3PD6

crystal structure of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-iv

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 296
  • Norm. En. per Res.: -4.0914
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-140.5958	-126.4821	-943.975	-1211.0529	296	37	12	35869	16	64	62
A-C	0.0	24.6056	-105.029	-80.4234	54	1	0	4600	0	22	25
A-D	0.0	0.0	-0.0004	-0.0004	2	0	0	1	0	2	3
B-C	0.0	0.0	-0.002	-0.002	4	0	0	2	0	1	3
B-D	-7.196	-10.2063	-10.355	-27.7573	15	0	0	402	0	7	10
C-D	-125.5659	-157.2581	-916.495	-1199.319	295	34	12	35474	16	67	62

Interface residues

• A-B: ALA137A, ALA137B, ALA142A, ALA142B, ALA172A, ALA172B, ALA240A, ALA240B, ALA245A, ALA245B, ALA278A, ALA278B, ALA298A, ALA298B, ALA301A, ALA301B, ALA66A, ALA66B, ALA83A, ALA83B, ALA85A, ALA85B, ALA88A, ALA88B, ARG125A, ARG139A, ARG139B, ARG147A, ARG147B, ARG153A, ARG153B, ARG170A, ARG170B, ARG287A, ARG287B, ARG303A, ARG303B, ARG313A, ARG313B, ARG325A, ARG325B, ARG407A, ARG407B, ARG68A, ARG68B, ARG81A, ARG81B, ASN164A, ASN164B, ASN215A, ASN215B, ASN237A, ASN237B, ASN270A, ASN270B, ASN318A, ASN318B, ASN322A, ASN322B, ASN91A, ASN91B, ASP171A, ASP171B, ASP297A, ASP297B, ASP42A, ASP42B, ASP93A, ASP93B, CYS272A, CYS272B, CYS295A, CYS295B, GLN130A, GLN130B, GLN146A, GLN146B, GLN204A, GLN204B, GLN307A, GLN307B, GLU203A, GLU203B, GLU286A, GLU286B, GLU299A, GLU299B, GLU300A, GLU300B, GLU305A, GLU305B, GLU37A, GLU37B, GLU84A, GLU84B, GLU95A, GLU95B, GLY134A, GLY134B, GLY136A, GLY136B, GLY141A, GLY141B, GLY163A, GLY163B, GLY268A, GLY268B, GLY282A, GLY282B, GLY285A, GLY285B, GLY323A, GLY323B, GLY39A, GLY39B, GLY65A, GLY65B, HIS165A, HIS165B, HIS35A, HIS35B, ILE132A, ILE132B, ILE168A, ILE168B, ILE269A, ILE269B, ILE310A, ILE310B, ILE312A, ILE312B, ILE326A, ILE326B, ILE330A, ILE44A, ILE44B, ILE87A, ILE87B, ILE99A, ILE99B, LEU138A, LEU138B, LEU145A, LEU145B, LEU238A, LEU238B, LEU283A, LEU283B, LEU308A, LEU308B, LEU311A, LEU311B, LEU315A, LEU315B, LEU321A, LEU321B, LEU45A, LEU45B, LEU77A, LEU77B, LEU92A, LEU92B, LEU97A, LEU97B, LYS150A, LYS150B, LYS234A, LYS234B, LYS236A, LYS236B, LYS279A, LYS296A, LYS296B, LYS302A, LYS302B, LYS309A, LYS309B, LYS73A, LYS73B, LYS90A, LYS90B, LYS94A, LYS94B, MET174B, MET281A, MET281B, MET380A, MET380B, MET38A, MET38B, PHE144A, PHE144B, PHE148A, PHE148B, PHE149A, PHE149B, PHE151A, PHE151B, PHE169A, PHE169B, PHE239A, PHE239B, PHE241A, PHE241B, PHE291A, PHE291B, PHE381A, PHE381B, PRO167A, PRO167B, PRO314A, PRO314B, PRO319A, PRO319B, PRO320A, PRO320B, PRO40A, PRO40B, PRO41A, PRO41B, PRO43A, PRO43B, PRO74A, PRO74B, PRO98A, PRO98B, SER133A, SER133B, SER143A, SER143B, SER152A, SER152B, SER205A, SER205B, SER276A, SER276B, SER306A, SER306B, SER30A, SER30B, SER317A, SER317B, SER31A, SER31B, THR131A, THR131B, THR135A, THR135B, THR166A, THR166B, THR34A, THR34B, TRP162A, TRP162B, TRP32A, TRP32B, TRP33A, TRP33B, TYR246A, TYR246B, TYR284A, TYR284B, TYR316A, TYR316B, TYR67A, TYR67B, TYR75A, TYR75B, TYR96A, TYR96B, VAL127A, VAL127B, VAL140A, VAL140B, VAL206A, VAL206B, VAL233A, VAL233B, VAL271A, VAL271B, VAL288A, VAL288B, VAL293A, VAL293B, VAL294A, VAL294B, VAL304A, VAL304B, VAL36A, VAL36B, VAL64A, VAL64B, VAL76A, VAL76B, VAL80A, VAL80B
