5H, LEU66D, LEU66H, LYS244D, LYS244H, LYS27D, LYS27H, LYS32D, LYS32H, LYS67D, LYS67H, LYS70D, LYS70H, MET1D, MET1H, MET211D, MET211H, PHE210D, PHE210H, PHE242D, PHE242H, PHE76D, PRO7D, PRO7H, SER31D, SER31H, SER61D, SER61H, SER73D, SER73H, THR241D, THR241H, THR37D, THR37H, VAL38D, VAL38H, VAL3D, VAL3H, VAL4D, VAL4H, VAL62D, VAL62H, VAL63D, VAL63H, VAL65D, VAL65H
• E-H: ALA245E, ALA245H, ALA254E, ALA254H, ALA286E, ALA286H, ALA287E, ALA287H, ALA289E, ALA289H, ALA292E, ALA292H, ALA330E, ALA330H, ALA332E, ALA332H, ARG208E, ARG208H, ARG240E, ARG240H, ARG247E, ARG247H, ARG259E, ARG259H, ARG276E, ARG276H, ARG277E, ARG285E, ARG285H, ASN212E, ASN212H, ASN248E, ASN248H, ASP251E, ASP251H, ASP278E, ASP278H, ASP331E, ASP331H, GLU215E, GLU215H, GLU216E, GLU216H, GLU236H, GLU243E, GLU243H, GLU261E, GLU261H, GLU325E, GLU325H, GLY209E, GLY209H, GLY238E, GLY238H, GLY274E, GLY274H, GLY291E, GLY291H, GLY334E, GLY334H, ILE214E, ILE214H, ILE239E, ILE239H, ILE252E, ILE252H, ILE257E, ILE257H, ILE258E, ILE258H, ILE281E, ILE281H, ILE288E, ILE288H, LEU218H, LEU250E, LEU250H, LEU279E, LEU279H, LEU283E, LEU283H, LEU329E, LEU329H, LEU333E, LEU333H, LYS244E, LYS244H, LYS260E, LYS260H, LYS327E, LYS327H, LYS328E, LYS328H, LYS67E, LYS67H, MET211E, MET211H, MET326E, MET326H, PHE210E, PHE210H, PHE217E, PHE217H, PHE242E, PHE242H, PRO256E, PRO256H, PRO282E, PRO282H, SER253E, SER253H, SER273E, SER273H, SER284E, SER284H, THR213E, THR213H, THR241E, THR241H, THR246E, THR246H, THR249E, THR249H, TYR69E, VAL255E, VAL255H, VAL268E, VAL268H, VAL280E, VAL290E, VAL290H, VAL335H
• F-G: ALA245F, ALA245G, ALA254F, ALA254G, ALA286F, ALA286G, ALA287F, ALA287G, ALA289F, ALA289G, ALA292G, ALA330F, ALA330G, ALA332F, ALA332G, ARG208F, ARG208G, ARG240F, ARG240G, ARG247F, ARG247G, ARG259F, ARG259G, ARG276F, ARG276G, ARG285F, ARG285G, ASN212F, ASN212G, ASN248F, ASN248G, ASP251F, ASP251G, ASP278F, ASP278G, ASP331F, ASP331G, GLU215F, GLU215G, GLU216F, GLU216G, GLU243F, GLU243G, GLU261F, GLU261G, GLU325F, GLU325G, GLY209F, GLY209G, GLY238F, GLY238G, GLY274F, GLY274G, GLY291F, GLY291G, GLY334F, GLY334G, ILE214F, ILE214G, ILE239F, ILE239G, ILE252F, ILE252G, ILE257F, ILE257G, ILE258F, ILE258G, ILE281F, ILE281G, ILE288F, ILE288G, LEU250F, LEU250G, LEU279F, LEU279G, LEU283F, LEU283G, LEU329F, LEU329G, LEU333F, LEU333G, LYS244F, LYS244G, LYS260F, LYS260G, LYS327F, LYS327G, LYS328F, LYS328G, LYS67F, LYS67G, MET211F, MET211G, MET326F, MET326G, PHE210F, PHE210G, PHE217F, PHE217G, PHE242F, PHE242G, PRO256F, PRO256G, PRO270F, PRO282F, PRO282G, SER253F, SER253G, SER273F, SER273G, SER284F, SER284G, THR213F, THR213G, THR241F, THR241G, THR246F, THR246G, THR249F, THR249G, VAL255F, VAL255G, VAL268F, VAL268G, VAL280F, VAL290F, VAL290G, VAL335G