• A-C: ALA172C, ARG153A, ARG153C, ARG170A, ARG170C, ARG180A, ARG180C, ASP154A, ASP154C, ASP171C, ASP197A, ASP197C, GLN146A, GLN146C, GLN175A, GLN175C, GLN177A, GLN177C, GLN204A, GLN204C, GLU196A, GLU196C, GLU203A, GLU203C, GLY173A, GLY173C, GLY178A, GLY178C, ILE201A, ILE201C, LEU176A, LEU176C, LEU238A, LYS150A, LYS150C, LYS200A, LYS200C, LYS236A, LYS236C, MET174A, MET174C, PHE149A, PHE149C, PHE151A, PHE151C, PHE156A, PHE156C, PHE169C, PRO202A, PRO202C, SER152A, SER152C, SER205A, SER205C
• A-D: GLN146D, LYS150A
• B-C: GLN146B, GLN175C, LYS150C, TRP32B
• B-D: ARG147D, ARG153B, ARG153D, GLN146B, GLN146D, GLN175B, GLN175D, GLU37B, GLU37D, GLY173B, GLY173D, HIS35B, HIS35D, MET174B, MET174D
• C-D: ALA137C, ALA137D, ALA142C, ALA142D, ALA172C, ALA172D, ALA240C, ALA240D, ALA245C, ALA245D, ALA278C, ALA278D, ALA298C, ALA298D, ALA301C, ALA301D, ALA66C, ALA66D, ALA83C, ALA83D, ALA85C, ALA85D, ALA88C, ALA88D, ARG125D, ARG139C, ARG139D, ARG147C, ARG147D, ARG153C, ARG153D, ARG170C, ARG170D, ARG287C, ARG287D, ARG303C, ARG303D, ARG313C, ARG313D, ARG325C, ARG325D, ARG407C, ARG407D, ARG68C, ARG68D, ARG81C, ARG81D, ASN164C, ASN164D, ASN215C, ASN215D, ASN237C, ASN237D, ASN270C, ASN270D, ASN318C, ASN318D, ASN322C, ASN322D, ASN91C, ASN91D, ASP171C, ASP171D, ASP297C, ASP297D, ASP42C, ASP42D, ASP93C, ASP93D, CYS272C, CYS272D, CYS295C, CYS295D, GLN130C, GLN130D, GLN146C, GLN146D, GLN204C, GLN204D, GLN307C, GLN307D, GLU203C, GLU203D, GLU286C, GLU286D, GLU299C, GLU299D, GLU300C, GLU300D, GLU305C, GLU305D, GLU37C, GLU37D, GLU49C, GLU84C, GLU84D, GLU95C, GLU95D, GLY134C, GLY134D, GLY136C, GLY136D, GLY141C, GLY141D, GLY163C, GLY163D, GLY268C, GLY282C, GLY282D, GLY285C, GLY285D, GLY323C, GLY323D, GLY39C, GLY39D, GLY65C, GLY65D, HIS165C, HIS165D, HIS35C, HIS35D, ILE132C, ILE132D, ILE168C, ILE168D, ILE269C, ILE269D, ILE310C, ILE310D, ILE312C, ILE312D, ILE326C, ILE326D, ILE44C, ILE44D, ILE87C, ILE87D, ILE99C, ILE99D, LEU138C, LEU138D, LEU145C, LEU145D, LEU238C, LEU238D, LEU283C, LEU283D, LEU308C, LEU308D, LEU311C, LEU311D, LEU315C, LEU315D, LEU321C, LEU321D, LEU45C, LEU45D, LEU77C, LEU77D, LEU92C, LEU92D, LEU97C, LEU97D, LYS150C, LYS150D, LYS234C, LYS234D, LYS236C, LYS236D, LYS279C, LYS296C, LYS296D, LYS302C, LYS302D, LYS309C, LYS309D, LYS73C, LYS73D, LYS90C, LYS90D, LYS94C, LYS94D, MET174C, MET174D, MET281C, MET281D, MET380C, MET38C, MET38D, PHE144C, PHE144D, PHE148C, PHE148D, PHE149C, PHE149D, PHE151C, PHE151D, PHE169C, PHE169D, PHE239C, PHE239D, PHE241C, PHE241D, PHE291C, PHE291D, PHE381C, PHE381D, PRO167C, PRO167D, PRO202D, PRO314C, PRO314D, PRO319C, PRO319D, PRO320C, PRO320D, PRO40C, PRO40D, PRO41C, PRO41D, PRO74C, PRO74D, PRO98C, PRO98D, SER133C, SER133D, SER143C, SER143D, SER152C, SER152D, SER205C, SER205D, SER276C, SER276D, SER306C, SER306D, SER30C, SER30D, SER317C, SER317D, SER31C, SER31D, THR131C, THR131D, THR135C, THR135D, THR166C, THR166D, THR34C, THR34D, TRP162C, TRP162D, TRP32C, TRP32D, TRP33C, TRP33D, TYR246C, TYR246D, TYR277C, TYR284C, TYR284D, TYR316C, TYR316D, TYR67C, TYR67D, TYR75C, TYR75D, TYR96C, TYR96D, VAL127C, VAL127D, VAL140C, VAL140D, VAL206C, VAL206D, VAL233C, VAL233D, VAL271C, VAL271D, VAL288C, VAL288D, VAL293C, VAL293D, VAL294C, VAL294D, VAL304C, VAL304D, VAL36C, VAL36D, VAL64C, VAL64D, VAL76C, VAL76D, VAL80C, VAL80D